iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022427

Ensembl Protein ID

ENSCPOP00000012160.2

UniProt Accession

H0VNW1; H0VNW1_CAVPO

Genbank Protein ID

ENSCPOP00000012160

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02023402

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013505.3	ENSCPOT00000013639.2	ENSCPOP00000012160.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.70e-59	195.2	1146	1198

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1146 QVIAMYDYVANNEDELNFSKGQLINVM--NKDDPDWWQG--EINGVTGLFPSNYVKM 1198
           6899**********************9..8899******..9*************85 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

NLSFMCVSGG PNMWAITSEE RTKHDKQFDH LKPSGGYITG DQARTFFLQS GLPAPVLAEI 60
WALSDLNKDG KMDQQEFSIA MKLIKLKLQG QQLPVVLPPI MKQPPMFSPL ISARFGMGSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTTGTCTT TCATGTGTGT TTCAGGAGGG CCAAACATGT GGGCTATTAC CTCCGAAGAA 60
CGAACTAAGC ATGACAAACA ATTTGATCAC CTCAAGCCTT CGGGAGGTTA CATAACAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	88.62	0.00e+00	1750.00
IUUC-Apl-004205	Anas platyrhynchos	75.65	0.00e+00	2384.00
IUUC-Ago-007935	Ashbya gossypii	30.47	1.00e-11	65.10
IUUC-Bta-013248	Bos taurus	86.14	0.00e+00	1680.00
IUUC-Cel-018490	Caenorhabditis elegans	36.09	2.00e-43	171.00
IUUC-Cfa-020628	Canis familiaris	88.72	0.00e+00	1758.00
IUUC-Csa-023122	Chlorocebus sabaeus	89.54	0.00e+00	1730.00
IUUC-Cne-026918	Cryptococcus neoformans	35.97	6.00e-39	157.00
IUUC-Dno-029419	Dasypus novemcinctus	88.49	0.00e+00	1739.00
IUUC-Dor-030504	Dipodomys ordii	75.38	0.00e+00	1436.00
IUUC-Dme-032099	Drosophila melanogaster	36.08	7.00e-43	169.00
IUUC-Eca-034196	Equus caballus	84.82	0.00e+00	1637.00
IUUC-Fca-035757	Felis catus	89.03	0.00e+00	1765.00
IUUC-Gga-041012	Gallus gallus	80.88	0.00e+00	1638.00
IUUC-Ggo-045405	Gorilla gorilla	79.52	0.00e+00	2499.00
IUUC-Hsa-046833	Homo sapiens	89.45	0.00e+00	1730.00
IUUC-Kpa-049215	Komagataella pastoris	35.00	6.00e-15	75.90
IUUC-Lch-050094	Latimeria chalumnae	66.33	0.00e+00	1573.00
IUUC-Laf-053798	Loxodonta africana	82.98	0.00e+00	1050.00
IUUC-Mcc-054709	Macaca mulatta	89.45	0.00e+00	1731.00
IUUC-Meu-056396	Macropus eugenii	78.10	0.00e+00	1520.00
IUUC-Mla-059128	Melampsora laricipopulina	34.44	1.00e-40	163.00
IUUC-Mga-059997	Meleagris gallopavo	83.30	0.00e+00	1701.00
IUUC-Mvi-060268	Microbotryum violaceum	30.85	1.00e-46	182.00
IUUC-Mmr-060891	Microcebus murinus	89.21	0.00e+00	1790.00
IUUC-Mmu-064226	Mus musculus	87.38	0.00e+00	1756.00
IUUC-Mpu-066431	Mustela putorius furo	88.48	0.00e+00	1750.00
IUUC-Mlu-068190	Myotis lucifugus	87.89	0.00e+00	1747.00
IUUC-Nle-070116	Nomascus leucogenys	77.99	0.00e+00	1548.00
IUUC-Opr-070815	Ochotona princeps	76.49	0.00e+00	1481.00
IUUC-Ola-087489	Oryzias latipes	53.79	0.00e+00	1270.00
IUUC-Oga-088449	Otolemur garnettii	89.22	0.00e+00	1740.00
IUUC-Oar-090275	Ovis aries	86.55	0.00e+00	1710.00
IUUC-Ptr-091667	Pan troglodytes	89.14	0.00e+00	1724.00
IUUC-Pan-091723	Papio anubis	88.23	0.00e+00	1446.00
IUUC-Psi-093136	Pelodiscus sinensis	73.05	0.00e+00	1820.00
IUUC-Pab-098755	Pongo abelii	85.96	0.00e+00	1650.00
IUUC-Pca-101134	Procavia capensis	82.67	0.00e+00	1440.00
IUUC-Pva-102433	Pteropus vampyrus	78.29	0.00e+00	1471.00
IUUC-Pgr-103473	Puccinia graminis	30.00	3.00e-38	155.00
IUUC-Ptt-103973	Puccinia triticina	25.36	4.00e-27	118.00
IUUC-Rno-105691	Rattus norvegicus	88.09	0.00e+00	1804.00
IUUC-Sar-112978	Sorex araneus	81.09	0.00e+00	1004.00
IUUC-Sre-115028	Sporisorium reilianum	37.50	1.00e-33	139.00
IUUC-Ssc-115562	Sus scrofa	81.33	0.00e+00	1572.00
IUUC-Tgu-116758	Taeniopygia guttata	82.61	0.00e+00	1662.00
IUUC-Tru-117714	Takifugu rubripes	62.08	0.00e+00	1209.00
IUUC-Tni-119752	Tetraodon nigroviridis	53.81	0.00e+00	1250.00
IUUC-Tbe-127477	Tupaia belangeri	88.17	0.00e+00	710.00
IUUC-Ttr-129196	Tursiops truncatus	84.63	0.00e+00	1662.00
IUUC-Uma-129456	Ustilago maydis	32.30	3.00e-32	135.00
IUUC-Vpa-130035	Vicugna pacos	79.89	0.00e+00	628.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence