iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089382

Ensembl Protein ID

ENSOARP00000009957.1

UniProt Accession

W5PHP0; W5PHP0_SHEEP

Genbank Protein ID

ENSOARP00000009957

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01029095

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009278.1	ENSOART00000010101.1	ENSOARP00000009957.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	80.93	0.00e+00	650.00	IUUC-Hsa-045735

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MAAVAQRGRQ WGESRALGRA VRLLQRLEER CGDPRLSSSP PSLRDLLPRT AQLLHQVAQA 60
RQDASGGVPE GPGGAWDFLV VYLANLEAKS RQVAALLPPP GRKIANDELF REGSRLRRQL 120

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Nucleotide Sequence
(Fasta)

ATGGCTGCGG TGGCCCAGCG GGGACGACAG TGGGGAGAAT CCCGCGCGTT AGGCCGGGCG 60
GTGAGGCTGC TGCAGCGCCT GGAAGAGCGA TGCGGGGACC CCCGGCTCTC CTCGAGTCCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	78.36	0.00e+00	704.00
IUUC-Bta-012705	Bos taurus	93.69	0.00e+00	843.00
IUUC-Cja-019179	Callithrix jacchus	80.09	0.00e+00	680.00
IUUC-Cfa-020593	Canis familiaris	76.01	0.00e+00	689.00
IUUC-Cpo-021289	Cavia porcellus	75.43	5.00e-172	597.00
IUUC-Csa-023966	Chlorocebus sabaeus	72.26	0.00e+00	634.00
IUUC-Dor-030246	Dipodomys ordii	77.05	6.00e-123	434.00
IUUC-Eca-033921	Equus caballus	73.12	1.00e-149	523.00
IUUC-Fca-035747	Felis catus	61.42	1.00e-155	542.00
IUUC-Ggo-044622	Gorilla gorilla	82.69	1.00e-154	538.00
IUUC-Hsa-045735	Homo sapiens	81.46	0.00e+00	681.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	77.16	7.00e-175	606.00
IUUC-Laf-053983	Loxodonta africana	76.80	0.00e+00	727.00
IUUC-Mmr-061310	Microcebus murinus	75.83	0.00e+00	653.00
IUUC-Mmu-064155	Mus musculus	69.54	0.00e+00	657.00
IUUC-Mpu-066655	Mustela putorius furo	72.67	0.00e+00	669.00
IUUC-Mlu-067929	Myotis lucifugus	83.01	3.00e-152	530.00
IUUC-Nle-070065	Nomascus leucogenys	67.87	3.00e-153	534.00
IUUC-Ocu-074049	Oryctolagus cuniculus	67.45	5.00e-126	444.00
IUUC-Oga-087952	Otolemur garnettii	77.52	0.00e+00	674.00
IUUC-Ptr-090579	Pan troglodytes	66.57	6.00e-122	430.00
IUUC-Pan-092075	Papio anubis	80.38	0.00e+00	630.00
IUUC-Pab-098100	Pongo abelii	71.13	2.00e-165	575.00
IUUC-Pca-100830	Procavia capensis	78.57	3.00e-109	388.00
IUUC-Pva-102714	Pteropus vampyrus	77.19	1.00e-168	585.00
IUUC-Rno-105348	Rattus norvegicus	70.74	0.00e+00	662.00
IUUC-Sha-107138	Sarcophilus harrisii	62.73	2.00e-122	431.00
IUUC-Ssc-116424	Sus scrofa	79.44	0.00e+00	769.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence