iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069970

Ensembl Protein ID

ENSNLEP00000019094.1

UniProt Accession

G1S0R2; G1S0R2_NOMLE

Genbank Protein ID

ENSNLEP00000019094

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01108463

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000015741.2	ENSNLET00000020059.2	ENSNLEP00000019094.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.79	0.00e+00	925.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MVDTESPLCP LSPLEAGDLE SPLPEEFLQE MGNIQEISQS IGEDSSGSFG FTEYQYLGSC 60
PGSDGSVITD TLSPASSPSS VTYPVVPGSV DESPSGALNI ECRICGDKAS GYHYGVHACE 120

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Nucleotide Sequence
(Fasta)

TTCAACCCAC AGTTGTCCAA TGGCCTGGGC TTCGTGGGAC CTCCGGGGCT GCACGCCCAC 60
GTCAGCCCCA GCCGCCCTGG CCGACCCCTG CCAGGAAACC AGGGAGGCCC CTCCTCTCCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter

KEGG

nle:100602258

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	93.83	0.00e+00	918.00
IUUC-Apl-003330	Anas platyrhynchos	88.35	0.00e+00	845.00
IUUC-Aca-004598	Anolis carolinensis	85.26	0.00e+00	816.00
IUUC-Acl-008339	Aspergillus clavatus	48.48	7.10e-02	30.40
IUUC-Ame-011508	Astyanax mexicanus	73.40	0.00e+00	695.00
IUUC-Bta-012621	Bos taurus	94.66	0.00e+00	888.00
IUUC-Cja-019688	Callithrix jacchus	97.44	0.00e+00	905.00
IUUC-Cfa-020859	Canis familiaris	94.44	0.00e+00	921.00
IUUC-Cpo-021607	Cavia porcellus	88.68	0.00e+00	833.00
IUUC-Csa-023313	Chlorocebus sabaeus	99.15	0.00e+00	917.00
IUUC-Cho-024741	Choloepus hoffmanni	83.33	0.00e+00	747.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	32.20	2.40e-01	28.10
IUUC-Dre-027446	Danio rerio	72.61	0.00e+00	682.00
IUUC-Dno-029173	Dasypus novemcinctus	92.52	0.00e+00	867.00
IUUC-Dor-030581	Dipodomys ordii	90.58	0.00e+00	812.00
IUUC-Dme-031794	Drosophila melanogaster	34.56	4.00e-56	213.00
IUUC-Ete-032330	Echinops telfairi	90.81	0.00e+00	874.00
IUUC-Eca-033712	Equus caballus	95.09	0.00e+00	878.00
IUUC-Fca-036555	Felis catus	95.11	0.00e+00	924.00
IUUC-Fal-036677	Ficedula albicollis	88.03	0.00e+00	842.00
IUUC-Gmo-039240	Gadus morhua	81.55	0.00e+00	642.00
IUUC-Gga-040473	Gallus gallus	88.89	0.00e+00	850.00
IUUC-Gac-041872	Gasterosteus aculeatus	71.88	0.00e+00	701.00
IUUC-Ggo-045226	Gorilla gorilla	99.79	0.00e+00	926.00
IUUC-Hsa-046893	Homo sapiens	99.79	0.00e+00	926.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	92.74	0.00e+00	868.00
IUUC-Lch-050116	Latimeria chalumnae	79.70	0.00e+00	772.00
IUUC-Loc-052131	Lepisosteus oculatus	83.25	0.00e+00	689.00
IUUC-Laf-054323	Loxodonta africana	94.87	0.00e+00	888.00
IUUC-Mcc-054841	Macaca mulatta	99.36	0.00e+00	919.00
IUUC-Meu-056833	Macropus eugenii	82.91	0.00e+00	755.00
IUUC-Mtr-058471	Medicago truncatula	29.82	1.80e-01	30.00
IUUC-Mga-059995	Meleagris gallopavo	80.08	0.00e+00	752.00
IUUC-Mdo-061954	Monodelphis domestica	88.17	0.00e+00	781.00
IUUC-Mmu-064295	Mus musculus	92.09	0.00e+00	838.00
IUUC-Mpu-066216	Mustela putorius furo	94.87	0.00e+00	924.00
IUUC-Ont-071594	Oreochromis niloticus	72.94	0.00e+00	696.00
IUUC-Oan-073501	Ornithorhynchus anatinus	91.67	0.00e+00	769.00
IUUC-Ocu-074634	Oryctolagus cuniculus	85.69	0.00e+00	839.00
IUUC-Oni-082926	Oryza nivara	29.41	1.20e-02	30.80
IUUC-Ola-086585	Oryzias latipes	79.37	0.00e+00	635.00
IUUC-Oga-088738	Otolemur garnettii	97.01	0.00e+00	894.00
IUUC-Oar-090453	Ovis aries	94.23	0.00e+00	885.00
IUUC-Ptr-091518	Pan troglodytes	99.57	0.00e+00	919.00
IUUC-Pan-092006	Papio anubis	99.57	0.00e+00	919.00
IUUC-Psi-093352	Pelodiscus sinensis	86.65	0.00e+00	838.00
IUUC-Pfo-096060	Poecilia formosa	71.67	0.00e+00	683.00
IUUC-Pab-098602	Pongo abelii	93.04	0.00e+00	824.00
IUUC-Pva-102175	Pteropus vampyrus	89.32	0.00e+00	861.00
IUUC-Rno-105283	Rattus norvegicus	91.88	0.00e+00	840.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	8.00e-03	32.00
IUUC-Sha-106560	Sarcophilus harrisii	92.31	0.00e+00	870.00
IUUC-Smo-109075	Selaginella moellendorffii	30.00	1.20e-01	29.60
IUUC-Ssc-115266	Sus scrofa	94.23	0.00e+00	927.00
IUUC-Tgu-116778	Taeniopygia guttata	88.03	0.00e+00	842.00
IUUC-Tru-118436	Takifugu rubripes	71.67	0.00e+00	691.00
IUUC-Tsy-119642	Tarsius syrichta	83.33	0.00e+00	747.00
IUUC-Tni-119859	Tetraodon nigroviridis	71.67	0.00e+00	686.00
IUUC-Tvi-122624	Trichoderma virens	30.91	8.50e-02	29.60
IUUC-Tbe-127464	Tupaia belangeri	93.38	0.00e+00	909.00
IUUC-Ttr-129307	Tursiops truncatus	90.83	0.00e+00	837.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence