iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fox-037738

Ensembl Protein ID

FOXG_03729P0

UniProt Accession

A0A0D2XIH4; A0A0D2XIH4_FUSO4

Genbank Protein ID

KNB00048.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

DS231699

Gene Name

FOXG_03729

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FOXG_03729	FOXG_03729T0	FOXG_03729P0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.70e-34	114.2	56	92
UBD/Beta-Prp	6.30e-77	258.4	9	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW++ t ++l
   Q: 56   HDGPVRGVDFhKTqPLFVSGGDDYKIKVWSYQTRRCL 92
           99*********4459***************9999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
           t +++++s+ + ++f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ v+f+++++++v+g++D+ ikvw+++t+ c+ tl+gh d+v+++
   Q: 9    TKFESKSSRAKGIAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEEHDGPVRGVDFHKTQPLFVSGGDDYKIKVWSYQTRRCLFTLNGHLDYVRTV 105
           67889999***************************************************************************************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............................... 166
            f+ +  +++s+s+d+tir+w++++++ +  t +gh++  +c+++hp+++l+vs+slD+ vr+Wd+                               
   Q: 106  FFHHELPWILSASDDQTIRIWNWQNRSLIC-TMTGHNHYAMCAQFHPKEDLVVSASLDQSVRVWDIsglrkkhsaptsmsfedqmaranqnqtdmfg 201
           *****************************9.********************************************************9999999997 PP
   S: 167  ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
           +t+ +++   +gh++ v++++f+++++ +vs+++d+ vklw +++++   v+t++gh +n +   f+p++++++s+++D++ir+Wdl +++ +++++
   Q: 202  NTDAVVKFVLEGHDRGVNWVAFHPTMPLIVSAGDDRLVKLWRMSETKAweVDTCRGHFQNASGCLFHPHQDLILSAGEDKTIRVWDLNKRTAVQSFK 298
           777777666777********************************888778*********************************************** PP
   S: 262  lhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++n++++ +a+ +++ n +++g  d+ v+++kl++++p
   Q: 299  RENDRFWVIAA-HPEINLFAAG-HDNGVMVFKLERERP 334
           ***********.6666555555.478*******98775 PP

Organism

Fusarium oxysporum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MQSSPGMLTK FESKSSRAKG IAFHPKRPWI LVSLHSSTIQ LWDYRMGTLI DRFEEHDGPV 60
RGVDFHKTQP LFVSGGDDYK IKVWSYQTRR CLFTLNGHLD YVRTVFFHHE LPWILSASDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGTCCT CCCCGGGAAT GTTGACCAAG GTAGATTGCG ATGCAATTGC TTTGTTTCGC 60
TTGCTTGTGA TTACTGACAC TCTCCTTTGC ACAGTTCGAG TCTAAGTCCT CGCGAGCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	47.16	0.00e+00	1111.00
IUUC-Aml-001758	Ailuropoda melanoleuca	48.52	0.00e+00	1217.00
IUUC-Atr-002493	Amborella trichopoda	55.84	0.00e+00	968.00
IUUC-Apl-003385	Anas platyrhynchos	43.35	0.00e+00	904.00
IUUC-Aca-005154	Anolis carolinensis	71.56	2.00e-94	336.00
IUUC-Aly-006020	Arabidopsis lyrata	45.77	0.00e+00	1094.00
IUUC-Ath-007360	Arabidopsis thaliana	54.99	0.00e+00	964.00
IUUC-Ago-007992	Ashbya gossypii	51.14	0.00e+00	1235.00
IUUC-Acl-008027	Aspergillus clavatus	76.21	0.00e+00	1922.00
IUUC-Afl-008644	Aspergillus flavus	77.11	0.00e+00	1927.00
IUUC-Afu-008964	Aspergillus fumigatus	77.28	0.00e+00	1958.00
IUUC-Ani-009379	Aspergillus nidulans	83.21	0.00e+00	1521.00
IUUC-Ang-009756	Aspergillus niger	77.33	0.00e+00	1934.00
IUUC-Aor-010174	Aspergillus oryzae	77.03	0.00e+00	1924.00
IUUC-Ate-010302	Aspergillus terreus	77.25	0.00e+00	1980.00
IUUC-Ame-011229	Astyanax mexicanus	55.87	0.00e+00	1015.00
IUUC-Bgr-012300	Blumeria graminis	76.83	0.00e+00	1942.00
IUUC-Bta-012524	Bos taurus	48.87	0.00e+00	1211.00
IUUC-Bci-013781	Botrytis cinerea	82.31	0.00e+00	2100.00
IUUC-Bdi-014549	Brachypodium distachyon	47.28	0.00e+00	1116.00
IUUC-Bol-015925	Brassica oleracea	55.23	0.00e+00	962.00
IUUC-Bra-016978	Brassica rapa	54.63	0.00e+00	955.00
IUUC-Cel-018115	Caenorhabditis elegans	52.27	0.00e+00	902.00
IUUC-Cja-019107	Callithrix jacchus	47.60	0.00e+00	1199.00
IUUC-Cfa-020675	Canis familiaris	48.13	0.00e+00	1189.00
IUUC-Cpo-021813	Cavia porcellus	48.95	0.00e+00	1226.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	57.33	0.00e+00	1006.00
IUUC-Csa-023523	Chlorocebus sabaeus	48.87	0.00e+00	1231.00
IUUC-Cho-024704	Choloepus hoffmanni	63.26	1.00e-122	432.00
IUUC-Cin-025572	Ciona intestinalis	47.08	0.00e+00	1167.00
IUUC-Csv-025864	Ciona savignyi	55.12	0.00e+00	951.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	87.64	0.00e+00	2171.00
IUUC-Cne-027053	Cryptococcus neoformans	54.03	0.00e+00	1314.00
IUUC-Cme-027222	Cyanidioschyzon merolae	39.51	1.00e-138	486.00
IUUC-Dre-027421	Danio rerio	49.07	0.00e+00	1211.00
IUUC-Dno-029303	Dasypus novemcinctus	48.67	0.00e+00	1229.00
IUUC-Dor-030290	Dipodomys ordii	46.41	1.00e-147	515.00
IUUC-Dse-031543	Dothistroma septosporum	74.49	0.00e+00	1829.00
IUUC-Dme-031945	Drosophila melanogaster	47.59	0.00e+00	1145.00
IUUC-Ete-032873	Echinops telfairi	46.60	0.00e+00	1071.00
IUUC-Eca-033773	Equus caballus	47.91	0.00e+00	1180.00
IUUC-Eeu-034874	Erinaceus europaeus	35.90	5.00e-163	566.00
IUUC-Fca-035739	Felis catus	48.43	0.00e+00	1203.00
IUUC-Fal-037263	Ficedula albicollis	45.67	0.00e+00	1070.00
IUUC-Fso-038153	Fusarium solani	94.18	0.00e+00	2379.00
IUUC-Gmo-039602	Gadus morhua	45.21	0.00e+00	1105.00
IUUC-Ggr-039931	Gaeumannomyces graminis	85.81	0.00e+00	2125.00
IUUC-Gga-040590	Gallus gallus	48.50	0.00e+00	1222.00
IUUC-Gac-041318	Gasterosteus aculeatus	47.91	0.00e+00	1185.00
IUUC-Gma-043894	Glycine max	46.95	0.00e+00	1136.00
IUUC-Ggo-045029	Gorilla gorilla	48.52	0.00e+00	1222.00
IUUC-Hsa-046078	Homo sapiens	48.52	0.00e+00	1224.00
IUUC-Hvu-047556	Hordeum vulgare	47.46	0.00e+00	1121.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	39.98	0.00e+00	652.00
IUUC-Kpa-049256	Komagataella pastoris	53.40	0.00e+00	1342.00
IUUC-Lch-049706	Latimeria chalumnae	47.86	0.00e+00	1189.00
IUUC-Lpe-051316	Leersia perrieri	55.10	0.00e+00	973.00
IUUC-Loc-051867	Lepisosteus oculatus	38.34	0.00e+00	790.00
IUUC-Lma-053138	Leptosphaeria maculans	75.21	0.00e+00	1914.00
IUUC-Laf-053510	Loxodonta africana	48.91	0.00e+00	1223.00
IUUC-Mcc-055836	Macaca mulatta	48.60	0.00e+00	1221.00
IUUC-Meu-056238	Macropus eugenii	51.69	0.00e+00	716.00
IUUC-Mor-057172	Magnaporthe oryzae	86.58	0.00e+00	2203.00
IUUC-Mpo-057300	Magnaporthe poae	85.66	0.00e+00	2141.00
IUUC-Mtr-058248	Medicago truncatula	47.27	0.00e+00	1134.00
IUUC-Mla-059019	Melampsora laricipopulina	56.15	0.00e+00	1409.00
IUUC-Mga-059499	Meleagris gallopavo	48.51	0.00e+00	1217.00
IUUC-Mvi-060336	Microbotryum violaceum	65.14	0.00e+00	1194.00
IUUC-Mmr-061102	Microcebus murinus	48.52	0.00e+00	1213.00
IUUC-Mdo-062594	Monodelphis domestica	48.67	0.00e+00	1233.00
IUUC-Mmu-063736	Mus musculus	48.31	0.00e+00	1213.00
IUUC-Mac-065398	Musa acuminata	43.70	0.00e+00	1017.00
IUUC-Mpu-066701	Mustela putorius furo	47.78	0.00e+00	1213.00
IUUC-Mlu-067392	Myotis lucifugus	48.71	0.00e+00	1221.00
IUUC-Nfi-068270	Neosartorya fischeri	76.62	0.00e+00	1935.00
IUUC-Ncr-068892	Neurospora crassa	85.61	0.00e+00	2157.00
IUUC-Nle-069634	Nomascus leucogenys	60.21	0.00e+00	880.00
IUUC-Opr-070952	Ochotona princeps	36.93	2.00e-165	575.00
IUUC-Ont-072488	Oreochromis niloticus	47.78	0.00e+00	1194.00
IUUC-Ocu-074211	Oryctolagus cuniculus	48.79	0.00e+00	1222.00
IUUC-Oba-075761	Oryza barthii	55.22	0.00e+00	974.00
IUUC-Obr-076429	Oryza brachyantha	55.40	0.00e+00	972.00
IUUC-Ogl-077364	Oryza glaberrima	55.22	0.00e+00	974.00
IUUC-Ogu-078257	Oryza glumaepatula	55.04	0.00e+00	972.00
IUUC-Oin-079274	Oryza indica	55.10	0.00e+00	973.00
IUUC-Olo-080466	Oryza longistaminata	55.37	0.00e+00	966.00
IUUC-Ome-081993	Oryza meridionalis	57.43	0.00e+00	937.00
IUUC-Oni-082874	Oryza nivara	55.22	0.00e+00	973.00
IUUC-Opu-083885	Oryza punctata	46.47	0.00e+00	1114.00
IUUC-Oru-084274	Oryza rufipogon	55.10	0.00e+00	972.00
IUUC-Osa-085565	Oryza sativa	55.10	0.00e+00	972.00
IUUC-Ola-086921	Oryzias latipes	47.62	0.00e+00	1186.00
IUUC-Olu-087639	Ostreococcus lucimarinus	48.03	0.00e+00	1158.00
IUUC-Oga-087991	Otolemur garnettii	46.44	0.00e+00	1150.00
IUUC-Oar-089590	Ovis aries	48.95	0.00e+00	1227.00
IUUC-Ptr-090808	Pan troglodytes	48.52	0.00e+00	1222.00
IUUC-Pan-092475	Papio anubis	48.51	0.00e+00	1217.00
IUUC-Psi-093044	Pelodiscus sinensis	52.65	0.00e+00	863.00
IUUC-Pno-094839	Phaeosphaeria nodorum	74.72	0.00e+00	1839.00
IUUC-Ppa-095785	Physcomitrella patens	49.96	0.00e+00	1211.00
IUUC-Pfo-097493	Poecilia formosa	48.18	0.00e+00	1192.00
IUUC-Pab-098497	Pongo abelii	48.79	0.00e+00	1231.00
IUUC-Pop-099992	Populus trichocarpa	48.13	0.00e+00	1126.00
IUUC-Pca-100413	Procavia capensis	53.76	0.00e+00	628.00
IUUC-Ppe-101899	Prunus persica	55.96	0.00e+00	983.00
IUUC-Pva-102126	Pteropus vampyrus	46.92	0.00e+00	1159.00
IUUC-Pgr-103376	Puccinia graminis	55.70	0.00e+00	1410.00
IUUC-Ptt-103978	Puccinia triticina	50.04	0.00e+00	1193.00
IUUC-Pte-104126	Pyrenophora teres	73.95	0.00e+00	1818.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	66.57	0.00e+00	1401.00
IUUC-Rno-105428	Rattus norvegicus	48.51	0.00e+00	1223.00
IUUC-Sce-106464	Saccharomyces cerevisiae	50.99	0.00e+00	1219.00
IUUC-Sha-107301	Sarcophilus harrisii	48.29	0.00e+00	1201.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	52.08	0.00e+00	1323.00
IUUC-Spo-108217	Schizosaccharomyces pombe	54.96	0.00e+00	1396.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	81.90	0.00e+00	2095.00
IUUC-Smo-109582	Selaginella moellendorffii	56.92	0.00e+00	1010.00
IUUC-Sit-109697	Setaria italica	55.10	0.00e+00	974.00
IUUC-Sly-111759	Solanum lycopersicum	46.70	0.00e+00	1117.00
IUUC-Stu-112564	Solanum tuberosum	46.38	0.00e+00	1115.00
IUUC-Sar-113313	Sorex araneus	38.78	1.00e-154	538.00
IUUC-Sbi-114388	Sorghum bicolor	54.98	0.00e+00	972.00
IUUC-Sre-115209	Sporisorium reilianum	62.75	0.00e+00	1132.00
IUUC-Ssc-115933	Sus scrofa	48.87	0.00e+00	1226.00
IUUC-Tgu-117109	Taeniopygia guttata	37.91	9.00e-91	325.00
IUUC-Tru-117772	Takifugu rubripes	47.52	0.00e+00	1176.00
IUUC-Tsy-119105	Tarsius syrichta	47.17	0.00e+00	938.00
IUUC-Tni-120556	Tetraodon nigroviridis	37.31	0.00e+00	763.00
IUUC-Tca-121545	Theobroma cacao	56.66	0.00e+00	986.00
IUUC-Tre-121951	Trichoderma reesei	87.30	0.00e+00	2169.00
IUUC-Tvi-122359	Trichoderma virens	86.97	0.00e+00	2201.00
IUUC-Tae-123611	Triticum aestivum	47.16	0.00e+00	1110.00
IUUC-Tur-126754	Triticum urartu	47.42	0.00e+00	1106.00
IUUC-Tme-127170	Tuber melanosporum	74.33	0.00e+00	1930.00
IUUC-Tbe-127882	Tupaia belangeri	63.46	8.00e-123	433.00
IUUC-Ttr-128217	Tursiops truncatus	46.92	0.00e+00	1153.00
IUUC-Uma-129337	Ustilago maydis	62.16	0.00e+00	1125.00
IUUC-Vda-129828	Verticillium dahliae	84.26	0.00e+00	2125.00
IUUC-Vpa-130537	Vicugna pacos	48.28	0.00e+00	1204.00
IUUC-Vvi-130958	Vitis vinifera	55.96	0.00e+00	980.00
IUUC-Xtr-132857	Xenopus tropicalis	47.14	0.00e+00	1144.00
IUUC-Xma-133138	Xiphophorus maculatus	48.26	0.00e+00	1194.00
IUUC-Yli-134399	Yarrowia lipolytica	61.48	0.00e+00	1089.00
IUUC-Zma-135612	Zea mays	46.92	0.00e+00	1117.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence