iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033992

Ensembl Protein ID

ENSECAP00000019416.1

UniProt Accession

F6YKY8; F6YKY8_HORSE

Protein Name

Uncharacterized protein

Gene Name

NAE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021954.1	ENSECAT00000023443.1	ENSECAP00000019416.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.00e-89	299.3	1	436

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 78   aealkelnpdvnveaheesiteleeeiv.FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd. 164
           +e+l+eln dv+++++ees+++l ++++ Ff++f++Vv+++ ++++ ++++++++n ++pl+ ++t+Gl+G++r+iik++++++s++d 
   Q: 1    MEFLQELNNDVSGSFVEESPENLLDNDPsFFCRFTIVVATQLPESTLLRLADVLWNSQIPLLVCRTYGLVGYMRIIIKEHPVIESHPDn 89
           589************************************************************************************** PP
   S: 165  ..dppqktiPfctlketpn.........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks......edeenfee 236
             +++++++Pf++l+e+++         +++++++w+v+++k+l+++++e++++ +++++eke+++d++++++ +      edeenfee
   Q: 90   alEDLRLDKPFPELREHFQsydlehmekKDHSHTPWIVIVAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKnengapEDEENFEE 178
           *****************99999999998***********************************************9************* PP
   S: 237  aieiavkafakttins.ikqllksfecdivtkskspfwv.................................................. 274
           ai+++++a+++t+i+s i++++++++c ++tk++++fw+                                                  
   Q: 179  AIKNVNTALNTTQIPSsIEDIFNDDRCINITKQTPSFWIlaralkefvakegqgnlpvrgtipdmiadsgkyiklqnvyrekakkdaaa 267
           ***************************************************************************************** PP
   S: 275  .........................sfcsnaealqvp...........ekvekdeevvkasap.....lylllralerfekkkgrkpge 322
                                     +c+n++ l+v            ++v+kde+++++++p     lyl+lra++rf+k++gr+pg+
   Q: 268  vgnhvakllqsigqapesisekelkLLCNNSAFLRVVrcrslaeeyglDTVNKDEIISSMDNPdneivLYLMLRAVDRFHKQHGRYPGV 356
           ************************999999999997777777777888**************9************************** PP
   S: 323  lsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfdae 404
           +++++++d+  + +++t ++    +++g++ +++dd+++e++++++++ +t++a++gG+aaqEviK+++++f+ ++n++++ ++
   Q: 357  SNYQVEEDIgkLKSCLTGFL----QEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 436
           *********999********....********************************************************9776 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MEFLQELNND VSGSFVEESP ENLLDNDPSF FCRFTIVVAT QLPESTLLRL ADVLWNSQIP 60
LLVCRTYGLV GYMRIIIKEH PVIESHPDNA LEDLRLDKPF PELREHFQSY DLEHMEKKDH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGCGCCTG CGCGCTCGTG GAGGTGTTGG CGGTGCCCGG CGGGGGCTCG GCTGTTATTC 60
GCGCGGCGGG CGCGGCCATG GCGCAACCAG GGGAAGCTGC TGAAGGAGCA GAAGTACGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0033314--P:mitotic DNA replication checkpoint
GO:0051402--P:neuron apoptotic process
GO:0045116--P:protein neddylation
GO:0043523--P:regulation of neuron apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	39.87	2.00e-96	345.00
IUUC-Aml-002333	Ailuropoda melanoleuca	97.53	0.00e+00	913.00
IUUC-Atr-002644	Amborella trichopoda	38.95	9.00e-86	310.00
IUUC-Apl-003446	Anas platyrhynchos	84.46	0.00e+00	784.00
IUUC-Aca-004450	Anolis carolinensis	80.18	0.00e+00	766.00
IUUC-Aly-006187	Arabidopsis lyrata	38.06	2.00e-97	349.00
IUUC-Ath-007600	Arabidopsis thaliana	38.51	4.00e-98	352.00
IUUC-Ago-007900	Ashbya gossypii	25.06	7.00e-27	114.00
IUUC-Acl-008333	Aspergillus clavatus	31.52	6.00e-56	211.00
IUUC-Afl-008529	Aspergillus flavus	34.42	1.00e-62	234.00
IUUC-Afu-009071	Aspergillus fumigatus	30.48	3.00e-55	209.00
IUUC-Ani-009443	Aspergillus nidulans	30.70	7.00e-54	204.00
IUUC-Ang-009669	Aspergillus niger	29.78	9.00e-56	211.00
IUUC-Aor-009914	Aspergillus oryzae	33.62	2.00e-59	223.00
IUUC-Ate-010450	Aspergillus terreus	31.73	5.00e-58	218.00
IUUC-Ame-011183	Astyanax mexicanus	70.72	0.00e+00	684.00
IUUC-Bgr-012111	Blumeria graminis	28.51	9.00e-37	147.00
IUUC-Bta-012583	Bos taurus	97.98	0.00e+00	915.00
IUUC-Bci-013892	Botrytis cinerea	28.60	3.00e-43	169.00
IUUC-Bdi-014592	Brachypodium distachyon	40.54	5.00e-98	351.00
IUUC-Bol-016399	Brassica oleracea	37.84	4.00e-95	342.00
IUUC-Bra-017506	Brassica rapa	36.40	1.00e-91	330.00
IUUC-Cel-018456	Caenorhabditis elegans	33.62	2.00e-68	253.00
IUUC-Cja-020007	Callithrix jacchus	97.75	0.00e+00	916.00
IUUC-Cfa-020324	Canis familiaris	97.75	0.00e+00	913.00
IUUC-Cpo-022248	Cavia porcellus	69.27	2.00e-165	575.00
IUUC-Csa-023149	Chlorocebus sabaeus	98.20	0.00e+00	919.00
IUUC-Cho-024537	Choloepus hoffmanni	85.39	0.00e+00	781.00
IUUC-Cin-025763	Ciona intestinalis	46.09	5.00e-118	417.00
IUUC-Csv-026113	Ciona savignyi	43.56	1.00e-110	393.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	28.68	6.00e-39	155.00
IUUC-Cne-026884	Cryptococcus neoformans	26.68	1.00e-46	181.00
IUUC-Dre-028140	Danio rerio	71.62	0.00e+00	698.00
IUUC-Dno-030033	Dasypus novemcinctus	97.92	0.00e+00	789.00
IUUC-Dor-030513	Dipodomys ordii	68.37	2.00e-115	409.00
IUUC-Dse-031536	Dothistroma septosporum	30.96	5.00e-57	215.00
IUUC-Dme-031683	Drosophila melanogaster	41.81	2.00e-95	342.00
IUUC-Ete-032420	Echinops telfairi	82.02	0.00e+00	751.00
IUUC-Eeu-034713	Erinaceus europaeus	80.71	2.00e-118	419.00
IUUC-Fca-036548	Felis catus	96.85	0.00e+00	902.00
IUUC-Fal-037600	Ficedula albicollis	80.67	0.00e+00	751.00
IUUC-Fox-038037	Fusarium oxysporum	29.16	6.00e-48	185.00
IUUC-Fso-038387	Fusarium solani	30.44	7.00e-50	191.00
IUUC-Gmo-038562	Gadus morhua	69.73	0.00e+00	679.00
IUUC-Ggr-040005	Gaeumannomyces graminis	30.96	3.00e-46	179.00
IUUC-Gga-041129	Gallus gallus	84.46	0.00e+00	782.00
IUUC-Gac-042558	Gasterosteus aculeatus	70.85	0.00e+00	681.00
IUUC-Gma-043610	Glycine max	39.46	4.00e-92	332.00
IUUC-Ggo-045611	Gorilla gorilla	97.98	0.00e+00	919.00
IUUC-Hsa-046563	Homo sapiens	97.98	0.00e+00	917.00
IUUC-Hvu-047790	Hordeum vulgare	38.11	4.00e-77	281.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	97.98	0.00e+00	916.00
IUUC-Kpa-049309	Komagataella pastoris	32.58	6.00e-61	228.00
IUUC-Lch-050038	Latimeria chalumnae	75.23	0.00e+00	708.00
IUUC-Lpe-051535	Leersia perrieri	40.53	4.00e-90	325.00
IUUC-Loc-051917	Lepisosteus oculatus	71.46	0.00e+00	697.00
IUUC-Lma-053112	Leptosphaeria maculans	32.21	3.00e-61	229.00
IUUC-Laf-053690	Loxodonta africana	96.85	0.00e+00	908.00
IUUC-Mcc-055117	Macaca mulatta	98.43	0.00e+00	922.00
IUUC-Meu-056761	Macropus eugenii	83.14	0.00e+00	731.00
IUUC-Mor-057230	Magnaporthe oryzae	29.66	5.00e-50	192.00
IUUC-Mpo-057514	Magnaporthe poae	30.47	2.00e-44	173.00
IUUC-Mtr-058551	Medicago truncatula	38.48	7.00e-89	321.00
IUUC-Mla-059183	Melampsora laricipopulina	32.13	1.00e-67	250.00
IUUC-Mga-060144	Meleagris gallopavo	83.78	0.00e+00	775.00
IUUC-Mvi-060221	Microbotryum violaceum	32.03	2.00e-52	200.00
IUUC-Mmr-061325	Microcebus murinus	97.30	0.00e+00	909.00
IUUC-Mdo-062532	Monodelphis domestica	91.69	0.00e+00	861.00
IUUC-Mmu-063956	Mus musculus	97.30	0.00e+00	911.00
IUUC-Mac-064521	Musa acuminata	38.74	1.00e-93	337.00
IUUC-Mpu-066716	Mustela putorius furo	97.34	0.00e+00	847.00
IUUC-Mlu-067459	Myotis lucifugus	97.09	0.00e+00	906.00
IUUC-Nfi-068245	Neosartorya fischeri	30.92	1.00e-55	210.00
IUUC-Ncr-068910	Neurospora crassa	30.11	6.00e-51	195.00
IUUC-Nle-070034	Nomascus leucogenys	97.98	0.00e+00	917.00
IUUC-Opr-070552	Ochotona princeps	86.06	0.00e+00	722.00
IUUC-Ont-071426	Oreochromis niloticus	71.85	0.00e+00	699.00
IUUC-Oan-073389	Ornithorhynchus anatinus	84.04	0.00e+00	777.00
IUUC-Ocu-074911	Oryctolagus cuniculus	96.40	0.00e+00	908.00
IUUC-Oba-075437	Oryza barthii	40.99	6.00e-99	354.00
IUUC-Obr-076684	Oryza brachyantha	41.22	3.00e-94	338.00
IUUC-Ogl-077170	Oryza glaberrima	40.99	6.00e-99	354.00
IUUC-Ogu-078844	Oryza glumaepatula	41.81	5.00e-92	331.00
IUUC-Oin-079105	Oryza indica	40.99	2.00e-98	352.00
IUUC-Olo-080943	Oryza longistaminata	41.49	7.00e-93	334.00
IUUC-Oni-082891	Oryza nivara	40.99	3.00e-98	352.00
IUUC-Opu-083457	Oryza punctata	40.99	2.00e-98	353.00
IUUC-Oru-084960	Oryza rufipogon	41.49	5.00e-93	334.00
IUUC-Osa-085358	Oryza sativa	41.22	5.00e-99	354.00
IUUC-Ola-086420	Oryzias latipes	71.58	7.00e-168	582.00
IUUC-Olu-087625	Ostreococcus lucimarinus	31.21	5.00e-47	182.00
IUUC-Oga-088810	Otolemur garnettii	96.40	0.00e+00	904.00
IUUC-Oar-089196	Ovis aries	98.43	0.00e+00	917.00
IUUC-Ptr-090617	Pan troglodytes	98.20	0.00e+00	920.00
IUUC-Pan-092761	Papio anubis	97.98	0.00e+00	918.00
IUUC-Psi-093191	Pelodiscus sinensis	87.61	0.00e+00	831.00
IUUC-Pma-094380	Petromyzon marinus	58.25	4.00e-150	524.00
IUUC-Pno-095084	Phaeosphaeria nodorum	28.60	2.00e-47	184.00
IUUC-Ppa-095875	Physcomitrella patens	37.81	2.00e-90	326.00
IUUC-Pfo-096467	Poecilia formosa	70.92	0.00e+00	684.00
IUUC-Pab-098255	Pongo abelii	97.46	0.00e+00	733.00
IUUC-Pop-099722	Populus trichocarpa	38.96	2.00e-96	346.00
IUUC-Pca-100807	Procavia capensis	72.77	7.00e-77	280.00
IUUC-Ppe-101280	Prunus persica	37.58	2.00e-93	335.00
IUUC-Pva-102333	Pteropus vampyrus	92.58	0.00e+00	854.00
IUUC-Pgr-103401	Puccinia graminis	32.36	5.00e-62	232.00
IUUC-Ptt-103889	Puccinia triticina	26.90	3.00e-42	166.00
IUUC-Pte-104355	Pyrenophora teres	33.05	5.00e-65	241.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	33.47	5.00e-66	245.00
IUUC-Rno-105810	Rattus norvegicus	97.30	0.00e+00	910.00
IUUC-Sce-106397	Saccharomyces cerevisiae	25.38	6.00e-25	108.00
IUUC-Sha-106770	Sarcophilus harrisii	88.54	6.00e-103	366.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	31.32	6.00e-58	218.00
IUUC-Spo-108276	Schizosaccharomyces pombe	31.61	2.00e-56	213.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	28.10	2.00e-45	176.00
IUUC-Smo-109296	Selaginella moellendorffii	40.90	4.00e-96	345.00
IUUC-Sit-110157	Setaria italica	42.79	8.00e-106	377.00
IUUC-Sly-111105	Solanum lycopersicum	37.83	5.00e-93	334.00
IUUC-Stu-112469	Solanum tuberosum	38.43	5.00e-95	341.00
IUUC-Sar-113083	Sorex araneus	69.44	2.00e-176	611.00
IUUC-Sbi-113813	Sorghum bicolor	42.79	9.00e-105	374.00
IUUC-Sre-115058	Sporisorium reilianum	36.14	9.00e-61	228.00
IUUC-Tgu-116772	Taeniopygia guttata	80.63	0.00e+00	746.00
IUUC-Tru-118686	Takifugu rubripes	69.59	0.00e+00	684.00
IUUC-Tsy-119111	Tarsius syrichta	97.88	1.00e-107	383.00
IUUC-Tni-120231	Tetraodon nigroviridis	69.80	0.00e+00	676.00
IUUC-Tca-121491	Theobroma cacao	38.34	9.00e-88	317.00
IUUC-Tre-122103	Trichoderma reesei	32.83	8.00e-54	204.00
IUUC-Tvi-122672	Trichoderma virens	32.46	2.00e-47	183.00
IUUC-Tae-125679	Triticum aestivum	40.54	1.00e-98	353.00
IUUC-Tur-126487	Triticum urartu	40.09	1.00e-96	346.00
IUUC-Tme-127097	Tuber melanosporum	34.85	7.00e-68	251.00
IUUC-Ttr-128465	Tursiops truncatus	89.44	0.00e+00	827.00
IUUC-Uma-129645	Ustilago maydis	31.08	2.00e-64	239.00
IUUC-Vda-129989	Verticillium dahliae	28.77	8.00e-30	124.00
IUUC-Vpa-130529	Vicugna pacos	93.26	0.00e+00	862.00
IUUC-Vvi-131059	Vitis vinifera	38.65	2.00e-92	333.00
IUUC-Xtr-132002	Xenopus tropicalis	77.75	0.00e+00	755.00
IUUC-Xma-133930	Xiphophorus maculatus	71.40	0.00e+00	689.00
IUUC-Yli-134505	Yarrowia lipolytica	32.81	6.00e-58	218.00
IUUC-Zma-135895	Zea mays	42.57	2.00e-104	373.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence