iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069421

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01171665

Gene Name

UBE2E2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000003554.1	ENSNLET00000004514.1	ENSNLEP00000004290.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.60e-50	169.8	59	194

Active Site

Position(s)	Description	Evidence
139	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel+e++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f++dYPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 59   RIQKELAEITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 144
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 145  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 194
           *********************************************99985 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MSTEAQRVDD SPSTSGGSSD GDQRESVQQE PEREQVQPKK KEGKISSKTA AKLSTSAKRI 60
QKELAEITLD PPPNCSAGPK GDNIYEWRST ILGPPGSVYE GGVFFLDITF SPDYPFKPPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCACTG AGGCACAAAG AGTTGATGAC AGTCCAAGCA CTAGTGGAGG AAGTTCCGAT 60
GGAGATCAAC GTGAAAGTGT TCAGCAAGAA CCAGAAAGAG AACAAGTTCA GCCCAAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0032020--P:ISG15-protein conjugation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

KEGG

nle:100589888

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005044	Anolis carolinensis	98.01	1.00e-97	348.00
IUUC-Ame-011419	Astyanax mexicanus	95.80	1.00e-82	298.00
IUUC-Cre-022791	Chlamydomonas reinhardtii	80.13	1.00e-71	261.00
IUUC-Cho-024986	Choloepus hoffmanni	89.55	8.00e-87	312.00
IUUC-Dno-029130	Dasypus novemcinctus	100.00	1.00e-74	271.00
IUUC-Dme-032042	Drosophila melanogaster	87.65	2.00e-84	305.00
IUUC-Fca-035425	Felis catus	99.50	2.00e-85	307.00
IUUC-Fal-037043	Ficedula albicollis	98.51	2.00e-85	308.00
IUUC-Gmo-039645	Gadus morhua	91.13	6.00e-92	329.00
IUUC-Gga-040236	Gallus gallus	100.00	3.00e-85	306.00
IUUC-Gac-041661	Gasterosteus aculeatus	91.54	3.00e-91	327.00
IUUC-Hsa-046767	Homo sapiens	100.00	5.00e-86	309.00
IUUC-Loc-052673	Lepisosteus oculatus	94.53	2.00e-94	337.00
IUUC-Mcc-055072	Macaca mulatta	100.00	5.00e-86	309.00
IUUC-Mmr-060629	Microcebus murinus	100.00	5.00e-86	309.00
IUUC-Mmu-063733	Mus musculus	99.50	2.00e-99	354.00
IUUC-Mlu-067897	Myotis lucifugus	99.50	5.00e-86	309.00
IUUC-Ont-071325	Oreochromis niloticus	92.04	4.00e-92	330.00
IUUC-Oan-073704	Ornithorhynchus anatinus	100.00	1.00e-74	270.00
IUUC-Pab-098017	Pongo abelii	100.00	5.00e-86	309.00
IUUC-Pva-102561	Pteropus vampyrus	99.50	5.00e-86	309.00
IUUC-Tru-118527	Takifugu rubripes	95.77	1.00e-81	295.00
IUUC-Ttr-128358	Tursiops truncatus	100.00	5.00e-86	309.00
IUUC-Vpa-130232	Vicugna pacos	98.58	5.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence