iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066038

Ensembl Protein ID

ENSMPUP00000005721.1

UniProt Accession

M3Y320; M3Y320_MUSPF

Genbank Protein ID

ENSMPUP00000005721

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01062534

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000005768.1	ENSMPUT00000005820.1	ENSMPUP00000005721.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-98	329.5	99	428

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 99   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 180
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ +++++ +++k + ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 181  MQQDAHEFLNYLLNTIADIL---QEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 266
           ********************...34555555555556666677788888888************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 267  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 348
           ****.....9**********************************************************************66555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts++  ++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 349  TSSDA-VNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 428
           77554.4459***************************.888*******************999*****************97 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MECGCLRKPA ARAEPGSTSG QRADPEDVSG SEVLEWSGRG GSWKTGPPGT ERADCGTAPP 60
HADGDHPDDG SRRRVKGTNA SALEKDIGPE QFPINEHYFG LVNFGNTCYC NSVLQALYFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGTGTGCC CAAAGGACAA GGTGTAGGTT GTTTGTAAGA GCCGTGGAAG TCAAGATCCC 60
TGGGCTCTAA GCTGAATAAG AAAGAAGGGG AGCGAGAGGG TCTGGGCAGC ACATGGAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	59.89	7.00e-125	440.00
IUUC-Aml-002353	Ailuropoda melanoleuca	100.00	0.00e+00	698.00
IUUC-Atr-002650	Amborella trichopoda	59.45	2.00e-124	439.00
IUUC-Apl-003380	Anas platyrhynchos	98.59	0.00e+00	687.00
IUUC-Aca-005031	Anolis carolinensis	97.18	0.00e+00	724.00
IUUC-Aly-005830	Arabidopsis lyrata	58.81	1.00e-122	432.00
IUUC-Ath-006663	Arabidopsis thaliana	58.95	2.00e-125	441.00
IUUC-Ago-007871	Ashbya gossypii	38.57	9.00e-50	191.00
IUUC-Acl-008239	Aspergillus clavatus	46.03	1.00e-74	274.00
IUUC-Afl-008602	Aspergillus flavus	48.83	2.00e-76	280.00
IUUC-Afu-008816	Aspergillus fumigatus	46.84	3.00e-74	273.00
IUUC-Ani-009137	Aspergillus nidulans	46.80	5.00e-74	272.00
IUUC-Ang-009703	Aspergillus niger	46.80	4.00e-76	279.00
IUUC-Aor-009901	Aspergillus oryzae	48.83	2.00e-76	280.00
IUUC-Ate-010431	Aspergillus terreus	48.83	1.00e-74	274.00
IUUC-Ame-010862	Astyanax mexicanus	94.68	0.00e+00	699.00
IUUC-Bgr-012071	Blumeria graminis	43.05	2.00e-73	270.00
IUUC-Bta-013023	Bos taurus	99.72	0.00e+00	699.00
IUUC-Bci-013837	Botrytis cinerea	38.70	1.00e-71	264.00
IUUC-Bdi-014008	Brachypodium distachyon	60.16	4.00e-124	437.00
IUUC-Bol-015138	Brassica oleracea	58.49	1.00e-123	436.00
IUUC-Bra-017483	Brassica rapa	60.23	3.00e-125	441.00
IUUC-Cel-018379	Caenorhabditis elegans	62.22	2.00e-144	505.00
IUUC-Cja-018956	Callithrix jacchus	98.34	0.00e+00	698.00
IUUC-Cfa-021064	Canis familiaris	99.16	0.00e+00	691.00
IUUC-Cpo-022443	Cavia porcellus	99.16	0.00e+00	697.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.52	1.00e-98	352.00
IUUC-Csa-023841	Chlorocebus sabaeus	100.00	0.00e+00	698.00
IUUC-Cho-024902	Choloepus hoffmanni	74.86	9.00e-155	539.00
IUUC-Cin-025659	Ciona intestinalis	56.50	2.00e-128	451.00
IUUC-Csv-025828	Ciona savignyi	73.89	8.00e-88	317.00
IUUC-Cgl-026611	Colletotrichum gloeosporioides	41.25	1.00e-73	271.00
IUUC-Cne-026900	Cryptococcus neoformans	41.91	4.00e-60	226.00
IUUC-Dre-028230	Danio rerio	94.15	0.00e+00	697.00
IUUC-Dno-029209	Dasypus novemcinctus	100.00	0.00e+00	696.00
IUUC-Dor-030972	Dipodomys ordii	89.02	4.00e-135	474.00
IUUC-Dse-031470	Dothistroma septosporum	47.25	3.00e-75	276.00
IUUC-Dme-032038	Drosophila melanogaster	81.28	2.00e-99	356.00
IUUC-Ete-033125	Echinops telfairi	70.41	7.00e-118	416.00
IUUC-Eca-033721	Equus caballus	99.72	0.00e+00	695.00
IUUC-Eeu-034916	Erinaceus europaeus	98.64	2.00e-162	564.00
IUUC-Fca-036299	Felis catus	99.72	0.00e+00	698.00
IUUC-Fal-037172	Ficedula albicollis	90.11	2.00e-180	624.00
IUUC-Fox-037682	Fusarium oxysporum	42.32	6.00e-74	272.00
IUUC-Fso-038299	Fusarium solani	37.07	6.00e-74	272.00
IUUC-Gmo-038611	Gadus morhua	94.63	0.00e+00	691.00
IUUC-Ggr-039806	Gaeumannomyces graminis	42.24	3.00e-75	276.00
IUUC-Gga-041157	Gallus gallus	98.59	0.00e+00	687.00
IUUC-Gac-041764	Gasterosteus aculeatus	95.21	0.00e+00	696.00
IUUC-Gma-043828	Glycine max	60.55	1.00e-126	446.00
IUUC-Ggo-044659	Gorilla gorilla	100.00	0.00e+00	696.00
IUUC-Hsa-046156	Homo sapiens	100.00	0.00e+00	698.00
IUUC-Hvu-047692	Hordeum vulgare	58.74	1.00e-122	432.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	100.00	0.00e+00	698.00
IUUC-Kpa-049250	Komagataella pastoris	44.83	7.00e-70	258.00
IUUC-Lch-049969	Latimeria chalumnae	96.61	0.00e+00	658.00
IUUC-Lpe-051368	Leersia perrieri	58.31	2.00e-121	429.00
IUUC-Loc-052479	Lepisosteus oculatus	90.96	0.00e+00	667.00
IUUC-Lma-053300	Leptosphaeria maculans	45.43	4.00e-77	282.00
IUUC-Laf-054085	Loxodonta africana	100.00	0.00e+00	698.00
IUUC-Mcc-055566	Macaca mulatta	100.00	0.00e+00	698.00
IUUC-Mor-057072	Magnaporthe oryzae	43.65	7.00e-76	278.00
IUUC-Mpo-057424	Magnaporthe poae	42.86	3.00e-75	276.00
IUUC-Mtr-057715	Medicago truncatula	60.22	7.00e-127	446.00
IUUC-Mla-059142	Melampsora laricipopulina	54.08	5.00e-96	345.00
IUUC-Mga-059575	Meleagris gallopavo	98.03	0.00e+00	687.00
IUUC-Mvi-060357	Microbotryum violaceum	53.96	1.00e-77	284.00
IUUC-Mmr-060751	Microcebus murinus	89.55	0.00e+00	666.00
IUUC-Mdo-062579	Monodelphis domestica	99.72	0.00e+00	696.00
IUUC-Mmu-063611	Mus musculus	100.00	0.00e+00	698.00
IUUC-Mac-065323	Musa acuminata	60.56	4.00e-123	434.00
IUUC-Mlu-068183	Myotis lucifugus	99.44	0.00e+00	697.00
IUUC-Nfi-068611	Neosartorya fischeri	47.49	4.00e-74	272.00
IUUC-Ncr-068699	Neurospora crassa	42.02	3.00e-73	270.00
IUUC-Nle-069330	Nomascus leucogenys	100.00	0.00e+00	698.00
IUUC-Opr-070980	Ochotona princeps	99.72	0.00e+00	696.00
IUUC-Ont-072134	Oreochromis niloticus	94.96	0.00e+00	702.00
IUUC-Oan-073583	Ornithorhynchus anatinus	93.50	0.00e+00	681.00
IUUC-Ocu-074923	Oryctolagus cuniculus	99.44	0.00e+00	694.00
IUUC-Oba-075220	Oryza barthii	59.34	6.00e-122	430.00
IUUC-Obr-076208	Oryza brachyantha	57.65	4.00e-119	421.00
IUUC-Ogl-077216	Oryza glaberrima	59.34	6.00e-122	430.00
IUUC-Ogu-078836	Oryza glumaepatula	59.34	6.00e-122	430.00
IUUC-Oin-079522	Oryza indica	59.34	6.00e-122	430.00
IUUC-Olo-080882	Oryza longistaminata	59.34	6.00e-122	430.00
IUUC-Ome-081549	Oryza meridionalis	59.34	6.00e-122	430.00
IUUC-Oni-082982	Oryza nivara	59.34	6.00e-122	430.00
IUUC-Opu-083532	Oryza punctata	59.62	2.00e-122	431.00
IUUC-Oru-084568	Oryza rufipogon	59.34	6.00e-122	430.00
IUUC-Osa-085299	Oryza sativa	59.34	6.00e-122	430.00
IUUC-Ola-086546	Oryzias latipes	94.21	0.00e+00	706.00
IUUC-Olu-087809	Ostreococcus lucimarinus	48.44	2.00e-80	292.00
IUUC-Oga-088073	Otolemur garnettii	99.72	0.00e+00	695.00
IUUC-Oar-089248	Ovis aries	96.50	0.00e+00	699.00
IUUC-Ptr-090814	Pan troglodytes	100.00	0.00e+00	698.00
IUUC-Pan-091753	Papio anubis	100.00	0.00e+00	698.00
IUUC-Psi-094012	Pelodiscus sinensis	98.87	0.00e+00	689.00
IUUC-Pma-094388	Petromyzon marinus	89.75	0.00e+00	663.00
IUUC-Pno-095044	Phaeosphaeria nodorum	45.12	4.00e-76	279.00
IUUC-Ppa-095415	Physcomitrella patens	58.92	2.00e-126	445.00
IUUC-Pfo-097369	Poecilia formosa	94.96	0.00e+00	702.00
IUUC-Pab-098594	Pongo abelii	100.00	0.00e+00	698.00
IUUC-Pop-099798	Populus trichocarpa	60.00	6.00e-126	443.00
IUUC-Pca-100913	Procavia capensis	83.90	3.00e-159	554.00
IUUC-Ppe-101474	Prunus persica	59.73	6.00e-126	443.00
IUUC-Pva-102892	Pteropus vampyrus	100.00	0.00e+00	698.00
IUUC-Pgr-103306	Puccinia graminis	53.31	2.00e-96	347.00
IUUC-Pte-104356	Pyrenophora teres	47.02	1.00e-76	281.00
IUUC-Pyt-104709	Pyrenophora triticirepentis	47.02	2.00e-76	280.00
IUUC-Rno-104909	Rattus norvegicus	99.72	0.00e+00	696.00
IUUC-Sce-106367	Saccharomyces cerevisiae	37.63	1.00e-56	214.00
IUUC-Sha-107400	Sarcophilus harrisii	99.44	0.00e+00	697.00
IUUC-Sja-107684	Schizosaccharomyces japonicus	45.24	1.00e-65	244.00
IUUC-Spo-108095	Schizosaccharomyces pombe	45.70	1.00e-74	273.00
IUUC-Smo-109064	Selaginella moellendorffii	60.22	2.00e-119	422.00
IUUC-Sit-110819	Setaria italica	58.90	2.00e-122	431.00
IUUC-Sly-111210	Solanum lycopersicum	59.62	1.00e-125	442.00
IUUC-Stu-112398	Solanum tuberosum	60.06	9.00e-126	443.00
IUUC-Sar-113216	Sorex araneus	89.27	0.00e+00	658.00
IUUC-Sbi-114562	Sorghum bicolor	58.90	4.00e-123	434.00
IUUC-Sre-115197	Sporisorium reilianum	48.75	1.00e-79	291.00
IUUC-Ssc-115550	Sus scrofa	100.00	0.00e+00	697.00
IUUC-Tgu-116800	Taeniopygia guttata	98.59	0.00e+00	687.00
IUUC-Tru-118212	Takifugu rubripes	94.96	0.00e+00	704.00
IUUC-Tsy-119520	Tarsius syrichta	79.22	4.00e-115	407.00
IUUC-Tni-120071	Tetraodon nigroviridis	94.96	0.00e+00	705.00
IUUC-Tca-121329	Theobroma cacao	60.00	4.00e-126	444.00
IUUC-Tre-122226	Trichoderma reesei	42.32	1.00e-73	271.00
IUUC-Tvi-122330	Trichoderma virens	43.57	3.00e-74	273.00
IUUC-Tae-124807	Triticum aestivum	59.89	5.00e-125	440.00
IUUC-Tur-126563	Triticum urartu	59.89	5.00e-125	440.00
IUUC-Tme-126890	Tuber melanosporum	46.49	6.00e-90	325.00
IUUC-Tbe-127783	Tupaia belangeri	88.42	0.00e+00	646.00
IUUC-Ttr-129083	Tursiops truncatus	89.27	0.00e+00	664.00
IUUC-Uma-129409	Ustilago maydis	49.13	3.00e-81	296.00
IUUC-Vda-129736	Verticillium dahliae	37.66	1.00e-56	214.00
IUUC-Vpa-130590	Vicugna pacos	95.20	0.00e+00	650.00
IUUC-Vvi-131371	Vitis vinifera	59.73	7.00e-126	443.00
IUUC-Xtr-132082	Xenopus tropicalis	90.68	0.00e+00	668.00
IUUC-Xma-133111	Xiphophorus maculatus	94.96	0.00e+00	702.00
IUUC-Yli-134632	Yarrowia lipolytica	44.86	6.00e-79	288.00
IUUC-Zma-134951	Zea mays	59.07	8.00e-123	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence