iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028193

UUCD1 version

UUC-DaR-01281

Ensembl Protein ID

ENSDARP00000013849.8

UniProt Accession

Q7T1K2; Q7T1K2_DANRE

Genbank Protein ID

AAH65969.1; CAD89005.1

Protein Name

TRAF4 protein; Tnf receptor-associated factor 4a

Genbank Nucleotide ID

CR848661; AJ556548

Gene Name

traf4a; traf4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000003963.8	ENSDART00000016024.8	ENSDARP00000013849.8

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.30e-06	28.5	14	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
             f Cp+  + Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l + i
   Q: 14   RRFQCPLCSKAMREPVQVStCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQI 76
           67***************999*****************99*****************9998877 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRFQCPL CSKAMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEQQILALP IRCIHSEEGC RWTGQMKQLQ SHFSTCAFNV IPCPNRCSVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTGTGGA TGTTTCTCGT CCTCTCGGTT CATCAGCGAG CTCTAGCCTG CATTGACAGC 60
CTCGTCGCCG GGTTTAAGCT GTCATCCTGA CCGAGCCGTG TTGCTCGAAA AGAGGAAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0675--Receptor
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00917--MATH
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0042981--P:regulation of apoptotic process

KEGG

dre:404045

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000744	Aegilops tauschii	26.45	2.00e-08	55.10
IUUC-Aml-001287	Ailuropoda melanoleuca	75.91	0.00e+00	754.00
IUUC-Ame-011530	Astyanax mexicanus	96.17	0.00e+00	919.00
IUUC-Bta-013582	Bos taurus	76.17	0.00e+00	763.00
IUUC-Bdi-014617	Brachypodium distachyon	25.90	2.00e-08	55.80
IUUC-Bol-016391	Brassica oleracea	31.01	3.00e-07	50.40
IUUC-Bra-017948	Brassica rapa	33.33	5.00e-06	46.60
IUUC-Cfa-020133	Canis familiaris	73.19	0.00e+00	712.00
IUUC-Cpo-022021	Cavia porcellus	76.38	0.00e+00	769.00
IUUC-Csa-023199	Chlorocebus sabaeus	76.60	0.00e+00	770.00
IUUC-Dno-028917	Dasypus novemcinctus	76.81	0.00e+00	773.00
IUUC-Ete-032433	Echinops telfairi	76.17	0.00e+00	764.00
IUUC-Fca-036155	Felis catus	77.23	0.00e+00	774.00
IUUC-Gmo-038860	Gadus morhua	95.53	0.00e+00	915.00
IUUC-Gga-041052	Gallus gallus	82.34	0.00e+00	851.00
IUUC-Gac-041489	Gasterosteus aculeatus	94.89	0.00e+00	910.00
IUUC-Gma-043859	Glycine max	32.00	1.00e-07	53.10
IUUC-Ggo-044996	Gorilla gorilla	76.60	0.00e+00	769.00
IUUC-Hsa-046252	Homo sapiens	76.81	0.00e+00	772.00
IUUC-Hvu-047095	Hordeum vulgare	27.27	2.00e-08	55.50
IUUC-Itr-048232	Ictidomys tridecemlineatus	77.02	0.00e+00	774.00
IUUC-Kpa-049340	Komagataella pastoris	27.80	4.00e-16	79.70
IUUC-Lpe-050771	Leersia perrieri	28.93	1.00e-07	52.80
IUUC-Loc-052312	Lepisosteus oculatus	91.93	0.00e+00	888.00
IUUC-Laf-054376	Loxodonta africana	76.60	0.00e+00	769.00
IUUC-Mcc-055684	Macaca mulatta	76.60	0.00e+00	770.00
IUUC-Mtr-057807	Medicago truncatula	28.93	3.00e-07	51.60
IUUC-Mmr-061198	Microcebus murinus	77.02	0.00e+00	774.00
IUUC-Mdo-062585	Monodelphis domestica	76.38	0.00e+00	768.00
IUUC-Mmu-064303	Mus musculus	77.02	0.00e+00	773.00
IUUC-Mac-064547	Musa acuminata	28.93	2.00e-07	52.00
IUUC-Mpu-066854	Mustela putorius furo	76.81	0.00e+00	770.00
IUUC-Nle-070098	Nomascus leucogenys	75.74	0.00e+00	761.00
IUUC-Ont-071518	Oreochromis niloticus	95.74	0.00e+00	917.00
IUUC-Ocu-073841	Oryctolagus cuniculus	76.38	0.00e+00	768.00
IUUC-Oba-075596	Oryza barthii	28.93	2.00e-07	52.40
IUUC-Obr-076500	Oryza brachyantha	38.46	4.00e-09	55.80
IUUC-Ogl-077360	Oryza glaberrima	28.93	7.00e-08	52.80
IUUC-Ogu-078462	Oryza glumaepatula	28.93	2.00e-07	52.40
IUUC-Oin-079887	Oryza indica	28.93	2.00e-07	52.40
IUUC-Ome-081269	Oryza meridionalis	35.90	2.00e-08	53.10
IUUC-Oni-083040	Oryza nivara	35.90	4.00e-08	52.00
IUUC-Oru-084831	Oryza rufipogon	28.93	2.00e-07	52.00
IUUC-Osa-085740	Oryza sativa	34.62	1.00e-07	50.80
IUUC-Ola-086674	Oryzias latipes	94.89	0.00e+00	910.00
IUUC-Olu-087748	Ostreococcus lucimarinus	29.76	1.00e-05	44.30
IUUC-Oga-088510	Otolemur garnettii	76.38	0.00e+00	767.00
IUUC-Oar-089225	Ovis aries	73.62	0.00e+00	728.00
IUUC-Pan-092725	Papio anubis	76.60	0.00e+00	770.00
IUUC-Pfo-096341	Poecilia formosa	95.11	0.00e+00	914.00
IUUC-Pop-099390	Populus trichocarpa	30.30	1.00e-07	52.80
IUUC-Ppe-101708	Prunus persica	30.30	6.00e-09	57.40
IUUC-Pva-103131	Pteropus vampyrus	72.52	2.00e-111	396.00
IUUC-Rno-105996	Rattus norvegicus	77.23	0.00e+00	774.00
IUUC-Sly-111800	Solanum lycopersicum	33.61	3.00e-09	58.50
IUUC-Sbi-114841	Sorghum bicolor	28.10	2.00e-08	55.50
IUUC-Tru-117602	Takifugu rubripes	94.26	0.00e+00	905.00
IUUC-Tca-121454	Theobroma cacao	32.00	8.00e-08	53.50
IUUC-Tae-123531	Triticum aestivum	26.45	3.00e-08	54.70
IUUC-Tur-126325	Triticum urartu	27.27	1.00e-08	55.80
IUUC-Ttr-128370	Tursiops truncatus	77.81	2.00e-175	608.00
IUUC-Vvi-131070	Vitis vinifera	26.98	1.00e-08	54.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence