iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035839

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02200614

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000002157.2	ENSFCAT00000002157.2	ENSFCAP00000001994.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-27	92.1	305	335
E3 adaptor/Cullin RING/APC_C/CDC20	6.30e-151	501.9	169	473

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 305  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 335
           8**********98889**************9 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 169  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 257
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wna++lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +P+++++
   Q: 258  LSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT 346
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 347  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 435
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 436  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 473
           *********************************99875 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MDQDYERRLL RQIVVQNENT MPCVSTGRPA PTGAGRVPGW RGAASRAGSN FNPSFWRMGE 60
NEKSPSQNRK AKDATSDNGK DGLAYSALLK NELLGAGIEK VQDPQTEDRR LQPSTPEKKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCAGG ACTATGAGCG GCGCCTCCTC CGGCAGATCG TCGTTCAGAA CGAGAACACG 60
ATGCCCTGCG TGAGTACCGG GCGCCCTGCC CCCACTGGCG CCGGCCGGGT CCCGGGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0031572--P:G2 DNA damage checkpoint
GO:0070306--P:lens fiber cell differentiation
GO:0090344--P:negative regulation of cell aging
GO:0008284--P:positive regulation of cell proliferation
GO:0045732--P:positive regulation of protein catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	64.19	3.00e-114	405.00
IUUC-Aml-002003	Ailuropoda melanoleuca	89.72	0.00e+00	877.00
IUUC-Atr-002753	Amborella trichopoda	60.05	4.00e-128	451.00
IUUC-Apl-003212	Anas platyrhynchos	93.10	0.00e+00	934.00
IUUC-Aly-005442	Arabidopsis lyrata	57.41	9.00e-136	476.00
IUUC-Ath-006938	Arabidopsis thaliana	57.51	2.00e-134	472.00
IUUC-Ago-007784	Ashbya gossypii	49.42	2.00e-96	346.00
IUUC-Acl-008269	Aspergillus clavatus	58.87	8.00e-130	457.00
IUUC-Afl-008432	Aspergillus flavus	59.30	7.00e-129	454.00
IUUC-Afu-008829	Aspergillus fumigatus	59.26	1.00e-130	460.00
IUUC-Ani-009471	Aspergillus nidulans	58.45	7.00e-129	454.00
IUUC-Ang-009711	Aspergillus niger	59.14	8.00e-129	454.00
IUUC-Aor-010118	Aspergillus oryzae	59.30	7.00e-129	454.00
IUUC-Ate-010534	Aspergillus terreus	58.87	3.00e-129	455.00
IUUC-Ame-011011	Astyanax mexicanus	88.33	0.00e+00	842.00
IUUC-Bgr-012013	Blumeria graminis	59.48	2.00e-129	456.00
IUUC-Bta-012586	Bos taurus	93.91	0.00e+00	939.00
IUUC-Bci-013807	Botrytis cinerea	66.16	7.00e-124	437.00
IUUC-Bdi-014981	Brachypodium distachyon	70.49	6.00e-129	454.00
IUUC-Bol-016301	Brassica oleracea	56.81	1.00e-133	469.00
IUUC-Bra-017453	Brassica rapa	56.81	8.00e-134	470.00
IUUC-Cel-018472	Caenorhabditis elegans	65.51	5.00e-143	501.00
IUUC-Cja-019929	Callithrix jacchus	93.35	0.00e+00	930.00
IUUC-Cfa-020977	Canis familiaris	93.55	0.00e+00	934.00
IUUC-Cpo-021537	Cavia porcellus	93.71	0.00e+00	937.00
IUUC-Csa-023389	Chlorocebus sabaeus	93.71	0.00e+00	935.00
IUUC-Cin-025327	Ciona intestinalis	72.24	5.00e-176	610.00
IUUC-Csv-025921	Ciona savignyi	65.16	0.00e+00	645.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	60.26	7.00e-130	457.00
IUUC-Cne-026933	Cryptococcus neoformans	59.58	2.00e-127	449.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.70	7.00e-118	418.00
IUUC-Dre-027470	Danio rerio	87.90	0.00e+00	838.00
IUUC-Dno-029629	Dasypus novemcinctus	84.11	0.00e+00	748.00
IUUC-Dor-030187	Dipodomys ordii	87.50	0.00e+00	868.00
IUUC-Dse-031502	Dothistroma septosporum	49.57	4.00e-122	431.00
IUUC-Dme-031858	Drosophila melanogaster	68.99	0.00e+00	664.00
IUUC-Ete-032562	Echinops telfairi	81.74	0.00e+00	791.00
IUUC-Eca-034210	Equus caballus	94.12	0.00e+00	940.00
IUUC-Fal-036895	Ficedula albicollis	92.90	0.00e+00	931.00
IUUC-Fox-037814	Fusarium oxysporum	64.29	2.00e-123	434.00
IUUC-Fso-038420	Fusarium solani	63.29	4.00e-129	454.00
IUUC-Gmo-039544	Gadus morhua	84.91	0.00e+00	815.00
IUUC-Ggr-039774	Gaeumannomyces graminis	65.87	9.00e-130	457.00
IUUC-Gga-041025	Gallus gallus	92.90	0.00e+00	931.00
IUUC-Gac-041279	Gasterosteus aculeatus	86.69	0.00e+00	869.00
IUUC-Gma-042657	Glycine max	60.20	2.00e-131	462.00
IUUC-Ggo-045599	Gorilla gorilla	92.94	0.00e+00	892.00
IUUC-Hsa-046695	Homo sapiens	93.15	0.00e+00	928.00
IUUC-Hvu-047486	Hordeum vulgare	65.95	2.00e-106	378.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	93.10	0.00e+00	934.00
IUUC-Kpa-049239	Komagataella pastoris	58.50	7.00e-122	430.00
IUUC-Lch-049827	Latimeria chalumnae	91.28	0.00e+00	881.00
IUUC-Lpe-051568	Leersia perrieri	64.36	1.00e-110	393.00
IUUC-Loc-052856	Lepisosteus oculatus	89.49	0.00e+00	862.00
IUUC-Laf-054321	Loxodonta africana	80.44	2.00e-93	336.00
IUUC-Mcc-055601	Macaca mulatta	93.71	0.00e+00	935.00
IUUC-Meu-056276	Macropus eugenii	72.49	3.00e-161	560.00
IUUC-Mor-057113	Magnaporthe oryzae	63.58	9.00e-130	457.00
IUUC-Mpo-057599	Magnaporthe poae	65.87	8.00e-130	457.00
IUUC-Mtr-057689	Medicago truncatula	60.40	7.00e-134	470.00
IUUC-Mla-059048	Melampsora laricipopulina	53.36	2.00e-115	409.00
IUUC-Mga-060097	Meleagris gallopavo	86.92	0.00e+00	858.00
IUUC-Mvi-060465	Microbotryum violaceum	50.61	2.00e-126	445.00
IUUC-Mmr-061151	Microcebus murinus	84.27	0.00e+00	803.00
IUUC-Mdo-063062	Monodelphis domestica	92.70	0.00e+00	931.00
IUUC-Mmu-063731	Mus musculus	93.51	0.00e+00	936.00
IUUC-Mac-065208	Musa acuminata	61.18	7.00e-126	443.00
IUUC-Mpu-066173	Mustela putorius furo	93.71	0.00e+00	934.00
IUUC-Mlu-068030	Myotis lucifugus	93.35	0.00e+00	934.00
IUUC-Nfi-068536	Neosartorya fischeri	59.52	2.00e-131	462.00
IUUC-Ncr-068734	Neurospora crassa	67.48	4.00e-132	464.00
IUUC-Nle-070163	Nomascus leucogenys	93.71	0.00e+00	935.00
IUUC-Opr-070974	Ochotona princeps	91.78	3.00e-155	540.00
IUUC-Ont-072272	Oreochromis niloticus	85.40	0.00e+00	825.00
IUUC-Oan-073634	Ornithorhynchus anatinus	99.66	5.00e-175	606.00
IUUC-Oba-075417	Oryza barthii	64.67	1.00e-110	393.00
IUUC-Obr-076123	Oryza brachyantha	69.51	5.00e-126	444.00
IUUC-Ogl-077294	Oryza glaberrima	70.16	4.00e-126	444.00
IUUC-Ogu-077996	Oryza glumaepatula	69.84	7.00e-125	440.00
IUUC-Oin-080172	Oryza indica	70.16	6.00e-126	444.00
IUUC-Olo-081068	Oryza longistaminata	70.16	4.00e-126	444.00
IUUC-Ome-081250	Oryza meridionalis	70.16	4.00e-126	444.00
IUUC-Oni-083048	Oryza nivara	70.16	4.00e-126	444.00
IUUC-Opu-083333	Oryza punctata	70.16	5.00e-126	444.00
IUUC-Oru-085001	Oryza rufipogon	70.16	4.00e-126	444.00
IUUC-Osa-086243	Oryza sativa	70.16	4.00e-126	444.00
IUUC-Ola-087094	Oryzias latipes	84.83	0.00e+00	785.00
IUUC-Oga-088911	Otolemur garnettii	94.12	0.00e+00	941.00
IUUC-Oar-089508	Ovis aries	93.91	0.00e+00	939.00
IUUC-Ptr-090967	Pan troglodytes	79.70	3.00e-174	604.00
IUUC-Pan-092147	Papio anubis	93.15	0.00e+00	928.00
IUUC-Psi-093702	Pelodiscus sinensis	92.53	0.00e+00	924.00
IUUC-Pma-094581	Petromyzon marinus	81.08	0.00e+00	771.00
IUUC-Pno-095139	Phaeosphaeria nodorum	59.76	1.00e-112	400.00
IUUC-Ppa-095192	Physcomitrella patens	61.18	1.00e-139	489.00
IUUC-Pfo-096309	Poecilia formosa	86.29	0.00e+00	831.00
IUUC-Pab-098762	Pongo abelii	76.01	0.00e+00	707.00
IUUC-Pop-098924	Populus trichocarpa	60.61	1.00e-130	459.00
IUUC-Pca-100565	Procavia capensis	88.50	0.00e+00	819.00
IUUC-Ppe-101924	Prunus persica	57.27	4.00e-133	468.00
IUUC-Pva-102602	Pteropus vampyrus	90.51	0.00e+00	889.00
IUUC-Pgr-103466	Puccinia graminis	50.77	4.00e-114	405.00
IUUC-Ptt-103888	Puccinia triticina	53.71	3.00e-107	382.00
IUUC-Pte-104097	Pyrenophora teres	60.16	6.00e-126	444.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	44.21	4.00e-108	385.00
IUUC-Rno-105028	Rattus norvegicus	93.10	0.00e+00	931.00
IUUC-Sce-106240	Saccharomyces cerevisiae	48.55	2.00e-94	339.00
IUUC-Sha-107107	Sarcophilus harrisii	78.60	0.00e+00	771.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	57.61	2.00e-114	405.00
IUUC-Spo-108056	Schizosaccharomyces pombe	49.05	2.00e-111	395.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	52.07	1.00e-125	443.00
IUUC-Smo-108878	Selaginella moellendorffii	60.28	8.00e-141	493.00
IUUC-Sit-110550	Setaria italica	57.84	3.00e-126	444.00
IUUC-Sly-111446	Solanum lycopersicum	57.78	1.00e-130	459.00
IUUC-Stu-112491	Solanum tuberosum	57.51	8.00e-130	457.00
IUUC-Sar-112962	Sorex araneus	80.15	3.00e-119	420.00
IUUC-Sbi-114489	Sorghum bicolor	70.16	7.00e-122	430.00
IUUC-Sre-115222	Sporisorium reilianum	47.61	1.00e-129	456.00
IUUC-Ssc-116171	Sus scrofa	93.71	0.00e+00	939.00
IUUC-Tgu-116878	Taeniopygia guttata	81.44	0.00e+00	792.00
IUUC-Tru-118222	Takifugu rubripes	85.17	0.00e+00	822.00
IUUC-Tni-119863	Tetraodon nigroviridis	86.09	0.00e+00	827.00
IUUC-Tca-121599	Theobroma cacao	57.18	3.00e-130	458.00
IUUC-Tre-122249	Trichoderma reesei	50.81	6.00e-130	457.00
IUUC-Tvi-122675	Trichoderma virens	60.99	3.00e-130	458.00
IUUC-Tae-123489	Triticum aestivum	69.84	5.00e-128	451.00
IUUC-Tur-126545	Triticum urartu	59.94	1.00e-103	369.00
IUUC-Tme-127151	Tuber melanosporum	63.52	7.00e-142	497.00
IUUC-Tbe-128056	Tupaia belangeri	89.69	2.00e-168	584.00
IUUC-Ttr-129055	Tursiops truncatus	92.54	0.00e+00	918.00
IUUC-Uma-129555	Ustilago maydis	57.36	5.00e-129	454.00
IUUC-Vda-130027	Verticillium dahliae	49.03	4.00e-130	458.00
IUUC-Vvi-131749	Vitis vinifera	55.23	1.00e-130	459.00
IUUC-Xtr-132808	Xenopus tropicalis	87.02	0.00e+00	868.00
IUUC-Xma-133183	Xiphophorus maculatus	86.29	0.00e+00	831.00
IUUC-Yli-134584	Yarrowia lipolytica	64.47	1.00e-130	459.00
IUUC-Zma-135717	Zea mays	70.16	4.00e-121	428.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence