iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041628

UUCD1 version

UUC-GaA-00624

Ensembl Protein ID

ENSGACP00000016134.1

UniProt Accession

G3PEW0; G3PEW0_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000012187.1	ENSGACT00000016165.1	ENSGACP00000016134.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	2.50e-96	324.2	980	1492

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 70   nreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveL 156
            ++W+ f+eql+  + +f      y  k           +++w +e++ed k +ll+l  kl+ a+R+++++++r+l++ +++    
   Q: 980  PTFWPVFKEQLCCRTYLF------YSTK-----------AHTWCQEVMED-KMQLLQLFNKLNSALRHEQMFADRFLPDPEAA---- 1044
           589***************......9999...........***********.********************************.... PP
   S: 157  slnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllae 242
               +a++++++Ea+  + ++ ++ +es++ +   + ++eYl+++e+  + ++++a + ++++++t+Ll++v+   +    e+l ++
   Q: 1045 ----EALGRTCWEALITPIVHSITLPESSAPSPLsWLLSEYLRNAESTRRCKSRAAIFNSRVRRLTHLLVHVDTSRLD--SEELKPP 1125
           ....9****************************99****************************************999..899**** PP
   S: 243  lvallrdkktedlsrmykLlsrvln.gleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlka 328
           +++  ++ k+++    +    r +  ++  ++ +++ +++ q+k++l+++    d   +Ver+ +l+ +l+++++e+F+++++F+ a
   Q: 1126 VKSNGKEGKNKETPAASLAKPRLKSsSIAGIALCWQGVVQRQVKKFLESSCSLPD---FVERYRTLYLRLKNAMEELFGQQTAFVLA 1209
           ***999999999999988888888899****************************...***************************** PP
   S: 329  ldkafetfvnknsvlkaakspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLlsgksass 412
           l+++f++++++ s+l+a +++E +++yiD+ +++s     + e +++l+++l+ + ++s++++   Fe++Y+ +L +RLl       
   Q: 1210 LRHGFSSALLQLSILRAMHVSERFSQYIDSTIQASGAASGSTETLQRLQQFLEPMLFLSGLELantFEHFYRYYLGDRLLA--QGNV 1294
           ***********************************99999*****************************************..99** PP
   S: 413  eaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk.............................eekenteesesvelsvl 469
           ++E +vi ++    g +f+s+  ++M+++l+ S +l+++F+                             ee  ++ e+++ e++vl
   Q: 1295 WLESAVIDQI----GSCFPSRFpQQMLKNLSESAELQQEFHlyrlqqldrclqehdqvgknppnrlqimeEEWVESDEETEAEVQVL 1377
           **********....******************************************************9767777888899****** PP
   S: 470  vLsagaWpta....setekvsLPaelektiekfeefY........lekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLL 544
           vLs+++W+++     + ++ + P+el+ ++++f++fY        l++ + R+LqW++ lg+ael++    g  +l+Vst+Qm +LL
   Q: 1378 VLSPRCWAVSslcfLDEPTKHFPEELCSYLDQFTQFYshsqsmlgLSHWKPRRLQWTW-LGHAELQF----GCLKLHVSTLQMFILL 1459
           *********9885545599************************999999*********.********....99************** PP
   S: 545  afnnsekvsveelkkatelpeeeLrrtlqsLvs 577
           ++n +++v ve l kat+l++++L  +lq+L+s
   Q: 1460 QLNSHQEVPVEALLKATGLSAAVLLHALQPLIS 1492
           *******************************98 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MVGERRNGNL LVQLGPRLQA YPEELIRQRR NHDGQTEYLI RWCLVTSGSD GAAGPASGES 60
KPENILMWMS TEDVYANCPG LLGKRKTDVQ RPLQLEAGHD VTFDEVELSD MKDDVKNLVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGGCG AGCGGCGCAA TGGGAACCTG CTGGTCCAGC TGGGCCCGAG GCTGCAGGCC 60
TATCCGGAGG AGCTGATCCG CCAGCGCCGC AACCACGACG GCCAGACGGA GTACCTGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021097--CPH_domain
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2
PS51284--DOC

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM01337--APC10
SM00884--Cullin_Nedd8

Gene Ontology

GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002360	Ailuropoda melanoleuca	46.38	0.00e+00	1305.00
IUUC-Apl-003458	Anas platyrhynchos	51.08	9.00e-94	339.00
IUUC-Aca-004815	Anolis carolinensis	65.83	0.00e+00	1173.00
IUUC-Ame-010611	Astyanax mexicanus	75.20	0.00e+00	1454.00
IUUC-Bta-013285	Bos taurus	46.69	0.00e+00	1134.00
IUUC-Cja-019033	Callithrix jacchus	44.46	0.00e+00	1273.00
IUUC-Cfa-020119	Canis familiaris	54.72	0.00e+00	958.00
IUUC-Cpo-021513	Cavia porcellus	47.41	0.00e+00	824.00
IUUC-Csa-023798	Chlorocebus sabaeus	46.00	0.00e+00	1310.00
IUUC-Cho-024879	Choloepus hoffmanni	46.24	5.00e-82	300.00
IUUC-Cin-025402	Ciona intestinalis	33.60	1.00e-115	411.00
IUUC-Dno-028904	Dasypus novemcinctus	55.36	0.00e+00	949.00
IUUC-Dor-030234	Dipodomys ordii	48.32	0.00e+00	898.00
IUUC-Ete-032516	Echinops telfairi	59.76	1.00e-149	525.00
IUUC-Eca-033408	Equus caballus	45.64	0.00e+00	1250.00
IUUC-Eeu-035166	Erinaceus europaeus	52.85	0.00e+00	749.00
IUUC-Fca-035483	Felis catus	45.48	0.00e+00	1291.00
IUUC-Fal-036672	Ficedula albicollis	57.50	0.00e+00	1051.00
IUUC-Gmo-038795	Gadus morhua	64.07	0.00e+00	1785.00
IUUC-Gga-040154	Gallus gallus	51.45	7.00e-105	376.00
IUUC-Ggo-044721	Gorilla gorilla	55.69	0.00e+00	734.00
IUUC-Hsa-046406	Homo sapiens	47.72	0.00e+00	1156.00
IUUC-Itr-048525	Ictidomys tridecemlineatus	50.67	0.00e+00	888.00
IUUC-Lch-049956	Latimeria chalumnae	73.88	0.00e+00	1051.00
IUUC-Loc-052706	Lepisosteus oculatus	75.60	0.00e+00	1500.00
IUUC-Laf-054068	Loxodonta africana	49.95	0.00e+00	892.00
IUUC-Mcc-055464	Macaca mulatta	45.77	0.00e+00	1311.00
IUUC-Meu-056198	Macropus eugenii	47.69	0.00e+00	1302.00
IUUC-Mga-059683	Meleagris gallopavo	56.05	2.00e-110	392.00
IUUC-Mmr-061464	Microcebus murinus	44.98	0.00e+00	1280.00
IUUC-Mdo-062902	Monodelphis domestica	62.85	0.00e+00	818.00
IUUC-Mmu-063413	Mus musculus	44.80	0.00e+00	1033.00
IUUC-Mpu-066146	Mustela putorius furo	46.73	0.00e+00	1254.00
IUUC-Mlu-067036	Myotis lucifugus	45.17	0.00e+00	1284.00
IUUC-Nle-069292	Nomascus leucogenys	59.48	0.00e+00	752.00
IUUC-Opr-070670	Ochotona princeps	43.57	0.00e+00	1206.00
IUUC-Ont-071953	Oreochromis niloticus	83.06	0.00e+00	1626.00
IUUC-Oan-073451	Ornithorhynchus anatinus	48.77	0.00e+00	1146.00
IUUC-Ocu-074155	Oryctolagus cuniculus	44.84	0.00e+00	1230.00
IUUC-Ola-087072	Oryzias latipes	82.33	0.00e+00	1637.00
IUUC-Oga-089084	Otolemur garnettii	44.81	0.00e+00	1279.00
IUUC-Oar-090029	Ovis aries	47.68	0.00e+00	1152.00
IUUC-Ptr-091282	Pan troglodytes	46.55	0.00e+00	1137.00
IUUC-Pan-091883	Papio anubis	45.89	0.00e+00	1318.00
IUUC-Pma-094192	Petromyzon marinus	49.20	0.00e+00	922.00
IUUC-Pfo-096773	Poecilia formosa	69.70	0.00e+00	814.00
IUUC-Pab-098383	Pongo abelii	45.72	0.00e+00	1104.00
IUUC-Pca-100539	Procavia capensis	53.19	8.00e-155	542.00
IUUC-Pva-102417	Pteropus vampyrus	44.53	0.00e+00	1020.00
IUUC-Rno-105962	Rattus norvegicus	45.19	0.00e+00	1094.00
IUUC-Sha-106896	Sarcophilus harrisii	68.55	2.00e-147	518.00
IUUC-Sar-113132	Sorex araneus	63.52	3.00e-142	500.00
IUUC-Ssc-115899	Sus scrofa	55.86	0.00e+00	716.00
IUUC-Tgu-116915	Taeniopygia guttata	61.20	2.00e-147	515.00
IUUC-Tru-118013	Takifugu rubripes	80.93	0.00e+00	1536.00
IUUC-Tsy-118860	Tarsius syrichta	52.58	0.00e+00	648.00
IUUC-Tni-120062	Tetraodon nigroviridis	81.81	0.00e+00	1538.00
IUUC-Tbe-127660	Tupaia belangeri	44.42	0.00e+00	705.00
IUUC-Ttr-128973	Tursiops truncatus	46.12	0.00e+00	888.00
IUUC-Vpa-130086	Vicugna pacos	45.09	2.00e-160	560.00
IUUC-Xtr-132882	Xenopus tropicalis	57.82	0.00e+00	1052.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence