iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036525

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02139567

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000008347.3	ENSFCAT00000008349.3	ENSFCAP00000007739.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.40e-71	240.7	69	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ +++++++ p++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 69   GLVNLGNTCFMNSLLQGLSACPAFIKWLEEFTTQYTRDQKEPPPHQYLSLTLLHLLKALScqeVTDDEVLDASCLLDVLRMYRWQISSF 157
           9*****************************88888888888999***************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e++ e          + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 158  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQPEitpkqitcrtRGSPHPTSNHWKSQHPFHGRLTSNMICKHCEHQSpVR 244
           *******************9..678889999999988888888999999999999********************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 245  FDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTqieakgtldgekvehQRTTFVKQLKLGKLPQCLCIHLQRLSW 330
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts............................................................. 267
           s++ + + k +++v+f++ L ++ +  +                                                             
   Q: 331  SSH-GTPLKRHEHVQFNEFLMMDIYKYHllghrpgqhspkpgesagpsldlqdgpaaprsvlnqpggpktqifmngacspsllptlpap 418
           998.8888*********888888666666678877777777777777776666666666666666665555555555555555555555 PP
   S: 268  ........peekqke....kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
                   p     +    ++ ++L+avvvH+G ++sGH+v+y ++         ++++Wl ++D++V++ + +evl+   s+aY+lfY
   Q: 419  mpfplpvvP-----DysssTYLFRLMAVVVHHGDMHSGHFVTYRRSppsaknplsTSNQWLWISDDTVRKASLQEVLS---SSAYLLFY 499
           555555553.....055549999***********************9999888888999*******************...******** PP
   S: 336  kr 337
           +r
   Q: 500  ER 501
           98 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MLSSRAQAAM TAADRAIQRF LRTGAAVRYK VMKNWGVIGG LAAALAAGIY VIWGPITERK 60
KRRKGLVPGL VNLGNTCFMN SLLQGLSACP AFIKWLEEFT TQYTRDQKEP PPHQYLSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTACAAGCT ACTTGTAAGC ATCGTGGGTC TCCTGGGATG TGAAGTGTGG GTCATGATAC 60
GGGTGCTGTG AAGGCTGAAA GTAATGCATG TGACGTACTC AGCAATGCAC GCAAGTACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fca:101087177

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	29.04	7.00e-16	78.60
IUUC-Aml-001733	Ailuropoda melanoleuca	96.54	0.00e+00	909.00
IUUC-Atr-002510	Amborella trichopoda	25.24	6.00e-22	99.00
IUUC-Apl-003645	Anas platyrhynchos	72.92	3.00e-108	384.00
IUUC-Aca-004583	Anolis carolinensis	68.42	2.00e-24	103.00
IUUC-Aly-005754	Arabidopsis lyrata	27.47	1.00e-23	104.00
IUUC-Ath-007622	Arabidopsis thaliana	27.35	2.00e-24	107.00
IUUC-Acl-008136	Aspergillus clavatus	22.22	6.00e-14	72.80
IUUC-Ani-009286	Aspergillus nidulans	20.59	1.00e-10	61.60
IUUC-Ame-010896	Astyanax mexicanus	61.18	2.00e-154	538.00
IUUC-Bta-012321	Bos taurus	93.04	0.00e+00	877.00
IUUC-Bdi-014795	Brachypodium distachyon	28.30	8.00e-18	84.70
IUUC-Bol-015637	Brassica oleracea	27.25	7.00e-25	108.00
IUUC-Bra-016801	Brassica rapa	25.47	3.00e-24	106.00
IUUC-Cel-018308	Caenorhabditis elegans	27.91	1.00e-36	147.00
IUUC-Cja-018826	Callithrix jacchus	94.21	0.00e+00	935.00
IUUC-Cfa-021206	Canis familiaris	94.42	0.00e+00	915.00
IUUC-Cpo-021343	Cavia porcellus	91.62	0.00e+00	852.00
IUUC-Csa-023419	Chlorocebus sabaeus	93.81	0.00e+00	932.00
IUUC-Cho-024475	Choloepus hoffmanni	89.45	6.00e-139	487.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.93	3.00e-13	70.50
IUUC-Cne-027061	Cryptococcus neoformans	25.00	1.00e-09	58.50
IUUC-Dre-027563	Danio rerio	58.18	2.00e-156	545.00
IUUC-Dno-029929	Dasypus novemcinctus	93.04	0.00e+00	910.00
IUUC-Dor-030166	Dipodomys ordii	83.17	0.00e+00	756.00
IUUC-Dme-031627	Drosophila melanogaster	33.79	3.00e-35	143.00
IUUC-Ete-032634	Echinops telfairi	80.46	0.00e+00	692.00
IUUC-Eca-033968	Equus caballus	93.27	0.00e+00	847.00
IUUC-Eeu-035279	Erinaceus europaeus	81.71	3.00e-59	222.00
IUUC-Fal-036606	Ficedula albicollis	74.74	4.00e-161	560.00
IUUC-Fso-038309	Fusarium solani	20.89	4.00e-09	56.60
IUUC-Gmo-038726	Gadus morhua	55.23	6.00e-142	497.00
IUUC-Gga-040718	Gallus gallus	75.19	6.00e-163	566.00
IUUC-Gac-042645	Gasterosteus aculeatus	56.85	3.00e-150	525.00
IUUC-Gma-042890	Glycine max	25.52	5.00e-26	112.00
IUUC-Ggo-045021	Gorilla gorilla	93.81	0.00e+00	930.00
IUUC-Hsa-045832	Homo sapiens	93.81	0.00e+00	930.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	94.29	0.00e+00	861.00
IUUC-Lch-050662	Latimeria chalumnae	70.13	2.00e-180	624.00
IUUC-Lpe-051078	Leersia perrieri	26.31	4.00e-31	129.00
IUUC-Loc-052611	Lepisosteus oculatus	64.85	3.00e-178	617.00
IUUC-Lma-053048	Leptosphaeria maculans	20.16	1.00e-15	78.20
IUUC-Laf-053752	Loxodonta africana	92.24	0.00e+00	842.00
IUUC-Mcc-054892	Macaca mulatta	94.20	0.00e+00	935.00
IUUC-Meu-056673	Macropus eugenii	75.00	5.00e-165	573.00
IUUC-Mor-057143	Magnaporthe oryzae	21.41	7.00e-09	56.20
IUUC-Mtr-057976	Medicago truncatula	26.41	7.00e-33	135.00
IUUC-Mla-058970	Melampsora laricipopulina	22.59	7.00e-20	92.00
IUUC-Mga-059543	Meleagris gallopavo	76.60	0.00e+00	672.00
IUUC-Mmr-061534	Microcebus murinus	93.23	0.00e+00	895.00
IUUC-Mdo-062140	Monodelphis domestica	68.04	1.00e-168	586.00
IUUC-Mmu-063673	Mus musculus	89.56	0.00e+00	844.00
IUUC-Mpu-066328	Mustela putorius furo	95.55	0.00e+00	895.00
IUUC-Mlu-067938	Myotis lucifugus	95.55	0.00e+00	940.00
IUUC-Nfi-068306	Neosartorya fischeri	21.76	8.00e-14	72.00
IUUC-Nle-069426	Nomascus leucogenys	92.76	0.00e+00	830.00
IUUC-Opr-070796	Ochotona princeps	85.60	2.00e-124	439.00
IUUC-Ont-072248	Oreochromis niloticus	59.73	1.00e-157	549.00
IUUC-Oan-072916	Ornithorhynchus anatinus	79.92	0.00e+00	777.00
IUUC-Ocu-074459	Oryctolagus cuniculus	86.67	0.00e+00	665.00
IUUC-Oba-075765	Oryza barthii	25.74	6.00e-29	122.00
IUUC-Obr-076005	Oryza brachyantha	26.77	3.00e-31	129.00
IUUC-Ogl-077916	Oryza glaberrima	26.49	2.00e-32	133.00
IUUC-Ogu-078263	Oryza glumaepatula	26.11	1.00e-29	124.00
IUUC-Oin-080096	Oryza indica	26.19	3.00e-23	103.00
IUUC-Ome-081928	Oryza meridionalis	26.31	1.00e-30	127.00
IUUC-Oni-082424	Oryza nivara	25.97	1.00e-29	124.00
IUUC-Oru-085117	Oryza rufipogon	25.97	1.00e-29	124.00
IUUC-Ola-087429	Oryzias latipes	56.21	5.00e-149	520.00
IUUC-Oga-087981	Otolemur garnettii	93.04	0.00e+00	886.00
IUUC-Oar-089927	Ovis aries	92.26	0.00e+00	869.00
IUUC-Ptr-090878	Pan troglodytes	93.81	0.00e+00	930.00
IUUC-Pan-092698	Papio anubis	94.20	0.00e+00	935.00
IUUC-Psi-093451	Pelodiscus sinensis	76.52	0.00e+00	718.00
IUUC-Pfo-096096	Poecilia formosa	59.40	4.00e-156	544.00
IUUC-Pab-098676	Pongo abelii	92.65	0.00e+00	910.00
IUUC-Pca-100418	Procavia capensis	95.40	2.00e-130	459.00
IUUC-Ppe-101898	Prunus persica	25.38	1.00e-25	110.00
IUUC-Pva-103018	Pteropus vampyrus	92.26	0.00e+00	890.00
IUUC-Pgr-103423	Puccinia graminis	24.23	9.00e-10	59.30
IUUC-Pte-104330	Pyrenophora teres	22.35	1.00e-14	75.10
IUUC-Pyt-104518	Pyrenophora triticirepentis	22.75	2.00e-17	84.00
IUUC-Rno-105708	Rattus norvegicus	88.97	0.00e+00	838.00
IUUC-Sha-106971	Sarcophilus harrisii	78.78	0.00e+00	773.00
IUUC-Sit-110442	Setaria italica	27.44	1.00e-28	121.00
IUUC-Stu-112223	Solanum tuberosum	22.86	2.00e-16	79.70
IUUC-Ssc-116397	Sus scrofa	92.65	0.00e+00	879.00
IUUC-Tgu-117446	Taeniopygia guttata	69.15	0.00e+00	641.00
IUUC-Tru-118268	Takifugu rubripes	57.80	3.00e-142	498.00
IUUC-Tsy-119484	Tarsius syrichta	92.91	4.00e-54	205.00
IUUC-Tni-119735	Tetraodon nigroviridis	54.58	1.00e-122	432.00
IUUC-Tca-121660	Theobroma cacao	25.37	3.00e-28	119.00
IUUC-Tae-125383	Triticum aestivum	27.33	8.00e-29	121.00
IUUC-Tur-126458	Triticum urartu	28.03	4.00e-27	115.00
IUUC-Tbe-127740	Tupaia belangeri	87.04	0.00e+00	801.00
IUUC-Ttr-129273	Tursiops truncatus	90.14	0.00e+00	844.00
IUUC-Vvi-131177	Vitis vinifera	25.05	5.00e-22	99.40
IUUC-Xtr-132374	Xenopus tropicalis	65.07	2.00e-171	595.00
IUUC-Xma-133267	Xiphophorus maculatus	60.52	2.00e-158	552.00
IUUC-Yli-134571	Yarrowia lipolytica	23.96	3.00e-11	63.50
IUUC-Zma-135796	Zea mays	27.30	2.00e-18	87.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence