iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pop-099654

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

WD-40 repeat family protein

Genbank Nucleotide ID

CM000352

Gene Name

POPTRDRAFT_257786; POPTR_0016s12590g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0016s12590	POPTR_0016s12590.1	POPTR_0016s12590.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-25	88.6	316	355
E3 adaptor/Cullin RING/APC_C/CDC20	1.00e-122	410.4	132	437

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGs..dDgtikvWDlrtgvll 36
           Ht+ v +la+   +++ll+sG+  +D +ik W+++tg +l
   Q: 316  HTSAVKALAWcpfQGNLLASGGggGDRSIKFWNTHTGACL 355
           9**********98669****5555*************997 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrt 91
           e+ ldap+l ddfylnLldW+sknvla+aL+++vylw+a++g+ s+l  + +e   vtsv+w ++g +la+G ++++v+++D +++k++r+
   Q: 132  ERTLDAPDLVDDFYLNLLDWGSKNVLAIALENTVYLWDASNGSTSELVTVgDEVGPVTSVNWAPDGLHLAIGLNNSNVQLWDSASCKQLRN 222
           689***********************************************99999************************************ PP
   S: 92   l.tghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse......Plkkf 175
           l   h +rvg+++Wn+++l++G+ dg+i  +dvr++ + ++t+++h+qevCGlkw+ ++++LasGGnDn +++wd s  +        ++ 
   Q: 223  LrGCHRSRVGSMAWNNHILTTGGMDGKIINNDVRIRSHIVETYRGHQQEVCGLKWSASGQQLASGGNDNIIHIWDRSVASsnsatqWFHRL 313
           *55699*********************************************************************8755545555456677 PP
   S: 176  kehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           +eh++avka+aw+P+q +lLasGGG  Dr ikfwnt tga+l++idtgsqvc llw k+++el+s+hGf++n+++lwkyps+ k+ael+gh
   Q: 314  EEHTSAVKALAWCPFQGNLLASGGGGGDRSIKFWNTHTGACLNSIDTGSQVCALLWNKNERELLSSHGFTQNQLVLWKYPSMLKMAELTGH 404
           8****************************************************************************************** PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfdk 299
           ++Rvl++a spdg +++taagDetlrfw++f  
   Q: 405  TSRVLYMAQSPDGCTVATAAGDETLRFWNVFGV 437
           ******************************975 PP

Organism

Populus trichocarpa

Protein Sequence
(Fasta)

MDAGSLNSSS YMKAQSRFPL QEQFLHRKNS KDNLDRFIPN RSAMDLDYAH YMLTQGRKGG 60
KENPTATVNS PSREAYRKQL AEALNLNRTR ILAFKNKPPT PVELIPRDHL SSSLHYQAKP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGCAG GATCTTTGAA CTCTTCTTCA TACATGAAAG CACAATCCCG GTTCCCCCTC 60
CAAGAACAGT TTCTTCATAG AAAGAATTCT AAAGATAACG TAAGATTCTT CAATTTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

pop:POPTR_0016s12590g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001545	Ailuropoda melanoleuca	45.65	5.00e-101	360.00
IUUC-Bta-012625	Bos taurus	45.35	3.00e-101	361.00
IUUC-Cja-019132	Callithrix jacchus	46.88	1.00e-103	369.00
IUUC-Cfa-020780	Canis familiaris	45.89	8.00e-102	363.00
IUUC-Cpo-022223	Cavia porcellus	46.14	2.00e-92	332.00
IUUC-Csa-023666	Chlorocebus sabaeus	46.38	2.00e-102	365.00
IUUC-Dno-028865	Dasypus novemcinctus	46.10	9.00e-99	353.00
IUUC-Dor-030958	Dipodomys ordii	46.38	1.00e-97	349.00
IUUC-Ete-032387	Echinops telfairi	42.28	1.00e-91	329.00
IUUC-Eeu-035059	Erinaceus europaeus	41.06	3.00e-84	305.00
IUUC-Fca-036346	Felis catus	44.24	1.00e-88	319.00
IUUC-Gac-041431	Gasterosteus aculeatus	44.39	2.00e-97	348.00
IUUC-Ggo-045052	Gorilla gorilla	46.14	2.00e-102	365.00
IUUC-Hsa-046305	Homo sapiens	46.14	2.00e-102	365.00
IUUC-Hvu-047565	Hordeum vulgare	73.72	0.00e+00	660.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	46.38	2.00e-93	335.00
IUUC-Laf-053742	Loxodonta africana	45.65	2.00e-100	358.00
IUUC-Mcc-054948	Macaca mulatta	46.38	2.00e-102	365.00
IUUC-Mmr-061615	Microcebus murinus	46.63	2.00e-102	365.00
IUUC-Mmu-063864	Mus musculus	46.38	2.00e-97	348.00
IUUC-Mpu-066502	Mustela putorius furo	45.74	1.00e-103	369.00
IUUC-Mlu-067277	Myotis lucifugus	45.41	4.00e-99	354.00
IUUC-Nle-070149	Nomascus leucogenys	46.14	1.00e-100	359.00
IUUC-Oan-073677	Ornithorhynchus anatinus	52.04	9.00e-96	343.00
IUUC-Ocu-073797	Oryctolagus cuniculus	46.63	1.00e-102	366.00
IUUC-Oga-088184	Otolemur garnettii	45.54	5.00e-99	354.00
IUUC-Oar-090023	Ovis aries	45.61	2.00e-98	352.00
IUUC-Ptr-090935	Pan troglodytes	45.97	6.00e-101	360.00
IUUC-Pan-091845	Papio anubis	46.38	2.00e-102	365.00
IUUC-Pno-094809	Phaeosphaeria nodorum	42.55	2.00e-95	342.00
IUUC-Pab-098603	Pongo abelii	46.63	1.00e-102	366.00
IUUC-Pca-101062	Procavia capensis	44.98	7.00e-102	363.00
IUUC-Ppe-101865	Prunus persica	84.10	0.00e+00	749.00
IUUC-Pva-102925	Pteropus vampyrus	46.70	9.00e-103	366.00
IUUC-Rno-106005	Rattus norvegicus	45.63	6.00e-97	347.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	48.63	4.00e-95	341.00
IUUC-Sar-113092	Sorex araneus	45.30	1.00e-91	329.00
IUUC-Ssc-115710	Sus scrofa	46.14	1.00e-101	363.00
IUUC-Tca-120949	Theobroma cacao	85.40	0.00e+00	818.00
IUUC-Tbe-127384	Tupaia belangeri	49.64	2.00e-82	298.00
IUUC-Ttr-128511	Tursiops truncatus	45.89	6.00e-102	363.00
IUUC-Xma-133332	Xiphophorus maculatus	46.27	2.00e-102	365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence