iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045620

UUCD1 version

UUC-GoG-00630

Ensembl Protein ID

ENSGGOP00000015901.2

UniProt Accession

G3RJK8; G3RJK8_GORGO

Protein Name

Uncharacterized protein

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000016304.2	ENSGGOT00000016355.2	ENSGGOP00000015901.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	100.00	1.00e-111	399.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

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Nucleotide Sequence
(Fasta)

CTCGAGGGAC GCGCGCGCGA AGGCTCCTTT GTGGACTTCA CGGCCGCCAA CATCTGGGCG 60
CAGCGCGGGC CACCGCTGGC CGTCTCGCCG CCGCGTCGCC TTGGGGACCC GAGGGGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

KEGG

ggo:101123839

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	96.44	9.00e-108	382.00
IUUC-Apl-003607	Anas platyrhynchos	82.22	8.00e-97	345.00
IUUC-Aca-005063	Anolis carolinensis	82.38	2.00e-103	367.00
IUUC-Ath-006990	Arabidopsis thaliana	32.94	8.00e-03	36.20
IUUC-Ame-010859	Astyanax mexicanus	57.39	4.00e-71	260.00
IUUC-Bta-012817	Bos taurus	91.70	2.00e-111	394.00
IUUC-Bra-017963	Brassica rapa	30.00	5.40e-02	32.30
IUUC-Cja-019605	Callithrix jacchus	99.11	2.00e-114	404.00
IUUC-Cfa-021231	Canis familiaris	97.78	3.00e-109	387.00
IUUC-Cpo-022003	Cavia porcellus	91.23	1.00e-107	381.00
IUUC-Csa-023511	Chlorocebus sabaeus	100.00	6.00e-113	399.00
IUUC-Dre-028536	Danio rerio	59.57	8.00e-74	269.00
IUUC-Dno-029003	Dasypus novemcinctus	92.44	4.00e-110	390.00
IUUC-Eca-034205	Equus caballus	83.80	3.00e-68	250.00
IUUC-Fca-036317	Felis catus	95.96	2.00e-108	384.00
IUUC-Gmo-038777	Gadus morhua	63.89	8.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	83.11	6.00e-97	346.00
IUUC-Gac-041837	Gasterosteus aculeatus	55.90	2.00e-65	241.00
IUUC-Hsa-046909	Homo sapiens	100.00	6.00e-113	399.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	91.91	6.00e-112	396.00
IUUC-Lch-049510	Latimeria chalumnae	68.12	7.00e-85	306.00
IUUC-Loc-052863	Lepisosteus oculatus	63.04	1.00e-79	288.00
IUUC-Laf-054136	Loxodonta africana	92.54	2.00e-109	387.00
IUUC-Mcc-055383	Macaca mulatta	100.00	6.00e-113	399.00
IUUC-Meu-056153	Macropus eugenii	88.50	2.00e-110	391.00
IUUC-Mmr-061185	Microcebus murinus	95.13	3.00e-107	380.00
IUUC-Mdo-061819	Monodelphis domestica	89.33	1.00e-113	402.00
IUUC-Mmu-064231	Mus musculus	96.89	2.00e-119	421.00
IUUC-Mpu-066691	Mustela putorius furo	98.67	3.00e-109	387.00
IUUC-Mlu-067673	Myotis lucifugus	96.02	3.00e-116	410.00
IUUC-Ont-072406	Oreochromis niloticus	55.02	2.00e-68	251.00
IUUC-Oan-073249	Ornithorhynchus anatinus	74.67	6.00e-94	336.00
IUUC-Ocu-074935	Oryctolagus cuniculus	88.41	5.00e-32	128.00
IUUC-Ola-087373	Oryzias latipes	48.04	3.00e-48	184.00
IUUC-Oga-088041	Otolemur garnettii	92.89	1.00e-109	388.00
IUUC-Oar-089646	Ovis aries	90.39	2.00e-103	368.00
IUUC-Ptr-091502	Pan troglodytes	100.00	6.00e-113	399.00
IUUC-Pan-091934	Papio anubis	100.00	6.00e-113	399.00
IUUC-Pfo-096412	Poecilia formosa	42.79	3.00e-48	184.00
IUUC-Pab-098554	Pongo abelii	100.00	6.00e-113	399.00
IUUC-Rno-105874	Rattus norvegicus	96.44	4.00e-119	420.00
IUUC-Sha-107151	Sarcophilus harrisii	87.28	3.00e-110	390.00
IUUC-Ssc-115722	Sus scrofa	88.37	2.00e-65	240.00
IUUC-Tgu-117151	Taeniopygia guttata	84.00	4.00e-97	347.00
IUUC-Tru-118428	Takifugu rubripes	54.15	2.00e-68	251.00
IUUC-Tni-120590	Tetraodon nigroviridis	54.59	3.00e-67	247.00
IUUC-Ttr-129065	Tursiops truncatus	93.01	4.00e-111	393.00
IUUC-Xtr-132167	Xenopus tropicalis	65.78	9.00e-82	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence