iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000001573.1	ENSSHAT00000001782.1	ENSSHAP00000001764.1
ENSSHAG00000001573.1	ENSSHAT00000001783.1	ENSSHAP00000001765.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-28	96.5	184	217
UBD/Beta-Prp	9.90e-50	169.5	42	281

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH  ++ ++++ +    +l+++s D ++k+WD+r
   Q: 184  GHRQEILAVSWsPRyeYILATASADSKVKLWDIR 217
           89*********94344668*************87 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgk.ilvtgseDrtikvwdls........tgkcvhtlk.....ghedsvlslsfsp.sgdklvsGshdrtirvwdle 124
           h+++v++++++p +  ++++g++D++i ++dl+        t+k v ++       h++sv +++++p ++  + s s d+t+++wd++
   Q: 42   HSNGVNTLDIEPVEGrYMLSGGSDGIIVLYDLEnfsrkvhyTCKAVCSVGrnhpdVHKYSVETVQWYPhDTGMFTSSSFDKTLKIWDTN 130
           99**********98779****************66666655444444444878888999*********777****************** PP
   S: 125  tgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq. 210
           t q+   ++ ++++      + +++ ++++ G++  +v+l dlk+g++ + l+g h + +  +s+++     l+++s d++vklwd++ 
   Q: 131  TLQVTDYFFFPNTAYYFEYFSVCTQhRIVAVGTKGPKVQLCDLKSGSCSHILQG-HRQEILAVSWSPRYeYILATASADSKVKLWDIRr 218
           *****998999998888888888887***************************9.************885667899************8 PP
   S: 211  ...........tgec.......vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
                      +            + ++h+  v+ + f++++ +l++++ D   r+W++ sg+++
   Q: 219  asgclitldqhN--GekskassEAANTAHNGRVNGLCFTRDGLHLLTTGTDDRMRLWNSSSGENT 281
           644444444441..0334444456666666*******************************9987 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MLNFLEARQA GLDDPGRLRR AEATRRVLKL ELNKDREVER IHSNGVNTLD IEPVEGRYML 60
SGGSDGIIVL YDLENFSRKV HYTCKAVCSV GRNHPDVHKY SVETVQWYPH DTGMFTSSSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGAACT TCCTGGAGGC GCGGCAAGCG GGTCTGGACG ATCCTGGGAG GCTTCGGAGA 60
GCGGAGGCCA CCCGGAGGTA AAGAGAGCCC GAGAAGCCGG TCAGGGTCAG CGGTTCTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	29.23	2.00e-34	140.00
IUUC-Aml-002201	Ailuropoda melanoleuca	82.91	0.00e+00	692.00
IUUC-Atr-002784	Amborella trichopoda	37.02	1.00e-41	164.00
IUUC-Apl-003202	Anas platyrhynchos	78.48	0.00e+00	654.00
IUUC-Aca-004708	Anolis carolinensis	80.46	3.00e-175	607.00
IUUC-Aly-006144	Arabidopsis lyrata	34.15	4.00e-67	248.00
IUUC-Ath-006673	Arabidopsis thaliana	39.15	2.00e-44	173.00
IUUC-Acl-008195	Aspergillus clavatus	35.37	5.00e-42	165.00
IUUC-Afl-008406	Aspergillus flavus	36.03	1.00e-36	146.00
IUUC-Afu-008759	Aspergillus fumigatus	33.22	3.00e-37	149.00
IUUC-Ani-009380	Aspergillus nidulans	34.44	2.00e-40	159.00
IUUC-Ang-009820	Aspergillus niger	34.17	1.00e-35	143.00
IUUC-Aor-010092	Aspergillus oryzae	35.84	1.00e-41	164.00
IUUC-Ate-010491	Aspergillus terreus	35.94	1.00e-42	167.00
IUUC-Bta-012825	Bos taurus	82.66	0.00e+00	694.00
IUUC-Bci-013856	Botrytis cinerea	31.08	4.00e-50	192.00
IUUC-Bdi-014899	Brachypodium distachyon	32.18	5.00e-59	221.00
IUUC-Bol-015337	Brassica oleracea	32.36	1.00e-66	247.00
IUUC-Bra-018089	Brassica rapa	32.36	2.00e-67	249.00
IUUC-Cja-018725	Callithrix jacchus	81.66	0.00e+00	678.00
IUUC-Cfa-021162	Canis familiaris	83.17	0.00e+00	692.00
IUUC-Cpo-022190	Cavia porcellus	82.66	0.00e+00	687.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	34.76	2.00e-37	150.00
IUUC-Csa-023610	Chlorocebus sabaeus	82.41	0.00e+00	690.00
IUUC-Cho-024689	Choloepus hoffmanni	82.26	0.00e+00	634.00
IUUC-Cin-025324	Ciona intestinalis	39.01	2.00e-76	279.00
IUUC-Csv-026059	Ciona savignyi	37.15	1.00e-70	259.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	34.17	1.00e-36	147.00
IUUC-Cme-027182	Cyanidioschyzon merolae	26.83	2.00e-12	67.80
IUUC-Dre-028696	Danio rerio	72.39	2.00e-176	611.00
IUUC-Dno-029102	Dasypus novemcinctus	82.91	0.00e+00	692.00
IUUC-Dor-030361	Dipodomys ordii	67.84	3.00e-155	540.00
IUUC-Dse-031167	Dothistroma septosporum	28.54	5.00e-44	171.00
IUUC-Ete-032856	Echinops telfairi	71.61	2.00e-166	577.00
IUUC-Eca-033611	Equus caballus	83.24	7.00e-171	592.00
IUUC-Eeu-034583	Erinaceus europaeus	61.31	2.00e-133	468.00
IUUC-Fca-036481	Felis catus	81.66	0.00e+00	681.00
IUUC-Fal-037327	Ficedula albicollis	78.53	2.00e-163	567.00
IUUC-Fox-037684	Fusarium oxysporum	32.07	2.00e-40	159.00
IUUC-Fso-038306	Fusarium solani	33.60	5.00e-50	191.00
IUUC-Gmo-039043	Gadus morhua	67.93	3.00e-164	571.00
IUUC-Ggr-039783	Gaeumannomyces graminis	26.80	4.00e-34	139.00
IUUC-Gga-041085	Gallus gallus	84.20	2.00e-179	621.00
IUUC-Gac-042328	Gasterosteus aculeatus	68.73	3.00e-161	561.00
IUUC-Gma-043004	Glycine max	34.03	2.00e-59	222.00
IUUC-Ggo-045627	Gorilla gorilla	75.62	0.00e+00	626.00
IUUC-Hsa-046028	Homo sapiens	82.41	0.00e+00	690.00
IUUC-Hvu-047678	Hordeum vulgare	27.94	7.00e-29	120.00
IUUC-Itr-048648	Ictidomys tridecemlineatus	82.16	0.00e+00	691.00
IUUC-Kpa-049386	Komagataella pastoris	32.59	1.00e-44	174.00
IUUC-Lch-050590	Latimeria chalumnae	76.72	8.00e-156	542.00
IUUC-Lpe-051725	Leersia perrieri	32.46	7.00e-35	141.00
IUUC-Loc-051788	Lepisosteus oculatus	75.26	2.00e-180	625.00
IUUC-Lma-053082	Leptosphaeria maculans	33.67	3.00e-52	199.00
IUUC-Laf-053809	Loxodonta africana	82.91	0.00e+00	694.00
IUUC-Mcc-054998	Macaca mulatta	81.91	2.00e-139	487.00
IUUC-Meu-055929	Macropus eugenii	84.67	0.00e+00	689.00
IUUC-Mor-057003	Magnaporthe oryzae	31.85	1.00e-41	164.00
IUUC-Mtr-057921	Medicago truncatula	31.15	4.00e-59	221.00
IUUC-Mga-059449	Meleagris gallopavo	63.93	1.00e-117	416.00
IUUC-Mmr-061609	Microcebus murinus	80.15	0.00e+00	641.00
IUUC-Mdo-062564	Monodelphis domestica	91.21	0.00e+00	759.00
IUUC-Mmu-063904	Mus musculus	80.15	0.00e+00	673.00
IUUC-Mac-064716	Musa acuminata	30.00	3.00e-50	192.00
IUUC-Mpu-066617	Mustela putorius furo	82.41	0.00e+00	682.00
IUUC-Mlu-067054	Myotis lucifugus	82.16	0.00e+00	680.00
IUUC-Nfi-068467	Neosartorya fischeri	33.09	1.00e-33	136.00
IUUC-Nle-069731	Nomascus leucogenys	82.41	0.00e+00	690.00
IUUC-Opr-070297	Ochotona princeps	56.36	6.00e-68	251.00
IUUC-Ont-072558	Oreochromis niloticus	71.07	2.00e-167	581.00
IUUC-Oan-072864	Ornithorhynchus anatinus	83.33	7.00e-24	101.00
IUUC-Ocu-074415	Oryctolagus cuniculus	82.91	0.00e+00	692.00
IUUC-Oba-075759	Oryza barthii	35.45	2.00e-41	162.00
IUUC-Obr-076387	Oryza brachyantha	35.32	5.00e-44	171.00
IUUC-Ogl-077924	Oryza glaberrima	42.22	6.00e-20	90.50
IUUC-Ogu-078186	Oryza glumaepatula	33.78	4.00e-62	231.00
IUUC-Oin-079389	Oryza indica	32.94	9.00e-45	174.00
IUUC-Olo-080916	Oryza longistaminata	29.12	3.00e-13	68.20
IUUC-Ome-081471	Oryza meridionalis	34.55	4.00e-38	152.00
IUUC-Oni-082449	Oryza nivara	35.00	2.00e-38	153.00
IUUC-Opu-083210	Oryza punctata	29.95	3.00e-56	212.00
IUUC-Oru-085159	Oryza rufipogon	35.45	2.00e-41	163.00
IUUC-Osa-085926	Oryza sativa	37.01	5.00e-30	123.00
IUUC-Ola-087084	Oryzias latipes	69.02	2.00e-168	584.00
IUUC-Olu-087853	Ostreococcus lucimarinus	29.60	1.00e-40	160.00
IUUC-Oga-089008	Otolemur garnettii	80.20	0.00e+00	681.00
IUUC-Oar-089259	Ovis aries	82.91	0.00e+00	694.00
IUUC-Ptr-091112	Pan troglodytes	82.03	0.00e+00	682.00
IUUC-Pan-092303	Papio anubis	84.50	4.00e-63	232.00
IUUC-Psi-093050	Pelodiscus sinensis	82.96	0.00e+00	688.00
IUUC-Pma-094259	Petromyzon marinus	55.45	2.00e-123	435.00
IUUC-Pno-094798	Phaeosphaeria nodorum	31.92	4.00e-49	188.00
IUUC-Ppa-095477	Physcomitrella patens	29.67	5.00e-49	188.00
IUUC-Pfo-096855	Poecilia formosa	68.91	5.00e-169	587.00
IUUC-Pab-098096	Pongo abelii	81.91	0.00e+00	684.00
IUUC-Pop-098800	Populus trichocarpa	30.59	6.00e-65	241.00
IUUC-Pca-100187	Procavia capensis	83.01	2.00e-98	352.00
IUUC-Ppe-101759	Prunus persica	35.81	7.00e-43	167.00
IUUC-Pva-102438	Pteropus vampyrus	68.29	3.00e-77	281.00
IUUC-Pte-104197	Pyrenophora teres	32.77	5.00e-48	185.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	32.67	2.00e-47	183.00
IUUC-Rno-106087	Rattus norvegicus	80.65	0.00e+00	685.00
IUUC-Sce-106276	Saccharomyces cerevisiae	25.00	2.00e-11	63.90
IUUC-Sja-107681	Schizosaccharomyces japonicus	30.87	4.00e-49	188.00
IUUC-Spo-108294	Schizosaccharomyces pombe	34.68	6.00e-59	221.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	33.06	4.00e-51	195.00
IUUC-Smo-109008	Selaginella moellendorffii	37.80	2.00e-73	269.00
IUUC-Sit-110300	Setaria italica	29.74	2.00e-52	199.00
IUUC-Sly-111441	Solanum lycopersicum	32.63	5.00e-58	218.00
IUUC-Stu-111995	Solanum tuberosum	32.40	5.00e-59	221.00
IUUC-Sar-113196	Sorex araneus	71.48	6.00e-106	377.00
IUUC-Sbi-113790	Sorghum bicolor	31.04	2.00e-51	196.00
IUUC-Ssc-115609	Sus scrofa	83.17	0.00e+00	689.00
IUUC-Tgu-116927	Taeniopygia guttata	80.20	0.00e+00	653.00
IUUC-Tru-118164	Takifugu rubripes	69.83	3.00e-174	604.00
IUUC-Tsy-119151	Tarsius syrichta	75.88	2.00e-180	624.00
IUUC-Tni-120896	Tetraodon nigroviridis	68.75	2.00e-163	568.00
IUUC-Tca-121592	Theobroma cacao	30.80	9.00e-63	234.00
IUUC-Tre-122023	Trichoderma reesei	33.54	9.00e-44	171.00
IUUC-Tvi-122507	Trichoderma virens	32.18	3.00e-45	176.00
IUUC-Tae-125730	Triticum aestivum	29.93	1.00e-52	200.00
IUUC-Tur-126092	Triticum urartu	29.58	6.00e-31	128.00
IUUC-Tbe-127422	Tupaia belangeri	62.37	2.00e-127	448.00
IUUC-Ttr-129097	Tursiops truncatus	80.65	0.00e+00	672.00
IUUC-Vda-130014	Verticillium dahliae	36.05	2.00e-46	180.00
IUUC-Vpa-130782	Vicugna pacos	82.16	0.00e+00	689.00
IUUC-Vvi-131494	Vitis vinifera	31.84	4.00e-65	241.00
IUUC-Xtr-132165	Xenopus tropicalis	78.11	0.00e+00	628.00
IUUC-Xma-133205	Xiphophorus maculatus	69.33	2.00e-170	591.00
IUUC-Yli-134614	Yarrowia lipolytica	33.92	1.00e-55	210.00
IUUC-Zma-135861	Zea mays	33.98	5.00e-60	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence