iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053641

Ensembl Protein ID

ENSLAFP00000002418.3

UniProt Accession

G3SRB9; G3SRB9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

ARHGAP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000002896.3	ENSLAFT00000002896.3	ENSLAFP00000002418.3
ENSLAFG00000002896.3	ENSLAFT00000030999.1	ENSLAFP00000018839.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.30e-11	43.3	730	784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +k ++ y+ ea+++ eL+++ G v + + +++ + gWl+g  +l+gkrGl+P+n+v+ 
   Q: 730  RKARAVYPCEAEHSSELSFEIGAVFEDV-QTSREPGWLEG--TLNGKRGLIPQNYVKL 784
           67899***********************.***********..8*************85 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGLQPLEFSD CYLDSPWFRE RIRAHEAELE RTNKFIKELI KDGKNLIAAT KSLSAAQRKF 60
AHSLRDFKFE FIGDAETDDE RCIDASLREF SNFLKNLEEQ REIMALSVTE TLIKPLEKFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCTGC AGCCCCTGGA GTTTAGCGAC TGTTACCTCG ACAGCCCCTG GTTCAGGGAG 60
AGGATTCGTG CCCACGAAGC GGAGCTCGAG AGGACCAACA AGTTCATCAA AGAGCTTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:0007010--P:cytoskeleton organization
GO:0043066--P:negative regulation of apoptotic process
GO:0007165--P:signal transduction

KEGG

lav:100661848

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001253	Ailuropoda melanoleuca	92.62	0.00e+00	1428.00
IUUC-Apl-003297	Anas platyrhynchos	78.40	0.00e+00	1203.00
IUUC-Aca-005285	Anolis carolinensis	78.22	0.00e+00	1235.00
IUUC-Bta-012379	Bos taurus	91.60	0.00e+00	1363.00
IUUC-Cja-019182	Callithrix jacchus	91.48	0.00e+00	1385.00
IUUC-Cfa-021141	Canis familiaris	92.62	0.00e+00	1422.00
IUUC-Csa-023847	Chlorocebus sabaeus	92.10	0.00e+00	1305.00
IUUC-Cin-025725	Ciona intestinalis	39.90	1.00e-143	503.00
IUUC-Dre-027525	Danio rerio	60.61	0.00e+00	881.00
IUUC-Dno-029215	Dasypus novemcinctus	86.71	0.00e+00	939.00
IUUC-Dor-030308	Dipodomys ordii	81.61	0.00e+00	1112.00
IUUC-Ete-032666	Echinops telfairi	83.23	0.00e+00	802.00
IUUC-Eca-033545	Equus caballus	91.83	0.00e+00	1297.00
IUUC-Fca-036457	Felis catus	93.13	0.00e+00	1435.00
IUUC-Fal-036703	Ficedula albicollis	79.44	0.00e+00	1233.00
IUUC-Gga-040830	Gallus gallus	78.50	0.00e+00	1235.00
IUUC-Gac-041728	Gasterosteus aculeatus	56.73	0.00e+00	836.00
IUUC-Ggo-044569	Gorilla gorilla	89.78	0.00e+00	1252.00
IUUC-Hsa-045658	Homo sapiens	92.62	0.00e+00	1378.00
IUUC-Loc-051740	Lepisosteus oculatus	64.22	0.00e+00	967.00
IUUC-Mcc-055152	Macaca mulatta	92.62	0.00e+00	1426.00
IUUC-Mmr-061434	Microcebus murinus	92.51	0.00e+00	1305.00
IUUC-Mdo-062864	Monodelphis domestica	87.26	0.00e+00	1361.00
IUUC-Mmu-064061	Mus musculus	90.20	0.00e+00	1373.00
IUUC-Mlu-067375	Myotis lucifugus	91.14	0.00e+00	1275.00
IUUC-Nle-069319	Nomascus leucogenys	88.91	0.00e+00	710.00
IUUC-Ont-071443	Oreochromis niloticus	61.01	0.00e+00	913.00
IUUC-Oan-072978	Ornithorhynchus anatinus	82.80	0.00e+00	1105.00
IUUC-Ocu-074591	Oryctolagus cuniculus	86.04	0.00e+00	1232.00
IUUC-Ola-087508	Oryzias latipes	64.02	0.00e+00	777.00
IUUC-Oga-088922	Otolemur garnettii	86.74	1.00e-180	625.00
IUUC-Oar-089531	Ovis aries	91.35	0.00e+00	1375.00
IUUC-Ptr-091149	Pan troglodytes	91.48	0.00e+00	1370.00
IUUC-Pan-092591	Papio anubis	92.62	0.00e+00	1412.00
IUUC-Pma-094731	Petromyzon marinus	31.76	1.00e-19	92.40
IUUC-Pfo-097265	Poecilia formosa	60.10	0.00e+00	900.00
IUUC-Pab-097780	Pongo abelii	92.24	0.00e+00	1375.00
IUUC-Rno-104991	Rattus norvegicus	89.82	0.00e+00	1370.00
IUUC-Sha-107629	Sarcophilus harrisii	84.24	0.00e+00	1112.00
IUUC-Ssc-115511	Sus scrofa	75.75	0.00e+00	696.00
IUUC-Tgu-117458	Taeniopygia guttata	78.53	0.00e+00	1208.00
IUUC-Tru-117724	Takifugu rubripes	63.48	0.00e+00	776.00
IUUC-Tbe-128126	Tupaia belangeri	27.65	4.00e-06	46.60
IUUC-Ttr-129045	Tursiops truncatus	88.96	0.00e+00	1239.00
IUUC-Xtr-132112	Xenopus tropicalis	70.31	0.00e+00	1080.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence