iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012437

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Glutamate-rich WD repeat-containing protein 1

Genbank Nucleotide ID

BC116037

Gene Name

GRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000000080.4	ENSBTAT00000000088.4	ENSBTAP00000000088.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-25	87.3	259	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           gHt sv +l++  ++ t ++s+s D +i++WD+r  
   Q: 259  GHTRSVEDLQWspTEdTVFASCSADASIRIWDIRAA 294
           8***********744799**************9865 PP

Organism

Bos taurus

Functional Description
(View)

Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness.

Protein Sequence
(Fasta)

MAALKGRRRT CEPGESMETE SQETGSKGQA QVYLPGRGPP LREGEELVMD EEAYVLYHRA 60
QTGAPCLSFD IVRDHLGDNR TELPLTLYLC AGTQAESSQS NRLMMLRMHN LHGTKPPPPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGATGGCG GCGCTCAAGG GTCGTCGGCG CACGTGTGAA CCTGGGGAGT CTATGGAGAC 60
CGAATCCCAA GAAACAGGGT CCAAGGGCCA GGCTCAGGTC TATCTACCTG GCCGGGGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0158--Chromosome
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR022052--Histone-bd_RBBP4_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12265--CAF1C_H4-bd
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005694--C:chromosome
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0003688--F:DNA replication origin binding
GO:0042393--F:histone binding
GO:0003723--F:RNA binding
GO:0006260--P:DNA replication
GO:0006334--P:nucleosome assembly
GO:0006337--P:nucleosome disassembly

KEGG

bta:540739

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000677	Aegilops tauschii	41.94	2.00e-76	280.00
IUUC-Aml-002309	Ailuropoda melanoleuca	93.29	0.00e+00	835.00
IUUC-Atr-002461	Amborella trichopoda	45.01	1.00e-93	337.00
IUUC-Aca-004760	Anolis carolinensis	71.29	3.00e-171	594.00
IUUC-Aly-005405	Arabidopsis lyrata	41.65	4.00e-85	308.00
IUUC-Ath-007178	Arabidopsis thaliana	42.43	8.00e-86	310.00
IUUC-Ago-007735	Ashbya gossypii	34.98	2.00e-66	246.00
IUUC-Acl-008294	Aspergillus clavatus	41.91	2.00e-79	290.00
IUUC-Afl-008486	Aspergillus flavus	42.11	7.00e-78	284.00
IUUC-Afu-009019	Aspergillus fumigatus	41.00	1.00e-79	290.00
IUUC-Ani-009465	Aspergillus nidulans	41.97	1.00e-77	283.00
IUUC-Ang-009641	Aspergillus niger	40.83	5.00e-76	278.00
IUUC-Ate-010426	Aspergillus terreus	42.20	4.00e-80	291.00
IUUC-Ame-010856	Astyanax mexicanus	61.70	5.00e-148	517.00
IUUC-Bgr-012258	Blumeria graminis	37.63	7.00e-65	241.00
IUUC-Bci-013647	Botrytis cinerea	41.38	7.00e-78	284.00
IUUC-Bdi-014728	Brachypodium distachyon	44.93	3.00e-94	338.00
IUUC-Bol-015126	Brassica oleracea	41.14	5.00e-84	305.00
IUUC-Bra-017677	Brassica rapa	45.92	9.00e-42	163.00
IUUC-Cel-018454	Caenorhabditis elegans	43.29	8.00e-104	370.00
IUUC-Cja-018859	Callithrix jacchus	91.26	0.00e+00	810.00
IUUC-Cfa-020912	Canis familiaris	91.70	0.00e+00	820.00
IUUC-Cpo-021368	Cavia porcellus	91.48	0.00e+00	812.00
IUUC-Cre-022850	Chlamydomonas reinhardtii	44.13	2.00e-49	190.00
IUUC-Csa-023599	Chlorocebus sabaeus	92.38	0.00e+00	827.00
IUUC-Cin-025718	Ciona intestinalis	56.09	2.00e-141	495.00
IUUC-Csv-025806	Ciona savignyi	57.10	6.00e-106	377.00
IUUC-Cgl-026766	Colletotrichum gloeosporioides	39.20	2.00e-66	246.00
IUUC-Cne-026781	Cryptococcus neoformans	43.62	2.00e-83	303.00
IUUC-Cme-027129	Cyanidioschyzon merolae	38.49	2.00e-43	170.00
IUUC-Dre-028225	Danio rerio	62.47	8.00e-151	526.00
IUUC-Dno-029792	Dasypus novemcinctus	91.13	0.00e+00	798.00
IUUC-Dor-030773	Dipodomys ordii	89.25	2.00e-106	379.00
IUUC-Dse-031289	Dothistroma septosporum	41.01	8.00e-78	284.00
IUUC-Dme-031676	Drosophila melanogaster	51.12	1.00e-128	452.00
IUUC-Ete-033042	Echinops telfairi	82.05	1.00e-62	233.00
IUUC-Eca-033618	Equus caballus	94.65	0.00e+00	817.00
IUUC-Fca-036102	Felis catus	92.63	0.00e+00	826.00
IUUC-Fox-037899	Fusarium oxysporum	40.39	2.00e-81	296.00
IUUC-Fso-038130	Fusarium solani	41.21	2.00e-81	296.00
IUUC-Gmo-038741	Gadus morhua	62.83	2.00e-147	515.00
IUUC-Ggr-040086	Gaeumannomyces graminis	39.07	6.00e-77	281.00
IUUC-Gac-042243	Gasterosteus aculeatus	61.15	2.00e-148	518.00
IUUC-Gma-044177	Glycine max	42.59	6.00e-87	314.00
IUUC-Ggo-044564	Gorilla gorilla	92.38	0.00e+00	828.00
IUUC-Hsa-046021	Homo sapiens	93.05	0.00e+00	833.00
IUUC-Hvu-047721	Hordeum vulgare	44.52	4.00e-90	325.00
IUUC-Itr-048189	Ictidomys tridecemlineatus	91.70	0.00e+00	815.00
IUUC-Kpa-049271	Komagataella pastoris	36.76	1.00e-68	253.00
IUUC-Lch-049974	Latimeria chalumnae	62.67	6.00e-161	560.00
IUUC-Lpe-051388	Leersia perrieri	42.14	3.00e-73	268.00
IUUC-Lma-053010	Leptosphaeria maculans	40.60	8.00e-75	274.00
IUUC-Laf-054058	Loxodonta africana	93.27	0.00e+00	835.00
IUUC-Mcc-055246	Macaca mulatta	92.38	0.00e+00	823.00
IUUC-Meu-056795	Macropus eugenii	77.68	0.00e+00	677.00
IUUC-Mor-057175	Magnaporthe oryzae	39.19	2.00e-77	283.00
IUUC-Mpo-057388	Magnaporthe poae	38.41	4.00e-63	235.00
IUUC-Mtr-057752	Medicago truncatula	42.73	1.00e-83	303.00
IUUC-Mla-058904	Melampsora laricipopulina	40.67	2.00e-80	293.00
IUUC-Mvi-060525	Microbotryum violaceum	40.41	6.00e-74	271.00
IUUC-Mmr-060905	Microcebus murinus	94.17	0.00e+00	840.00
IUUC-Mmu-063428	Mus musculus	91.03	0.00e+00	819.00
IUUC-Mac-065276	Musa acuminata	43.91	6.00e-88	317.00
IUUC-Mpu-066062	Mustela putorius furo	92.84	0.00e+00	827.00
IUUC-Mlu-068115	Myotis lucifugus	97.73	3.00e-125	440.00
IUUC-Nfi-068512	Neosartorya fischeri	41.46	3.00e-76	278.00
IUUC-Ncr-068629	Neurospora crassa	39.70	3.00e-76	279.00
IUUC-Nle-070016	Nomascus leucogenys	87.89	0.00e+00	773.00
IUUC-Ont-072230	Oreochromis niloticus	62.59	7.00e-150	523.00
IUUC-Oan-072759	Ornithorhynchus anatinus	28.99	1.00e-49	189.00
IUUC-Ocu-074511	Oryctolagus cuniculus	92.39	0.00e+00	791.00
IUUC-Oba-075093	Oryza barthii	42.89	5.00e-84	304.00
IUUC-Obr-076130	Oryza brachyantha	44.18	3.00e-92	332.00
IUUC-Ogl-077167	Oryza glaberrima	44.88	2.00e-93	336.00
IUUC-Ogu-078111	Oryza glumaepatula	42.22	2.00e-79	291.00
IUUC-Oin-079162	Oryza indica	43.02	3.00e-85	308.00
IUUC-Olo-080909	Oryza longistaminata	36.39	4.00e-57	215.00
IUUC-Ome-081768	Oryza meridionalis	43.46	4.00e-81	295.00
IUUC-Oni-082453	Oryza nivara	43.20	1.00e-84	307.00
IUUC-Opu-084133	Oryza punctata	41.73	9.00e-73	268.00
IUUC-Oru-085056	Oryza rufipogon	41.16	6.00e-67	247.00
IUUC-Osa-085735	Oryza sativa	45.12	7.00e-93	334.00
IUUC-Ola-087066	Oryzias latipes	62.68	4.00e-145	507.00
IUUC-Olu-087594	Ostreococcus lucimarinus	38.37	3.00e-72	265.00
IUUC-Oga-087974	Otolemur garnettii	91.26	0.00e+00	815.00
IUUC-Oar-089902	Ovis aries	97.76	0.00e+00	868.00
IUUC-Ptr-090469	Pan troglodytes	86.10	0.00e+00	775.00
IUUC-Pan-092858	Papio anubis	92.83	0.00e+00	830.00
IUUC-Psi-094092	Pelodiscus sinensis	57.07	3.00e-95	341.00
IUUC-Pno-094919	Phaeosphaeria nodorum	39.57	1.00e-67	250.00
IUUC-Ppa-095849	Physcomitrella patens	40.64	5.00e-92	331.00
IUUC-Pfo-096535	Poecilia formosa	62.47	8.00e-147	513.00
IUUC-Pab-098478	Pongo abelii	93.50	0.00e+00	837.00
IUUC-Pop-100032	Populus trichocarpa	44.39	2.00e-90	326.00
IUUC-Pca-100403	Procavia capensis	94.83	5.00e-166	576.00
IUUC-Ppe-101997	Prunus persica	45.85	1.00e-94	340.00
IUUC-Pva-102423	Pteropus vampyrus	91.93	0.00e+00	819.00
IUUC-Pgr-103339	Puccinia graminis	42.28	4.00e-82	299.00
IUUC-Ptt-103937	Puccinia triticina	41.07	6.00e-81	295.00
IUUC-Pte-104051	Pyrenophora teres	40.14	6.00e-72	264.00
IUUC-Pyt-104644	Pyrenophora triticirepentis	40.37	2.00e-72	266.00
IUUC-Rno-106118	Rattus norvegicus	91.26	0.00e+00	792.00
IUUC-Sce-106330	Saccharomyces cerevisiae	36.34	2.00e-64	239.00
IUUC-Sha-106564	Sarcophilus harrisii	75.19	2.00e-155	541.00
IUUC-Sja-107969	Schizosaccharomyces japonicus	40.57	1.00e-84	306.00
IUUC-Spo-108351	Schizosaccharomyces pombe	40.43	5.00e-84	304.00
IUUC-Ssl-108452	Sclerotinia sclerotiorum	41.84	6.00e-79	288.00
IUUC-Smo-108943	Selaginella moellendorffii	42.69	6.00e-88	317.00
IUUC-Sit-109857	Setaria italica	45.39	6.00e-88	317.00
IUUC-Sly-111245	Solanum lycopersicum	42.92	3.00e-85	308.00
IUUC-Stu-112645	Solanum tuberosum	43.95	5.00e-92	331.00
IUUC-Sar-113342	Sorex araneus	88.28	0.00e+00	741.00
IUUC-Sbi-114359	Sorghum bicolor	44.01	3.00e-89	322.00
IUUC-Sre-115098	Sporisorium reilianum	43.79	7.00e-91	327.00
IUUC-Ssc-115496	Sus scrofa	93.50	0.00e+00	832.00
IUUC-Tru-117662	Takifugu rubripes	63.07	2.00e-144	505.00
IUUC-Tni-120564	Tetraodon nigroviridis	62.05	4.00e-126	444.00
IUUC-Tca-121710	Theobroma cacao	43.78	5.00e-90	324.00
IUUC-Tre-122239	Trichoderma reesei	41.86	4.00e-80	291.00
IUUC-Tvi-122589	Trichoderma virens	41.86	2.00e-81	296.00
IUUC-Tae-124597	Triticum aestivum	46.01	3.00e-95	342.00
IUUC-Tur-126135	Triticum urartu	46.20	4.00e-75	275.00
IUUC-Tme-127073	Tuber melanosporum	36.85	6.00e-59	221.00
IUUC-Ttr-128383	Tursiops truncatus	91.70	0.00e+00	800.00
IUUC-Uma-129345	Ustilago maydis	44.97	2.00e-93	336.00
IUUC-Vda-129893	Verticillium dahliae	40.90	1.00e-79	290.00
IUUC-Vvi-131067	Vitis vinifera	43.78	8.00e-89	320.00
IUUC-Xtr-132603	Xenopus tropicalis	71.46	2.00e-180	625.00
IUUC-Xma-133149	Xiphophorus maculatus	64.03	8.00e-152	530.00
IUUC-Yli-134459	Yarrowia lipolytica	37.39	8.00e-66	244.00
IUUC-Zma-135548	Zea mays	44.01	6.00e-88	318.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence