iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067194

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02052795

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000008650.2	ENSMLUT00000008650.2	ENSMLUP00000007884.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.79	0.00e+00	903.00	IUUC-Hsa-045784
E3 activity/RING/RING	34.10	2.00e-28	121.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS SEPVSQPHRP LDPLTMHSTY ERASTVPRTP LTGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGTGGCC AAGATGGCGG CGGAGCTGGT GGAGGCCAAA GTGAGTGAGC GGCGGCNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	93.74	0.00e+00	889.00
IUUC-Apl-003765	Anas platyrhynchos	82.35	0.00e+00	820.00
IUUC-Ame-010763	Astyanax mexicanus	59.38	4.00e-145	507.00
IUUC-Bta-012369	Bos taurus	97.09	0.00e+00	924.00
IUUC-Cja-019450	Callithrix jacchus	92.62	0.00e+00	890.00
IUUC-Cfa-020933	Canis familiaris	95.16	0.00e+00	905.00
IUUC-Cpo-022112	Cavia porcellus	92.86	0.00e+00	855.00
IUUC-Csa-023913	Chlorocebus sabaeus	80.35	0.00e+00	725.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	28.92	3.00e-36	145.00
IUUC-Dre-027609	Danio rerio	59.32	2.00e-141	495.00
IUUC-Dno-029664	Dasypus novemcinctus	74.70	3.00e-153	535.00
IUUC-Ete-032988	Echinops telfairi	91.54	2.00e-169	588.00
IUUC-Eca-034430	Equus caballus	90.27	0.00e+00	878.00
IUUC-Fca-035968	Felis catus	96.94	1.00e-167	582.00
IUUC-Fal-037449	Ficedula albicollis	83.53	0.00e+00	812.00
IUUC-Fso-038103	Fusarium solani	34.72	7.00e-27	114.00
IUUC-Gmo-038925	Gadus morhua	61.22	2.00e-138	485.00
IUUC-Ggr-039896	Gaeumannomyces graminis	31.71	1.00e-29	124.00
IUUC-Gga-040362	Gallus gallus	85.27	0.00e+00	851.00
IUUC-Gac-042353	Gasterosteus aculeatus	59.09	8.00e-133	466.00
IUUC-Ggo-044810	Gorilla gorilla	91.46	0.00e+00	857.00
IUUC-Hsa-045784	Homo sapiens	93.79	0.00e+00	902.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	90.93	0.00e+00	872.00
IUUC-Lch-049727	Latimeria chalumnae	71.58	5.00e-151	526.00
IUUC-Loc-052354	Lepisosteus oculatus	67.58	2.00e-101	362.00
IUUC-Laf-054261	Loxodonta africana	93.04	0.00e+00	907.00
IUUC-Mcc-054931	Macaca mulatta	91.84	0.00e+00	889.00
IUUC-Meu-056468	Macropus eugenii	87.79	0.00e+00	872.00
IUUC-Mpo-057405	Magnaporthe poae	33.62	1.00e-28	121.00
IUUC-Mtr-058267	Medicago truncatula	33.33	3.00e-18	87.00
IUUC-Mla-058882	Melampsora laricipopulina	36.84	5.00e-23	102.00
IUUC-Mga-059981	Meleagris gallopavo	88.37	0.00e+00	702.00
IUUC-Mvi-060421	Microbotryum violaceum	28.57	2.00e-27	117.00
IUUC-Mmr-061181	Microcebus murinus	90.71	0.00e+00	852.00
IUUC-Mdo-062345	Monodelphis domestica	87.40	0.00e+00	869.00
IUUC-Mmu-063197	Mus musculus	86.46	0.00e+00	837.00
IUUC-Mpu-066275	Mustela putorius furo	93.60	0.00e+00	900.00
IUUC-Ncr-068929	Neurospora crassa	32.29	2.00e-26	114.00
IUUC-Ont-072227	Oreochromis niloticus	59.09	3.00e-138	484.00
IUUC-Obr-076179	Oryza brachyantha	32.58	2.00e-20	94.70
IUUC-Oin-079070	Oryza indica	42.86	1.00e-20	95.50
IUUC-Oru-084716	Oryza rufipogon	42.86	1.00e-20	95.50
IUUC-Ola-086865	Oryzias latipes	60.58	9.00e-136	476.00
IUUC-Oga-088945	Otolemur garnettii	93.40	0.00e+00	906.00
IUUC-Oar-089412	Ovis aries	93.97	0.00e+00	878.00
IUUC-Ptr-091550	Pan troglodytes	84.82	0.00e+00	639.00
IUUC-Pan-092183	Papio anubis	93.01	0.00e+00	904.00
IUUC-Psi-093003	Pelodiscus sinensis	83.72	0.00e+00	833.00
IUUC-Pfo-096704	Poecilia formosa	58.92	3.00e-140	491.00
IUUC-Pab-097923	Pongo abelii	97.13	0.00e+00	760.00
IUUC-Pca-100249	Procavia capensis	77.26	2.00e-144	504.00
IUUC-Pva-102562	Pteropus vampyrus	91.90	0.00e+00	853.00
IUUC-Rno-105762	Rattus norvegicus	87.23	0.00e+00	842.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	1.00e-28	121.00
IUUC-Sha-107253	Sarcophilus harrisii	86.63	0.00e+00	860.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.05	7.00e-30	125.00
IUUC-Sar-113149	Sorex araneus	84.81	1.00e-125	442.00
IUUC-Ssc-115241	Sus scrofa	96.31	0.00e+00	929.00
IUUC-Tgu-116884	Taeniopygia guttata	83.30	0.00e+00	801.00
IUUC-Tru-118031	Takifugu rubripes	59.55	4.00e-144	504.00
IUUC-Tni-119766	Tetraodon nigroviridis	59.55	2.00e-139	488.00
IUUC-Ttr-128556	Tursiops truncatus	86.03	0.00e+00	743.00
IUUC-Vda-129985	Verticillium dahliae	33.90	2.00e-31	130.00
IUUC-Xtr-131866	Xenopus tropicalis	75.53	0.00e+00	756.00
IUUC-Xma-133963	Xiphophorus maculatus	59.18	4.00e-134	471.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence