iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116967

Ensembl Protein ID

ENSTGUP00000008714.1

UniProt Accession

H0ZDQ2; H0ZDQ2_TAEGU

Genbank Protein ID

ENSTGUP00000008714

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01027938

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008457.1	ENSTGUT00000008807.1	ENSTGUP00000008714.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	72.24	3.00e-146	515.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

GDAPRRVPVS QHSAQSRSLT SGAPARVLCP ANFAQRVPVQ PQKPVLSTQK QPSDQPAQQL 60
RPKVPQQAAV RPQAASKGSE KPPQAAAPAQ NPEAESTSKQ KTEETKKKRM QWSLDDFEIG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGATGCCC CCAGACGCGT CCCCGTGTCG CAGCACTCAG CCCAGAGCCG CTCACTGACC 60
AGTGGAGCTC CAGCCCGAGT TCTGTGTCCT GCAAACTTCG CCCAGCGAGT CCCCGTGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	68.44	1.00e-106	378.00
IUUC-Aml-001426	Ailuropoda melanoleuca	73.60	1.00e-154	539.00
IUUC-Atr-002453	Amborella trichopoda	68.44	2.00e-107	381.00
IUUC-Apl-003626	Anas platyrhynchos	84.08	5.00e-173	599.00
IUUC-Aca-004602	Anolis carolinensis	69.92	3.00e-154	537.00
IUUC-Aly-005878	Arabidopsis lyrata	65.78	4.00e-104	370.00
IUUC-Ath-007117	Arabidopsis thaliana	65.78	1.00e-103	369.00
IUUC-Acl-008199	Aspergillus clavatus	58.91	4.00e-85	308.00
IUUC-Afl-008419	Aspergillus flavus	58.53	1.00e-84	306.00
IUUC-Afu-008751	Aspergillus fumigatus	58.91	1.00e-84	306.00
IUUC-Ani-009181	Aspergillus nidulans	51.78	2.00e-89	321.00
IUUC-Ang-009787	Aspergillus niger	59.30	1.00e-85	309.00
IUUC-Aor-009980	Aspergillus oryzae	58.53	1.00e-84	306.00
IUUC-Ate-010286	Aspergillus terreus	58.91	7.00e-85	306.00
IUUC-Ame-010849	Astyanax mexicanus	72.04	3.00e-131	461.00
IUUC-Bgr-012110	Blumeria graminis	60.92	8.00e-88	317.00
IUUC-Bta-013474	Bos taurus	75.93	3.00e-157	547.00
IUUC-Bci-013756	Botrytis cinerea	61.39	2.00e-93	335.00
IUUC-Bdi-014257	Brachypodium distachyon	68.44	9.00e-107	379.00
IUUC-Bol-016310	Brassica oleracea	66.92	1.00e-104	372.00
IUUC-Bra-017438	Brassica rapa	66.54	2.00e-104	371.00
IUUC-Cel-018157	Caenorhabditis elegans	62.65	5.00e-99	353.00
IUUC-Cja-019282	Callithrix jacchus	77.84	2.00e-154	538.00
IUUC-Cfa-020162	Canis familiaris	75.00	9.00e-156	542.00
IUUC-Cpo-021764	Cavia porcellus	71.20	1.00e-148	518.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	68.30	2.00e-109	388.00
IUUC-Csa-023694	Chlorocebus sabaeus	73.91	5.00e-150	523.00
IUUC-Cho-024350	Choloepus hoffmanni	88.78	1.00e-101	361.00
IUUC-Cin-025542	Ciona intestinalis	74.62	4.00e-121	426.00
IUUC-Csv-025873	Ciona savignyi	68.01	3.00e-122	430.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	56.15	3.00e-80	291.00
IUUC-Cne-026928	Cryptococcus neoformans	63.04	2.00e-97	348.00
IUUC-Cme-027336	Cyanidioschyzon merolae	63.53	5.00e-120	424.00
IUUC-Dre-028198	Danio rerio	63.64	8.00e-134	469.00
IUUC-Dno-029928	Dasypus novemcinctus	71.24	7.00e-149	519.00
IUUC-Dor-030238	Dipodomys ordii	68.10	4.00e-136	477.00
IUUC-Dse-031266	Dothistroma septosporum	53.73	1.00e-92	333.00
IUUC-Dme-032007	Drosophila melanogaster	62.21	6.00e-102	363.00
IUUC-Ete-032911	Echinops telfairi	56.08	2.00e-100	358.00
IUUC-Eca-033749	Equus caballus	74.73	4.00e-155	540.00
IUUC-Eeu-035170	Erinaceus europaeus	73.88	5.00e-152	530.00
IUUC-Fca-035498	Felis catus	74.87	7.00e-157	546.00
IUUC-Fal-037397	Ficedula albicollis	90.10	0.00e+00	635.00
IUUC-Fox-037747	Fusarium oxysporum	60.54	6.00e-90	323.00
IUUC-Fso-038429	Fusarium solani	59.77	2.00e-87	315.00
IUUC-Gmo-039378	Gadus morhua	61.93	4.00e-134	470.00
IUUC-Ggr-039939	Gaeumannomyces graminis	61.69	8.00e-93	333.00
IUUC-Gga-040187	Gallus gallus	83.02	3.00e-173	600.00
IUUC-Gac-042223	Gasterosteus aculeatus	63.38	1.00e-137	482.00
IUUC-Gma-042870	Glycine max	66.54	2.00e-98	351.00
IUUC-Ggo-045617	Gorilla gorilla	74.93	2.00e-154	538.00
IUUC-Hsa-046968	Homo sapiens	74.93	2.00e-154	538.00
IUUC-Hvu-047072	Hordeum vulgare	55.34	2.00e-80	291.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	63.47	1.00e-122	432.00
IUUC-Kpa-049093	Komagataella pastoris	56.70	7.00e-79	286.00
IUUC-Lch-050346	Latimeria chalumnae	67.12	2.00e-144	504.00
IUUC-Lpe-051466	Leersia perrieri	69.20	8.00e-108	382.00
IUUC-Lma-053006	Leptosphaeria maculans	52.05	1.00e-90	326.00
IUUC-Laf-053422	Loxodonta africana	71.93	3.00e-150	524.00
IUUC-Mcc-055245	Macaca mulatta	77.27	7.00e-150	523.00
IUUC-Mor-056952	Magnaporthe oryzae	59.39	3.00e-90	324.00
IUUC-Mpo-057605	Magnaporthe poae	61.30	7.00e-93	333.00
IUUC-Mtr-057726	Medicago truncatula	66.54	4.00e-105	374.00
IUUC-Mla-059174	Melampsora laricipopulina	65.25	4.00e-101	361.00
IUUC-Mga-059562	Meleagris gallopavo	65.59	9.00e-129	452.00
IUUC-Mvi-060305	Microbotryum violaceum	63.57	8.00e-94	337.00
IUUC-Mmr-061588	Microcebus murinus	73.99	6.00e-153	533.00
IUUC-Mdo-061914	Monodelphis domestica	71.73	4.00e-153	533.00
IUUC-Mmu-063288	Mus musculus	73.58	2.00e-149	521.00
IUUC-Mac-064969	Musa acuminata	67.30	8.00e-106	375.00
IUUC-Mpu-066855	Mustela putorius furo	74.27	5.00e-155	540.00
IUUC-Mlu-068046	Myotis lucifugus	73.66	2.00e-152	531.00
IUUC-Nfi-068527	Neosartorya fischeri	58.91	4.00e-85	307.00
IUUC-Ncr-068678	Neurospora crassa	60.31	3.00e-91	328.00
IUUC-Nle-069848	Nomascus leucogenys	74.66	2.00e-153	535.00
IUUC-Opr-070589	Ochotona princeps	71.93	7.00e-151	526.00
IUUC-Ont-071733	Oreochromis niloticus	63.32	4.00e-126	444.00
IUUC-Oan-073399	Ornithorhynchus anatinus	83.56	6.00e-147	512.00
IUUC-Ocu-074063	Oryctolagus cuniculus	74.41	9.00e-156	542.00
IUUC-Oba-075264	Oryza barthii	68.82	9.00e-107	379.00
IUUC-Obr-076048	Oryza brachyantha	68.44	1.00e-106	378.00
IUUC-Ogl-077637	Oryza glaberrima	68.82	1.00e-106	378.00
IUUC-Ogu-078830	Oryza glumaepatula	68.82	5.00e-107	379.00
IUUC-Oin-079150	Oryza indica	68.82	5.00e-107	380.00
IUUC-Olo-080398	Oryza longistaminata	53.93	7.00e-83	299.00
IUUC-Ome-081544	Oryza meridionalis	56.27	1.00e-89	322.00
IUUC-Oni-082250	Oryza nivara	68.82	5.00e-107	380.00
IUUC-Opu-083638	Oryza punctata	68.82	1.00e-106	379.00
IUUC-Oru-084981	Oryza rufipogon	68.82	4.00e-107	380.00
IUUC-Osa-085961	Oryza sativa	68.82	4.00e-107	380.00
IUUC-Olu-087880	Ostreococcus lucimarinus	70.11	7.00e-111	393.00
IUUC-Oga-088891	Otolemur garnettii	74.32	1.00e-153	535.00
IUUC-Oar-090021	Ovis aries	75.00	7.00e-154	536.00
IUUC-Ptr-091458	Pan troglodytes	75.20	1.00e-154	538.00
IUUC-Pan-092546	Papio anubis	77.56	1.00e-150	525.00
IUUC-Psi-093280	Pelodiscus sinensis	78.32	4.00e-164	570.00
IUUC-Pma-094298	Petromyzon marinus	79.09	2.00e-122	431.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.62	2.00e-87	315.00
IUUC-Ppa-095855	Physcomitrella patens	67.68	3.00e-109	387.00
IUUC-Pfo-096428	Poecilia formosa	64.62	9.00e-131	459.00
IUUC-Pab-098696	Pongo abelii	73.94	5.00e-151	526.00
IUUC-Pop-099405	Populus trichocarpa	66.04	1.00e-105	375.00
IUUC-Pca-100740	Procavia capensis	70.63	7.00e-151	526.00
IUUC-Ppe-101854	Prunus persica	66.54	1.00e-105	375.00
IUUC-Pva-103212	Pteropus vampyrus	74.40	7.00e-153	532.00
IUUC-Pgr-103474	Puccinia graminis	64.39	5.00e-101	360.00
IUUC-Ptt-103933	Puccinia triticina	50.19	1.00e-63	236.00
IUUC-Pte-104089	Pyrenophora teres	51.70	4.00e-90	324.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	60.31	7.00e-90	323.00
IUUC-Rno-105057	Rattus norvegicus	74.40	1.00e-151	528.00
IUUC-Sha-107137	Sarcophilus harrisii	75.74	1.00e-155	542.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	62.40	2.00e-98	352.00
IUUC-Spo-108078	Schizosaccharomyces pombe	64.82	2.00e-100	358.00
IUUC-Smo-109288	Selaginella moellendorffii	68.06	2.00e-109	388.00
IUUC-Sit-110246	Setaria italica	68.44	1.00e-106	378.00
IUUC-Sly-111379	Solanum lycopersicum	66.42	2.00e-105	374.00
IUUC-Stu-112777	Solanum tuberosum	62.28	1.00e-105	375.00
IUUC-Sbi-114325	Sorghum bicolor	68.06	2.00e-106	377.00
IUUC-Sre-115203	Sporisorium reilianum	60.23	6.00e-81	294.00
IUUC-Ssc-115361	Sus scrofa	75.93	2.00e-159	554.00
IUUC-Tru-117570	Takifugu rubripes	63.76	1.00e-136	479.00
IUUC-Tsy-119280	Tarsius syrichta	87.37	4.00e-103	367.00
IUUC-Tni-120721	Tetraodon nigroviridis	66.67	2.00e-136	478.00
IUUC-Tca-121494	Theobroma cacao	65.66	1.00e-104	372.00
IUUC-Tre-121869	Trichoderma reesei	53.69	5.00e-93	334.00
IUUC-Tvi-122510	Trichoderma virens	61.83	2.00e-91	328.00
IUUC-Tae-123071	Triticum aestivum	68.44	1.00e-106	378.00
IUUC-Tur-126240	Triticum urartu	68.44	2.00e-106	377.00
IUUC-Tme-126921	Tuber melanosporum	57.54	2.00e-94	338.00
IUUC-Tbe-127872	Tupaia belangeri	68.17	5.00e-137	480.00
IUUC-Ttr-129134	Tursiops truncatus	75.86	1.00e-152	532.00
IUUC-Uma-129412	Ustilago maydis	60.46	1.00e-78	286.00
IUUC-Vda-130003	Verticillium dahliae	59.92	7.00e-91	327.00
IUUC-Vvi-131272	Vitis vinifera	61.15	8.00e-106	375.00
IUUC-Xtr-132019	Xenopus tropicalis	66.75	4.00e-145	507.00
IUUC-Xma-134203	Xiphophorus maculatus	64.23	6.00e-136	476.00
IUUC-Yli-134503	Yarrowia lipolytica	56.59	2.00e-89	321.00
IUUC-Zma-135232	Zea mays	67.68	2.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence