iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059446

Ensembl Protein ID

ENSMGAP00000015520.2

UniProt Accession

G1NP79; G1NP79_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000014650.2	ENSMGAT00000016477.2	ENSMGAP00000015520.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.00e-18	66.2	32	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lv+++ +f+ahk+ La++S++F+ +f+ +++e++ ++++++k++ ++ f+++l+F+Y g++++
   Q: 32   DVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERD-QDKIHLKGLTATGFSHVLQFMYYGTIEL 96
           9***********************************9.************************9876 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MAGDVEGFSS SIHDTSVSAG FRALYEEGLL LDVTLVIEDH QFQAHKALLA TQSDYFRIMF 60
TADMRERDQD KIHLKGLTAT GFSHVLQFMY YGTIELSMNT VHEILQAAMY VQLIEVVKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGGTTTGAA TCCACTTCTG TGGCAGTGTT CTGAAGAGAC CTGAAGATCA CCTTACGCCT 60
CAGCTTACCA CAAACTGCAA ACAGCAAAAT GACAGTCAGG TAAAGCCAAA ACAGCCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030597--KLHL15
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005634--C:nucleus
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome

KEGG

mgp:100546998

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001418	Ailuropoda melanoleuca	94.70	0.00e+00	1121.00
IUUC-Apl-003970	Anas platyrhynchos	100.00	0.00e+00	1172.00
IUUC-Aca-005217	Anolis carolinensis	98.01	0.00e+00	1154.00
IUUC-Ame-011065	Astyanax mexicanus	87.09	0.00e+00	1083.00
IUUC-Bta-012443	Bos taurus	93.87	0.00e+00	1115.00
IUUC-Cja-019831	Callithrix jacchus	94.54	0.00e+00	1118.00
IUUC-Cfa-020941	Canis familiaris	94.87	0.00e+00	1123.00
IUUC-Cpo-021730	Cavia porcellus	94.37	0.00e+00	1120.00
IUUC-Csa-023247	Chlorocebus sabaeus	94.37	0.00e+00	1117.00
IUUC-Dre-028474	Danio rerio	87.09	0.00e+00	1087.00
IUUC-Dno-029411	Dasypus novemcinctus	95.20	0.00e+00	1123.00
IUUC-Dor-030576	Dipodomys ordii	94.21	0.00e+00	1117.00
IUUC-Dse-031404	Dothistroma septosporum	26.76	7.00e-03	31.60
IUUC-Ete-032327	Echinops telfairi	91.72	0.00e+00	1076.00
IUUC-Eca-033477	Equus caballus	94.37	0.00e+00	1118.00
IUUC-Fca-035546	Felis catus	94.70	0.00e+00	1123.00
IUUC-Fal-037370	Ficedula albicollis	100.00	0.00e+00	1172.00
IUUC-Gmo-038961	Gadus morhua	84.07	0.00e+00	1000.00
IUUC-Gga-041049	Gallus gallus	99.83	0.00e+00	1170.00
IUUC-Gac-042003	Gasterosteus aculeatus	83.25	0.00e+00	1003.00
IUUC-Ggo-044451	Gorilla gorilla	94.37	0.00e+00	1117.00
IUUC-Hsa-045874	Homo sapiens	94.37	0.00e+00	1117.00
IUUC-Itr-048357	Ictidomys tridecemlineatus	94.54	0.00e+00	1120.00
IUUC-Lch-049603	Latimeria chalumnae	91.10	1.00e-128	451.00
IUUC-Loc-052300	Lepisosteus oculatus	91.39	0.00e+00	1124.00
IUUC-Laf-054459	Loxodonta africana	95.20	0.00e+00	1123.00
IUUC-Mcc-054846	Macaca mulatta	94.37	0.00e+00	1117.00
IUUC-Meu-056797	Macropus eugenii	99.10	5.00e-116	410.00
IUUC-Mmr-061125	Microcebus murinus	93.54	0.00e+00	1110.00
IUUC-Mdo-062947	Monodelphis domestica	96.03	0.00e+00	1119.00
IUUC-Mmu-063708	Mus musculus	94.87	0.00e+00	1122.00
IUUC-Mpu-066447	Mustela putorius furo	94.83	0.00e+00	1114.00
IUUC-Mlu-066999	Myotis lucifugus	90.66	0.00e+00	945.00
IUUC-Nle-069918	Nomascus leucogenys	94.37	0.00e+00	1117.00
IUUC-Ont-071446	Oreochromis niloticus	84.32	0.00e+00	986.00
IUUC-Oan-072872	Ornithorhynchus anatinus	93.54	0.00e+00	1139.00
IUUC-Ocu-073969	Oryctolagus cuniculus	94.48	0.00e+00	879.00
IUUC-Ola-087557	Oryzias latipes	82.62	2.00e-151	527.00
IUUC-Oga-088567	Otolemur garnettii	94.54	0.00e+00	1117.00
IUUC-Oar-089882	Ovis aries	94.04	0.00e+00	1115.00
IUUC-Ptr-091229	Pan troglodytes	94.40	0.00e+00	1089.00
IUUC-Pan-091977	Papio anubis	94.37	0.00e+00	1117.00
IUUC-Psi-093496	Pelodiscus sinensis	98.98	9.00e-162	562.00
IUUC-Pfo-096759	Poecilia formosa	83.39	0.00e+00	1004.00
IUUC-Pab-098480	Pongo abelii	94.37	0.00e+00	1117.00
IUUC-Rno-105500	Rattus norvegicus	94.87	0.00e+00	1122.00
IUUC-Sha-106521	Sarcophilus harrisii	95.42	0.00e+00	1085.00
IUUC-Ssc-116372	Sus scrofa	94.37	0.00e+00	1120.00
IUUC-Tgu-116481	Taeniopygia guttata	100.00	0.00e+00	1172.00
IUUC-Tru-118542	Takifugu rubripes	81.77	0.00e+00	994.00
IUUC-Tsy-118848	Tarsius syrichta	93.64	2.00e-121	429.00
IUUC-Tni-119989	Tetraodon nigroviridis	82.23	0.00e+00	933.00
IUUC-Tbe-127485	Tupaia belangeri	94.70	0.00e+00	1120.00
IUUC-Ttr-129214	Tursiops truncatus	94.04	0.00e+00	1113.00
IUUC-Vpa-130261	Vicugna pacos	91.72	0.00e+00	1077.00
IUUC-Xtr-132092	Xenopus tropicalis	91.89	0.00e+00	1051.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence