iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fox-037774

Ensembl Protein ID

FOXG_05190P0

UniProt Accession

A0A0D2XML3; A0A0D2XML3_FUSO4

Genbank Protein ID

KNB02195.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

DS231700

Gene Name

FOXG_05190

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FOXG_05190	FOXG_05190T0	FOXG_05190P0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.90e-125	416.1	477	809

Active Site

Position(s)	Description	Evidence
778	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyk 98
           + dlkkrl+++f gE+gld+gG++ref++lls+e++np ++lf+ys+ d++tlq+np+sg+ npehl++F+f+Gr++g+a++++r+ld+++  ++yk
   Q: 477  ATDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGI-NPEHLNYFKFIGRVVGLAIFHRRFLDAFFIGALYK 572
           579*********************************************************9.89********************************* PP
   S: 99   lllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafre 195
           ++lgk + l d+e vd+++++sl+++++n   di+   l+ tfs+++e +g +++e+L+p+G+ni+VtneNk+eYv+l+v++r++++i+eq++af+e
   Q: 573  MMLGKAVALADMEGVDADFHRSLQWMLDN---DISGGILEQTFSTEDERFGVMTTEDLIPDGRNIDVTNENKKEYVDLMVKWRIEKRIAEQFQAFKE 666
           ***************************99...9**************************************************************** PP
   S: 196  GfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfv 288
           Gf+e+ip++l+++F+e+elelli G +eidv+d+kk+t y+g yte+++++q+Fw ++++++ e+++++LqF+Tg+sr+P++Gf++l+    pr+f+
   Q: 667  GFQELIPQDLINVFDERELELLIGGIAEIDVDDWKKHTDYRG-YTESDEVVQNFWATVRSWDGEQKSRLLQFTTGTSRIPVNGFKDLQgsdgPRRFT 762
           ****************************************76.****************************************************** PP
   S: 289  irkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           i+k+++ ++lP+++TCfn+L+LP+Y+s e l++kL++A+eet gF++
   Q: 763  IEKAGEITNLPKAHTCFNRLDLPPYKSLEMLQQKLTIAVEETMGFGQ 809
           ***9999**************************************96 PP

Organism

Fusarium oxysporum

Protein Sequence
(Fasta)

MTSRTDSNRP NLRVTIIAAD GLYKRDVFRF PDPFAVATIN GEQTKTTTVS KRTLNPYWNE 60
SFDFRTNEDG ILAVQVFDQK KFKKKDQGFL GVINIRVGDV IPELSPDADD QMLTRDLKKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCAGTGAA CCCTTCAACC TCCACTGATC ACGTTCCGCG AGCGCCTTCC ACGACAAGGC 60
TTCATTGCAT TTGTCTGGCT CCGAACCTAT TTCTACTTTT CACCTCAGAA ATATCGATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR024928--E3_ub_ligase_SMURF1
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	46.63	7.00e-153	532.00
IUUC-Apl-003893	Anas platyrhynchos	43.38	1.00e-150	525.00
IUUC-Aca-005338	Anolis carolinensis	47.20	4.00e-155	540.00
IUUC-Ago-007742	Ashbya gossypii	64.76	0.00e+00	1012.00
IUUC-Acl-008273	Aspergillus clavatus	72.88	0.00e+00	1130.00
IUUC-Afl-008713	Aspergillus flavus	72.71	0.00e+00	1129.00
IUUC-Afu-009103	Aspergillus fumigatus	70.42	0.00e+00	1100.00
IUUC-Ani-009259	Aspergillus nidulans	72.12	0.00e+00	1133.00
IUUC-Ang-009738	Aspergillus niger	72.65	0.00e+00	1144.00
IUUC-Aor-010053	Aspergillus oryzae	78.67	2.00e-144	503.00
IUUC-Ate-010529	Aspergillus terreus	73.57	0.00e+00	1136.00
IUUC-Ame-011081	Astyanax mexicanus	47.51	3.00e-155	540.00
IUUC-Bgr-012148	Blumeria graminis	76.11	0.00e+00	1177.00
IUUC-Bta-012679	Bos taurus	46.63	4.00e-153	533.00
IUUC-Bci-013785	Botrytis cinerea	78.67	0.00e+00	1239.00
IUUC-Cel-018299	Caenorhabditis elegans	44.12	1.00e-142	498.00
IUUC-Cja-018732	Callithrix jacchus	46.47	2.00e-152	531.00
IUUC-Cfa-021226	Canis familiaris	46.63	6.00e-153	533.00
IUUC-Cpo-021671	Cavia porcellus	46.63	7.00e-153	533.00
IUUC-Csa-023344	Chlorocebus sabaeus	45.14	5.00e-149	520.00
IUUC-Cho-024695	Choloepus hoffmanni	44.28	5.00e-158	550.00
IUUC-Cin-025212	Ciona intestinalis	45.62	7.00e-148	516.00
IUUC-Csv-026256	Ciona savignyi	46.05	2.00e-147	513.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	87.64	0.00e+00	1394.00
IUUC-Cne-026849	Cryptococcus neoformans	61.04	0.00e+00	978.00
IUUC-Dre-027770	Danio rerio	50.82	1.00e-139	489.00
IUUC-Dno-029466	Dasypus novemcinctus	46.63	4.00e-153	533.00
IUUC-Dor-030138	Dipodomys ordii	45.98	5.00e-148	516.00
IUUC-Dse-031241	Dothistroma septosporum	72.22	0.00e+00	1157.00
IUUC-Dme-032041	Drosophila melanogaster	44.88	3.00e-139	487.00
IUUC-Ete-032779	Echinops telfairi	43.20	2.00e-136	478.00
IUUC-Eca-033445	Equus caballus	46.63	7.00e-153	532.00
IUUC-Eeu-035247	Erinaceus europaeus	46.78	4.00e-152	530.00
IUUC-Fca-036384	Felis catus	47.97	3.00e-158	551.00
IUUC-Fal-037126	Ficedula albicollis	47.38	4.00e-156	543.00
IUUC-Fso-038393	Fusarium solani	95.33	0.00e+00	1447.00
IUUC-Gmo-039674	Gadus morhua	43.22	8.00e-146	509.00
IUUC-Ggr-040107	Gaeumannomyces graminis	85.38	0.00e+00	1351.00
IUUC-Gga-041276	Gallus gallus	45.81	1.00e-149	522.00
IUUC-Gac-042020	Gasterosteus aculeatus	46.66	7.00e-147	513.00
IUUC-Ggo-045332	Gorilla gorilla	46.63	9.00e-153	532.00
IUUC-Hsa-045968	Homo sapiens	46.63	7.00e-153	533.00
IUUC-Itr-048918	Ictidomys tridecemlineatus	45.34	2.00e-156	544.00
IUUC-Kpa-049273	Komagataella pastoris	66.33	0.00e+00	1036.00
IUUC-Lch-050443	Latimeria chalumnae	46.14	1.00e-151	528.00
IUUC-Loc-052645	Lepisosteus oculatus	47.87	4.00e-152	530.00
IUUC-Lma-052980	Leptosphaeria maculans	70.78	0.00e+00	679.00
IUUC-Laf-053850	Loxodonta africana	46.63	9.00e-153	532.00
IUUC-Mcc-055821	Macaca mulatta	46.63	7.00e-153	532.00
IUUC-Meu-055953	Macropus eugenii	40.37	2.00e-117	415.00
IUUC-Mor-057097	Magnaporthe oryzae	86.78	0.00e+00	1400.00
IUUC-Mpo-057442	Magnaporthe poae	81.25	0.00e+00	1222.00
IUUC-Mla-058996	Melampsora laricipopulina	62.28	0.00e+00	991.00
IUUC-Mga-059362	Meleagris gallopavo	46.50	3.00e-150	524.00
IUUC-Mvi-060395	Microbotryum violaceum	78.05	0.00e+00	807.00
IUUC-Mmr-061061	Microcebus murinus	45.41	4.00e-158	550.00
IUUC-Mdo-062173	Monodelphis domestica	44.90	1.00e-148	519.00
IUUC-Mmu-064136	Mus musculus	46.63	3.00e-153	534.00
IUUC-Mpu-066765	Mustela putorius furo	46.63	1.00e-152	532.00
IUUC-Mlu-067565	Myotis lucifugus	46.63	1.00e-152	531.00
IUUC-Nfi-068427	Neosartorya fischeri	72.85	0.00e+00	1123.00
IUUC-Ncr-068918	Neurospora crassa	80.83	0.00e+00	1263.00
IUUC-Nle-069225	Nomascus leucogenys	46.83	8.00e-155	539.00
IUUC-Opr-071044	Ochotona princeps	46.78	4.00e-152	530.00
IUUC-Ont-071664	Oreochromis niloticus	47.29	4.00e-144	503.00
IUUC-Oan-073019	Ornithorhynchus anatinus	45.81	2.00e-149	521.00
IUUC-Ocu-074160	Oryctolagus cuniculus	46.70	5.00e-152	530.00
IUUC-Ola-087467	Oryzias latipes	45.03	9.00e-148	516.00
IUUC-Oga-088460	Otolemur garnettii	46.63	8.00e-153	532.00
IUUC-Oar-090198	Ovis aries	45.28	7.00e-153	533.00
IUUC-Ptr-090939	Pan troglodytes	46.63	7.00e-153	533.00
IUUC-Pan-092284	Papio anubis	46.63	6.00e-153	533.00
IUUC-Psi-093645	Pelodiscus sinensis	46.13	2.00e-152	531.00
IUUC-Pma-094364	Petromyzon marinus	50.00	2.00e-140	490.00
IUUC-Pno-095118	Phaeosphaeria nodorum	71.33	0.00e+00	1145.00
IUUC-Pfo-097145	Poecilia formosa	47.01	1.00e-147	515.00
IUUC-Pab-098088	Pongo abelii	46.63	6.00e-153	533.00
IUUC-Pca-100596	Procavia capensis	43.64	3.00e-142	497.00
IUUC-Pva-102354	Pteropus vampyrus	46.47	3.00e-152	530.00
IUUC-Pgr-103620	Puccinia graminis	67.20	0.00e+00	843.00
IUUC-Ptt-103806	Puccinia triticina	76.57	0.00e+00	679.00
IUUC-Pte-104016	Pyrenophora teres	72.59	0.00e+00	1155.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	72.59	0.00e+00	1155.00
IUUC-Rno-105318	Rattus norvegicus	46.63	2.00e-153	534.00
IUUC-Sce-106289	Saccharomyces cerevisiae	64.58	0.00e+00	1013.00
IUUC-Sha-107482	Sarcophilus harrisii	46.28	4.00e-150	523.00
IUUC-Sja-107941	Schizosaccharomyces japonicus	64.97	0.00e+00	1024.00
IUUC-Spo-108171	Schizosaccharomyces pombe	65.09	0.00e+00	1026.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	78.74	0.00e+00	1237.00
IUUC-Sar-113761	Sorex araneus	47.34	2.00e-155	540.00
IUUC-Sre-114929	Sporisorium reilianum	70.73	0.00e+00	874.00
IUUC-Ssc-115368	Sus scrofa	44.71	9.00e-148	515.00
IUUC-Tgu-117130	Taeniopygia guttata	44.74	7.00e-151	526.00
IUUC-Tru-118610	Takifugu rubripes	52.06	3.00e-145	507.00
IUUC-Tsy-119492	Tarsius syrichta	47.49	2.00e-151	528.00
IUUC-Tni-119993	Tetraodon nigroviridis	45.97	1.00e-148	518.00
IUUC-Tre-122203	Trichoderma reesei	85.34	0.00e+00	1337.00
IUUC-Tvi-122595	Trichoderma virens	85.32	0.00e+00	1370.00
IUUC-Tme-126897	Tuber melanosporum	70.04	0.00e+00	1056.00
IUUC-Tbe-127793	Tupaia belangeri	47.12	8.00e-129	452.00
IUUC-Ttr-128275	Tursiops truncatus	45.50	4.00e-147	513.00
IUUC-Uma-129332	Ustilago maydis	70.56	0.00e+00	849.00
IUUC-Vda-129753	Verticillium dahliae	83.79	0.00e+00	1298.00
IUUC-Vpa-130503	Vicugna pacos	51.03	4.00e-136	477.00
IUUC-Xtr-132859	Xenopus tropicalis	46.49	3.00e-152	530.00
IUUC-Xma-133797	Xiphophorus maculatus	46.85	7.00e-150	523.00
IUUC-Yli-134668	Yarrowia lipolytica	73.35	0.00e+00	934.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence