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Tag Content
UUCD2 ID IUUC-Gga-040668
UUCD1 version UUC-GaG-00914
Ensembl Protein ID ENSGALP00000016104.5
UniProt Accession F1NH67; F1NH67_CHICK
Genbank Protein ID ENSGALP00000016104
Protein Name Uncharacterized protein
Genbank Nucleotide ID AADN04000302
Gene Name CYLD
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGALG00000003753.5 ENSGALT00000016123.5 ENSGALP00000016104.5
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.80e-23 83.6 591 947
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeq 89
           G++ + N+CY++S+L cL++++++ + +l + kek + e ++e+++ l +++ + ++     + +k ++ r++l+++++++    ++e+
   Q: 591  GIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGyVCATKIMKLRKILEKVEAASGF--TSEE 677
           999***************************99999999999999999999****999887899**************988875..899* PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksq.ik...clecdnvs.sreepfldls 173
           +D +Efl++l++++ +       k ++  ++ +++   ++  +k++k +  +i++l+++++ ++ +k    ++c  ++  r+ + +++ 
   Q: 678  KDPEEFLNILFHHILRVE--PLLKIRSAGQKVQDCYFYQIFMDKNEKVGVPTIQQLLEWSFINSnLKfaeAPSCLIIQmPRFGKDFKMF 764
           ****************99..88999999999999**************************9854144444799****999********9 PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenk.yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL.. 259
            ++  + e    +++d+Le+  ++++++g  + y+c++c+++ + +   k+k+++++   +           ++++ ++ +++p+ L  
   Q: 765  NKIFPSLEL---NITDLLEDTPRQCRICGGLAmYECRECYEDADISAG-KIKQFCKTCNTQVHLH-----PRRQSHKFNPLSLPKDLpd 844
           999999988...***************987655********9985554.8888888654444333.....1223445778888866511 PP
   S: 260  .dlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk..WllfdD.............skVtevke.eevleetg.... 327
            d ++ c+        ++k eL+av++ +      HYva+vk  +++  Wl fd               +Vt+++e  e l+++     
   Q: 845  wDWRHGCIP-------YQKMELFAVLCIET----SHYVAFVKYGRDDsaWLFFDSmadrdggqngfniPQVTPCPEvGEYLKMSVeelh 922
           133344444.......99*********999....9********6655679999999999999999999566666544555554445556 PP
   S: 328  ...............staYvlfYkr 337
                          ++aY+++Y++
   Q: 923  sldsrkiqgcarrllCDAYMCMYQS 947
           666777777999***********85 PP
   
Organism Gallus gallus
Protein Sequence
(Fasta)
MSSGLWSQEK GSSSYWEERI FYLLLQECSV IDKQTQKLLK VPKGSIGQFF QDRSSMGHSR 60
NIPCKGKKLQ IGLKILEQPH AVLFVDEKDV IEINEKLAEL LLAITNCEER YSLFKSKSRL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Gga-040668|DUB,USP|Gallus gallus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCCGTGCGT TGCGCCGTGG TGGTGCTGCC GGGGTGTGGG TGGGAGGGGC GGCCTTGAAG 60
GCAGCAGCGC CGGGGCTTTC CGCCGGTTAC CGACTGGGCT CGTTCTTCCT CCTGGGCGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Gga-040668|DUB,USP|Gallus gallus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR000938--CAP-Gly_domain
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3
Pfam

PF01302--CAP_GLY
PF00443--UCH
SMART

SM01052--CAP_GLY
Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0097542--C:ciliary tip
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0030496--C:midbody
GO:0005819--C:spindle
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0043369--P:CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
GO:0048872--P:homeostasis of number of cells
GO:0045087--P:innate immune response
GO:0070266--P:necroptotic process
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0045581--P:negative regulation of T cell differentiation
GO:1903829--P:positive regulation of cellular protein localization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0045582--P:positive regulation of T cell differentiation
GO:0050862--P:positive regulation of T cell receptor signaling pathway
GO:1990108--P:protein linear deubiquitination
GO:0045577--P:regulation of B cell differentiation
GO:1902017--P:regulation of cilium assembly
GO:2001242--P:regulation of intrinsic apoptotic signaling pathway
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0007346--P:regulation of mitotic cell cycle
GO:0043393--P:regulation of protein binding
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway
GO:1901026--P:ripoptosome assembly involved in necroptotic process
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG gga:415725
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001298 Ailuropoda melanoleuca 87.25 0.00e+00 1747.00
IUUC-Apl-003356 Anas platyrhynchos 97.69 0.00e+00 1883.00
IUUC-Aca-004402 Anolis carolinensis 83.84 0.00e+00 1572.00
IUUC-Ame-011581 Astyanax mexicanus 69.24 0.00e+00 1255.00
IUUC-Bta-012359 Bos taurus 87.32 0.00e+00 1742.00
IUUC-Cel-018528 Caenorhabditis elegans 35.17 3.00e-57 216.00
IUUC-Cja-018797 Callithrix jacchus 87.04 0.00e+00 1745.00
IUUC-Cfa-020264 Canis familiaris 87.63 0.00e+00 1752.00
IUUC-Cpo-022057 Cavia porcellus 87.25 0.00e+00 1748.00
IUUC-Csa-023093 Chlorocebus sabaeus 87.84 0.00e+00 1755.00
IUUC-Cho-024486 Choloepus hoffmanni 85.29 4.00e-159 555.00
IUUC-Cin-025179 Ciona intestinalis 43.78 7.00e-119 420.00
IUUC-Dre-028233 Danio rerio 69.01 0.00e+00 1286.00
IUUC-Dno-029496 Dasypus novemcinctus 87.21 0.00e+00 1748.00
IUUC-Dor-030919 Dipodomys ordii 82.45 0.00e+00 1625.00
IUUC-Dme-032159 Drosophila melanogaster 46.14 1.00e-124 439.00
IUUC-Ete-032734 Echinops telfairi 82.45 0.00e+00 1625.00
IUUC-Eca-033350 Equus caballus 87.63 0.00e+00 1757.00
IUUC-Eeu-034566 Erinaceus europaeus 92.47 8.00e-109 388.00
IUUC-Fca-035632 Felis catus 84.51 0.00e+00 1186.00
IUUC-Fal-037313 Ficedula albicollis 91.09 0.00e+00 1735.00
IUUC-Gmo-039239 Gadus morhua 68.12 0.00e+00 1229.00
IUUC-Gac-042630 Gasterosteus aculeatus 68.61 0.00e+00 1236.00
IUUC-Ggo-044462 Gorilla gorilla 87.57 0.00e+00 1750.00
IUUC-Hsa-045846 Homo sapiens 87.57 0.00e+00 1751.00
IUUC-Itr-048894 Ictidomys tridecemlineatus 86.31 0.00e+00 777.00
IUUC-Lch-050303 Latimeria chalumnae 71.30 0.00e+00 1330.00
IUUC-Loc-052190 Lepisosteus oculatus 70.92 0.00e+00 1301.00
IUUC-Laf-054480 Loxodonta africana 89.47 0.00e+00 740.00
IUUC-Mcc-055849 Macaca mulatta 87.77 0.00e+00 1754.00
IUUC-Meu-056755 Macropus eugenii 76.78 0.00e+00 822.00
IUUC-Mga-059561 Meleagris gallopavo 98.64 0.00e+00 1885.00
IUUC-Mmr-060942 Microcebus murinus 87.46 0.00e+00 1739.00
IUUC-Mdo-062618 Monodelphis domestica 87.77 0.00e+00 1750.00
IUUC-Mmu-063843 Mus musculus 86.21 0.00e+00 1681.00
IUUC-Mpu-066919 Mustela putorius furo 87.63 0.00e+00 1754.00
IUUC-Mlu-066983 Myotis lucifugus 84.28 0.00e+00 1664.00
IUUC-Nle-069893 Nomascus leucogenys 87.46 0.00e+00 1749.00
IUUC-Opr-071181 Ochotona princeps 79.91 0.00e+00 1459.00
IUUC-Ont-071697 Oreochromis niloticus 68.07 0.00e+00 1229.00
IUUC-Oan-073658 Ornithorhynchus anatinus 87.21 0.00e+00 1716.00
IUUC-Ocu-074954 Oryctolagus cuniculus 87.67 0.00e+00 1754.00
IUUC-Ola-086523 Oryzias latipes 66.67 0.00e+00 1201.00
IUUC-Oga-089003 Otolemur garnettii 87.57 0.00e+00 1756.00
IUUC-Oar-090376 Ovis aries 86.89 0.00e+00 1744.00
IUUC-Ptr-090520 Pan troglodytes 85.79 0.00e+00 1700.00
IUUC-Pan-092281 Papio anubis 87.84 0.00e+00 1755.00
IUUC-Psi-093047 Pelodiscus sinensis 94.24 0.00e+00 1709.00
IUUC-Pma-094575 Petromyzon marinus 55.25 8.00e-67 246.00
IUUC-Pfo-096358 Poecilia formosa 67.25 0.00e+00 1172.00
IUUC-Pab-097740 Pongo abelii 87.15 0.00e+00 1743.00
IUUC-Pca-100461 Procavia capensis 78.35 0.00e+00 1402.00
IUUC-Pva-102134 Pteropus vampyrus 78.37 0.00e+00 1538.00
IUUC-Rno-105807 Rattus norvegicus 85.12 0.00e+00 1652.00
IUUC-Sha-107236 Sarcophilus harrisii 88.05 0.00e+00 1694.00
IUUC-Sar-113366 Sorex araneus 94.89 0.00e+00 911.00
IUUC-Tgu-117201 Taeniopygia guttata 93.31 0.00e+00 1777.00
IUUC-Tru-117953 Takifugu rubripes 68.99 0.00e+00 1228.00
IUUC-Tsy-119610 Tarsius syrichta 85.48 0.00e+00 1705.00
IUUC-Tni-120743 Tetraodon nigroviridis 52.86 4.00e-138 485.00
IUUC-Tbe-128155 Tupaia belangeri 70.68 0.00e+00 681.00
IUUC-Ttr-128942 Tursiops truncatus 81.92 0.00e+00 1625.00
IUUC-Vpa-130281 Vicugna pacos 77.51 0.00e+00 1503.00
IUUC-Xtr-132627 Xenopus tropicalis 78.19 0.00e+00 1448.00
Created Date 25-Jun-2017

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