iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049662

Ensembl Protein ID

ENSLACP00000013539.1

UniProt Accession

H3AV68; H3AV68_LATCH

Genbank Protein ID

ENSLACP00000013539

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01131911

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000011920.1	ENSLACT00000013635.1	ENSLACP00000013539.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-29	99.8	186	223
UBD/Beta-Prp	9.50e-51	172.9	343	547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W++  g+ll
   Q: 186  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTYNGRLL 223
           8**********955599**************9888876 PP

UBD/Beta-Prp

   S: 66   ilvtgseDrtikvwdls..tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...............tlsghd 137
           +l+tgs+D++i+ + l   t++ +  l+ h+d+v s++fs +gd++vsGs+d t+r+w  +++++ +                 ++  +
   Q: 343  FLATGSTDHLIRMYYLGtgTPEKIAELESHTDKVDSIQFSHTGDRFVSGSRDGTARIWLFQQQEWRSIlldmaaklpgepcseEEKFMK 431
           78899999999999555337778888889999999999999999999999999999998888888777888999999998776555666 PP
   S: 138  gvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght. 222
             v+++++++ ++ ++++ ++  +++W++ tg+ll+ ltg h+d v  l+   fds  + ++s+++dg++ +wd+ +g+ +r + +   
   Q: 432  PKVTMIAWDQCDSSVITAVNNHLLKVWNSYTGQLLHILTG-HEDEVFVLEphpFDS--RIMLSAGHDGSLFIWDITKGSKLRHYFNMIe 517
           6788999999889999999999999999999999999998.999999999766666..8899999999999999998888777665443 PP
   S: 223  ....dnvksvrfspnderlvsgssDgsiri 248
                 v + +fsp++++++++ s+g + +
   Q: 518  gqghGAVFDCKFSPDGQHFACTDSHGHLVV 547
           444456666788888888888877776655 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MAEKTAANRS ISPMESELYF LIARFLSAGP CQKSAEVLLR ELEEYQLLPK RLDWQGGEHN 60
RTYEELVLAN KHVAPDHLLQ ICQRIGPMLD KEIPPSVPEV QSLLGTGKQS LLRIAKDYRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGA AAACGGCTGC AAATCGCTCC ATATCGCCTA TGGAGTCAGG TAAGAAAGTT 60
AAAATACAAA AAAAAAAAAA AAAAATTAGG TTATAAAGTC AATAAAAAAA ATCTTATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.57	2.00e-63	238.00
IUUC-Aml-002332	Ailuropoda melanoleuca	66.34	0.00e+00	2057.00
IUUC-Atr-002600	Amborella trichopoda	29.69	4.00e-72	267.00
IUUC-Ath-006801	Arabidopsis thaliana	29.82	5.00e-67	250.00
IUUC-Ame-010718	Astyanax mexicanus	71.65	0.00e+00	1194.00
IUUC-Bta-013217	Bos taurus	65.94	0.00e+00	2139.00
IUUC-Bol-015737	Brassica oleracea	29.43	1.00e-69	258.00
IUUC-Bra-017961	Brassica rapa	29.91	5.00e-69	256.00
IUUC-Cja-019966	Callithrix jacchus	66.55	0.00e+00	2122.00
IUUC-Cfa-021037	Canis familiaris	78.54	0.00e+00	1283.00
IUUC-Cpo-021934	Cavia porcellus	69.87	0.00e+00	2070.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	35.06	4.00e-32	133.00
IUUC-Csa-023352	Chlorocebus sabaeus	66.02	0.00e+00	1924.00
IUUC-Cho-024690	Choloepus hoffmanni	83.05	0.00e+00	671.00
IUUC-Cin-025702	Ciona intestinalis	46.32	3.00e-81	294.00
IUUC-Csv-025813	Ciona savignyi	43.24	0.00e+00	638.00
IUUC-Dre-028205	Danio rerio	70.23	0.00e+00	1199.00
IUUC-Dno-028938	Dasypus novemcinctus	64.27	0.00e+00	2069.00
IUUC-Dor-030444	Dipodomys ordii	70.71	0.00e+00	674.00
IUUC-Dme-031752	Drosophila melanogaster	51.37	0.00e+00	697.00
IUUC-Eca-034349	Equus caballus	65.45	0.00e+00	2039.00
IUUC-Fca-035485	Felis catus	79.97	0.00e+00	1227.00
IUUC-Gga-040865	Gallus gallus	63.49	0.00e+00	2105.00
IUUC-Gma-043340	Glycine max	31.22	9.00e-73	269.00
IUUC-Ggo-045500	Gorilla gorilla	66.63	0.00e+00	2108.00
IUUC-Hsa-046350	Homo sapiens	66.65	0.00e+00	2132.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	66.72	0.00e+00	788.00
IUUC-Laf-053848	Loxodonta africana	68.61	0.00e+00	2027.00
IUUC-Mcc-054638	Macaca mulatta	66.71	0.00e+00	2125.00
IUUC-Meu-056739	Macropus eugenii	69.16	0.00e+00	984.00
IUUC-Mtr-058094	Medicago truncatula	31.11	4.00e-74	273.00
IUUC-Mmr-061227	Microcebus murinus	66.41	0.00e+00	2134.00
IUUC-Mdo-062074	Monodelphis domestica	76.74	0.00e+00	1280.00
IUUC-Mmu-064075	Mus musculus	65.04	0.00e+00	2116.00
IUUC-Mac-065343	Musa acuminata	30.97	7.00e-77	283.00
IUUC-Mpu-066643	Mustela putorius furo	65.78	0.00e+00	1989.00
IUUC-Mlu-067735	Myotis lucifugus	64.87	0.00e+00	2046.00
IUUC-Nle-069402	Nomascus leucogenys	66.63	0.00e+00	2119.00
IUUC-Ont-072298	Oreochromis niloticus	63.07	0.00e+00	1852.00
IUUC-Oan-072954	Ornithorhynchus anatinus	78.79	0.00e+00	1332.00
IUUC-Ocu-074456	Oryctolagus cuniculus	65.94	0.00e+00	2090.00
IUUC-Oba-075709	Oryza barthii	28.98	1.00e-60	229.00
IUUC-Obr-076619	Oryza brachyantha	30.44	3.00e-70	261.00
IUUC-Opu-083233	Oryza punctata	29.59	7.00e-64	239.00
IUUC-Oru-085195	Oryza rufipogon	28.98	9.00e-61	229.00
IUUC-Ola-086580	Oryzias latipes	56.33	0.00e+00	1630.00
IUUC-Olu-087745	Ostreococcus lucimarinus	30.00	4.00e-57	217.00
IUUC-Oga-087938	Otolemur garnettii	59.07	0.00e+00	1843.00
IUUC-Oar-090214	Ovis aries	65.43	0.00e+00	2023.00
IUUC-Ptr-091213	Pan troglodytes	66.65	0.00e+00	2126.00
IUUC-Pan-092444	Papio anubis	70.26	0.00e+00	2078.00
IUUC-Psi-093271	Pelodiscus sinensis	62.93	0.00e+00	1874.00
IUUC-Ppa-095793	Physcomitrella patens	28.92	5.00e-72	267.00
IUUC-Pab-097573	Pongo abelii	69.36	0.00e+00	2016.00
IUUC-Pva-102782	Pteropus vampyrus	69.85	0.00e+00	1999.00
IUUC-Rno-105687	Rattus norvegicus	64.71	0.00e+00	2078.00
IUUC-Sha-106680	Sarcophilus harrisii	77.30	0.00e+00	1290.00
IUUC-Sly-111348	Solanum lycopersicum	30.46	2.00e-72	268.00
IUUC-Sar-113519	Sorex araneus	67.11	0.00e+00	1151.00
IUUC-Tsy-118921	Tarsius syrichta	68.54	0.00e+00	1563.00
IUUC-Tca-121615	Theobroma cacao	29.93	1.00e-68	255.00
IUUC-Tae-125478	Triticum aestivum	30.35	2.00e-71	265.00
IUUC-Tur-126809	Triticum urartu	30.15	4.00e-69	257.00
IUUC-Ttr-128561	Tursiops truncatus	67.20	0.00e+00	1945.00
IUUC-Vpa-130444	Vicugna pacos	63.35	0.00e+00	1855.00
IUUC-Vvi-131362	Vitis vinifera	30.47	6.00e-75	276.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence