iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022112

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02057168

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000002364.3	ENSCPOT00000002397.2	ENSCPOP00000002149.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.41	0.00e+00	868.00	IUUC-Hsa-045784
E3 activity/RING/RING	27.54	4.00e-28	120.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS TEPGPQPHRP LDPLTVHSAY ERAGAVPRTP LSGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG AGCTGGTGGA GGCCAAAGTG AGTGAGCGGC GGCCGCGCCG GCCGGGCAGG 60
GCCGGGCGGG GAACGGGGCG GGGCTCGGGC CGCGAGCCGA GGTCTGTGGC TCCCGCCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	88.41	0.00e+00	867.00
IUUC-Apl-003765	Anas platyrhynchos	84.07	0.00e+00	815.00
IUUC-Ame-010763	Astyanax mexicanus	59.02	3.00e-145	508.00
IUUC-Bta-012369	Bos taurus	90.08	0.00e+00	887.00
IUUC-Cja-019450	Callithrix jacchus	88.52	0.00e+00	887.00
IUUC-Cfa-020933	Canis familiaris	89.71	0.00e+00	876.00
IUUC-Csa-023913	Chlorocebus sabaeus	77.03	0.00e+00	716.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	27.30	2.00e-32	133.00
IUUC-Dre-027609	Danio rerio	58.50	1.00e-140	492.00
IUUC-Dno-029664	Dasypus novemcinctus	72.97	2.00e-152	533.00
IUUC-Ete-032988	Echinops telfairi	91.80	5.00e-172	597.00
IUUC-Eca-034430	Equus caballus	85.96	0.00e+00	858.00
IUUC-Fca-035968	Felis catus	95.21	8.00e-166	575.00
IUUC-Fal-037449	Ficedula albicollis	80.47	0.00e+00	791.00
IUUC-Fso-038103	Fusarium solani	34.72	1.00e-26	114.00
IUUC-Gmo-038925	Gadus morhua	61.52	5.00e-139	487.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.48	4.00e-29	122.00
IUUC-Gga-040362	Gallus gallus	82.85	0.00e+00	843.00
IUUC-Gac-042353	Gasterosteus aculeatus	58.96	3.00e-132	465.00
IUUC-Ggo-044810	Gorilla gorilla	86.96	0.00e+00	850.00
IUUC-Hsa-045784	Homo sapiens	89.30	0.00e+00	899.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	89.29	0.00e+00	876.00
IUUC-Lch-049727	Latimeria chalumnae	70.90	2.00e-150	525.00
IUUC-Loc-052354	Lepisosteus oculatus	53.50	1.00e-121	429.00
IUUC-Laf-054261	Loxodonta africana	88.74	0.00e+00	893.00
IUUC-Mcc-054931	Macaca mulatta	88.91	0.00e+00	883.00
IUUC-Meu-056468	Macropus eugenii	83.30	0.00e+00	859.00
IUUC-Mpo-057405	Magnaporthe poae	33.06	1.00e-28	121.00
IUUC-Mtr-058267	Medicago truncatula	35.14	5.00e-19	90.10
IUUC-Mla-058882	Melampsora laricipopulina	36.18	6.00e-23	102.00
IUUC-Mga-059981	Meleagris gallopavo	88.57	0.00e+00	707.00
IUUC-Mvi-060421	Microbotryum violaceum	28.79	1.00e-26	115.00
IUUC-Mmr-061181	Microcebus murinus	85.85	0.00e+00	840.00
IUUC-Mdo-062345	Monodelphis domestica	83.50	0.00e+00	858.00
IUUC-Mmu-063197	Mus musculus	85.99	0.00e+00	847.00
IUUC-Mpu-066275	Mustela putorius furo	88.13	0.00e+00	879.00
IUUC-Mlu-067194	Myotis lucifugus	89.53	0.00e+00	886.00
IUUC-Ncr-068929	Neurospora crassa	27.36	5.00e-27	115.00
IUUC-Ont-072227	Oreochromis niloticus	58.50	2.00e-137	482.00
IUUC-Oba-075731	Oryza barthii	43.81	4.00e-21	97.10
IUUC-Obr-076179	Oryza brachyantha	43.81	7.00e-21	95.90
IUUC-Ogl-077808	Oryza glaberrima	43.81	4.00e-21	97.10
IUUC-Ogu-078271	Oryza glumaepatula	43.81	4.00e-21	97.10
IUUC-Oin-079070	Oryza indica	43.81	3.00e-21	97.10
IUUC-Oru-084716	Oryza rufipogon	43.81	3.00e-21	97.10
IUUC-Ola-086865	Oryzias latipes	60.88	2.00e-136	479.00
IUUC-Oga-088945	Otolemur garnettii	89.49	0.00e+00	902.00
IUUC-Oar-089412	Ovis aries	87.11	0.00e+00	847.00
IUUC-Ptr-091550	Pan troglodytes	84.21	0.00e+00	635.00
IUUC-Pan-092183	Papio anubis	88.72	0.00e+00	897.00
IUUC-Psi-093003	Pelodiscus sinensis	81.09	0.00e+00	826.00
IUUC-Pfo-096704	Poecilia formosa	58.92	5.00e-140	491.00
IUUC-Pab-097923	Pongo abelii	96.59	0.00e+00	764.00
IUUC-Pca-100249	Procavia capensis	75.56	1.00e-142	499.00
IUUC-Pva-102562	Pteropus vampyrus	84.29	0.00e+00	824.00
IUUC-Rno-105762	Rattus norvegicus	86.58	0.00e+00	853.00
IUUC-Sce-106398	Saccharomyces cerevisiae	33.53	7.00e-28	119.00
IUUC-Sha-107253	Sarcophilus harrisii	82.72	0.00e+00	849.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.41	6.00e-29	122.00
IUUC-Smo-109174	Selaginella moellendorffii	37.17	3.00e-14	74.30
IUUC-Sar-113149	Sorex araneus	86.94	1.00e-128	453.00
IUUC-Ssc-115241	Sus scrofa	90.08	0.00e+00	896.00
IUUC-Tgu-116884	Taeniopygia guttata	81.03	0.00e+00	791.00
IUUC-Tru-118031	Takifugu rubripes	58.96	8.00e-144	503.00
IUUC-Tni-119766	Tetraodon nigroviridis	58.96	6.00e-139	487.00
IUUC-Ttr-128556	Tursiops truncatus	82.31	0.00e+00	728.00
IUUC-Vda-129985	Verticillium dahliae	33.80	2.00e-30	126.00
IUUC-Xtr-131866	Xenopus tropicalis	74.81	0.00e+00	757.00
IUUC-Xma-133963	Xiphophorus maculatus	58.69	2.00e-134	472.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence