iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062117

UUCD1 version

UUC-MoD-00299

Ensembl Protein ID

ENSMODP00000021332.3

UniProt Accession

F6V365; F6V365_MONDO

Protein Name

Uncharacterized protein

Gene Name

TRIM62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000017094.3	ENSMODT00000021706.3	ENSMODP00000021332.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.40e-07	29.7	6	75
E3 activity/RING/RING	1.70e-08	35.0	11	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwl....asggktcPvtrqplteedlvPnltlrrliqaw 68
            +e+lC+I l + +dPv l + + + r++I ++     a+g + cP +r++++e  l P+l l ++++++
   Q: 6    KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWvrqeAQGARDCPECRRTFAEPALAPSLKLANIVERY 75
           689***************************9888455444444*******************99999887 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p++l+C H f++ C+ ++w+ +   ++++  CP Cr
   Q: 11   CSICLSIYQD-PVSLGCEHYFCRRCItEHWVRQE--AQGARDCPECR 54
           **********.*******************5555..**********8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MACSLKDELL CSICLSIYQD PVSLGCEHYF CRRCITEHWV RQEAQGARDC PECRRTFAEP 60
ALAPSLKLAN IVERYSAFPL DAILSARRAA LPCQAHEKVK LFCLTDRALV CFFCDEPALH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACAGAAGA AGCCAGCGTC TGGCTGGCCA GGACTTGAAG CAGCTGCCTC TGGTCGTCCC 60
TCCCCCGTCG GGGCGGAGCT CGGCTCTCCA GGCTCCGCCC GGGACGGACC AGCCGGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0032897--P:negative regulation of viral transcription
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002199	Ailuropoda melanoleuca	78.71	0.00e+00	644.00
IUUC-Apl-003767	Anas platyrhynchos	72.28	2.00e-157	548.00
IUUC-Aca-004412	Anolis carolinensis	68.72	5.00e-158	550.00
IUUC-Ame-010927	Astyanax mexicanus	71.53	2.00e-178	618.00
IUUC-Bta-012927	Bos taurus	78.71	0.00e+00	644.00
IUUC-Cja-019317	Callithrix jacchus	77.10	2.00e-168	584.00
IUUC-Cfa-020292	Canis familiaris	69.96	9.00e-109	386.00
IUUC-Cpo-022274	Cavia porcellus	69.72	2.00e-110	392.00
IUUC-Csa-023042	Chlorocebus sabaeus	78.71	0.00e+00	644.00
IUUC-Dre-028493	Danio rerio	69.38	8.00e-174	603.00
IUUC-Dno-030029	Dasypus novemcinctus	73.68	7.00e-169	586.00
IUUC-Dor-031051	Dipodomys ordii	76.79	0.00e+00	652.00
IUUC-Ete-032752	Echinops telfairi	94.05	2.00e-83	302.00
IUUC-Eca-033898	Equus caballus	59.01	7.00e-154	537.00
IUUC-Fca-035492	Felis catus	69.76	3.00e-165	574.00
IUUC-Fal-036867	Ficedula albicollis	74.41	7.00e-175	606.00
IUUC-Gmo-038916	Gadus morhua	71.05	4.00e-171	593.00
IUUC-Gga-040360	Gallus gallus	75.12	7.00e-177	613.00
IUUC-Gac-041871	Gasterosteus aculeatus	71.53	3.00e-179	621.00
IUUC-Ggo-044411	Gorilla gorilla	70.95	3.00e-162	564.00
IUUC-Hsa-047025	Homo sapiens	77.99	0.00e+00	667.00
IUUC-Itr-047905	Ictidomys tridecemlineatus	78.71	0.00e+00	644.00
IUUC-Lch-050624	Latimeria chalumnae	79.14	4.00e-68	249.00
IUUC-Loc-052114	Lepisosteus oculatus	71.29	8.00e-179	619.00
IUUC-Laf-054359	Loxodonta africana	69.81	3.00e-112	398.00
IUUC-Mcc-055563	Macaca mulatta	78.71	0.00e+00	644.00
IUUC-Meu-056027	Macropus eugenii	97.62	2.00e-95	343.00
IUUC-Mga-060146	Meleagris gallopavo	85.88	7.00e-77	279.00
IUUC-Mmr-060822	Microcebus murinus	78.95	0.00e+00	645.00
IUUC-Mmu-064086	Mus musculus	78.47	0.00e+00	643.00
IUUC-Mpu-066378	Mustela putorius furo	78.71	0.00e+00	644.00
IUUC-Mlu-067155	Myotis lucifugus	77.51	0.00e+00	662.00
IUUC-Nle-069464	Nomascus leucogenys	78.47	0.00e+00	642.00
IUUC-Opr-071058	Ochotona princeps	92.59	4.00e-90	325.00
IUUC-Ont-071253	Oreochromis niloticus	61.76	3.00e-144	505.00
IUUC-Oan-073198	Ornithorhynchus anatinus	96.43	6.00e-86	309.00
IUUC-Ola-086794	Oryzias latipes	71.50	4.00e-178	617.00
IUUC-Oga-088889	Otolemur garnettii	78.47	0.00e+00	642.00
IUUC-Oar-089203	Ovis aries	71.62	1.00e-150	526.00
IUUC-Ptr-090795	Pan troglodytes	78.23	0.00e+00	669.00
IUUC-Pfo-096942	Poecilia formosa	66.74	1.00e-177	615.00
IUUC-Pab-097936	Pongo abelii	65.01	6.00e-131	460.00
IUUC-Pca-100397	Procavia capensis	78.23	0.00e+00	642.00
IUUC-Ppe-101916	Prunus persica	35.71	1.00e-09	58.90
IUUC-Pva-102293	Pteropus vampyrus	69.15	3.00e-106	378.00
IUUC-Rno-105551	Rattus norvegicus	78.23	0.00e+00	639.00
IUUC-Sre-115193	Sporisorium reilianum	45.83	3.00e-07	50.80
IUUC-Ssc-115983	Sus scrofa	78.71	0.00e+00	644.00
IUUC-Tgu-117279	Taeniopygia guttata	72.54	3.00e-152	531.00
IUUC-Tru-118238	Takifugu rubripes	71.53	2.00e-178	619.00
IUUC-Tni-119788	Tetraodon nigroviridis	90.60	5.00e-62	231.00
IUUC-Uma-129518	Ustilago maydis	45.83	3.00e-07	50.80
IUUC-Vvi-131261	Vitis vinifera	34.15	4.00e-07	50.80
IUUC-Xtr-132768	Xenopus tropicalis	61.07	3.00e-140	491.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence