iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072841

UUCD1 version

UUC-OrA-00228

Ensembl Protein ID

ENSOANP00000013596.2

UniProt Accession

F6VSM1; F6VSM1_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KLHL23

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000008541.3	ENSOANT00000013599.2	ENSOANP00000013596.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.70e-15	57.3	68	136
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.10e-08	31.9	168	188

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +D+ l++  g+ f++hk+vLaa+S +F+a+f+ +++e+  k++++++++++  ++ l+++ Y+++++++e
   Q: 68   TDIALQCPsGVTFHCHKAVLAACSNYFKAMFTADMKEKF-KDKIKLSGISHAILEGLIDYAYSSQIKITE 136
           689999999*****************************9.*************************98865 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkd 21
           l+Nc+g+ +fA+l+ c++L +
   Q: 168  LDNCIGMHSFAELHMCTELEK 188
           69*****************87 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MPRKGFTLQK LISEKTRDLA PVESSVLVWT SAMALKGQED YTYVFKDPSH PVDFLDAFRT 60
FYHDGLFTDI ALQCPSGVTF HCHKAVLAAC SNYFKAMFTA DMKEKFKDKI KLSGISHAIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTATCAGC AAAATGACCG TTTACTAAGT ACCAAATTAA AATAGAAAAA AAAATCAACA 60
GAGAAGAGTA GATGTTCTCA ACAGTGCTTT GAAGAACATG TCGACTGGTG ACGACACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001639	Ailuropoda melanoleuca	84.79	0.00e+00	1015.00
IUUC-Apl-003948	Anas platyrhynchos	74.90	0.00e+00	834.00
IUUC-Aca-005045	Anolis carolinensis	74.19	0.00e+00	900.00
IUUC-Ame-011013	Astyanax mexicanus	61.68	0.00e+00	756.00
IUUC-Bta-013159	Bos taurus	84.79	0.00e+00	1013.00
IUUC-Cja-018886	Callithrix jacchus	84.41	0.00e+00	1018.00
IUUC-Cfa-020205	Canis familiaris	84.95	0.00e+00	1020.00
IUUC-Cpo-022295	Cavia porcellus	84.23	0.00e+00	1009.00
IUUC-Cho-025089	Choloepus hoffmanni	83.30	0.00e+00	813.00
IUUC-Dre-027681	Danio rerio	60.00	0.00e+00	738.00
IUUC-Dno-029078	Dasypus novemcinctus	82.42	0.00e+00	811.00
IUUC-Ete-033011	Echinops telfairi	73.91	0.00e+00	844.00
IUUC-Eca-033213	Equus caballus	84.95	0.00e+00	1020.00
IUUC-Fca-035884	Felis catus	85.13	0.00e+00	1020.00
IUUC-Fal-036897	Ficedula albicollis	74.73	0.00e+00	902.00
IUUC-Gmo-038594	Gadus morhua	55.69	0.00e+00	686.00
IUUC-Ggr-039747	Gaeumannomyces graminis	23.79	5.00e-07	47.80
IUUC-Gga-040791	Gallus gallus	74.01	0.00e+00	909.00
IUUC-Gac-042512	Gasterosteus aculeatus	60.68	0.00e+00	749.00
IUUC-Ggo-044837	Gorilla gorilla	84.77	0.00e+00	1018.00
IUUC-Hsa-046231	Homo sapiens	84.95	0.00e+00	1019.00
IUUC-Itr-048084	Ictidomys tridecemlineatus	85.48	0.00e+00	1024.00
IUUC-Lch-050412	Latimeria chalumnae	71.68	0.00e+00	895.00
IUUC-Loc-052033	Lepisosteus oculatus	66.67	0.00e+00	804.00
IUUC-Laf-053908	Loxodonta africana	84.59	0.00e+00	1016.00
IUUC-Mcc-054734	Macaca mulatta	84.77	0.00e+00	1018.00
IUUC-Meu-055982	Macropus eugenii	85.48	0.00e+00	1020.00
IUUC-Mga-059670	Meleagris gallopavo	72.99	0.00e+00	895.00
IUUC-Mmr-060692	Microcebus murinus	85.13	0.00e+00	1021.00
IUUC-Mdo-062419	Monodelphis domestica	86.02	0.00e+00	1023.00
IUUC-Mmu-063752	Mus musculus	84.41	0.00e+00	1014.00
IUUC-Mpu-066515	Mustela putorius furo	85.13	0.00e+00	1021.00
IUUC-Mlu-068004	Myotis lucifugus	78.67	0.00e+00	982.00
IUUC-Nle-069163	Nomascus leucogenys	84.95	0.00e+00	1019.00
IUUC-Opr-070823	Ochotona princeps	83.52	0.00e+00	813.00
IUUC-Ont-071629	Oreochromis niloticus	62.81	0.00e+00	759.00
IUUC-Ocu-074300	Oryctolagus cuniculus	85.13	0.00e+00	1023.00
IUUC-Ola-087025	Oryzias latipes	56.94	0.00e+00	710.00
IUUC-Oga-088442	Otolemur garnettii	83.73	0.00e+00	973.00
IUUC-Oar-089237	Ovis aries	84.44	0.00e+00	1009.00
IUUC-Ptr-091541	Pan troglodytes	84.77	0.00e+00	1017.00
IUUC-Psi-093748	Pelodiscus sinensis	77.42	0.00e+00	941.00
IUUC-Pma-094302	Petromyzon marinus	44.64	7.00e-103	366.00
IUUC-Pfo-097039	Poecilia formosa	61.94	0.00e+00	731.00
IUUC-Pab-098280	Pongo abelii	84.95	0.00e+00	1019.00
IUUC-Pca-100840	Procavia capensis	76.34	0.00e+00	892.00
IUUC-Pva-102152	Pteropus vampyrus	84.41	0.00e+00	1012.00
IUUC-Rno-105710	Rattus norvegicus	83.99	0.00e+00	1008.00
IUUC-Sha-106991	Sarcophilus harrisii	84.77	0.00e+00	1016.00
IUUC-Smo-109101	Selaginella moellendorffii	27.32	3.00e-13	68.60
IUUC-Sar-112931	Sorex araneus	84.59	0.00e+00	1015.00
IUUC-Ssc-116016	Sus scrofa	84.08	0.00e+00	1011.00
IUUC-Tgu-116999	Taeniopygia guttata	74.91	0.00e+00	914.00
IUUC-Tsy-119071	Tarsius syrichta	84.23	0.00e+00	1010.00
IUUC-Tni-120149	Tetraodon nigroviridis	57.94	0.00e+00	676.00
IUUC-Tbe-127651	Tupaia belangeri	84.95	0.00e+00	1019.00
IUUC-Ttr-128402	Tursiops truncatus	84.59	0.00e+00	1019.00
IUUC-Vpa-130186	Vicugna pacos	83.33	0.00e+00	999.00
IUUC-Xtr-132379	Xenopus tropicalis	68.28	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence