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Tag Content
UUCD2 ID IUUC-Dre-028260
UUCD1 version UUC-DaR-00968
Ensembl Protein ID ENSDARP00000054234.5
UniProt Accession Q5U3B5; Q5U3B5_DANRE
Genbank Protein ID AAH85620.1; AAI55784.1
Protein Name Pleiotropic regulator 1; Plrg1 protein
Genbank Nucleotide ID AL935184; BC155783
Gene Name plrg1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000037283.8 ENSDART00000054235.6 ENSDARP00000054234.5
ENSDARG00000037283.8 ENSDART00000131111.1 ENSDARP00000108468.1
ENSDARG00000037283.8 ENSDART00000123032.2 ENSDARP00000107485.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.70e-43 145.0 199 235
UBD/Beta-Prp 1.30e-60 206.0 202 489
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+++a  ++   +v+Gs D tik+WDl +g+l
   Q: 199  GHLGWVRSIAVePGnQWFVTGSADRTIKIWDLASGKL 235
           8***********77799***************99987 PP
   

   UBD/Beta-Prp
   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls 99
           + ++++++ p++++++tgs+d+tik+wd+ +gkl  sl gh ++v+ v  s+++++l +++eD+ +k wdl+ +k +++++gh + v++
   Q: 202  GWVRSIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVAVSNRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYD 290
           567789*********************************************************************************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
           l+++p+ d+lv+ s+d t+rvwd++t+  ++ tlsgh+ +v +v+ ++ +  +v+Gs D+t+rlWdl  gk   tlt  h++sv+ l +
   Q: 291  LDLHPTIDVLVTCSRDATARVWDIRTKANVH-TLSGHTNTVATVKCQSAEPQVVTGSHDTTIRLWDLVAGKTRATLTN-HKKSVRALVL 377
           *******************************.********************************************97.********** PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn.......ssvisv 270
           ++ +  ++sgs d+ +k w +  g+ ++ l gh++ ++ +++   d  lvsg++ g+i +Wd r+g + + +           +s i +
   Q: 378  HPRQYTFASGSPDN-IKQWKFPDGNFIQNLSGHNAIINTLAVN-SDGVLVSGADNGTIHMWDWRTGYNFQRIHAAVqpgsldsESGIFS 464
           ************96.***************************9.999*******************98888877668999*97666666 PP
   S: 271  avlsfgdnvlvlgsedskvniwklk 295
           +v++ +++ l+++++d++++++k +
   Q: 465  CVFDQSESRLITAEADKTIKVYKED 489
           6689******************975 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MTEDVQKHSV HTLVFRSLKR THDMFVADHA KPIAQDEQSF KVKMAAKMRA EYKAVLHMPV 60
LKEGREKGSL HTSDPYGQSA YPLPDTTPEY LVTGTHPYPS APGVALTADT QMLKMPSEMG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028260|E3,WD_repeat;UBD,Beta-Prp|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTAACACCCT ACCGGAAAAC GCTTTGTCGC GCCCGGAAGC TGTGCGTACG TTTGCACTAC 60
TGGTTCGGGT TGTGATTGTT CGGTGTGTTG GGAAGTTTCT TTATTTGCGT TAGTTCGTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028260|E3,WD_repeat;UBD,Beta-Prp|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0000398--P:mRNA splicing, via spliceosome
GO:0043066--P:negative regulation of apoptotic process
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000084 Aegilops tauschii 48.44 1.00e-131 463.00
IUUC-Aml-001605 Ailuropoda melanoleuca 78.99 0.00e+00 846.00
IUUC-Atr-002757 Amborella trichopoda 49.90 7.00e-131 461.00
IUUC-Apl-003198 Anas platyrhynchos 81.59 0.00e+00 884.00
IUUC-Aca-004683 Anolis carolinensis 81.24 0.00e+00 884.00
IUUC-Aly-005775 Arabidopsis lyrata 62.87 6.00e-129 454.00
IUUC-Ath-007460 Arabidopsis thaliana 62.57 3.00e-128 451.00
IUUC-Ago-007884 Ashbya gossypii 48.46 8.00e-105 374.00
IUUC-Acl-008153 Aspergillus clavatus 65.10 3.00e-133 468.00
IUUC-Afl-008384 Aspergillus flavus 61.26 7.00e-135 473.00
IUUC-Afu-009045 Aspergillus fumigatus 66.28 1.00e-134 473.00
IUUC-Ani-009229 Aspergillus nidulans 65.59 4.00e-133 468.00
IUUC-Ang-009812 Aspergillus niger 67.82 8.00e-128 449.00
IUUC-Aor-010059 Aspergillus oryzae 61.26 7.00e-135 473.00
IUUC-Ate-010351 Aspergillus terreus 65.69 1.00e-139 489.00
IUUC-Ame-011613 Astyanax mexicanus 65.70 1.00e-172 599.00
IUUC-Bgr-012042 Blumeria graminis 66.77 1.00e-139 489.00
IUUC-Bta-012406 Bos taurus 78.68 0.00e+00 840.00
IUUC-Bci-013760 Botrytis cinerea 61.01 1.00e-137 483.00
IUUC-Bdi-014776 Brachypodium distachyon 50.83 2.00e-132 465.00
IUUC-Bol-016189 Brassica oleracea 49.18 9.00e-129 453.00
IUUC-Bra-018044 Brassica rapa 49.39 4.00e-130 458.00
IUUC-Cel-018651 Caenorhabditis elegans 54.42 5.00e-158 550.00
IUUC-Cja-019974 Callithrix jacchus 78.68 0.00e+00 843.00
IUUC-Cfa-021085 Canis familiaris 78.88 0.00e+00 847.00
IUUC-Cpo-021458 Cavia porcellus 78.29 0.00e+00 844.00
IUUC-Cre-022880 Chlamydomonas reinhardtii 61.61 5.00e-125 440.00
IUUC-Csa-023883 Chlorocebus sabaeus 77.91 0.00e+00 834.00
IUUC-Cho-024623 Choloepus hoffmanni 78.04 0.00e+00 817.00
IUUC-Cin-025190 Ciona intestinalis 62.77 0.00e+00 662.00
IUUC-Csv-026367 Ciona savignyi 61.04 0.00e+00 657.00
IUUC-Cgl-026499 Colletotrichum gloeosporioides 68.40 4.00e-143 501.00
IUUC-Cne-027069 Cryptococcus neoformans 50.10 8.00e-131 460.00
IUUC-Cme-027233 Cyanidioschyzon merolae 29.57 1.00e-34 140.00
IUUC-Dno-029112 Dasypus novemcinctus 79.07 0.00e+00 844.00
IUUC-Dor-031118 Dipodomys ordii 82.24 0.00e+00 714.00
IUUC-Dse-031493 Dothistroma septosporum 57.18 2.00e-129 456.00
IUUC-Dme-032138 Drosophila melanogaster 57.97 3.00e-170 591.00
IUUC-Ete-032411 Echinops telfairi 70.14 0.00e+00 692.00
IUUC-Eca-033521 Equus caballus 79.46 0.00e+00 856.00
IUUC-Eeu-035249 Erinaceus europaeus 72.26 3.00e-171 595.00
IUUC-Fca-036358 Felis catus 78.49 0.00e+00 842.00
IUUC-Fal-036933 Ficedula albicollis 81.59 0.00e+00 880.00
IUUC-Fox-037713 Fusarium oxysporum 67.79 2.00e-142 499.00
IUUC-Fso-038380 Fusarium solani 67.58 4.00e-142 498.00
IUUC-Gmo-039133 Gadus morhua 85.19 0.00e+00 897.00
IUUC-Ggr-039915 Gaeumannomyces graminis 68.50 9.00e-136 477.00
IUUC-Gga-041176 Gallus gallus 81.40 0.00e+00 883.00
IUUC-Gac-042344 Gasterosteus aculeatus 85.96 0.00e+00 923.00
IUUC-Gma-042892 Glycine max 50.72 1.00e-132 466.00
IUUC-Ggo-044478 Gorilla gorilla 77.91 0.00e+00 832.00
IUUC-Hsa-046037 Homo sapiens 77.91 0.00e+00 833.00
IUUC-Hvu-047349 Hordeum vulgare 52.07 3.00e-136 478.00
IUUC-Itr-048390 Ictidomys tridecemlineatus 79.07 0.00e+00 848.00
IUUC-Kpa-049343 Komagataella pastoris 59.08 1.00e-119 423.00
IUUC-Lch-049830 Latimeria chalumnae 84.05 0.00e+00 914.00
IUUC-Lpe-051442 Leersia perrieri 49.69 4.00e-133 468.00
IUUC-Loc-051794 Lepisosteus oculatus 87.90 0.00e+00 912.00
IUUC-Lma-053137 Leptosphaeria maculans 46.48 8.00e-130 457.00
IUUC-Laf-053471 Loxodonta africana 78.40 0.00e+00 842.00
IUUC-Mcc-055627 Macaca mulatta 78.10 0.00e+00 836.00
IUUC-Meu-056148 Macropus eugenii 71.54 0.00e+00 754.00
IUUC-Mor-056960 Magnaporthe oryzae 67.79 3.00e-140 492.00
IUUC-Mtr-057816 Medicago truncatula 62.28 9.00e-129 453.00
IUUC-Mla-059031 Melampsora laricipopulina 63.94 2.00e-133 469.00
IUUC-Mga-059337 Meleagris gallopavo 81.91 0.00e+00 884.00
IUUC-Mvi-060217 Microbotryum violaceum 67.50 1.00e-134 473.00
IUUC-Mmr-061018 Microcebus murinus 79.07 0.00e+00 848.00
IUUC-Mdo-062863 Monodelphis domestica 79.46 0.00e+00 853.00
IUUC-Mmu-063988 Mus musculus 77.67 0.00e+00 831.00
IUUC-Mac-064459 Musa acuminata 66.56 5.00e-125 441.00
IUUC-Mpu-066559 Mustela putorius furo 79.07 0.00e+00 850.00
IUUC-Mlu-067361 Myotis lucifugus 79.34 0.00e+00 835.00
IUUC-Nfi-068492 Neosartorya fischeri 66.57 7.00e-135 474.00
IUUC-Ncr-068808 Neurospora crassa 67.28 2.00e-140 492.00
IUUC-Nle-069875 Nomascus leucogenys 78.10 0.00e+00 836.00
IUUC-Opr-070462 Ochotona princeps 89.85 8.00e-149 520.00
IUUC-Ont-071365 Oreochromis niloticus 85.96 0.00e+00 928.00
IUUC-Oan-072708 Ornithorhynchus anatinus 81.32 0.00e+00 880.00
IUUC-Ocu-074594 Oryctolagus cuniculus 78.10 0.00e+00 838.00
IUUC-Oba-075570 Oryza barthii 48.98 3.00e-131 461.00
IUUC-Obr-076366 Oryza brachyantha 66.95 1.00e-94 338.00
IUUC-Ogl-077153 Oryza glaberrima 48.78 3.00e-130 458.00
IUUC-Ogu-078540 Oryza glumaepatula 48.78 5.00e-131 461.00
IUUC-Oin-079612 Oryza indica 48.28 7.00e-129 454.00
IUUC-Olo-081077 Oryza longistaminata 48.28 7.00e-129 454.00
IUUC-Ome-081236 Oryza meridionalis 48.69 4.00e-128 451.00
IUUC-Oni-082499 Oryza nivara 48.78 5.00e-131 461.00
IUUC-Opu-083499 Oryza punctata 48.28 5.00e-129 454.00
IUUC-Oru-084276 Oryza rufipogon 48.78 5.00e-131 461.00
IUUC-Osa-085849 Oryza sativa 48.78 5.00e-131 461.00
IUUC-Ola-086655 Oryzias latipes 82.72 0.00e+00 885.00
IUUC-Olu-087637 Ostreococcus lucimarinus 55.20 2.00e-121 429.00
IUUC-Oga-087934 Otolemur garnettii 79.11 0.00e+00 847.00
IUUC-Oar-090185 Ovis aries 78.34 0.00e+00 839.00
IUUC-Ptr-091198 Pan troglodytes 78.10 0.00e+00 836.00
IUUC-Pan-092622 Papio anubis 77.91 0.00e+00 834.00
IUUC-Psi-093320 Pelodiscus sinensis 79.69 0.00e+00 872.00
IUUC-Pma-094638 Petromyzon marinus 78.45 0.00e+00 852.00
IUUC-Pno-094826 Phaeosphaeria nodorum 52.37 6.00e-107 380.00
IUUC-Ppa-095783 Physcomitrella patens 66.56 1.00e-126 447.00
IUUC-Pfo-096894 Poecilia formosa 84.85 0.00e+00 900.00
IUUC-Pab-098020 Pongo abelii 78.29 0.00e+00 837.00
IUUC-Pop-099180 Populus trichocarpa 49.50 2.00e-128 452.00
IUUC-Pca-100909 Procavia capensis 73.59 0.00e+00 658.00
IUUC-Ppe-101346 Prunus persica 47.28 5.00e-127 447.00
IUUC-Pva-102167 Pteropus vampyrus 65.50 0.00e+00 666.00
IUUC-Pgr-103516 Puccinia graminis 67.50 3.00e-133 468.00
IUUC-Ptt-103738 Puccinia triticina 51.16 1.00e-133 469.00
IUUC-Pte-104352 Pyrenophora teres 60.42 5.00e-133 468.00
IUUC-Pyt-104632 Pyrenophora triticirepentis 61.01 4.00e-134 471.00
IUUC-Rno-105291 Rattus norvegicus 77.91 0.00e+00 831.00
IUUC-Sce-106204 Saccharomyces cerevisiae 47.37 5.00e-104 371.00
IUUC-Sha-106943 Sarcophilus harrisii 78.92 0.00e+00 845.00
IUUC-Sja-107659 Schizosaccharomyces japonicus 65.54 2.00e-131 462.00
IUUC-Spo-108049 Schizosaccharomyces pombe 65.24 2.00e-136 478.00
IUUC-Smo-109043 Selaginella moellendorffii 62.84 2.00e-127 449.00
IUUC-Sit-110431 Setaria italica 51.23 7.00e-135 473.00
IUUC-Sly-111391 Solanum lycopersicum 63.90 2.00e-122 432.00
IUUC-Stu-112364 Solanum tuberosum 58.22 7.00e-100 357.00
IUUC-Sar-113450 Sorex araneus 88.83 0.00e+00 669.00
IUUC-Sbi-113829 Sorghum bicolor 50.81 2.00e-134 472.00
IUUC-Sre-115153 Sporisorium reilianum 61.38 1.00e-122 433.00
IUUC-Ssc-115798 Sus scrofa 78.34 0.00e+00 843.00
IUUC-Tgu-117417 Taeniopygia guttata 81.87 0.00e+00 883.00
IUUC-Tru-117615 Takifugu rubripes 82.39 0.00e+00 857.00
IUUC-Tsy-119480 Tarsius syrichta 78.95 0.00e+00 836.00
IUUC-Tni-119847 Tetraodon nigroviridis 83.79 0.00e+00 898.00
IUUC-Tca-121287 Theobroma cacao 48.67 4.00e-132 464.00
IUUC-Tre-122010 Trichoderma reesei 67.85 4.00e-146 511.00
IUUC-Tvi-122475 Trichoderma virens 66.96 2.00e-145 509.00
IUUC-Tae-124921 Triticum aestivum 51.87 2.00e-135 475.00
IUUC-Tur-126116 Triticum urartu 56.59 8.00e-102 363.00
IUUC-Tme-126992 Tuber melanosporum 67.68 7.00e-140 490.00
IUUC-Tbe-127803 Tupaia belangeri 71.56 6.00e-178 617.00
IUUC-Ttr-128933 Tursiops truncatus 78.83 0.00e+00 843.00
IUUC-Uma-129447 Ustilago maydis 60.50 4.00e-118 418.00
IUUC-Vda-129780 Verticillium dahliae 65.79 3.00e-141 495.00
IUUC-Vpa-130557 Vicugna pacos 63.91 3.00e-78 286.00
IUUC-Vvi-130918 Vitis vinifera 49.38 8.00e-125 440.00
IUUC-Xtr-132409 Xenopus tropicalis 81.36 0.00e+00 848.00
IUUC-Xma-133420 Xiphophorus maculatus 84.41 0.00e+00 898.00
IUUC-Yli-134362 Yarrowia lipolytica 53.90 9.00e-125 440.00
IUUC-Zma-135804 Zea mays 63.13 1.00e-127 449.00
Created Date 25-Jun-2017

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