iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tvi-122661

Ensembl Protein ID

EHK23518

UniProt Accession

G9MNR3; G9MNR3_HYPVG

Genbank Protein ID

EHK23518.1

Protein Name

Nuclear distribution protein PAC1; Lissencephaly-1 homolog; nudF homolog

Genbank Nucleotide ID

ABDF02000005

Gene Name

PAC1; LIS1; TRIVIDRAFT_190487

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIVIDRAFT_190487	EHK23518	EHK23518

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-47	157.3	115	152
UBD/Beta-Prp	3.90e-64	216.0	113	465

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H +svtc+af +  t l+sGs D+tikvWD+  g+l++
   Q: 115  HRASVTCVAFhPRfTSLASGSEDCTIKVWDWELGDLEQ 152
           999*******988899**************98888777 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk..ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfsp 104
           ++h + +tcv+f+p  + la+gs+d tikvwd++ g+l ++++gh+ +v ++++   +   +l+++s+D tik+wd+   +k ++tl+ghe+sv +++f p
   Q: 113  ESHRASVTCVAFHPRFTSLASGSEDCTIKVWDWELGDLEQTIKGHTRPVLDLDYGGPKTgiLLASCSSDTTIKLWDPAdGYKNIRTLSGHEHSVSAVRFIP 213
           456667888*********************************************87766679*************765489***************88888 PP
   S: 105  ........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..ktgkllrtltgghtdsvyslsfdsng... 192
                   sg+ lvsG  d+t+++wd +tg+c++ tl+gh g+v+ v+ + dgn+l s + D t rlW l  ++ +   tl g h++ v + +f +     
   Q: 214  sggtgffsSGNMLVSGCGDKTLKIWDANTGYCVK-TLNGHAGWVRDVCPSLDGNYLLSTGGDHTGRLWELtvANPETKVTLIG-HEHVVGCCAFAPPAaye 312
           7777777688************************.**********************************97777777788898.*********77766677 PP
   S: 193  ..................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl.rsgdllktlqlhn.......... 264
                             +++++gs+d+t+klwd  +g+c++tl+gh+++v+ v f+p +++l+s+++D+s+r+Wdl + g++++tl+  +          
   Q: 313  hlaalaglkkpppatstsEFMATGSRDKTIKLWDA-RGNCIKTLIGHDNWVSGVMFHPGGKYLLSVADDKSLRCWDLsQDGKCVRTLSSAHehfitslrwa 412
           777777777777777777****************9.899************************************983568*******9995444444444 PP
   S: 265  ...........ssvisvavlsfgdnvl............................vlgsedskvniw 292
                                                                  ++gs d +v+iw
   Q: 413  pakpkdtptgnG--------------TanndsentprraaaaaldisdaqircviATGSVDMTVKIW 465
           444444444440..............14444444445555555555555555555888888888888 PP

Organism

Trichoderma virens

Functional Description
(View)

Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.

Protein Sequence
(Fasta)

MSRTLPARQA EELHKSIIAY LAANNLANTA TVLREELDLG EDVFDATMTK KYETLLEKKW 60
TSIVRLQKKI MDLETRNAEL QSEVDNATPS SLSQKNKDPA SWLPKAPSRH TLESHRASVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTCGAA CACTGCCCGC CCGGCAGGCC GAGGAGCTGT AGGTATATGG CCACTGTTTA 60
CAAGGGTGGC GGAGGGGCAC AGGACGACTT TGGAGAGAGG CTGGAGACGG AAGACATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0000132--P:establishment of mitotic spindle orientation
GO:0007067--P:mitotic nuclear division
GO:0006810--P:transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001589	Ailuropoda melanoleuca	43.70	2.00e-102	363.00
IUUC-Apl-004024	Anas platyrhynchos	44.23	1.00e-105	374.00
IUUC-Aca-004564	Anolis carolinensis	43.80	5.00e-103	365.00
IUUC-Ago-007862	Ashbya gossypii	28.12	3.00e-35	141.00
IUUC-Acl-008360	Aspergillus clavatus	64.89	1.00e-172	597.00
IUUC-Afl-008502	Aspergillus flavus	60.53	3.00e-165	572.00
IUUC-Afu-008848	Aspergillus fumigatus	64.98	0.00e+00	627.00
IUUC-Ani-009173	Aspergillus nidulans	57.39	1.00e-154	537.00
IUUC-Ang-009873	Aspergillus niger	55.91	1.00e-152	531.00
IUUC-Aor-009973	Aspergillus oryzae	57.60	2.00e-157	546.00
IUUC-Ate-010523	Aspergillus terreus	54.84	5.00e-152	528.00
IUUC-Ame-011154	Astyanax mexicanus	44.26	8.00e-107	378.00
IUUC-Bgr-011972	Blumeria graminis	63.38	0.00e+00	632.00
IUUC-Bta-013106	Bos taurus	43.83	3.00e-105	373.00
IUUC-Bci-013615	Botrytis cinerea	65.52	0.00e+00	640.00
IUUC-Cel-018459	Caenorhabditis elegans	37.58	4.00e-87	313.00
IUUC-Cja-018755	Callithrix jacchus	43.07	1.00e-102	364.00
IUUC-Cfa-020749	Canis familiaris	43.83	3.00e-105	373.00
IUUC-Cpo-022371	Cavia porcellus	43.83	3.00e-105	373.00
IUUC-Csa-023524	Chlorocebus sabaeus	43.89	3.00e-88	317.00
IUUC-Cho-024764	Choloepus hoffmanni	40.67	6.00e-85	305.00
IUUC-Cin-025753	Ciona intestinalis	41.81	2.00e-94	337.00
IUUC-Csv-025817	Ciona savignyi	42.03	4.00e-99	352.00
IUUC-Cgl-026529	Colletotrichum gloeosporioides	68.52	0.00e+00	649.00
IUUC-Cne-027087	Cryptococcus neoformans	50.12	3.00e-107	380.00
IUUC-Dre-028314	Danio rerio	44.02	2.00e-104	370.00
IUUC-Dno-029050	Dasypus novemcinctus	43.83	3.00e-105	373.00
IUUC-Dor-030222	Dipodomys ordii	40.52	2.00e-94	337.00
IUUC-Dse-031164	Dothistroma septosporum	59.49	2.00e-170	590.00
IUUC-Dme-031745	Drosophila melanogaster	40.99	8.00e-91	325.00
IUUC-Ete-032508	Echinops telfairi	43.64	3.00e-71	260.00
IUUC-Eca-034288	Equus caballus	43.26	3.00e-101	360.00
IUUC-Eeu-034984	Erinaceus europaeus	40.30	2.00e-93	334.00
IUUC-Fca-036498	Felis catus	43.83	3.00e-105	373.00
IUUC-Fal-036920	Ficedula albicollis	44.23	1.00e-105	374.00
IUUC-Fox-037996	Fusarium oxysporum	68.03	0.00e+00	675.00
IUUC-Fso-038160	Fusarium solani	65.52	0.00e+00	648.00
IUUC-Gmo-038983	Gadus morhua	43.83	7.00e-105	372.00
IUUC-Ggr-040051	Gaeumannomyces graminis	65.38	0.00e+00	637.00
IUUC-Gga-040623	Gallus gallus	44.23	1.00e-105	374.00
IUUC-Gac-041613	Gasterosteus aculeatus	43.20	4.00e-104	369.00
IUUC-Ggo-045410	Gorilla gorilla	42.11	1.00e-83	301.00
IUUC-Hsa-046358	Homo sapiens	44.02	4.00e-105	373.00
IUUC-Itr-047890	Ictidomys tridecemlineatus	43.83	3.00e-105	373.00
IUUC-Kpa-049351	Komagataella pastoris	27.83	7.00e-46	176.00
IUUC-Lch-049936	Latimeria chalumnae	43.19	2.00e-104	370.00
IUUC-Loc-052476	Lepisosteus oculatus	44.35	1.00e-103	367.00
IUUC-Lma-053170	Leptosphaeria maculans	62.88	2.00e-169	586.00
IUUC-Laf-053713	Loxodonta africana	43.84	2.00e-103	367.00
IUUC-Mcc-054628	Macaca mulatta	43.83	5.00e-105	372.00
IUUC-Meu-055927	Macropus eugenii	38.48	3.00e-54	203.00
IUUC-Mor-056962	Magnaporthe oryzae	66.38	0.00e+00	652.00
IUUC-Mpo-057583	Magnaporthe poae	66.45	1.00e-179	620.00
IUUC-Mla-058819	Melampsora laricipopulina	43.76	4.00e-105	373.00
IUUC-Mga-059945	Meleagris gallopavo	44.02	3.00e-105	373.00
IUUC-Mvi-060403	Microbotryum violaceum	47.87	2.00e-119	420.00
IUUC-Mmr-061289	Microcebus murinus	43.70	2.00e-102	363.00
IUUC-Mdo-061912	Monodelphis domestica	43.62	2.00e-104	370.00
IUUC-Mmu-063253	Mus musculus	43.83	3.00e-105	373.00
IUUC-Mpu-066638	Mustela putorius furo	43.83	3.00e-105	373.00
IUUC-Mlu-067267	Myotis lucifugus	43.07	1.00e-102	365.00
IUUC-Nfi-068571	Neosartorya fischeri	61.43	3.00e-165	573.00
IUUC-Ncr-068895	Neurospora crassa	69.59	0.00e+00	652.00
IUUC-Nle-069087	Nomascus leucogenys	45.15	5.00e-83	299.00
IUUC-Opr-070579	Ochotona princeps	43.83	3.00e-105	373.00
IUUC-Ont-072432	Oreochromis niloticus	43.59	9.00e-105	372.00
IUUC-Oan-073072	Ornithorhynchus anatinus	43.83	3.00e-105	373.00
IUUC-Ocu-074180	Oryctolagus cuniculus	43.83	3.00e-105	373.00
IUUC-Ola-086815	Oryzias latipes	43.83	3.00e-105	373.00
IUUC-Oga-088219	Otolemur garnettii	43.32	1.00e-102	364.00
IUUC-Oar-090394	Ovis aries	43.83	3.00e-105	373.00
IUUC-Ptr-091517	Pan troglodytes	43.83	3.00e-105	373.00
IUUC-Pan-092421	Papio anubis	43.83	5.00e-105	372.00
IUUC-Psi-093370	Pelodiscus sinensis	44.02	8.00e-105	372.00
IUUC-Pma-094319	Petromyzon marinus	42.11	3.00e-85	306.00
IUUC-Pno-094815	Phaeosphaeria nodorum	61.88	2.00e-173	600.00
IUUC-Pfo-097089	Poecilia formosa	44.02	4.00e-105	373.00
IUUC-Pab-098421	Pongo abelii	43.83	3.00e-105	373.00
IUUC-Pca-100120	Procavia capensis	38.59	4.00e-59	220.00
IUUC-Pva-102960	Pteropus vampyrus	43.62	5.00e-104	369.00
IUUC-Pgr-103538	Puccinia graminis	45.45	1.00e-113	401.00
IUUC-Ptt-103990	Puccinia triticina	39.08	9.00e-37	147.00
IUUC-Pte-104261	Pyrenophora teres	63.17	3.00e-174	602.00
IUUC-Pyt-104780	Pyrenophora triticirepentis	63.38	1.00e-174	604.00
IUUC-Rno-105123	Rattus norvegicus	43.83	3.00e-105	373.00
IUUC-Sce-106208	Saccharomyces cerevisiae	28.40	1.00e-36	145.00
IUUC-Sha-107010	Sarcophilus harrisii	43.62	1.00e-104	371.00
IUUC-Sja-107899	Schizosaccharomyces japonicus	34.96	2.00e-66	244.00
IUUC-Ssl-108571	Sclerotinia sclerotiorum	66.52	8.00e-180	621.00
IUUC-Sar-113309	Sorex araneus	43.26	1.00e-100	358.00
IUUC-Sre-115003	Sporisorium reilianum	48.28	2.00e-121	427.00
IUUC-Ssc-116148	Sus scrofa	43.83	3.00e-105	373.00
IUUC-Tgu-117299	Taeniopygia guttata	43.80	2.00e-105	374.00
IUUC-Tru-118179	Takifugu rubripes	44.04	5.00e-105	372.00
IUUC-Tsy-119493	Tarsius syrichta	43.19	9.00e-104	368.00
IUUC-Tni-120355	Tetraodon nigroviridis	43.20	9.00e-103	365.00
IUUC-Tre-121977	Trichoderma reesei	92.48	0.00e+00	854.00
IUUC-Tme-127031	Tuber melanosporum	61.12	1.00e-169	587.00
IUUC-Tbe-127492	Tupaia belangeri	43.21	4.00e-50	190.00
IUUC-Ttr-128929	Tursiops truncatus	43.83	5.00e-105	372.00
IUUC-Uma-129347	Ustilago maydis	48.29	2.00e-117	414.00
IUUC-Vda-129837	Verticillium dahliae	66.17	3.00e-175	606.00
IUUC-Vpa-130532	Vicugna pacos	41.18	8.00e-84	302.00
IUUC-Xtr-131985	Xenopus tropicalis	43.40	1.00e-104	371.00
IUUC-Xma-133314	Xiphophorus maculatus	44.02	3.00e-105	373.00
IUUC-Yli-134403	Yarrowia lipolytica	39.14	4.00e-91	326.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence