iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033977

UUCD1 version

UUC-EqC-00731

Ensembl Protein ID

ENSECAP00000016297.1

UniProt Accession

F7BNZ3; F7BNZ3_HORSE

Protein Name

Uncharacterized protein

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018384.1	ENSECAT00000019879.1	ENSECAP00000016297.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-42	141.2	235	275
UBD/Beta-Prp	1.90e-54	185.0	189	394

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 235  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 275
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 189  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 276
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 277  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 365
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 366  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           ***************************** PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRSVFKKS QQFSYCSTCA EIVNTENLGP NPAFASFWEE 60
AEALTRKLEE IRVAYGDASL HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT AGTTAATGTA TTTGGCTCTT GTGACAAATG TTTCAAACAA 60
AGGGCTCTGA GATCAGTTTT CAAGAAATCT CAACAGTTCA GCTACTGTTC AACATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	91.39	0.00e+00	750.00
IUUC-Apl-003399	Anas platyrhynchos	98.72	0.00e+00	649.00
IUUC-Aca-004861	Anolis carolinensis	88.61	0.00e+00	737.00
IUUC-Ame-011851	Astyanax mexicanus	89.08	0.00e+00	658.00
IUUC-Bta-012438	Bos taurus	94.00	0.00e+00	684.00
IUUC-Cel-018408	Caenorhabditis elegans	64.88	6.00e-135	473.00
IUUC-Cja-019086	Callithrix jacchus	94.15	0.00e+00	767.00
IUUC-Cfa-021255	Canis familiaris	93.38	0.00e+00	737.00
IUUC-Cpo-021398	Cavia porcellus	91.41	0.00e+00	749.00
IUUC-Csa-023776	Chlorocebus sabaeus	94.59	0.00e+00	688.00
IUUC-Cin-025305	Ciona intestinalis	57.94	1.00e-127	449.00
IUUC-Csv-026058	Ciona savignyi	56.27	2.00e-124	438.00
IUUC-Dre-028432	Danio rerio	80.76	0.00e+00	657.00
IUUC-Dno-029958	Dasypus novemcinctus	82.13	3.00e-137	481.00
IUUC-Dor-031013	Dipodomys ordii	99.22	1.00e-152	532.00
IUUC-Dme-031889	Drosophila melanogaster	66.96	6.00e-144	503.00
IUUC-Eeu-035079	Erinaceus europaeus	92.35	0.00e+00	748.00
IUUC-Fca-035693	Felis catus	91.44	0.00e+00	741.00
IUUC-Fal-037345	Ficedula albicollis	93.16	0.00e+00	683.00
IUUC-Gmo-039222	Gadus morhua	92.28	0.00e+00	639.00
IUUC-Gga-040320	Gallus gallus	93.45	0.00e+00	684.00
IUUC-Gac-042644	Gasterosteus aculeatus	88.03	0.00e+00	658.00
IUUC-Ggo-044489	Gorilla gorilla	91.67	0.00e+00	746.00
IUUC-Hsa-046434	Homo sapiens	94.18	0.00e+00	771.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	94.27	6.00e-176	609.00
IUUC-Loc-052790	Lepisosteus oculatus	86.22	0.00e+00	693.00
IUUC-Laf-054255	Loxodonta africana	92.11	0.00e+00	751.00
IUUC-Mcc-055610	Macaca mulatta	93.89	0.00e+00	764.00
IUUC-Meu-056819	Macropus eugenii	85.97	0.00e+00	686.00
IUUC-Mga-059740	Meleagris gallopavo	84.52	0.00e+00	706.00
IUUC-Mmr-061221	Microcebus murinus	93.67	0.00e+00	768.00
IUUC-Mdo-062619	Monodelphis domestica	93.43	0.00e+00	682.00
IUUC-Mmu-064266	Mus musculus	93.42	0.00e+00	768.00
IUUC-Mpu-065766	Mustela putorius furo	99.34	0.00e+00	626.00
IUUC-Mlu-067221	Myotis lucifugus	89.67	0.00e+00	731.00
IUUC-Nle-069515	Nomascus leucogenys	99.68	0.00e+00	659.00
IUUC-Opr-070195	Ochotona princeps	85.24	0.00e+00	677.00
IUUC-Ont-071535	Oreochromis niloticus	75.19	6.00e-168	583.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	4.00e-107	379.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.67	0.00e+00	627.00
IUUC-Ola-086578	Oryzias latipes	94.34	0.00e+00	639.00
IUUC-Oga-089090	Otolemur garnettii	92.95	0.00e+00	760.00
IUUC-Oar-090017	Ovis aries	89.85	0.00e+00	726.00
IUUC-Ptr-091280	Pan troglodytes	89.87	0.00e+00	721.00
IUUC-Pan-092198	Papio anubis	99.68	0.00e+00	659.00
IUUC-Psi-093030	Pelodiscus sinensis	84.58	0.00e+00	709.00
IUUC-Pma-094140	Petromyzon marinus	76.06	2.00e-94	338.00
IUUC-Pfo-097182	Poecilia formosa	92.90	0.00e+00	642.00
IUUC-Pab-098157	Pongo abelii	94.59	0.00e+00	689.00
IUUC-Pca-100988	Procavia capensis	71.90	4.00e-156	543.00
IUUC-Pva-102232	Pteropus vampyrus	81.03	5.00e-163	566.00
IUUC-Rno-105526	Rattus norvegicus	90.37	0.00e+00	648.00
IUUC-Sha-106754	Sarcophilus harrisii	91.65	0.00e+00	728.00
IUUC-Ssc-115390	Sus scrofa	93.18	0.00e+00	763.00
IUUC-Tgu-117377	Taeniopygia guttata	86.77	0.00e+00	694.00
IUUC-Tru-117938	Takifugu rubripes	94.04	0.00e+00	640.00
IUUC-Tsy-119392	Tarsius syrichta	81.01	0.00e+00	628.00
IUUC-Tni-119834	Tetraodon nigroviridis	69.62	2.00e-160	558.00
IUUC-Tbe-127469	Tupaia belangeri	90.96	0.00e+00	690.00
IUUC-Ttr-128252	Tursiops truncatus	89.90	0.00e+00	724.00
IUUC-Vpa-130173	Vicugna pacos	80.65	7.00e-157	546.00
IUUC-Xtr-131803	Xenopus tropicalis	87.34	0.00e+00	706.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence