iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000021407.3	ENSMMUT00000030133.3	ENSMMUP00000028200.3
ENSMMUG00000021407.3	ENSMMUT00000023821.3	ENSMMUP00000022296.3
ENSMMUG00000021407.3	ENSMMUT00000030134.3	ENSMMUP00000028201.3
ENSMMUG00000021407.3	ENSMMUT00000073207.1	ENSMMUP00000044534.1
ENSMMUG00000021407.3	ENSMMUT00000056564.1	ENSMMUP00000055558.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.10e-06	28.0	18	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           ********99888888**********999.....89*******6 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEVQVLGLP IRCIHSEEGC RWNGPLRHLQ GHLNTCSFNV VPCPNRCPMK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGAGGCGCG GGCTGTGGGG CCGCCGCGTG CCTGGCCCCG CTCGCCCGTG CCGGCCGCTC 60
GCCCGCCATG CCTGGTTTCG ACTACAAGTT CCTGGAGAAG CCCAAGCGAC GGCTGCTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0675--Receptor
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

KEGG

mcc:716364

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	40.51	3.00e-08	53.10
IUUC-Aml-001287	Ailuropoda melanoleuca	96.38	0.00e+00	899.00
IUUC-Ame-011530	Astyanax mexicanus	77.45	0.00e+00	774.00
IUUC-Bta-013582	Bos taurus	98.72	0.00e+00	924.00
IUUC-Cja-019883	Callithrix jacchus	94.79	1.00e-51	194.00
IUUC-Cfa-020133	Canis familiaris	91.70	0.00e+00	850.00
IUUC-Cpo-022021	Cavia porcellus	98.72	0.00e+00	928.00
IUUC-Csa-023199	Chlorocebus sabaeus	100.00	0.00e+00	937.00
IUUC-Dre-028193	Danio rerio	76.60	0.00e+00	769.00
IUUC-Dno-028917	Dasypus novemcinctus	98.72	0.00e+00	927.00
IUUC-Ete-032433	Echinops telfairi	97.45	0.00e+00	915.00
IUUC-Fca-036155	Felis catus	97.87	0.00e+00	922.00
IUUC-Gmo-038860	Gadus morhua	77.45	0.00e+00	772.00
IUUC-Gga-041052	Gallus gallus	80.85	0.00e+00	827.00
IUUC-Gac-041489	Gasterosteus aculeatus	77.23	0.00e+00	770.00
IUUC-Gma-042951	Glycine max	26.77	8.00e-08	51.60
IUUC-Ggo-044996	Gorilla gorilla	98.94	0.00e+00	928.00
IUUC-Hsa-046252	Homo sapiens	99.15	0.00e+00	931.00
IUUC-Itr-048232	Ictidomys tridecemlineatus	99.15	0.00e+00	930.00
IUUC-Kpa-049340	Komagataella pastoris	26.46	1.00e-15	78.20
IUUC-Lpe-051100	Leersia perrieri	38.57	1.00e-07	50.80
IUUC-Loc-052312	Lepisosteus oculatus	77.07	0.00e+00	767.00
IUUC-Laf-054376	Loxodonta africana	98.72	0.00e+00	926.00
IUUC-Mmr-061198	Microcebus murinus	99.15	0.00e+00	929.00
IUUC-Mdo-062585	Monodelphis domestica	87.45	0.00e+00	833.00
IUUC-Mmu-064303	Mus musculus	97.23	0.00e+00	917.00
IUUC-Mac-064529	Musa acuminata	30.40	2.00e-10	60.10
IUUC-Mpu-066854	Mustela putorius furo	97.45	0.00e+00	918.00
IUUC-Nle-070098	Nomascus leucogenys	97.87	0.00e+00	919.00
IUUC-Ont-071518	Oreochromis niloticus	77.40	0.00e+00	771.00
IUUC-Ocu-073841	Oryctolagus cuniculus	98.94	0.00e+00	929.00
IUUC-Ola-086674	Oryzias latipes	77.19	0.00e+00	769.00
IUUC-Oga-088510	Otolemur garnettii	98.72	0.00e+00	927.00
IUUC-Oar-089225	Ovis aries	94.89	0.00e+00	881.00
IUUC-Pan-092725	Papio anubis	100.00	0.00e+00	937.00
IUUC-Pfo-096341	Poecilia formosa	77.19	0.00e+00	772.00
IUUC-Pva-103131	Pteropus vampyrus	99.24	1.00e-143	502.00
IUUC-Rno-105996	Rattus norvegicus	97.45	0.00e+00	918.00
IUUC-Sly-111800	Solanum lycopersicum	30.00	6.00e-06	47.40
IUUC-Tru-117602	Takifugu rubripes	77.45	0.00e+00	775.00
IUUC-Tur-126067	Triticum urartu	40.51	2.00e-08	53.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence