iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011237

Ensembl Protein ID

ENSAMXP00000005568.1

UniProt Accession

W5KDA7; W5KDA7_ASTMX

Genbank Protein ID

ENSAMXP00000005568

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01026517

Gene Name

KIF21B (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000005434.1	ENSAMXT00000005568.1	ENSAMXP00000005568.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-23	81.7	1246	1280
UBD/Beta-Prp	1.00e-47	163.0	1241	1477

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt    c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1246 GHTKALMCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1280
           56666667765569****************99976 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdle.tgqcle 130
           + + +gh+++  +v+  +d  +l tgs+Drt kvw+l tg+ +++l +h +sv+s++++ s  + vs+s   +i+vwd++ + +c++
   Q: 1241 VYTAEGHTKALMCVDSTDD--LLFTGSKDRTCKVWNLVTGQEIMSLGEHPSSVVSVKYCSSLVFTVSTS---YIKVWDIRdSAKCIR 1322
           5567889988888888888..9**************************************777777777...*******83467787 PP
   S: 131  e......................tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.. 192
           +                      +  g+++ +n ++++p+g +++++++  + vr+Wdl++     +ltg h ++v +l++d+ g  
   Q: 1323 TltssgqvsqgdscaamgnravaIPPGENQ-INQIALNPSGtFMYAAAG--NSVRMWDLRRFVSTGKLTG-HLGPVMCLAVDQLGss 1405
           7*********************88888885.667778886657766665..69****************9.*********7776666 PP
   S: 193  .kelvsgsldgtvklwdlq...tgecvrtln...ghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
              +++gs+d  +k++d+    +g++  t n   +h+d +  +  +  ++ l+s++ D  i+ Wdl  ++l ++
   Q: 1406 qDVVITGSKDHNIKMFDVVegaQGSITSTHNfepAHRDGMEALSIH--GDSLYSAGRDHCIKKWDLSRKQLQQQ 1477
           58899**************666444444433223688888877777..******************99998776 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MSGGQDESSV RVALRIRPQL AKEKIEGCHI CTFVTPGEPQ VVLGKDKAFT YDYVFDMDSQ 60
QDAIYSNCTE KLIEGCFEGY NATVFAYGQT GSGKTYTMGT GFDVSISEDE CGIIPRAVTH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGTCTGGTG ACGGTCTCAT CGTCACGCAA GGACAAATGA ACGCTGCTGA GCGCTGCTGA 60
GACAGGCTTG AGCGGCCGCT GCCTGTGCAG GGGGAGGACC GGGCCGGTGG AAATGTAACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018402	Caenorhabditis elegans	37.46	0.00e+00	646.00
IUUC-Cja-019385	Callithrix jacchus	68.40	0.00e+00	1502.00
IUUC-Fca-036197	Felis catus	62.48	0.00e+00	1188.00
IUUC-Mga-059283	Meleagris gallopavo	64.77	0.00e+00	1898.00
IUUC-Mdo-062688	Monodelphis domestica	67.24	0.00e+00	1295.00
IUUC-Ont-071717	Oreochromis niloticus	72.95	0.00e+00	2113.00
IUUC-Ocu-074302	Oryctolagus cuniculus	65.43	0.00e+00	1998.00
IUUC-Ola-087491	Oryzias latipes	70.90	0.00e+00	2046.00
IUUC-Tru-117904	Takifugu rubripes	71.20	0.00e+00	2177.00
IUUC-Xtr-132829	Xenopus tropicalis	68.45	0.00e+00	2100.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence