iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062973

UUCD1 version

UUC-MoD-00998

Ensembl Protein ID

ENSMODP00000013269.3

UniProt Accession

F7GHR6; F7GHR6_MONDO

Protein Name

Ribosome biogenesis protein BOP1; Block of proliferation 1 protein

Gene Name

BOP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010589.3	ENSMODT00000013511.3	ENSMODP00000013269.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-19	67.8	479	518

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+d v+cl+  ++ + l+sGsdD+++++WD+  g++lk+
   Q: 479  GHSDLVRCLSVsPNgHWLASGSDDHSVRLWDVYAGRCLKT 518
           8***********77799********************986 PP

Organism

Monodelphis domestica

Functional Description
(View)

Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

Protein Sequence
(Fasta)

MRILSSVPRK RVSFAQPRQL WRSRRYVSRR RILSLIRDWT GRVGKERRGL PAPLPGSGAR 60
NGGNMAGARG GRRAGMEAGA RARTGKRPAE QDPELQEAGS SEEPSPFTRP DLSQSAADSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTTCCGTA CCCAGAGACG AGTGCTTCGG CGCATGCGCA TATTGTCTTC TGTTCCTAGG 60
AAAAGGGTTT CCTTTGCGCA GCCGCGGCAG CTGTGGCGCT CCCGTCGCTA CGTCTCGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR028598--BOP1/Erb1
IPR012953--BOP1_N_dom
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08145--BOP1NT
PF00400--WD40

SMART

SM01035--BOP1NT
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0003723--F:RNA binding
GO:0008283--P:cell proliferation
GO:0000448--P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0051726--P:regulation of cell cycle

KEGG

mdo:100018165

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001158	Aegilops tauschii	41.32	3.00e-124	439.00
IUUC-Aml-001507	Ailuropoda melanoleuca	76.12	0.00e+00	983.00
IUUC-Atr-003141	Amborella trichopoda	41.40	6.00e-89	321.00
IUUC-Apl-003545	Anas platyrhynchos	68.47	0.00e+00	813.00
IUUC-Aly-005649	Arabidopsis lyrata	44.88	6.00e-158	551.00
IUUC-Ath-007625	Arabidopsis thaliana	44.04	3.00e-156	545.00
IUUC-Ago-007958	Ashbya gossypii	42.90	2.00e-163	569.00
IUUC-Acl-008344	Aspergillus clavatus	42.92	3.00e-143	502.00
IUUC-Afl-008616	Aspergillus flavus	42.66	3.00e-147	515.00
IUUC-Afu-009083	Aspergillus fumigatus	43.73	3.00e-141	496.00
IUUC-Ani-009365	Aspergillus nidulans	43.45	3.00e-147	516.00
IUUC-Ang-009796	Aspergillus niger	42.51	8.00e-140	491.00
IUUC-Aor-010015	Aspergillus oryzae	42.66	2.00e-147	516.00
IUUC-Ate-010537	Aspergillus terreus	42.57	1.00e-150	527.00
IUUC-Ame-011767	Astyanax mexicanus	70.68	2.00e-116	411.00
IUUC-Bgr-012286	Blumeria graminis	43.14	7.00e-153	534.00
IUUC-Bta-013569	Bos taurus	82.76	0.00e+00	1036.00
IUUC-Bci-013820	Botrytis cinerea	42.86	1.00e-145	510.00
IUUC-Bdi-014895	Brachypodium distachyon	46.23	1.00e-158	553.00
IUUC-Bol-016099	Brassica oleracea	44.57	4.00e-157	548.00
IUUC-Bra-017174	Brassica rapa	44.41	2.00e-157	550.00
IUUC-Cel-018201	Caenorhabditis elegans	47.36	6.00e-157	547.00
IUUC-Cja-019009	Callithrix jacchus	72.12	0.00e+00	901.00
IUUC-Cfa-020173	Canis familiaris	75.76	0.00e+00	976.00
IUUC-Cpo-021796	Cavia porcellus	83.58	0.00e+00	1038.00
IUUC-Cre-022650	Chlamydomonas reinhardtii	46.62	4.00e-154	538.00
IUUC-Csa-023440	Chlorocebus sabaeus	84.07	0.00e+00	1076.00
IUUC-Cin-025782	Ciona intestinalis	54.07	0.00e+00	736.00
IUUC-Csv-026352	Ciona savignyi	55.38	0.00e+00	741.00
IUUC-Cgl-026393	Colletotrichum gloeosporioides	38.27	4.00e-115	409.00
IUUC-Cne-027004	Cryptococcus neoformans	44.88	5.00e-170	591.00
IUUC-Cme-027242	Cyanidioschyzon merolae	40.06	5.00e-127	448.00
IUUC-Dre-028658	Danio rerio	74.04	0.00e+00	1005.00
IUUC-Dno-028883	Dasypus novemcinctus	82.28	0.00e+00	1033.00
IUUC-Dor-031031	Dipodomys ordii	79.20	0.00e+00	1070.00
IUUC-Dse-031443	Dothistroma septosporum	40.36	1.00e-145	509.00
IUUC-Dme-031786	Drosophila melanogaster	52.04	0.00e+00	742.00
IUUC-Eca-033677	Equus caballus	83.74	0.00e+00	1050.00
IUUC-Eeu-035310	Erinaceus europaeus	80.36	0.00e+00	855.00
IUUC-Fca-035888	Felis catus	80.36	0.00e+00	1024.00
IUUC-Fal-037438	Ficedula albicollis	66.55	0.00e+00	728.00
IUUC-Fox-037973	Fusarium oxysporum	41.36	8.00e-159	554.00
IUUC-Fso-038187	Fusarium solani	40.53	1.00e-157	550.00
IUUC-Gmo-039114	Gadus morhua	66.50	0.00e+00	848.00
IUUC-Ggr-039746	Gaeumannomyces graminis	41.42	6.00e-155	541.00
IUUC-Gga-040631	Gallus gallus	71.98	2.00e-152	531.00
IUUC-Gac-042582	Gasterosteus aculeatus	69.04	0.00e+00	889.00
IUUC-Gma-044215	Glycine max	43.68	7.00e-154	537.00
IUUC-Ggo-045587	Gorilla gorilla	84.28	0.00e+00	1077.00
IUUC-Hsa-046319	Homo sapiens	81.79	0.00e+00	1079.00
IUUC-Hvu-047526	Hordeum vulgare	45.34	6.00e-150	524.00
IUUC-Itr-048683	Ictidomys tridecemlineatus	82.76	0.00e+00	1046.00
IUUC-Kpa-049221	Komagataella pastoris	43.03	4.00e-157	548.00
IUUC-Lch-049640	Latimeria chalumnae	75.96	0.00e+00	1031.00
IUUC-Lpe-051135	Leersia perrieri	42.63	8.00e-137	480.00
IUUC-Loc-051930	Lepisosteus oculatus	74.68	0.00e+00	1000.00
IUUC-Lma-053290	Leptosphaeria maculans	42.79	3.00e-146	512.00
IUUC-Laf-053903	Loxodonta africana	77.11	0.00e+00	932.00
IUUC-Mcc-055471	Macaca mulatta	80.33	0.00e+00	1073.00
IUUC-Meu-056190	Macropus eugenii	94.16	0.00e+00	1159.00
IUUC-Mor-057135	Magnaporthe oryzae	41.64	1.00e-147	517.00
IUUC-Mpo-057475	Magnaporthe poae	40.96	1.00e-143	503.00
IUUC-Mtr-058689	Medicago truncatula	40.47	2.00e-131	463.00
IUUC-Mla-059149	Melampsora laricipopulina	45.30	8.00e-171	593.00
IUUC-Mga-059645	Meleagris gallopavo	62.30	4.00e-94	337.00
IUUC-Mvi-060485	Microbotryum violaceum	45.19	1.00e-150	528.00
IUUC-Mmr-061674	Microcebus murinus	83.31	0.00e+00	1047.00
IUUC-Mmu-064180	Mus musculus	77.94	0.00e+00	1049.00
IUUC-Mac-064535	Musa acuminata	38.34	2.00e-97	350.00
IUUC-Mpu-066406	Mustela putorius furo	80.95	0.00e+00	1060.00
IUUC-Mlu-067795	Myotis lucifugus	83.41	0.00e+00	1014.00
IUUC-Nfi-068516	Neosartorya fischeri	43.29	7.00e-135	474.00
IUUC-Ncr-068767	Neurospora crassa	41.67	4.00e-138	485.00
IUUC-Opr-071084	Ochotona princeps	78.21	3.00e-132	464.00
IUUC-Ont-071614	Oreochromis niloticus	70.11	0.00e+00	936.00
IUUC-Oba-075980	Oryza barthii	42.65	2.00e-135	476.00
IUUC-Obr-076799	Oryza brachyantha	45.10	6.00e-151	527.00
IUUC-Ogl-077134	Oryza glaberrima	44.62	1.00e-145	510.00
IUUC-Ogu-078655	Oryza glumaepatula	43.18	5.00e-140	491.00
IUUC-Oin-079654	Oryza indica	44.62	2.00e-145	509.00
IUUC-Olo-080706	Oryza longistaminata	42.65	1.00e-135	477.00
IUUC-Ome-081716	Oryza meridionalis	39.19	6.00e-115	408.00
IUUC-Oni-082508	Oryza nivara	42.88	1.00e-136	480.00
IUUC-Opu-083707	Oryza punctata	42.81	1.00e-135	477.00
IUUC-Oru-084453	Oryza rufipogon	42.65	1.00e-135	477.00
IUUC-Osa-085811	Oryza sativa	44.62	9.00e-146	510.00
IUUC-Ola-087361	Oryzias latipes	69.63	0.00e+00	947.00
IUUC-Oga-088015	Otolemur garnettii	83.09	0.00e+00	1077.00
IUUC-Oar-090058	Ovis aries	56.95	1.00e-109	390.00
IUUC-Ptr-090631	Pan troglodytes	76.80	9.00e-136	476.00
IUUC-Pan-092306	Papio anubis	80.51	0.00e+00	1072.00
IUUC-Pma-094622	Petromyzon marinus	71.47	0.00e+00	959.00
IUUC-Pno-094794	Phaeosphaeria nodorum	39.60	2.00e-134	473.00
IUUC-Ppa-095528	Physcomitrella patens	43.13	6.00e-96	345.00
IUUC-Pfo-096682	Poecilia formosa	69.78	0.00e+00	951.00
IUUC-Pab-097939	Pongo abelii	82.95	0.00e+00	958.00
IUUC-Pop-099530	Populus trichocarpa	44.83	2.00e-139	489.00
IUUC-Pca-100333	Procavia capensis	80.91	0.00e+00	1058.00
IUUC-Ppe-102078	Prunus persica	43.43	2.00e-148	520.00
IUUC-Pgr-103525	Puccinia graminis	47.27	3.00e-165	575.00
IUUC-Ptt-103929	Puccinia triticina	46.12	4.00e-160	558.00
IUUC-Pte-104029	Pyrenophora teres	42.95	4.00e-157	548.00
IUUC-Pyt-104446	Pyrenophora triticirepentis	43.10	2.00e-157	549.00
IUUC-Rno-105248	Rattus norvegicus	78.28	0.00e+00	1043.00
IUUC-Sce-106381	Saccharomyces cerevisiae	41.06	2.00e-157	549.00
IUUC-Sha-106519	Sarcophilus harrisii	92.94	0.00e+00	1181.00
IUUC-Sja-107908	Schizosaccharomyces japonicus	40.03	2.00e-140	492.00
IUUC-Spo-108071	Schizosaccharomyces pombe	40.72	1.00e-139	490.00
IUUC-Smo-109604	Selaginella moellendorffii	46.41	2.00e-157	549.00
IUUC-Sit-110551	Setaria italica	44.94	2.00e-148	519.00
IUUC-Sly-110970	Solanum lycopersicum	44.83	2.00e-78	286.00
IUUC-Stu-112593	Solanum tuberosum	44.86	2.00e-153	536.00
IUUC-Sar-113123	Sorex araneus	76.19	8.00e-132	462.00
IUUC-Sbi-113945	Sorghum bicolor	43.82	2.00e-150	526.00
IUUC-Sre-115188	Sporisorium reilianum	45.67	1.00e-164	573.00
IUUC-Ssc-115352	Sus scrofa	82.82	0.00e+00	1030.00
IUUC-Tru-117685	Takifugu rubripes	70.13	0.00e+00	944.00
IUUC-Tni-119982	Tetraodon nigroviridis	70.97	0.00e+00	903.00
IUUC-Tca-121664	Theobroma cacao	45.05	7.00e-160	557.00
IUUC-Tre-122229	Trichoderma reesei	42.75	3.00e-138	485.00
IUUC-Tvi-122576	Trichoderma virens	42.53	2.00e-142	499.00
IUUC-Tae-124110	Triticum aestivum	45.09	8.00e-141	494.00
IUUC-Tur-126781	Triticum urartu	41.89	9.00e-121	427.00
IUUC-Tme-127080	Tuber melanosporum	45.55	5.00e-174	604.00
IUUC-Ttr-128514	Tursiops truncatus	78.39	0.00e+00	712.00
IUUC-Uma-129556	Ustilago maydis	44.12	3.00e-157	548.00
IUUC-Vda-129715	Verticillium dahliae	41.91	1.00e-151	530.00
IUUC-Vvi-131211	Vitis vinifera	43.49	9.00e-147	513.00
IUUC-Xma-133883	Xiphophorus maculatus	69.95	0.00e+00	916.00
IUUC-Yli-134438	Yarrowia lipolytica	42.92	5.00e-144	504.00
IUUC-Zma-135341	Zea mays	41.07	2.00e-89	323.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence