iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-14	55.0	267	306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH + vtcl+  +d   l+sGs+D ++++WD+++  +l++
   Q: 267  GHRNQVTCLSVsTDgSVLLSGSHDESVRLWDVKSKQCLRT 306
           8**********988899****************9999875 PP

Organism

Mus musculus

Functional Description
(View)

May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Protein Sequence
(Fasta)

MAAPMEVVVC TDAAAQLWSC VVWELHSGAN LLTYRGGQAG PRGLALLNGE YLLAAQQGKN 60
YICAWELQRK DQLQQKIMCP GPVTCLTTAP NGLYVLAGIA ESIYLWEVCT GNLLVILSRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAGAGCAA GATGGCGGCG CCCATGGAAG TGGTGGTGTG TACTGACGCC GCGGCACAGC 60
TCTGGAGCTG CGTGGTGTGG GAGCTTCATT CGGGCGCCAA CCTGCTCACC TACCGAGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0217--Developmental protein
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR026987--Wdr18_C_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40
PF14077--WD40_alt

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0007275--P:multicellular organism development

KEGG

mmu:216156

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001040	Aegilops tauschii	33.74	3.00e-29	122.00
IUUC-Aml-001819	Ailuropoda melanoleuca	83.33	0.00e+00	680.00
IUUC-Atr-002688	Amborella trichopoda	35.29	3.00e-40	159.00
IUUC-Apl-004023	Anas platyrhynchos	53.18	4.00e-93	334.00
IUUC-Aca-004879	Anolis carolinensis	70.47	3.00e-52	197.00
IUUC-Aly-006061	Arabidopsis lyrata	31.21	5.00e-35	142.00
IUUC-Ath-007111	Arabidopsis thaliana	31.31	4.00e-33	135.00
IUUC-Ame-010912	Astyanax mexicanus	61.72	1.00e-156	546.00
IUUC-Bgr-012242	Blumeria graminis	25.25	2.00e-12	67.00
IUUC-Bta-013402	Bos taurus	85.88	0.00e+00	720.00
IUUC-Bci-013791	Botrytis cinerea	25.27	1.00e-12	67.40
IUUC-Bdi-015054	Brachypodium distachyon	32.29	1.00e-35	144.00
IUUC-Bol-016342	Brassica oleracea	30.36	4.00e-31	129.00
IUUC-Bra-016967	Brassica rapa	30.69	1.00e-31	130.00
IUUC-Cja-019758	Callithrix jacchus	81.73	0.00e+00	650.00
IUUC-Cfa-020495	Canis familiaris	82.09	1.00e-166	579.00
IUUC-Cpo-021438	Cavia porcellus	86.04	3.00e-168	584.00
IUUC-Csa-023416	Chlorocebus sabaeus	83.10	0.00e+00	699.00
IUUC-Csv-025918	Ciona savignyi	33.26	9.00e-61	227.00
IUUC-Cgl-026618	Colletotrichum gloeosporioides	26.53	9.00e-15	74.70
IUUC-Cne-026843	Cryptococcus neoformans	27.56	8.00e-19	88.60
IUUC-Dre-027560	Danio rerio	59.86	2.00e-152	531.00
IUUC-Dno-029315	Dasypus novemcinctus	81.63	0.00e+00	715.00
IUUC-Dor-030935	Dipodomys ordii	83.41	0.00e+00	720.00
IUUC-Dse-031492	Dothistroma septosporum	23.79	6.00e-17	82.40
IUUC-Dme-032059	Drosophila melanogaster	32.74	2.00e-56	213.00
IUUC-Fca-036068	Felis catus	78.46	0.00e+00	645.00
IUUC-Fal-037467	Ficedula albicollis	68.73	2.00e-149	521.00
IUUC-Fox-037903	Fusarium oxysporum	27.06	5.00e-17	82.00
IUUC-Gmo-039323	Gadus morhua	51.05	2.00e-112	399.00
IUUC-Ggr-040050	Gaeumannomyces graminis	26.55	4.00e-11	62.80
IUUC-Gga-040563	Gallus gallus	69.15	2.00e-142	498.00
IUUC-Gac-042641	Gasterosteus aculeatus	55.79	2.00e-139	489.00
IUUC-Gma-044265	Glycine max	31.60	6.00e-38	151.00
IUUC-Ggo-045137	Gorilla gorilla	83.33	0.00e+00	676.00
IUUC-Hsa-046335	Homo sapiens	83.33	0.00e+00	676.00
IUUC-Hvu-047685	Hordeum vulgare	33.04	1.00e-32	134.00
IUUC-Itr-048032	Ictidomys tridecemlineatus	83.56	0.00e+00	729.00
IUUC-Kpa-049129	Komagataella pastoris	29.80	1.00e-29	124.00
IUUC-Lch-049532	Latimeria chalumnae	64.10	5.00e-168	583.00
IUUC-Lpe-051321	Leersia perrieri	30.28	7.00e-28	118.00
IUUC-Loc-052471	Lepisosteus oculatus	59.82	1.00e-145	509.00
IUUC-Lma-053091	Leptosphaeria maculans	26.54	7.00e-24	105.00
IUUC-Laf-054331	Loxodonta africana	80.32	0.00e+00	657.00
IUUC-Mcc-055803	Macaca mulatta	83.10	0.00e+00	699.00
IUUC-Meu-056090	Macropus eugenii	73.38	0.00e+00	650.00
IUUC-Mor-057160	Magnaporthe oryzae	27.47	8.00e-16	78.60
IUUC-Mtr-058800	Medicago truncatula	32.52	3.00e-38	152.00
IUUC-Mla-058943	Melampsora laricipopulina	37.66	2.00e-25	110.00
IUUC-Mga-059282	Meleagris gallopavo	61.77	1.00e-130	459.00
IUUC-Mvi-060315	Microbotryum violaceum	36.26	8.00e-25	108.00
IUUC-Mmr-061127	Microcebus murinus	86.11	0.00e+00	726.00
IUUC-Mdo-062350	Monodelphis domestica	73.38	0.00e+00	649.00
IUUC-Mac-065554	Musa acuminata	30.00	3.00e-27	116.00
IUUC-Mpu-066711	Mustela putorius furo	83.56	0.00e+00	738.00
IUUC-Mlu-068121	Myotis lucifugus	81.22	1.00e-162	565.00
IUUC-Ncr-068914	Neurospora crassa	27.80	1.00e-14	74.30
IUUC-Nle-069518	Nomascus leucogenys	82.32	0.00e+00	628.00
IUUC-Ont-071435	Oreochromis niloticus	58.93	3.00e-145	508.00
IUUC-Oan-073532	Ornithorhynchus anatinus	68.93	4.00e-40	155.00
IUUC-Oba-075873	Oryza barthii	31.74	2.00e-38	153.00
IUUC-Obr-076097	Oryza brachyantha	26.51	3.00e-25	109.00
IUUC-Ogl-077840	Oryza glaberrima	31.74	1.00e-38	154.00
IUUC-Ogu-077988	Oryza glumaepatula	31.74	2.00e-38	153.00
IUUC-Oin-079237	Oryza indica	33.48	1.00e-25	110.00
IUUC-Olo-080415	Oryza longistaminata	30.55	2.00e-30	128.00
IUUC-Ome-081952	Oryza meridionalis	31.75	2.00e-37	149.00
IUUC-Oni-082300	Oryza nivara	31.74	2.00e-38	153.00
IUUC-Opu-083436	Oryza punctata	34.70	2.00e-24	107.00
IUUC-Oru-085164	Oryza rufipogon	32.05	2.00e-38	153.00
IUUC-Osa-086129	Oryza sativa	31.74	5.00e-39	155.00
IUUC-Ola-086571	Oryzias latipes	55.56	2.00e-134	472.00
IUUC-Oga-088561	Otolemur garnettii	84.95	0.00e+00	717.00
IUUC-Oar-090131	Ovis aries	74.83	5.00e-170	590.00
IUUC-Ptr-091301	Pan troglodytes	66.21	2.00e-148	518.00
IUUC-Pan-092810	Papio anubis	82.87	0.00e+00	697.00
IUUC-Psi-093091	Pelodiscus sinensis	59.78	1.00e-116	412.00
IUUC-Pno-095047	Phaeosphaeria nodorum	23.86	5.00e-17	82.80
IUUC-Ppa-095317	Physcomitrella patens	39.34	4.00e-33	135.00
IUUC-Pfo-096996	Poecilia formosa	58.00	1.00e-137	483.00
IUUC-Pab-097747	Pongo abelii	84.13	0.00e+00	678.00
IUUC-Pop-099609	Populus trichocarpa	33.53	5.00e-42	165.00
IUUC-Pca-100972	Procavia capensis	78.42	2.00e-173	601.00
IUUC-Ppe-101904	Prunus persica	33.85	3.00e-41	162.00
IUUC-Pva-102700	Pteropus vampyrus	70.92	2.00e-149	521.00
IUUC-Pgr-103616	Puccinia graminis	37.01	7.00e-23	102.00
IUUC-Ptt-103954	Puccinia triticina	36.36	1.00e-21	97.80
IUUC-Pte-104120	Pyrenophora teres	26.10	1.00e-24	107.00
IUUC-Pyt-104558	Pyrenophora triticirepentis	25.62	4.00e-25	109.00
IUUC-Rno-104933	Rattus norvegicus	95.82	0.00e+00	817.00
IUUC-Sha-107636	Sarcophilus harrisii	72.92	0.00e+00	647.00
IUUC-Sja-107783	Schizosaccharomyces japonicus	33.02	8.00e-34	138.00
IUUC-Spo-108192	Schizosaccharomyces pombe	27.13	4.00e-24	105.00
IUUC-Ssl-108384	Sclerotinia sclerotiorum	27.86	2.00e-17	83.60
IUUC-Smo-109498	Selaginella moellendorffii	35.99	4.00e-37	149.00
IUUC-Sit-110770	Setaria italica	33.44	8.00e-37	147.00
IUUC-Sly-111453	Solanum lycopersicum	32.87	2.00e-41	163.00
IUUC-Stu-112384	Solanum tuberosum	32.84	5.00e-41	162.00
IUUC-Sbi-113952	Sorghum bicolor	33.13	3.00e-35	142.00
IUUC-Sre-115223	Sporisorium reilianum	26.42	1.00e-23	105.00
IUUC-Ssc-115627	Sus scrofa	85.65	0.00e+00	721.00
IUUC-Tgu-117404	Taeniopygia guttata	68.45	3.00e-141	494.00
IUUC-Tru-117629	Takifugu rubripes	57.03	7.00e-125	440.00
IUUC-Tni-119839	Tetraodon nigroviridis	54.84	2.00e-121	429.00
IUUC-Tca-121766	Theobroma cacao	32.65	4.00e-41	162.00
IUUC-Tae-125634	Triticum aestivum	33.92	6.00e-34	138.00
IUUC-Tur-126673	Triticum urartu	31.70	4.00e-25	108.00
IUUC-Tme-127070	Tuber melanosporum	24.16	3.00e-16	80.10
IUUC-Tbe-127452	Tupaia belangeri	75.54	2.00e-93	335.00
IUUC-Ttr-128735	Tursiops truncatus	82.18	0.00e+00	672.00
IUUC-Uma-129521	Ustilago maydis	30.95	5.00e-22	99.40
IUUC-Vvi-130872	Vitis vinifera	30.49	5.00e-40	158.00
IUUC-Xtr-131838	Xenopus tropicalis	62.94	2.00e-136	478.00
IUUC-Xma-134106	Xiphophorus maculatus	64.63	5.00e-115	407.00
IUUC-Yli-134551	Yarrowia lipolytica	28.70	9.00e-21	94.70
IUUC-Zma-134703	Zea mays	32.62	2.00e-34	140.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence