iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044683

UUCD1 version

UUC-GoG-00819

Ensembl Protein ID

ENSGGOP00000021835.1

UniProt Accession

G3S190; G3S190_GORGO

Protein Name

Uncharacterized protein

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000009409.2	ENSGGOT00000022504.1	ENSGGOP00000021835.1
ENSGGOG00000009409.2	ENSGGOT00000009450.2	ENSGGOP00000009196.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-24	84.8	365	396
UBD/Beta-Prp	6.70e-45	153.9	278	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 365  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 396
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 278  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 366
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 367  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 453
           ******99999.********************988874555555.55555555558*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 454  RRMVCCSAWSEDHpvCNLFTCGFDRQAIGWNIN 486
           ************9888899***********986 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MPTESASCST ARQTKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLEYR EYIISVVNWL NIKGLNLEEA NNGKGLICGN SFVCDGLLST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCACAG AAAGCGCAAG TTGTTCGACT GCTCGCCAAA CAAAACAGAA GCGCAAATCC 60
CATAGCCTTT CTATACGAAG AACTAACAGC TCGGAGCAGG AGAGGACGGG ACTGCCAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	87.90	0.00e+00	863.00
IUUC-Apl-003647	Anas platyrhynchos	86.67	0.00e+00	848.00
IUUC-Aca-004759	Anolis carolinensis	85.66	0.00e+00	855.00
IUUC-Ame-011103	Astyanax mexicanus	50.30	4.00e-119	421.00
IUUC-Bta-012718	Bos taurus	87.50	0.00e+00	858.00
IUUC-Cel-018499	Caenorhabditis elegans	40.77	5.00e-90	324.00
IUUC-Cja-019492	Callithrix jacchus	90.71	0.00e+00	916.00
IUUC-Cfa-020199	Canis familiaris	87.50	0.00e+00	893.00
IUUC-Cpo-022500	Cavia porcellus	82.86	0.00e+00	844.00
IUUC-Csa-023567	Chlorocebus sabaeus	91.52	0.00e+00	922.00
IUUC-Cho-025071	Choloepus hoffmanni	61.13	1.00e-161	562.00
IUUC-Cin-025460	Ciona intestinalis	42.98	9.00e-97	347.00
IUUC-Csv-026042	Ciona savignyi	45.52	2.00e-102	365.00
IUUC-Dre-028214	Danio rerio	78.54	0.00e+00	787.00
IUUC-Dno-029826	Dasypus novemcinctus	88.70	0.00e+00	736.00
IUUC-Dor-030967	Dipodomys ordii	88.91	0.00e+00	813.00
IUUC-Dme-031936	Drosophila melanogaster	48.84	9.00e-115	407.00
IUUC-Ete-032452	Echinops telfairi	85.83	0.00e+00	864.00
IUUC-Eca-033278	Equus caballus	88.71	0.00e+00	902.00
IUUC-Eeu-034592	Erinaceus europaeus	76.32	0.00e+00	748.00
IUUC-Fca-036431	Felis catus	88.53	0.00e+00	898.00
IUUC-Fal-037149	Ficedula albicollis	85.86	0.00e+00	842.00
IUUC-Gmo-038476	Gadus morhua	74.55	0.00e+00	712.00
IUUC-Gga-041099	Gallus gallus	86.26	0.00e+00	847.00
IUUC-Gac-042374	Gasterosteus aculeatus	77.60	0.00e+00	746.00
IUUC-Hsa-046658	Homo sapiens	91.90	0.00e+00	928.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	89.23	0.00e+00	833.00
IUUC-Lch-050571	Latimeria chalumnae	77.19	0.00e+00	793.00
IUUC-Loc-052652	Lepisosteus oculatus	75.29	0.00e+00	782.00
IUUC-Laf-053712	Loxodonta africana	87.17	0.00e+00	882.00
IUUC-Mcc-055521	Macaca mulatta	91.52	0.00e+00	922.00
IUUC-Meu-056324	Macropus eugenii	82.59	0.00e+00	805.00
IUUC-Mga-060114	Meleagris gallopavo	86.09	0.00e+00	847.00
IUUC-Mmr-061176	Microcebus murinus	89.29	0.00e+00	903.00
IUUC-Mdo-061888	Monodelphis domestica	86.69	0.00e+00	834.00
IUUC-Mmu-063977	Mus musculus	89.11	0.00e+00	906.00
IUUC-Mpu-066220	Mustela putorius furo	77.01	5.00e-163	566.00
IUUC-Mlu-068155	Myotis lucifugus	88.71	0.00e+00	901.00
IUUC-Nle-069964	Nomascus leucogenys	91.92	0.00e+00	926.00
IUUC-Opr-070925	Ochotona princeps	82.12	2.00e-126	445.00
IUUC-Ont-071317	Oreochromis niloticus	79.64	0.00e+00	762.00
IUUC-Oan-072952	Ornithorhynchus anatinus	87.30	0.00e+00	860.00
IUUC-Ocu-073913	Oryctolagus cuniculus	89.11	0.00e+00	907.00
IUUC-Ola-087024	Oryzias latipes	78.27	0.00e+00	802.00
IUUC-Oga-087945	Otolemur garnettii	89.31	0.00e+00	908.00
IUUC-Oar-089854	Ovis aries	87.90	0.00e+00	851.00
IUUC-Ptr-091486	Pan troglodytes	92.11	0.00e+00	929.00
IUUC-Pan-091738	Papio anubis	91.52	0.00e+00	922.00
IUUC-Psi-093953	Pelodiscus sinensis	85.69	0.00e+00	845.00
IUUC-Pma-094560	Petromyzon marinus	70.23	0.00e+00	701.00
IUUC-Pfo-097222	Poecilia formosa	79.15	0.00e+00	761.00
IUUC-Pab-098778	Pongo abelii	86.84	0.00e+00	860.00
IUUC-Pca-100852	Procavia capensis	85.22	0.00e+00	849.00
IUUC-Pva-103130	Pteropus vampyrus	79.34	7.00e-108	384.00
IUUC-Rno-105848	Rattus norvegicus	85.28	0.00e+00	846.00
IUUC-Sha-106750	Sarcophilus harrisii	86.90	0.00e+00	861.00
IUUC-Sar-113749	Sorex araneus	80.16	0.00e+00	797.00
IUUC-Ssc-115691	Sus scrofa	86.46	0.00e+00	844.00
IUUC-Tgu-117365	Taeniopygia guttata	85.05	0.00e+00	805.00
IUUC-Tru-117595	Takifugu rubripes	78.02	0.00e+00	759.00
IUUC-Tsy-118973	Tarsius syrichta	77.62	2.00e-156	545.00
IUUC-Tni-120545	Tetraodon nigroviridis	77.51	0.00e+00	791.00
IUUC-Tbe-127976	Tupaia belangeri	71.86	0.00e+00	687.00
IUUC-Ttr-128472	Tursiops truncatus	86.23	0.00e+00	867.00
IUUC-Xtr-132621	Xenopus tropicalis	84.24	0.00e+00	824.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence