iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066532

Ensembl Protein ID

ENSMPUP00000005717.1

UniProt Accession

M3Y316; M3Y316_MUSPF

Genbank Protein ID

ENSMPUP00000005717

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01062713

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000005764.1	ENSMPUT00000005816.1	ENSMPUP00000005717.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-26	91.7	153	190
UBD/Beta-Prp	8.10e-54	182.8	496	751

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsvl 98
           +++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s++
   Q: 496  RVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSIT 584
           6799*******************************************99888899****************97888999********** PP
   S: 99   slsfspsg.dklvsGshdrtirv.wdletgqcleetlsghdg...vvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +++f  ++   ++s ++d+ i      +t   l+ + + h +   +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +g +
   Q: 585  AIKFAGNRdIQMISCGADKSIYFrSAQQTSDGLHFVRTHHVAektTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGSQG-D 672
           ******885789********988644444444543333333300033346777788****************988888888888898.9 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dl 251
           ++s  ++ +d++g++l++   d+++ + d+ +gecv ++ gh++ v+ ++f+ +  +l+++s D  ++iW       ++
   Q: 673  EGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWhlgpeitNC 751
           99999999**************************************************************554433333 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAALGPGGYA RNDAVEKLPS VAVGVPMRRG QCSPPPAPPL CLRRRTRLSA APEDTVQSRV 60
SLEKVLGITA QNSSGLTCDP STGHVAYLAG CVVVILNPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCT TGGGGCCCGG AGGCTACGCG CGGAATGATG CAGTCGAGAA GCTGCCATCC 60
GTGGCGGTCG GAGTTCCGAT GAGGAGGGGC CAGTGCTCTC CACCCCCCGC TCCGCCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	92.46	0.00e+00	2700.00
IUUC-Aca-004935	Anolis carolinensis	70.85	0.00e+00	1006.00
IUUC-Ath-007624	Arabidopsis thaliana	30.65	7.00e-94	338.00
IUUC-Afu-008757	Aspergillus fumigatus	21.57	4.00e-28	120.00
IUUC-Bta-013336	Bos taurus	82.41	0.00e+00	2311.00
IUUC-Cel-018592	Caenorhabditis elegans	28.71	4.00e-74	273.00
IUUC-Cja-019094	Callithrix jacchus	80.42	0.00e+00	2318.00
IUUC-Cfa-020529	Canis familiaris	89.94	0.00e+00	2633.00
IUUC-Cpo-021970	Cavia porcellus	87.08	0.00e+00	1670.00
IUUC-Csa-024161	Chlorocebus sabaeus	81.05	0.00e+00	2270.00
IUUC-Cho-024310	Choloepus hoffmanni	85.43	0.00e+00	1174.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	23.08	4.00e-25	110.00
IUUC-Dre-028678	Danio rerio	57.08	0.00e+00	1009.00
IUUC-Dno-029933	Dasypus novemcinctus	78.84	0.00e+00	2219.00
IUUC-Dor-031147	Dipodomys ordii	77.82	0.00e+00	2125.00
IUUC-Dse-031501	Dothistroma septosporum	29.39	4.00e-22	100.00
IUUC-Eca-033675	Equus caballus	84.57	0.00e+00	2398.00
IUUC-Eeu-034798	Erinaceus europaeus	89.36	0.00e+00	903.00
IUUC-Fca-035826	Felis catus	88.95	0.00e+00	2649.00
IUUC-Gma-043644	Glycine max	31.54	7.00e-102	365.00
IUUC-Ggo-045152	Gorilla gorilla	82.87	0.00e+00	2283.00
IUUC-Hsa-045891	Homo sapiens	82.93	0.00e+00	2316.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	93.24	0.00e+00	1558.00
IUUC-Lch-049669	Latimeria chalumnae	58.58	0.00e+00	1011.00
IUUC-Loc-052488	Lepisosteus oculatus	53.58	0.00e+00	1070.00
IUUC-Laf-053992	Loxodonta africana	80.53	0.00e+00	2310.00
IUUC-Mcc-054994	Macaca mulatta	82.28	0.00e+00	2263.00
IUUC-Meu-056815	Macropus eugenii	81.50	0.00e+00	1432.00
IUUC-Mtr-058383	Medicago truncatula	30.87	8.00e-51	194.00
IUUC-Mmr-060693	Microcebus murinus	80.36	0.00e+00	2253.00
IUUC-Mdo-063007	Monodelphis domestica	61.99	0.00e+00	1807.00
IUUC-Mmu-064067	Mus musculus	75.19	0.00e+00	2157.00
IUUC-Mlu-066982	Myotis lucifugus	81.64	0.00e+00	2285.00
IUUC-Nle-070042	Nomascus leucogenys	85.08	0.00e+00	1926.00
IUUC-Opr-070397	Ochotona princeps	78.78	0.00e+00	2280.00
IUUC-Oan-073119	Ornithorhynchus anatinus	67.11	0.00e+00	876.00
IUUC-Ocu-074274	Oryctolagus cuniculus	80.95	0.00e+00	2234.00
IUUC-Oga-088577	Otolemur garnettii	82.21	0.00e+00	2374.00
IUUC-Oar-090117	Ovis aries	80.82	0.00e+00	2256.00
IUUC-Ptr-090553	Pan troglodytes	82.93	0.00e+00	2336.00
IUUC-Pan-092559	Papio anubis	73.57	0.00e+00	1095.00
IUUC-Psi-093710	Pelodiscus sinensis	65.15	0.00e+00	1399.00
IUUC-Pab-098510	Pongo abelii	81.77	0.00e+00	2220.00
IUUC-Pop-099155	Populus trichocarpa	32.00	6.00e-99	356.00
IUUC-Pca-100323	Procavia capensis	72.01	0.00e+00	1336.00
IUUC-Pva-102895	Pteropus vampyrus	85.58	0.00e+00	2467.00
IUUC-Rno-105598	Rattus norvegicus	75.91	0.00e+00	2199.00
IUUC-Sha-107013	Sarcophilus harrisii	67.39	0.00e+00	1830.00
IUUC-Smo-109134	Selaginella moellendorffii	37.21	2.00e-134	474.00
IUUC-Sar-113261	Sorex araneus	76.30	0.00e+00	2170.00
IUUC-Ssc-115317	Sus scrofa	84.07	0.00e+00	2355.00
IUUC-Tsy-118799	Tarsius syrichta	90.59	0.00e+00	855.00
IUUC-Tni-120316	Tetraodon nigroviridis	56.35	0.00e+00	789.00
IUUC-Tca-121475	Theobroma cacao	30.42	3.00e-98	353.00
IUUC-Tre-122008	Trichoderma reesei	23.35	3.00e-30	127.00
IUUC-Tvi-122281	Trichoderma virens	23.56	2.00e-30	128.00
IUUC-Tme-127128	Tuber melanosporum	23.75	5.00e-31	130.00
IUUC-Tbe-127555	Tupaia belangeri	93.42	0.00e+00	1016.00
IUUC-Ttr-128722	Tursiops truncatus	83.49	0.00e+00	2390.00
IUUC-Vda-129957	Verticillium dahliae	23.58	7.00e-31	129.00
IUUC-Vpa-130392	Vicugna pacos	71.92	2.00e-111	396.00
IUUC-Vvi-131035	Vitis vinifera	33.06	1.00e-106	380.00
IUUC-Xtr-131789	Xenopus tropicalis	60.12	0.00e+00	997.00
IUUC-Yli-134437	Yarrowia lipolytica	26.64	1.00e-16	82.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence