iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049792

Ensembl Protein ID

ENSLACP00000023586.1

UniProt Accession

M3XLI0; M3XLI0_LATCH

Genbank Protein ID

ENSLACP00000023586

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01249941

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000022196.1	ENSLACT00000026133.1	ENSLACP00000023586.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.50e-48	164.3	1	110
UBD/UBC-like/UBD_UBC	1.30e-71	239.3	1	113

Active Site

Position(s)	Description	Evidence
56	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 27   ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaepnpe 115
           +++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++Wspal++++vllsi+sll++pnp+
   Q: 1    MFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQWSPALTISKVLLSICSLLCDPNPD 87
           789*********************************************************9..************************** PP
   S: 116  splneeaaellkknreeykkkvr 138
           +pl  e+a+++k++re+y++ +r
   Q: 88   DPLVPEIARIYKTDREKYNRLAR 110
           *******************9886 PP

UBD/UBC-like/UBD_UBC

   S: 26   lfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaaltlskvllslcslladaepddp 114
           +f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+alt+skvlls+csll+d++pddp
   Q: 1    MFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDP 89
           89*************************************************************************************** PP
   S: 115  lvaeiariyktdkekykriarewt 138
           lv+eiariyktd+eky+r ar+wt
   Q: 90   LVPEIARIYKTDREKYNRLARDWT 113
           ***********************8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MFHWQATIMG PNDSPYQGGV FFLTIHFPTD YPFKPPKVAF TTRIYHPNIN SNGSICLDIL 60
RSQWSPALTI SKVLLSICSL LCDPNPDDPL VPEIARIYKT DREKYNRLAR DWTSKYAM 118

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATCCTCCT CTAATTAAAA GTGAAATTGT CTGGCTGTGT GATCAGTTTG AACTGATAAG 60
TTGTTGGAAT CCTGTAGTAA ACTAAATATA GTTTTAAGGG TCTAATATTT AGTTGTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dor-030488	Dipodomys ordii	97.44	2.00e-66	245.00
IUUC-Eeu-035113	Erinaceus europaeus	97.44	4.00e-66	242.00
IUUC-Fca-036022	Felis catus	97.46	7.00e-67	244.00
IUUC-Fal-037217	Ficedula albicollis	97.44	4.00e-66	242.00
IUUC-Ome-081213	Oryza meridionalis	82.20	4.00e-57	212.00
IUUC-Oar-090331	Ovis aries	97.46	7.00e-67	244.00
IUUC-Rno-105628	Rattus norvegicus	96.61	2.00e-66	243.00
IUUC-Tgu-117070	Taeniopygia guttata	97.44	4.00e-66	242.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence