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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-032136
Ensembl Protein ID FBpp0070862
UniProt Accession Q9W415; A8E6N7; A9YJ32; WUHO_DROME
Genbank Protein ID AAF46145.1; ABV82211.1; ABW92684.1; ABW92685.1; ABW92686.1; ABW92687.1; ABW92688.1; ABW92689.1; ABW92690.1; ABW92691.1; ABW92692.1; ABW92693.1; ABW92694.1; ABW92695.1
Protein Name tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho
Genbank Nucleotide ID AE014298; BT030829; EU217765; EU217766; EU217767; EU217768; EU217769; EU217770; EU217771; EU217772; EU217773; EU217774; EU217775; EU217776
Gene Name wuho; CG15897
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0029857 FBtr0070897 FBpp0070862
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 7.70e-10 38.7 227 261
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgv 34
           gH + v++la+ ++ +++s+s+D+t++vW++ +g+
   Q: 227  GHREFVSGLALlTEQHIASASGDKTLRVWNYIQGK 261
           79999*****98889***************87766 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Required during gametogenesis.
 Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Required during gametogenesis.
Protein Sequence
(Fasta)
MCTTISFAEP EIVLGHGRRV LFVNPDDLQI FKEIELPPDL GLKGHTSQSQ ESCTAAAAAS 60
TATAASGQAP GGKEQQLANQ PEEGGTSASA SGLGCATSTS VQNVAYSPDG QLLAVTTSGK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032136|E3,WD_repeat|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGTAGTCAG TAGTTGTGCA AACCTATCGG TGGCTATCGA ATCGAGTCGC AAGAATGTGC 60
ACAACAATTT CGTTCGCGGA ACCCGAAATC GTGCTCGGCC ATGGCCGCAG GGTGCTCTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032136|E3,WD_repeat|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0539--Nucleus
KW-0896--Oogenesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0744--Spermatogenesis
KW-0819--tRNA processing
KW-0853--WD repeat
Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0001674--C:female germ cell nucleus
GO:0001673--C:male germ cell nucleus
GO:0043527--C:tRNA methyltransferase complex
GO:0007275--P:multicellular organism development
GO:0048477--P:oogenesis
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0007283--P:spermatogenesis
GO:0008033--P:tRNA processing
KEGG dme:Dmel_CG15897
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003975 Anas platyrhynchos 41.07 2.00e-29 122.00
IUUC-Aca-005170 Anolis carolinensis 34.62 1.00e-23 103.00
IUUC-Aly-005769 Arabidopsis lyrata 31.32 2.00e-15 76.30
IUUC-Ath-006733 Arabidopsis thaliana 30.22 2.00e-15 75.90
IUUC-Acl-008151 Aspergillus clavatus 24.24 4.00e-11 62.00
IUUC-Afl-008518 Aspergillus flavus 35.79 5.00e-12 64.70
IUUC-Afu-009102 Aspergillus fumigatus 30.18 1.00e-09 57.40
IUUC-Ani-009442 Aspergillus nidulans 24.06 2.00e-14 73.20
IUUC-Aor-010133 Aspergillus oryzae 23.74 9.00e-13 67.40
IUUC-Ate-010465 Aspergillus terreus 32.67 2.00e-10 60.10
IUUC-Ame-010613 Astyanax mexicanus 36.99 8.00e-26 110.00
IUUC-Bgr-012067 Blumeria graminis 33.06 1.00e-11 63.90
IUUC-Bta-012788 Bos taurus 34.47 1.00e-27 117.00
IUUC-Bdi-014458 Brachypodium distachyon 29.78 1.00e-12 66.60
IUUC-Bol-016398 Brassica oleracea 30.46 3.00e-16 79.00
IUUC-Bra-016644 Brassica rapa 30.10 7.00e-16 79.00
IUUC-Cpo-021963 Cavia porcellus 37.50 8.00e-27 113.00
IUUC-Csa-024148 Chlorocebus sabaeus 36.36 4.00e-24 105.00
IUUC-Cne-026834 Cryptococcus neoformans 33.50 2.00e-19 90.10
IUUC-Dre-028427 Danio rerio 35.79 6.00e-26 110.00
IUUC-Dno-028881 Dasypus novemcinctus 29.89 2.00e-14 72.80
IUUC-Dor-030522 Dipodomys ordii 29.48 7.00e-27 114.00
IUUC-Fca-035833 Felis catus 39.88 6.00e-29 120.00
IUUC-Fal-037497 Ficedula albicollis 39.88 2.00e-29 122.00
IUUC-Gga-040547 Gallus gallus 40.48 3.00e-29 122.00
IUUC-Gac-041761 Gasterosteus aculeatus 34.60 4.00e-26 111.00
IUUC-Gma-043722 Glycine max 39.80 1.00e-13 70.10
IUUC-Ggo-045340 Gorilla gorilla 36.87 1.00e-24 106.00
IUUC-Hsa-046403 Homo sapiens 36.41 3.00e-25 108.00
IUUC-Hvu-047643 Hordeum vulgare 29.91 3.00e-15 75.50
IUUC-Itr-048103 Ictidomys tridecemlineatus 40.37 2.00e-27 115.00
IUUC-Kpa-049283 Komagataella pastoris 32.16 2.00e-22 99.80
IUUC-Lch-050682 Latimeria chalumnae 30.58 3.00e-34 138.00
IUUC-Lpe-050712 Leersia perrieri 28.81 1.00e-14 73.20
IUUC-Loc-052599 Lepisosteus oculatus 28.77 2.00e-34 139.00
IUUC-Laf-054390 Loxodonta africana 36.84 1.00e-28 119.00
IUUC-Mcc-054747 Macaca mulatta 36.36 9.00e-24 103.00
IUUC-Mtr-058600 Medicago truncatula 30.11 3.00e-17 82.40
IUUC-Mla-059129 Melampsora laricipopulina 25.53 1.00e-11 62.80
IUUC-Mga-059876 Meleagris gallopavo 38.86 2.00e-28 119.00
IUUC-Mvi-060359 Microbotryum violaceum 27.67 2.00e-10 59.70
IUUC-Mmr-061518 Microcebus murinus 34.95 2.00e-27 115.00
IUUC-Mac-065625 Musa acuminata 25.81 3.00e-13 68.60
IUUC-Nfi-068402 Neosartorya fischeri 30.18 5.00e-10 58.20
IUUC-Nle-069914 Nomascus leucogenys 33.98 1.00e-21 97.10
IUUC-Ont-071555 Oreochromis niloticus 42.24 3.00e-28 118.00
IUUC-Oan-072951 Ornithorhynchus anatinus 28.65 2.00e-32 132.00
IUUC-Ocu-074679 Oryctolagus cuniculus 38.69 6.00e-22 97.80
IUUC-Obr-076769 Oryza brachyantha 28.16 9.00e-16 77.40
IUUC-Ogl-077168 Oryza glaberrima 27.18 1.00e-14 73.60
IUUC-Oin-079207 Oryza indica 27.18 1.00e-14 73.60
IUUC-Opu-084031 Oryza punctata 27.18 8.00e-14 71.20
IUUC-Osa-085327 Oryza sativa 27.18 1.00e-14 73.60
IUUC-Ola-086716 Oryzias latipes 38.82 4.00e-27 114.00
IUUC-Olu-087708 Ostreococcus lucimarinus 25.52 6.00e-09 54.30
IUUC-Oar-090239 Ovis aries 39.88 3.00e-28 118.00
IUUC-Ptr-090851 Pan troglodytes 35.92 1.00e-24 106.00
IUUC-Pan-092558 Papio anubis 36.36 3.00e-24 105.00
IUUC-Psi-093792 Pelodiscus sinensis 42.60 6.00e-30 124.00
IUUC-Ppa-095757 Physcomitrella patens 32.95 1.00e-16 80.10
IUUC-Pfo-096465 Poecilia formosa 28.02 2.00e-28 119.00
IUUC-Pab-097722 Pongo abelii 30.97 2.00e-26 112.00
IUUC-Pop-098979 Populus trichocarpa 27.80 1.00e-14 73.60
IUUC-Pca-100753 Procavia capensis 37.59 5.00e-19 87.80
IUUC-Ppe-101515 Prunus persica 28.86 4.00e-14 71.60
IUUC-Sja-107780 Schizosaccharomyces japonicus 27.32 4.00e-16 78.20
IUUC-Spo-108251 Schizosaccharomyces pombe 27.41 9.00e-15 73.90
IUUC-Smo-108938 Selaginella moellendorffii 30.11 2.00e-15 76.30
IUUC-Sit-110020 Setaria italica 28.80 6.00e-15 74.70
IUUC-Sly-111543 Solanum lycopersicum 28.65 6.00e-15 74.70
IUUC-Stu-111925 Solanum tuberosum 29.19 2.00e-15 75.90
IUUC-Sbi-114061 Sorghum bicolor 28.80 8.00e-16 77.40
IUUC-Tgu-117321 Taeniopygia guttata 39.88 1.00e-25 109.00
IUUC-Tru-118454 Takifugu rubripes 35.50 4.00e-28 118.00
IUUC-Tni-119894 Tetraodon nigroviridis 35.82 2.00e-28 119.00
IUUC-Tca-121746 Theobroma cacao 31.08 2.00e-19 89.70
IUUC-Tae-124114 Triticum aestivum 29.46 6.00e-15 74.30
IUUC-Tur-126254 Triticum urartu 26.11 2.00e-07 49.30
IUUC-Tbe-127683 Tupaia belangeri 45.78 2.00e-12 65.90
IUUC-Ttr-129056 Tursiops truncatus 38.86 7.00e-30 124.00
IUUC-Vvi-131428 Vitis vinifera 28.27 2.00e-13 69.30
IUUC-Xma-133605 Xiphophorus maculatus 29.20 1.00e-27 116.00
Created Date 25-Jun-2017

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