iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004101

Ensembl Protein ID

ENSAPLP00000004488.1

UniProt Accession

U3IB66; U3IB66_ANAPL

Genbank Protein ID

ENSAPLP00000004488

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01023520

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004947.1	ENSAPLT00000005104.1	ENSAPLP00000004488.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.70e-09	35.9	13	66

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw............pglknssskefrC 42
           C+iCl+ f++ p+++pCgH f+a+Cl   w            pg++++ +++ +C
   Q: 13   CSICLSLFDT-PVTVPCGHNFCASCLdLTWaeldagfxrttfPGRPQLRKNTVLC 66
           ********99.9**************99999999999999999999999999988 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

EPNLAGLEED LTCSICLSLF DTPVTVPCGH NFCASCLDLT WAELDAGFXR TTFPGRPQLR 60
KNTVLCRVVE QLQGCTAAAS PVYCDSCLQA HAAQTCLTCM ASFCAEHLQP HHDSPAFRDH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCCGAACC TGGCGGGGCT GGAGGAGGAT CTGACCTGCT CCATCTGCCT CTCCCTCTTC 60
GACACCCCCG TGACGGTGCC GTGCGGCCAC AACTTCTGCG CCTCCTGCCT GGACCTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	49.92	2.00e-178	618.00
IUUC-Aca-005025	Anolis carolinensis	52.58	0.00e+00	653.00
IUUC-Ame-011848	Astyanax mexicanus	25.77	2.00e-51	196.00
IUUC-Bta-012735	Bos taurus	48.68	1.00e-178	619.00
IUUC-Cja-019996	Callithrix jacchus	45.13	2.00e-85	309.00
IUUC-Cfa-020466	Canis familiaris	50.08	2.00e-177	615.00
IUUC-Cpo-021737	Cavia porcellus	46.15	2.00e-164	571.00
IUUC-Csa-023217	Chlorocebus sabaeus	48.49	5.00e-174	603.00
IUUC-Cho-024346	Choloepus hoffmanni	35.99	4.00e-39	154.00
IUUC-Dre-028680	Danio rerio	33.23	1.00e-34	139.00
IUUC-Dno-030082	Dasypus novemcinctus	49.45	3.00e-178	618.00
IUUC-Dor-030335	Dipodomys ordii	37.58	4.00e-73	268.00
IUUC-Ete-032923	Echinops telfairi	46.06	3.00e-147	514.00
IUUC-Eca-033411	Equus caballus	50.00	9.00e-177	613.00
IUUC-Eeu-034656	Erinaceus europaeus	45.40	2.00e-84	306.00
IUUC-Fca-035371	Felis catus	49.22	1.00e-175	609.00
IUUC-Fal-037008	Ficedula albicollis	65.59	0.00e+00	810.00
IUUC-Gmo-038668	Gadus morhua	34.31	7.00e-104	370.00
IUUC-Gga-040608	Gallus gallus	70.56	0.00e+00	825.00
IUUC-Gac-041409	Gasterosteus aculeatus	36.48	2.00e-113	402.00
IUUC-Ggo-044518	Gorilla gorilla	48.63	2.00e-169	588.00
IUUC-Hsa-045828	Homo sapiens	48.24	4.00e-170	590.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	46.19	2.00e-158	551.00
IUUC-Lch-050490	Latimeria chalumnae	29.70	2.00e-73	269.00
IUUC-Loc-052864	Lepisosteus oculatus	37.83	3.00e-119	421.00
IUUC-Laf-054325	Loxodonta africana	48.47	3.00e-95	341.00
IUUC-Mcc-054920	Macaca mulatta	48.56	5.00e-172	597.00
IUUC-Meu-056367	Macropus eugenii	64.94	5.00e-68	251.00
IUUC-Mga-059975	Meleagris gallopavo	71.27	0.00e+00	823.00
IUUC-Mmr-060748	Microcebus murinus	48.41	4.00e-169	587.00
IUUC-Mdo-062904	Monodelphis domestica	48.84	6.00e-163	567.00
IUUC-Mmu-063891	Mus musculus	48.49	5.00e-174	603.00
IUUC-Mpu-066473	Mustela putorius furo	49.14	3.00e-178	617.00
IUUC-Mlu-068185	Myotis lucifugus	49.01	2.00e-92	333.00
IUUC-Nle-070177	Nomascus leucogenys	48.88	5.00e-172	597.00
IUUC-Opr-070558	Ochotona princeps	43.54	2.00e-83	302.00
IUUC-Ont-072074	Oreochromis niloticus	33.18	2.00e-98	352.00
IUUC-Oan-072819	Ornithorhynchus anatinus	33.91	2.00e-23	102.00
IUUC-Ocu-074461	Oryctolagus cuniculus	50.00	4.00e-92	332.00
IUUC-Ola-086993	Oryzias latipes	25.65	1.00e-54	207.00
IUUC-Oga-088937	Otolemur garnettii	45.73	6.00e-157	547.00
IUUC-Oar-089781	Ovis aries	46.98	2.00e-119	422.00
IUUC-Ptr-090771	Pan troglodytes	46.89	5.00e-89	321.00
IUUC-Pan-092830	Papio anubis	48.56	1.00e-171	596.00
IUUC-Psi-093664	Pelodiscus sinensis	62.78	0.00e+00	748.00
IUUC-Pma-094147	Petromyzon marinus	27.26	1.00e-49	190.00
IUUC-Pfo-096528	Poecilia formosa	36.36	4.00e-61	228.00
IUUC-Pab-097588	Pongo abelii	48.88	1.00e-170	592.00
IUUC-Pca-100890	Procavia capensis	49.30	9.00e-90	323.00
IUUC-Pva-102314	Pteropus vampyrus	51.11	6.00e-167	580.00
IUUC-Rno-105234	Rattus norvegicus	47.49	6.00e-87	314.00
IUUC-Sha-106807	Sarcophilus harrisii	46.22	6.00e-83	301.00
IUUC-Sar-113283	Sorex araneus	43.84	1.00e-70	259.00
IUUC-Ssc-115878	Sus scrofa	50.00	9.00e-58	216.00
IUUC-Tgu-117026	Taeniopygia guttata	63.55	0.00e+00	651.00
IUUC-Tru-117794	Takifugu rubripes	51.11	5.00e-51	195.00
IUUC-Tsy-119001	Tarsius syrichta	32.18	2.00e-20	93.60
IUUC-Tni-120785	Tetraodon nigroviridis	24.72	1.00e-40	160.00
IUUC-Tbe-127580	Tupaia belangeri	44.06	2.00e-77	282.00
IUUC-Ttr-128648	Tursiops truncatus	64.89	2.00e-81	296.00
IUUC-Vpa-130254	Vicugna pacos	68.79	1.00e-76	280.00
IUUC-Xtr-132892	Xenopus tropicalis	43.52	3.00e-78	284.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence