iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071928

Ensembl Protein ID

ENSONIP00000019376.1

UniProt Accession

I3KE31; I3KE31_ORENI

Genbank Protein ID

ENSONIP00000019376

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01038292

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000015401.1	ENSONIT00000019393.1	ENSONIP00000019376.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-52	171.9	104	143
UBD/Beta-Prp	1.30e-126	422.2	59	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           gHt ++ claf  d  +l+s + D  +t+ +W++++g+ l
   Q: 104  GHTHGIACLAFsADgQRLASVGLDakNTVCIWEWKRGKIL 143
           8***********5569******9999********999876 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ i+ ++ +p++sl+atg  ++d  + vwd++t ++++ l  gh+ +++++ fs dg+ l++++ D  +t+++w+ + gk++ t 
   Q: 59   GHNDDIIS-LALHPERSLVATGqvGKDPYVCVWDTFTAQTVSLLrDGHTHGIACLAFSADGQRLASVGLDakNTVCIWEWKRGKILATA 146
           68888888.9999********95558999***************99******************************************* PP
   S: 91   kghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++ ++ ++p ++++lvs + ++ i+ w l  +    +     ++g  +++ cv++ + +++  sG+l++ + +W+    +l+rt
   Q: 147  TGHSDRIFDICWDPfQQSRLVSCG-VKHIKFWSLCGNALTPKrgifGKAGDLQTILCVASAK-DDITYSGALNGDIYVWKG--LNLIRT 231
           **************8889999998.9********9999999999555555555555555554.5999************66..99**** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlq.....tgecvrtlnghtdnvksvrfspnderlvsgssDg 244
            +++h   + s+   ++   +++g++dg ++lwd+      + +  ++ +g++    +   + + +r++ g++D 
   Q: 232  VQSAHSAGIFSMYSCEE--GFATGGRDGCIRLWDVDfkpitKIDLREAEQGYKGLSIRSVCW-RADRILAGTQDS 303
           ************99996..5**************9966663222233333333333333333.555666666665 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MSDRSAPGCR LRLDWVYGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR EHSQRFYLGH 60
NDDIISLALH PERSLVATGQ VGKDPYVCVW DTFTAQTVSL LRDGHTHGIA CLAFSADGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGACC GGAGCGCCCC GGGCTGCCGG CTCAGACTGG ACTGGGTCTA CGGGTACCGG 60
GGGCACCAGT GCCGGAATAA CCTGTACTAC ACGGCGGGGA AGGAGGTGGT GTACTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	79.64	0.00e+00	3224.00
IUUC-Apl-003604	Anas platyrhynchos	79.70	0.00e+00	3198.00
IUUC-Aca-004572	Anolis carolinensis	77.69	0.00e+00	3152.00
IUUC-Ame-010713	Astyanax mexicanus	77.53	0.00e+00	3137.00
IUUC-Bta-012812	Bos taurus	79.48	0.00e+00	3215.00
IUUC-Cja-019191	Callithrix jacchus	79.31	0.00e+00	3186.00
IUUC-Cfa-020041	Canis familiaris	79.63	0.00e+00	2994.00
IUUC-Csa-023689	Chlorocebus sabaeus	79.23	0.00e+00	3115.00
IUUC-Cho-025038	Choloepus hoffmanni	78.95	0.00e+00	1222.00
IUUC-Cin-025205	Ciona intestinalis	61.09	0.00e+00	2506.00
IUUC-Csv-026014	Ciona savignyi	60.91	0.00e+00	2494.00
IUUC-Dno-029982	Dasypus novemcinctus	78.28	0.00e+00	3076.00
IUUC-Eca-034161	Equus caballus	78.42	0.00e+00	3080.00
IUUC-Fca-036307	Felis catus	79.89	0.00e+00	3230.00
IUUC-Fal-037332	Ficedula albicollis	79.32	0.00e+00	3172.00
IUUC-Gmo-039057	Gadus morhua	73.17	0.00e+00	2923.00
IUUC-Gac-042040	Gasterosteus aculeatus	88.05	0.00e+00	3382.00
IUUC-Ggo-045107	Gorilla gorilla	79.64	0.00e+00	3222.00
IUUC-Hsa-046482	Homo sapiens	79.84	0.00e+00	3224.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	78.51	0.00e+00	3127.00
IUUC-Loc-052642	Lepisosteus oculatus	82.96	0.00e+00	3314.00
IUUC-Laf-053649	Loxodonta africana	78.24	0.00e+00	3137.00
IUUC-Meu-056618	Macropus eugenii	66.69	0.00e+00	1525.00
IUUC-Mga-059202	Meleagris gallopavo	78.86	0.00e+00	3100.00
IUUC-Mmr-060729	Microcebus murinus	78.34	0.00e+00	3218.00
IUUC-Mdo-062462	Monodelphis domestica	79.18	0.00e+00	3117.00
IUUC-Mmu-063865	Mus musculus	78.93	0.00e+00	3221.00
IUUC-Mpu-066724	Mustela putorius furo	79.74	0.00e+00	3226.00
IUUC-Mlu-067816	Myotis lucifugus	79.89	0.00e+00	3238.00
IUUC-Opr-070213	Ochotona princeps	78.09	0.00e+00	1684.00
IUUC-Oan-073563	Ornithorhynchus anatinus	79.44	0.00e+00	3203.00
IUUC-Ocu-074531	Oryctolagus cuniculus	79.89	0.00e+00	3228.00
IUUC-Ola-086943	Oryzias latipes	89.77	0.00e+00	3488.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.30	6.00e-118	418.00
IUUC-Oga-088665	Otolemur garnettii	79.13	0.00e+00	3112.00
IUUC-Oar-090429	Ovis aries	79.64	0.00e+00	3220.00
IUUC-Psi-093281	Pelodiscus sinensis	79.03	0.00e+00	3182.00
IUUC-Pma-094424	Petromyzon marinus	70.57	2.00e-120	424.00
IUUC-Pfo-096687	Poecilia formosa	85.04	0.00e+00	3353.00
IUUC-Rno-105002	Rattus norvegicus	79.13	0.00e+00	3233.00
IUUC-Sha-107105	Sarcophilus harrisii	77.03	0.00e+00	3008.00
IUUC-Ssc-116282	Sus scrofa	79.33	0.00e+00	3123.00
IUUC-Tgu-116807	Taeniopygia guttata	79.54	0.00e+00	3190.00
IUUC-Tru-118040	Takifugu rubripes	76.52	0.00e+00	3100.00
IUUC-Tni-120118	Tetraodon nigroviridis	75.11	0.00e+00	3096.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence