iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089412

Ensembl Protein ID

ENSOARP00000011783.1

UniProt Accession

W5PMV8; W5PMV8_SHEEP

Genbank Protein ID

ENSOARP00000011783

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01091600

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010988.1	ENSOART00000011955.1	ENSOARP00000011783.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.99	0.00e+00	869.00	IUUC-Hsa-045784
E3 activity/RING/RING	27.42	4.00e-28	120.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

CVSVVALPQN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS SEPVPQPHRP LDPLTMHSTY ERASSVPRTP LTGPNIDYPV LYGKYLNGLG 120

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Nucleotide Sequence
(Fasta)

TGTGTGTCTG TGGTTGCTCT TCCCCAGAAC ATGGTGATGA GTTTCCGAGT CTCCGACCTT 60
CAGATGCTCC TGGGTTTTGT CGGCCGGAGT AAGAGTGGAC TTAAACATGA ACTTGTCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	92.35	0.00e+00	880.00
IUUC-Apl-003765	Anas platyrhynchos	91.27	0.00e+00	796.00
IUUC-Ame-010763	Astyanax mexicanus	61.67	2.00e-141	495.00
IUUC-Bta-012369	Bos taurus	93.55	0.00e+00	892.00
IUUC-Cja-019450	Callithrix jacchus	91.21	0.00e+00	862.00
IUUC-Cfa-020933	Canis familiaris	91.41	0.00e+00	873.00
IUUC-Cpo-022112	Cavia porcellus	88.35	0.00e+00	826.00
IUUC-Csa-023913	Chlorocebus sabaeus	79.65	0.00e+00	697.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	28.47	3.00e-35	143.00
IUUC-Dre-027609	Danio rerio	61.90	5.00e-138	484.00
IUUC-Dno-029664	Dasypus novemcinctus	71.98	6.00e-147	514.00
IUUC-Ete-032988	Echinops telfairi	91.91	8.00e-167	580.00
IUUC-Eca-034430	Equus caballus	88.44	0.00e+00	861.00
IUUC-Fca-035968	Felis catus	97.60	3.00e-169	587.00
IUUC-Fal-037449	Ficedula albicollis	81.55	0.00e+00	789.00
IUUC-Fso-038103	Fusarium solani	34.72	9.00e-27	114.00
IUUC-Gmo-038925	Gadus morhua	60.90	4.00e-135	474.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.48	2.00e-29	124.00
IUUC-Gga-040362	Gallus gallus	82.85	0.00e+00	814.00
IUUC-Gac-042353	Gasterosteus aculeatus	61.40	9.00e-129	453.00
IUUC-Ggo-044810	Gorilla gorilla	90.23	0.00e+00	831.00
IUUC-Hsa-045784	Homo sapiens	91.99	0.00e+00	872.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	88.39	0.00e+00	862.00
IUUC-Lch-049727	Latimeria chalumnae	71.02	3.00e-152	531.00
IUUC-Laf-054261	Loxodonta africana	90.04	0.00e+00	868.00
IUUC-Mcc-054931	Macaca mulatta	91.21	0.00e+00	860.00
IUUC-Meu-056468	Macropus eugenii	84.99	0.00e+00	834.00
IUUC-Mpo-057405	Magnaporthe poae	33.06	1.00e-28	121.00
IUUC-Mga-059981	Meleagris gallopavo	89.30	0.00e+00	706.00
IUUC-Mvi-060421	Microbotryum violaceum	29.07	3.00e-27	117.00
IUUC-Mmr-061181	Microcebus murinus	89.02	0.00e+00	838.00
IUUC-Mdo-062345	Monodelphis domestica	84.60	0.00e+00	833.00
IUUC-Mmu-063197	Mus musculus	85.55	0.00e+00	811.00
IUUC-Mpu-066275	Mustela putorius furo	92.25	0.00e+00	875.00
IUUC-Mlu-067194	Myotis lucifugus	93.97	0.00e+00	881.00
IUUC-Ncr-068929	Neurospora crassa	27.70	3.00e-27	116.00
IUUC-Ont-072227	Oreochromis niloticus	61.40	2.00e-134	472.00
IUUC-Obr-076179	Oryza brachyantha	32.58	2.00e-20	94.70
IUUC-Ola-086865	Oryzias latipes	59.46	6.00e-133	467.00
IUUC-Oga-088945	Otolemur garnettii	91.41	0.00e+00	874.00
IUUC-Ptr-091550	Pan troglodytes	86.25	0.00e+00	638.00
IUUC-Pan-092183	Papio anubis	91.02	0.00e+00	870.00
IUUC-Psi-093003	Pelodiscus sinensis	81.57	0.00e+00	810.00
IUUC-Pfo-096704	Poecilia formosa	61.90	7.00e-137	480.00
IUUC-Pab-097923	Pongo abelii	97.86	0.00e+00	751.00
IUUC-Pca-100249	Procavia capensis	74.73	8.00e-139	486.00
IUUC-Pva-102562	Pteropus vampyrus	89.24	0.00e+00	824.00
IUUC-Rno-105762	Rattus norvegicus	85.55	0.00e+00	813.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	2.00e-28	120.00
IUUC-Sha-107253	Sarcophilus harrisii	84.80	0.00e+00	833.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.27	7.00e-29	122.00
IUUC-Sar-113149	Sorex araneus	85.00	8.00e-123	433.00
IUUC-Ssc-115241	Sus scrofa	94.14	0.00e+00	886.00
IUUC-Tgu-116884	Taeniopygia guttata	83.07	0.00e+00	796.00
IUUC-Tru-118031	Takifugu rubripes	61.90	3.00e-140	491.00
IUUC-Tni-119766	Tetraodon nigroviridis	61.90	1.00e-135	476.00
IUUC-Ttr-128556	Tursiops truncatus	82.94	0.00e+00	732.00
IUUC-Xtr-131866	Xenopus tropicalis	74.81	0.00e+00	739.00
IUUC-Xma-133963	Xiphophorus maculatus	61.90	3.00e-130	458.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence