iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033898

UUCD1 version

UUC-EqC-00429

Ensembl Protein ID

ENSECAP00000019318.1

UniProt Accession

F6X4R2; F6X4R2_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021887.1	ENSECAT00000023333.1	ENSECAP00000019318.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-08	34.2	11	54
E3 activity/RING/U-box	2.70e-06	27.5	6	72

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p++l+C H f++ C+ ++w+ +   ++++  CP Cr
   Q: 11   CSICLSIYQD-PVSLGCEHYFCRRCItEHWVRQE--AQGARDCPECR 54
           **********.*******************5555..**********8 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwl....asggktcPvtrqplteedlvPnltlrrli 65
            +e+lC+I l + +dPv l + + + r++I ++     a+g + cP +r++++e  l P+l l ++ 
   Q: 6    KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWvrqeAQGARDCPECRRTFAEPALAPSLKLANIT 72
           689***************************9888455444444****************99987766 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MACSLKDELL CSICLSIYQD PVSLGCEHYF CRRCITEHWV RQEAQGARDC PECRRTFAEP 60
ALAPSLKLAN ITVSYSSYLR DAVSDAQRHS VACSVTQLPE CLCPAGSSLC CFFSQERAAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGTA GCCTCAAGGA CGAGCTGCTC TGCTCCATCT GCCTGAGCAT CTACCAGGAC 60
CCGGTGAGCC TGGGCTGCGA GCACTACTTC TGCCGCCGCT GCATCACGGA GCACTGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0032897--P:negative regulation of viral transcription
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002199	Ailuropoda melanoleuca	76.35	0.00e+00	801.00
IUUC-Apl-003767	Anas platyrhynchos	71.17	0.00e+00	689.00
IUUC-Aca-004412	Anolis carolinensis	85.40	0.00e+00	639.00
IUUC-Ame-010927	Astyanax mexicanus	67.60	0.00e+00	736.00
IUUC-Bta-012927	Bos taurus	76.16	0.00e+00	800.00
IUUC-Cja-019317	Callithrix jacchus	70.58	0.00e+00	712.00
IUUC-Cfa-020292	Canis familiaris	96.56	0.00e+00	690.00
IUUC-Cpo-022274	Cavia porcellus	96.85	0.00e+00	696.00
IUUC-Csa-023042	Chlorocebus sabaeus	76.35	0.00e+00	801.00
IUUC-Dre-028493	Danio rerio	67.23	0.00e+00	736.00
IUUC-Dno-030029	Dasypus novemcinctus	72.25	0.00e+00	742.00
IUUC-Dor-031051	Dipodomys ordii	77.56	0.00e+00	778.00
IUUC-Ete-032752	Echinops telfairi	98.90	2.00e-109	389.00
IUUC-Eeu-034659	Erinaceus europaeus	93.98	2.00e-82	298.00
IUUC-Fca-035492	Felis catus	79.26	0.00e+00	831.00
IUUC-Fal-036867	Ficedula albicollis	61.30	2.00e-179	621.00
IUUC-Gmo-038916	Gadus morhua	67.23	0.00e+00	709.00
IUUC-Gga-040360	Gallus gallus	89.85	0.00e+00	627.00
IUUC-Gac-041871	Gasterosteus aculeatus	67.60	0.00e+00	738.00
IUUC-Ggo-044411	Gorilla gorilla	73.47	0.00e+00	739.00
IUUC-Hsa-047025	Homo sapiens	79.33	0.00e+00	845.00
IUUC-Itr-047905	Ictidomys tridecemlineatus	76.35	0.00e+00	801.00
IUUC-Loc-052114	Lepisosteus oculatus	68.90	0.00e+00	752.00
IUUC-Laf-054359	Loxodonta africana	92.90	0.00e+00	636.00
IUUC-Mcc-055563	Macaca mulatta	76.35	0.00e+00	801.00
IUUC-Meu-056027	Macropus eugenii	58.47	1.00e-168	585.00
IUUC-Mga-060146	Meleagris gallopavo	68.64	8.00e-44	169.00
IUUC-Mmr-060822	Microcebus murinus	76.35	0.00e+00	800.00
IUUC-Mdo-062117	Monodelphis domestica	59.88	2.00e-145	508.00
IUUC-Mmu-064086	Mus musculus	76.16	0.00e+00	800.00
IUUC-Mpu-066378	Mustela putorius furo	76.35	0.00e+00	801.00
IUUC-Mlu-067155	Myotis lucifugus	78.76	0.00e+00	832.00
IUUC-Nle-069464	Nomascus leucogenys	76.16	0.00e+00	800.00
IUUC-Opr-071058	Ochotona princeps	99.10	6.00e-134	470.00
IUUC-Ont-071253	Oreochromis niloticus	62.01	0.00e+00	633.00
IUUC-Oan-073614	Ornithorhynchus anatinus	94.30	6.00e-92	328.00
IUUC-Ola-086794	Oryzias latipes	67.41	0.00e+00	732.00
IUUC-Oga-088889	Otolemur garnettii	75.98	0.00e+00	799.00
IUUC-Oar-089203	Ovis aries	77.82	0.00e+00	741.00
IUUC-Ptr-090795	Pan troglodytes	79.14	0.00e+00	845.00
IUUC-Pfo-096942	Poecilia formosa	67.23	0.00e+00	726.00
IUUC-Pab-097936	Pongo abelii	95.69	6.00e-137	479.00
IUUC-Pca-100397	Procavia capensis	75.05	0.00e+00	790.00
IUUC-Ppe-101916	Prunus persica	32.95	2.00e-09	58.50
IUUC-Pva-102293	Pteropus vampyrus	96.85	0.00e+00	684.00
IUUC-Rno-105551	Rattus norvegicus	76.16	0.00e+00	799.00
IUUC-Sre-115193	Sporisorium reilianum	45.83	3.00e-07	50.40
IUUC-Ssc-115983	Sus scrofa	76.35	0.00e+00	801.00
IUUC-Tgu-117279	Taeniopygia guttata	70.24	2.00e-129	455.00
IUUC-Tru-118238	Takifugu rubripes	67.41	0.00e+00	732.00
IUUC-Tni-119788	Tetraodon nigroviridis	49.62	2.00e-131	462.00
IUUC-Uma-129518	Ustilago maydis	45.83	4.00e-07	50.40
IUUC-Xtr-132768	Xenopus tropicalis	71.15	6.00e-142	497.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence