iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000011333.2	ENSSTOT00000028798.1	ENSSTOP00000017912.1
ENSSTOG00000011333.2	ENSSTOT00000011355.2	ENSSTOP00000010190.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-77	261.4	42	482

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  +++a s+ el++++++++ e  +
   Q: 42   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGFLEDKDKPDakvrIIPLQLQRLFAQLLLLDQEAASTVELTNSFGWTSDE--E 128
           9*****************************888888766543333244558899******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +q++c+ec+n+s+++e+fldl+++
   Q: 129  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTIVNQVVCNECKNISEKQEDFLDLTVA 191
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++ +n y+c +c+++++a k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 192  VKNVS-----GLEDALwNMYVEEEVFDYDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSSYTFPLRINLKP 275
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e ++  +++Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 276  FCEQSELDDL-EYIYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfkqeerkpdvnlktlqneeeiddplvilqavilqeennlisvd 363
           ****999987.9***************************************************************************** PP
   S: 302  .................................................................................ekgkWllf 309
                                                                                               +W+ +
   Q: 364  qlgqkllkkmgiswnkkyrkyhgplrkflqlhsqmfllssdgstvsllkkdpvqsksdfqstdqqsfhslaleapglsdstACSHWFDI 452
           ********************************************************99999999999999998888876544444**** PP
   S: 310  dDskVtevkeeevleetg..staYvlfYkr 337
           +DskV++++e++++++ +  ++aY+lfY++
   Q: 453  NDSKVQPIQEKDIEQQFQgkESAYMLFYRK 482
           ***************9889*********98 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MFGDLFEEDY SSVSNNQYGK GKKLKNKALE PPAPREFTNL SGIRNQGGTC YLNSLLQTLH 60
FTPEFREALF SLGPEELGFL EDKDKPDAKV RIIPLQLQRL FAQLLLLDQE AASTVELTNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGGG ACCTATTTGA AGAGGATTAT TCCAGTGTGT CAAATAATCA GTATGGAAAA 60
GGGAAGAAAT TAAAGAATAA AGCTTTGGAG CCACCTGCTC CCAGAGAATT CACCAATTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	80.73	0.00e+00	1868.00
IUUC-Apl-004105	Anas platyrhynchos	62.38	0.00e+00	1495.00
IUUC-Aca-004715	Anolis carolinensis	60.27	0.00e+00	1426.00
IUUC-Ame-011073	Astyanax mexicanus	47.15	0.00e+00	997.00
IUUC-Bta-012487	Bos taurus	78.77	0.00e+00	1904.00
IUUC-Cja-018937	Callithrix jacchus	82.11	0.00e+00	2000.00
IUUC-Cfa-020645	Canis familiaris	74.42	0.00e+00	1182.00
IUUC-Cpo-022160	Cavia porcellus	80.00	0.00e+00	1956.00
IUUC-Csa-023078	Chlorocebus sabaeus	80.97	0.00e+00	2013.00
IUUC-Cho-025013	Choloepus hoffmanni	63.17	0.00e+00	783.00
IUUC-Csv-026193	Ciona savignyi	55.60	4.00e-58	217.00
IUUC-Dre-027416	Danio rerio	47.47	0.00e+00	1104.00
IUUC-Dno-029639	Dasypus novemcinctus	76.67	0.00e+00	1590.00
IUUC-Dor-030624	Dipodomys ordii	89.04	2.00e-152	533.00
IUUC-Ete-032626	Echinops telfairi	63.74	0.00e+00	746.00
IUUC-Eca-034208	Equus caballus	81.05	0.00e+00	1984.00
IUUC-Eeu-035340	Erinaceus europaeus	58.02	6.00e-45	176.00
IUUC-Fca-035886	Felis catus	72.73	0.00e+00	759.00
IUUC-Fal-036925	Ficedula albicollis	62.93	0.00e+00	1422.00
IUUC-Gmo-038597	Gadus morhua	45.57	0.00e+00	897.00
IUUC-Gga-041171	Gallus gallus	62.62	0.00e+00	1482.00
IUUC-Gac-041362	Gasterosteus aculeatus	45.24	0.00e+00	941.00
IUUC-Ggo-045069	Gorilla gorilla	80.51	0.00e+00	1820.00
IUUC-Hsa-046715	Homo sapiens	82.34	0.00e+00	2015.00
IUUC-Lch-050182	Latimeria chalumnae	51.26	0.00e+00	1101.00
IUUC-Loc-052705	Lepisosteus oculatus	52.31	0.00e+00	1223.00
IUUC-Laf-054132	Loxodonta africana	79.11	0.00e+00	1940.00
IUUC-Mcc-055734	Macaca mulatta	81.45	0.00e+00	2010.00
IUUC-Meu-056135	Macropus eugenii	84.55	6.00e-113	401.00
IUUC-Mga-060092	Meleagris gallopavo	61.96	0.00e+00	1452.00
IUUC-Mmr-061546	Microcebus murinus	78.50	0.00e+00	1900.00
IUUC-Mdo-061935	Monodelphis domestica	60.40	0.00e+00	1444.00
IUUC-Mmu-063630	Mus musculus	79.66	0.00e+00	1964.00
IUUC-Mpu-066579	Mustela putorius furo	77.08	0.00e+00	1927.00
IUUC-Mlu-068034	Myotis lucifugus	79.92	0.00e+00	1893.00
IUUC-Nle-069082	Nomascus leucogenys	79.83	0.00e+00	1653.00
IUUC-Opr-070953	Ochotona princeps	68.31	0.00e+00	923.00
IUUC-Ont-072435	Oreochromis niloticus	46.07	0.00e+00	1073.00
IUUC-Oan-073339	Ornithorhynchus anatinus	65.24	0.00e+00	1525.00
IUUC-Ocu-073760	Oryctolagus cuniculus	79.02	0.00e+00	1943.00
IUUC-Ola-087015	Oryzias latipes	45.12	0.00e+00	890.00
IUUC-Oga-088960	Otolemur garnettii	81.45	0.00e+00	1998.00
IUUC-Oar-089853	Ovis aries	79.47	0.00e+00	1931.00
IUUC-Ptr-091093	Pan troglodytes	82.34	0.00e+00	2015.00
IUUC-Pan-091962	Papio anubis	80.58	0.00e+00	1996.00
IUUC-Psi-093691	Pelodiscus sinensis	64.00	0.00e+00	1550.00
IUUC-Pma-094428	Petromyzon marinus	64.39	2.00e-91	328.00
IUUC-Pfo-096983	Poecilia formosa	46.82	0.00e+00	991.00
IUUC-Pab-097860	Pongo abelii	81.13	0.00e+00	1854.00
IUUC-Pca-100514	Procavia capensis	74.11	5.00e-173	601.00
IUUC-Pva-102771	Pteropus vampyrus	79.02	0.00e+00	1793.00
IUUC-Rno-105405	Rattus norvegicus	78.69	0.00e+00	1909.00
IUUC-Sha-107376	Sarcophilus harrisii	61.88	0.00e+00	1404.00
IUUC-Ssc-115819	Sus scrofa	74.91	0.00e+00	1324.00
IUUC-Tgu-117262	Taeniopygia guttata	61.50	0.00e+00	1469.00
IUUC-Tru-117601	Takifugu rubripes	47.47	0.00e+00	1070.00
IUUC-Tsy-118996	Tarsius syrichta	70.73	0.00e+00	1540.00
IUUC-Tni-120682	Tetraodon nigroviridis	42.17	0.00e+00	837.00
IUUC-Tbe-127616	Tupaia belangeri	61.83	0.00e+00	1204.00
IUUC-Ttr-129075	Tursiops truncatus	77.47	0.00e+00	1790.00
IUUC-Vpa-130108	Vicugna pacos	79.53	0.00e+00	1726.00
IUUC-Xtr-132623	Xenopus tropicalis	51.67	0.00e+00	1171.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence