iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041279

UUCD1 version

UUC-GaA-00532

Ensembl Protein ID

ENSGACP00000014206.1

UniProt Accession

G3P9D2; G3P9D2_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000010712.1	ENSGACT00000014212.1	ENSGACP00000014187.1
ENSGACG00000010712.1	ENSGACT00000014231.1	ENSGACP00000014206.1
ENSGACG00000010712.1	ENSGACT00000014238.1	ENSGACP00000014213.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	2.60e-148	493.6	174	478
E3 adaptor/Cullin RING/DCX/DWD	1.40e-25	88.7	310	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+ + kk
   Q: 174  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGYVQIWDAGAGKK 262
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           ++ l+gh+arvgaL+Wna++lssGsrd++il+rdvr++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +Pl+++ 
   Q: 263  LFALEGHTARVGALAWNADQLSSGSRDRMILQRDVRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPLQTYM 351
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           +h aavkaiawsP+q++lLasGGGtaDrci+fwntlt++ l+++dtgsqvc+l+wsk+++elvsthG+++n+i +wkyp l++va+l+g
   Q: 352  DHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTSQPLQCMDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPALTQVAKLTG 440
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 441  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 478
           *********************************99875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH  +v++l++ +d  ll+sG++D+++ vW+ 
   Q: 310  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWNH 341
           8**********98889**************95 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MDSEYEHRLL RQINLQNDNL SPIKQTLRQT PTGSPLSSPS KLGDRFIPTR AGANWSINFH 60
RINENEKSPS QNRKTKDASS DNLKADGQAY SALLKNELLG AGIEKILDPQ TEDRRLQPST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTGATCTG AAATAAACCG AATTACATTC GCTGCAGATC TGGGAGTGAA CAACTTGAAA 60
TACAACGCTT AGTTTATTAA TCTGATCTAA TCCTTGAATT GTTGGTCCCG TTCGGCGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002003	Ailuropoda melanoleuca	86.55	0.00e+00	873.00
IUUC-Acl-008269	Aspergillus clavatus	50.10	1.00e-134	473.00
IUUC-Afl-008432	Aspergillus flavus	50.30	2.00e-133	469.00
IUUC-Afu-008829	Aspergillus fumigatus	50.20	1.00e-135	476.00
IUUC-Ani-009471	Aspergillus nidulans	50.51	4.00e-133	468.00
IUUC-Ang-009711	Aspergillus niger	50.52	7.00e-132	464.00
IUUC-Aor-010118	Aspergillus oryzae	50.30	2.00e-133	469.00
IUUC-Ate-010534	Aspergillus terreus	50.10	3.00e-133	468.00
IUUC-Bci-013807	Botrytis cinerea	50.50	7.00e-126	444.00
IUUC-Cja-019929	Callithrix jacchus	89.56	0.00e+00	916.00
IUUC-Cfa-020977	Canis familiaris	89.76	0.00e+00	916.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	50.38	2.00e-134	472.00
IUUC-Dor-030187	Dipodomys ordii	80.52	0.00e+00	804.00
IUUC-Dse-031502	Dothistroma septosporum	49.60	1.00e-128	453.00
IUUC-Ete-032562	Echinops telfairi	78.71	0.00e+00	779.00
IUUC-Eca-034210	Equus caballus	89.36	0.00e+00	915.00
IUUC-Fca-035839	Felis catus	86.69	0.00e+00	869.00
IUUC-Ggr-039774	Gaeumannomyces graminis	50.79	2.00e-133	469.00
IUUC-Gma-042657	Glycine max	56.28	7.00e-135	473.00
IUUC-Hsa-046695	Homo sapiens	89.36	0.00e+00	914.00
IUUC-Laf-054321	Loxodonta africana	56.97	9.00e-138	483.00
IUUC-Mor-057113	Magnaporthe oryzae	51.00	2.00e-133	469.00
IUUC-Mpo-057599	Magnaporthe poae	50.79	4.00e-133	468.00
IUUC-Mtr-057689	Medicago truncatula	55.87	4.00e-136	478.00
IUUC-Mlu-068030	Myotis lucifugus	89.76	0.00e+00	917.00
IUUC-Nfi-068536	Neosartorya fischeri	50.10	6.00e-136	477.00
IUUC-Ncr-068734	Neurospora crassa	53.62	3.00e-134	472.00
IUUC-Ont-072507	Oreochromis niloticus	90.78	0.00e+00	929.00
IUUC-Ptr-090967	Pan troglodytes	76.46	9.00e-172	596.00
IUUC-Pan-092147	Papio anubis	89.36	0.00e+00	914.00
IUUC-Pma-094581	Petromyzon marinus	81.75	0.00e+00	787.00
IUUC-Ppa-095952	Physcomitrella patens	56.83	3.00e-142	498.00
IUUC-Pca-100565	Procavia capensis	86.16	0.00e+00	834.00
IUUC-Pva-102602	Pteropus vampyrus	87.15	0.00e+00	877.00
IUUC-Sce-106240	Saccharomyces cerevisiae	48.42	1.00e-93	337.00
IUUC-Sha-107107	Sarcophilus harrisii	76.65	0.00e+00	766.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	52.00	5.00e-129	454.00
IUUC-Smo-108878	Selaginella moellendorffii	59.10	4.00e-145	508.00
IUUC-Sly-111446	Solanum lycopersicum	54.45	3.00e-133	468.00
IUUC-Tre-122249	Trichoderma reesei	51.20	5.00e-134	471.00
IUUC-Tvi-122675	Trichoderma virens	50.89	9.00e-134	470.00
IUUC-Tbe-128056	Tupaia belangeri	84.69	7.00e-161	559.00
IUUC-Ttr-129055	Tursiops truncatus	88.55	0.00e+00	901.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence