iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033220

UUCD1 version

UUC-EqC-01014

Ensembl Protein ID

ENSECAP00000021698.1

UniProt Accession

F6WKP5; F6WKP5_HORSE

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024190.1	ENSECAT00000026045.1	ENSECAP00000021698.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.50e-72	245.0	3	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakq 93
           +++wl+Le++P++ +++++++g++ ++q+ ++y++dpe l+++++pv+++lllF+i+ek+e +r+++   ++++++++d++++++f+kq
   Q: 3    GQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEE--EEKIKSQGQDVTSSVYFMKQ 89
           589*************************************************************766..5589**************** PP
   S: 94   vigNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfv 181
           +i+N+C+t++l+++++n++dk+ ++ G+tl++++e++ ++spe++a+ l+n ++++++h++ a+++++++p+ +       +k  +hf+
   Q: 90   TISNACGTIGLIHAIANNKDKMhFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSPD-------EKVDLHFI 171
           ***********************************************************************877.......7899**** PP
   S: 182  syvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           ++v+++g+lyeldg+kpfP+++g++++++ l+d+++v+++f+er    + de+rfn++a++a+
   Q: 172  ALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMER----DPDELRFNAIALSAA 230
           ********************************************....***********9875 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MEGQRWLPLE ANPEVTNQFL KQLGLHPNWQ FVDVYGMDPE LLSMVPRPVC AVLLLFPITE 60
KYEVFRTEEE EKIKSQGQDV TSSVYFMKQT ISNACGTIGL IHAIANNKDK MHFESGSTLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGCTGGAG AGGGGCCGGG CGGAGCGGCC ATGGAGGGTC AGCGCTGGCT CCCGTTGGAG 60
GCCAATCCCG AGGTGAGCGC AGCTCGGATC TCGGTCTGAG GACTCGGGCA GGGACGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ecb:100050355; ecb:100052000

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	44.07	4.00e-53	201.00
IUUC-Aml-001344	Ailuropoda melanoleuca	99.57	2.00e-136	477.00
IUUC-Atr-002931	Amborella trichopoda	47.49	9.00e-48	182.00
IUUC-Apl-003949	Anas platyrhynchos	86.85	6.00e-104	369.00
IUUC-Aca-004924	Anolis carolinensis	82.25	3.00e-114	404.00
IUUC-Aly-005721	Arabidopsis lyrata	50.22	3.00e-60	224.00
IUUC-Ath-006827	Arabidopsis thaliana	50.88	2.00e-60	225.00
IUUC-Ago-007950	Ashbya gossypii	35.59	1.00e-28	119.00
IUUC-Acl-008305	Aspergillus clavatus	39.56	3.00e-40	158.00
IUUC-Afl-008611	Aspergillus flavus	40.25	2.00e-43	168.00
IUUC-Afu-008945	Aspergillus fumigatus	40.68	3.00e-43	167.00
IUUC-Ani-009339	Aspergillus nidulans	40.51	6.00e-44	170.00
IUUC-Ang-009691	Aspergillus niger	38.72	4.00e-43	167.00
IUUC-Aor-009961	Aspergillus oryzae	40.25	1.00e-43	169.00
IUUC-Ate-010316	Aspergillus terreus	40.85	2.00e-44	171.00
IUUC-Ame-011157	Astyanax mexicanus	73.04	6.00e-101	359.00
IUUC-Bgr-012125	Blumeria graminis	36.71	8.00e-40	156.00
IUUC-Bta-012673	Bos taurus	98.70	2.00e-135	474.00
IUUC-Bci-013734	Botrytis cinerea	37.61	2.00e-42	165.00
IUUC-Bdi-014330	Brachypodium distachyon	45.81	5.00e-56	211.00
IUUC-Bol-015214	Brassica oleracea	52.86	1.00e-63	235.00
IUUC-Bra-017491	Brassica rapa	53.30	4.00e-63	234.00
IUUC-Cel-018302	Caenorhabditis elegans	40.09	8.00e-36	143.00
IUUC-Cfa-020371	Canis familiaris	96.84	2.00e-106	377.00
IUUC-Cpo-022036	Cavia porcellus	96.09	2.00e-130	457.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	44.19	4.00e-38	150.00
IUUC-Csa-023854	Chlorocebus sabaeus	98.70	1.00e-134	471.00
IUUC-Cho-024548	Choloepus hoffmanni	56.38	7.00e-20	90.10
IUUC-Cin-025545	Ciona intestinalis	49.78	6.00e-67	246.00
IUUC-Cgl-026409	Colletotrichum gloeosporioides	34.47	3.00e-32	131.00
IUUC-Cne-026914	Cryptococcus neoformans	35.19	2.00e-30	125.00
IUUC-Cme-027216	Cyanidioschyzon merolae	37.84	4.00e-28	117.00
IUUC-Dre-028356	Danio rerio	74.35	1.00e-102	365.00
IUUC-Dse-031461	Dothistroma septosporum	40.51	5.00e-39	154.00
IUUC-Dme-032146	Drosophila melanogaster	50.67	3.00e-62	231.00
IUUC-Fca-036421	Felis catus	99.57	2.00e-136	477.00
IUUC-Fal-036773	Ficedula albicollis	86.64	1.00e-105	375.00
IUUC-Fox-037830	Fusarium oxysporum	36.80	3.00e-41	161.00
IUUC-Fso-038259	Fusarium solani	36.68	3.00e-39	157.00
IUUC-Gmo-039468	Gadus morhua	68.26	2.00e-83	301.00
IUUC-Ggr-039832	Gaeumannomyces graminis	37.12	2.00e-37	149.00
IUUC-Gga-041205	Gallus gallus	85.22	6.00e-111	392.00
IUUC-Gac-041629	Gasterosteus aculeatus	68.42	3.00e-87	314.00
IUUC-Gma-043057	Glycine max	49.78	8.00e-54	203.00
IUUC-Ggo-044533	Gorilla gorilla	99.13	5.00e-135	473.00
IUUC-Hsa-046754	Homo sapiens	99.57	2.00e-136	477.00
IUUC-Hvu-047176	Hordeum vulgare	40.61	3.00e-43	167.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	97.47	8.00e-91	325.00
IUUC-Kpa-049123	Komagataella pastoris	37.09	6.00e-33	133.00
IUUC-Lch-049685	Latimeria chalumnae	78.07	5.00e-109	386.00
IUUC-Lpe-051377	Leersia perrieri	45.32	3.00e-47	181.00
IUUC-Loc-051988	Lepisosteus oculatus	76.09	5.00e-105	373.00
IUUC-Lma-053316	Leptosphaeria maculans	40.26	1.00e-42	166.00
IUUC-Laf-053985	Loxodonta africana	97.84	1.00e-133	468.00
IUUC-Mcc-055888	Macaca mulatta	97.39	2.00e-131	461.00
IUUC-Mor-057271	Magnaporthe oryzae	37.12	3.00e-41	161.00
IUUC-Mpo-057343	Magnaporthe poae	32.19	3.00e-22	97.80
IUUC-Mtr-057713	Medicago truncatula	48.67	9.00e-54	202.00
IUUC-Mla-058942	Melampsora laricipopulina	45.37	1.00e-47	182.00
IUUC-Mga-059702	Meleagris gallopavo	86.38	2.00e-103	367.00
IUUC-Mvi-060249	Microbotryum violaceum	44.30	2.00e-41	162.00
IUUC-Mmr-061284	Microcebus murinus	100.00	3.00e-92	331.00
IUUC-Mdo-062639	Monodelphis domestica	79.48	6.00e-122	429.00
IUUC-Mmu-063299	Mus musculus	97.83	1.00e-134	471.00
IUUC-Mac-065075	Musa acuminata	45.85	5.00e-54	203.00
IUUC-Mpu-066769	Mustela putorius furo	99.57	2.00e-136	477.00
IUUC-Mlu-066937	Myotis lucifugus	96.52	1.00e-131	461.00
IUUC-Nfi-068320	Neosartorya fischeri	41.10	3.00e-44	171.00
IUUC-Ncr-068673	Neurospora crassa	38.96	2.00e-45	175.00
IUUC-Nle-069175	Nomascus leucogenys	99.53	2.00e-123	434.00
IUUC-Opr-070652	Ochotona princeps	100.00	4.00e-64	237.00
IUUC-Ont-072170	Oreochromis niloticus	70.61	1.00e-88	318.00
IUUC-Oan-073247	Ornithorhynchus anatinus	93.81	2.00e-59	219.00
IUUC-Ocu-074422	Oryctolagus cuniculus	97.83	6.00e-135	472.00
IUUC-Oba-075098	Oryza barthii	42.04	3.00e-50	191.00
IUUC-Obr-076041	Oryza brachyantha	45.18	6.00e-55	206.00
IUUC-Ogl-076980	Oryza glaberrima	45.61	1.00e-54	206.00
IUUC-Ogu-078978	Oryza glumaepatula	38.74	7.00e-48	183.00
IUUC-Oin-079285	Oryza indica	41.59	2.00e-49	188.00
IUUC-Olo-080671	Oryza longistaminata	42.04	1.00e-49	189.00
IUUC-Ome-081428	Oryza meridionalis	41.15	2.00e-48	184.00
IUUC-Oni-082406	Oryza nivara	42.04	3.00e-50	191.00
IUUC-Opu-083305	Oryza punctata	42.04	9.00e-49	186.00
IUUC-Oru-084969	Oryza rufipogon	42.04	3.00e-50	191.00
IUUC-Osa-085830	Oryza sativa	45.61	1.00e-54	206.00
IUUC-Ola-086893	Oryzias latipes	68.42	5.00e-85	306.00
IUUC-Olu-087858	Ostreococcus lucimarinus	44.93	8.00e-53	199.00
IUUC-Oga-088055	Otolemur garnettii	99.13	5.00e-135	473.00
IUUC-Oar-090319	Ovis aries	98.26	5.00e-135	473.00
IUUC-Pan-092714	Papio anubis	98.27	7.00e-134	469.00
IUUC-Psi-094036	Pelodiscus sinensis	86.18	2.00e-105	374.00
IUUC-Pma-094412	Petromyzon marinus	64.94	3.00e-55	206.00
IUUC-Pno-094997	Phaeosphaeria nodorum	36.22	7.00e-35	140.00
IUUC-Ppa-095519	Physcomitrella patens	50.67	2.00e-63	234.00
IUUC-Pfo-096182	Poecilia formosa	67.83	1.00e-87	315.00
IUUC-Pab-098216	Pongo abelii	99.31	2.00e-82	296.00
IUUC-Pop-099282	Populus trichocarpa	49.12	8.00e-54	202.00
IUUC-Pca-100818	Procavia capensis	43.88	1.00e-34	139.00
IUUC-Ppe-101332	Prunus persica	48.23	5.00e-56	210.00
IUUC-Pgr-103430	Puccinia graminis	47.48	5.00e-51	194.00
IUUC-Ptt-103955	Puccinia triticina	49.14	1.00e-51	195.00
IUUC-Pte-104414	Pyrenophora teres	38.89	1.00e-39	155.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	34.03	3.00e-34	138.00
IUUC-Rno-105096	Rattus norvegicus	96.96	1.00e-133	468.00
IUUC-Sce-106412	Saccharomyces cerevisiae	36.08	3.00e-28	118.00
IUUC-Sha-106677	Sarcophilus harrisii	93.55	9.00e-121	425.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	30.95	2.00e-26	111.00
IUUC-Spo-108322	Schizosaccharomyces pombe	31.00	3.00e-26	111.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	37.61	8.00e-39	153.00
IUUC-Smo-108914	Selaginella moellendorffii	48.71	4.00e-54	204.00
IUUC-Sit-110163	Setaria italica	46.98	1.00e-55	209.00
IUUC-Sly-111613	Solanum lycopersicum	49.78	2.00e-62	231.00
IUUC-Stu-112526	Solanum tuberosum	50.88	7.00e-58	216.00
IUUC-Sbi-114545	Sorghum bicolor	46.29	2.00e-53	201.00
IUUC-Sre-114961	Sporisorium reilianum	42.49	2.00e-40	159.00
IUUC-Ssc-115255	Sus scrofa	97.17	6.00e-122	429.00
IUUC-Tgu-117003	Taeniopygia guttata	85.65	3.00e-110	390.00
IUUC-Tru-118330	Takifugu rubripes	62.30	8.00e-68	251.00
IUUC-Tsy-119488	Tarsius syrichta	98.25	2.00e-63	234.00
IUUC-Tni-120042	Tetraodon nigroviridis	64.13	4.00e-70	259.00
IUUC-Tca-120976	Theobroma cacao	47.79	4.00e-56	210.00
IUUC-Tre-122149	Trichoderma reesei	38.70	2.00e-43	168.00
IUUC-Tvi-122450	Trichoderma virens	38.70	2.00e-43	168.00
IUUC-Tae-122693	Triticum aestivum	45.22	1.00e-53	202.00
IUUC-Tur-126250	Triticum urartu	44.07	1.00e-52	199.00
IUUC-Tme-126961	Tuber melanosporum	37.02	4.00e-36	144.00
IUUC-Uma-129382	Ustilago maydis	41.38	3.00e-43	167.00
IUUC-Vda-129678	Verticillium dahliae	32.07	7.00e-32	130.00
IUUC-Vpa-130783	Vicugna pacos	99.13	1.00e-63	235.00
IUUC-Vvi-131661	Vitis vinifera	48.03	2.00e-57	214.00
IUUC-Xtr-132428	Xenopus tropicalis	74.35	3.00e-106	377.00
IUUC-Xma-134245	Xiphophorus maculatus	67.11	2.00e-87	315.00
IUUC-Yli-134570	Yarrowia lipolytica	35.90	1.00e-36	145.00
IUUC-Zma-134740	Zea mays	45.41	4.00e-55	207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence