iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107388

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01216725

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000008202.1	ENSSHAT00000009563.1	ENSSHAP00000009480.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.90e-212	706.0	407	894

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+G+      g++t++D d +e+snlnrqFLfr+++++k+K+ +aa+a   
   Q: 407  YDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGIgtgkekGMVTITDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAAATLS 495
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+ ++e+h  ++++ +e i+   F++k d++v+aldn+earr+v+++cl++ +pl++sgt+G++G+++ ii++lte+y++++dpp++
   Q: 496  INPQLKIESHLHKVCPATEMIYsdeFYTKQDIIVTALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEAIIPHLTESYNSHRDPPEE 584
           *********************9******************************************************************* PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl++++s e++eg+++v  ++ s++++n++ ++e+a+ +f+
   Q: 585  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYSSAEEVLQRIQSGESLEGCFQV-IKSLSRRPRNWSHCVELARMKFE 672
           *****************************************************************.8889999**************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ d + k++s fw+                                                         +f++
   Q: 673  KYFNHKALQLLHCFPLDTRLKDGSLFWQspkrppspikfefndplhfsfiqtaaklfatiycipftekdlsvevfsnilskldipEFKP 761
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+ +v  +s++     ++l++++ ++ ++k+++++ +lsfekddds  ++d++taa+nlra++++iep +d+ ++k+
   Q: 762  SNKVVQTDETARKPDHVPVSSEDernavFQLEKAISSSEATKNDLQMVVLSFEKDDDSngHIDFITAASNLRAKMYNIEP-ADRLKTKR 849
           ****************998888899*******************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E+iK++ g +fe+++n+fl++a+
   Q: 850  IAGKIIPAIATSTAAVSGLVALELIKIAGGlPFEAYRNCFLNLAI 894
           *****************************************9886 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MEIDDALYSR QRYVLGDSAM QKMARSHVFL SGMGGLGVEI AKNVVLAGIK ALTIHDTKQC 60
QAWDLGTNFF ICEDDVINRR NRAEAVIHHV AELNPYVHVT SSSVSLDETT DLSFLKQYQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGAAACATA CATTCCCCCC ACATGGCAGG TGACTCAATG GAGATCGATG ATGCTTTATA 60
CAGGTAAGAG TCCATAGAAA GCCACAGTTT GGAAGTTGTA TTTCGGTATT TTGTTATTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	87.01	0.00e+00	1880.00
IUUC-Apl-004158	Anas platyrhynchos	82.43	0.00e+00	1735.00
IUUC-Aca-005349	Anolis carolinensis	81.42	0.00e+00	1771.00
IUUC-Bta-012696	Bos taurus	86.81	0.00e+00	1875.00
IUUC-Cja-019563	Callithrix jacchus	86.42	0.00e+00	1848.00
IUUC-Cfa-020951	Canis familiaris	87.30	0.00e+00	1889.00
IUUC-Cpo-022307	Cavia porcellus	83.66	0.00e+00	1808.00
IUUC-Csa-023647	Chlorocebus sabaeus	86.22	0.00e+00	1854.00
IUUC-Cho-024682	Choloepus hoffmanni	73.36	0.00e+00	892.00
IUUC-Dre-028022	Danio rerio	68.50	0.00e+00	1482.00
IUUC-Dno-029796	Dasypus novemcinctus	87.40	0.00e+00	1860.00
IUUC-Dor-030981	Dipodomys ordii	71.20	0.00e+00	1436.00
IUUC-Ete-032514	Echinops telfairi	74.04	0.00e+00	1089.00
IUUC-Eca-033697	Equus caballus	86.91	0.00e+00	1886.00
IUUC-Eeu-035323	Erinaceus europaeus	81.03	0.00e+00	1258.00
IUUC-Fca-035858	Felis catus	86.71	0.00e+00	1881.00
IUUC-Fal-036848	Ficedula albicollis	81.71	0.00e+00	1741.00
IUUC-Gmo-039326	Gadus morhua	66.63	0.00e+00	1389.00
IUUC-Gga-040747	Gallus gallus	82.01	0.00e+00	1734.00
IUUC-Gac-041406	Gasterosteus aculeatus	67.55	0.00e+00	1378.00
IUUC-Ggo-044577	Gorilla gorilla	86.04	0.00e+00	1852.00
IUUC-Hsa-046007	Homo sapiens	86.02	0.00e+00	1846.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	88.20	0.00e+00	1001.00
IUUC-Lch-049992	Latimeria chalumnae	75.02	0.00e+00	1562.00
IUUC-Loc-051899	Lepisosteus oculatus	70.56	0.00e+00	1509.00
IUUC-Laf-054413	Loxodonta africana	87.41	0.00e+00	1794.00
IUUC-Mcc-054656	Macaca mulatta	86.32	0.00e+00	1851.00
IUUC-Meu-056463	Macropus eugenii	79.98	0.00e+00	1556.00
IUUC-Mga-059721	Meleagris gallopavo	80.86	0.00e+00	1632.00
IUUC-Mmr-060908	Microcebus murinus	83.37	0.00e+00	1794.00
IUUC-Mdo-062096	Monodelphis domestica	95.38	0.00e+00	2034.00
IUUC-Mmu-064114	Mus musculus	85.93	0.00e+00	1857.00
IUUC-Mpu-066017	Mustela putorius furo	86.81	0.00e+00	1882.00
IUUC-Mlu-068037	Myotis lucifugus	84.74	0.00e+00	1793.00
IUUC-Nle-069494	Nomascus leucogenys	86.12	0.00e+00	1844.00
IUUC-Opr-070910	Ochotona princeps	62.06	9.00e-160	557.00
IUUC-Ont-071592	Oreochromis niloticus	69.35	0.00e+00	1453.00
IUUC-Oan-073268	Ornithorhynchus anatinus	82.36	0.00e+00	1611.00
IUUC-Ocu-074296	Oryctolagus cuniculus	87.11	0.00e+00	1887.00
IUUC-Ola-086376	Oryzias latipes	68.96	0.00e+00	1394.00
IUUC-Oga-088186	Otolemur garnettii	86.49	0.00e+00	1855.00
IUUC-Oar-089307	Ovis aries	87.30	0.00e+00	1887.00
IUUC-Ptr-090609	Pan troglodytes	86.32	0.00e+00	1848.00
IUUC-Pan-092905	Papio anubis	86.05	0.00e+00	1766.00
IUUC-Psi-093489	Pelodiscus sinensis	83.19	0.00e+00	1773.00
IUUC-Pma-094203	Petromyzon marinus	64.63	3.00e-55	206.00
IUUC-Pfo-096670	Poecilia formosa	68.80	0.00e+00	1449.00
IUUC-Pab-098418	Pongo abelii	86.32	0.00e+00	1845.00
IUUC-Pca-100889	Procavia capensis	73.13	0.00e+00	1512.00
IUUC-Pva-103144	Pteropus vampyrus	75.59	0.00e+00	1592.00
IUUC-Rno-105612	Rattus norvegicus	85.83	0.00e+00	1854.00
IUUC-Sar-113128	Sorex araneus	84.35	0.00e+00	1831.00
IUUC-Ssc-116117	Sus scrofa	87.30	0.00e+00	1889.00
IUUC-Tgu-116565	Taeniopygia guttata	82.20	0.00e+00	1755.00
IUUC-Tru-118591	Takifugu rubripes	67.55	0.00e+00	1406.00
IUUC-Tsy-119436	Tarsius syrichta	77.06	0.00e+00	1603.00
IUUC-Tni-120880	Tetraodon nigroviridis	67.03	0.00e+00	1394.00
IUUC-Tbe-127714	Tupaia belangeri	74.02	0.00e+00	1318.00
IUUC-Ttr-129159	Tursiops truncatus	84.28	0.00e+00	1574.00
IUUC-Vpa-130716	Vicugna pacos	84.71	0.00e+00	1796.00
IUUC-Xtr-132947	Xenopus tropicalis	70.95	0.00e+00	1529.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence