iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000003634.3	ENSCPOT00000003678.2	ENSCPOP00000003282.2
ENSCPOG00000003634.3	ENSCPOT00000014808.2	ENSCPOP00000013212.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.40e-56	188.5	5	139
UBD/UBC-like/UBD_UBC	1.50e-81	271.3	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++ el++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  
   Q: 5    RVQPELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR-- 90
           8999********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal+v++vllsi+sll++pnp++pl  e+a+++k++re+y++ ++
   Q: 91   SQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAQ 139
           *********************************************9876 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           r++ el dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqw
   Q: 5    RVQPELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQW 93
           8999************************************************************************************* PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv+eia+ yk+d+eky+r a+ewt
   Q: 94   SPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAQEWT 142
           ************************************************8 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

QRSHRVQPEL TDLQRDPPAQ CSAGPVGDDL FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGAAGCC ACAGAGTCCA ACCACTTTTT TTTTTTCAGT ACTAGGGATC AAACTCACAA 60
GTCACACTTG GCAGGCAGGC GCTTATGCCA CCGAACTAAA TCCCCAGCCC AAGCCCAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006221	Arabidopsis lyrata	80.69	6.00e-70	255.00
IUUC-Ath-007700	Arabidopsis thaliana	80.69	7.00e-69	252.00
IUUC-Afl-008709	Aspergillus flavus	81.16	2.00e-68	253.00
IUUC-Ang-009725	Aspergillus niger	83.20	2.00e-61	227.00
IUUC-Ame-011566	Astyanax mexicanus	93.71	3.00e-79	286.00
IUUC-Bol-015722	Brassica oleracea	80.00	1.00e-69	255.00
IUUC-Cja-019014	Callithrix jacchus	97.18	7.00e-81	291.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	77.93	6.00e-68	249.00
IUUC-Csa-023377	Chlorocebus sabaeus	96.50	2.00e-80	290.00
IUUC-Dre-028686	Danio rerio	97.20	6.00e-82	295.00
IUUC-Dor-030323	Dipodomys ordii	97.20	6.00e-82	295.00
IUUC-Eca-033231	Equus caballus	99.28	1.00e-80	290.00
IUUC-Gmo-038775	Gadus morhua	89.51	1.00e-76	278.00
IUUC-Gac-042534	Gasterosteus aculeatus	90.91	5.00e-76	276.00
IUUC-Ggo-045361	Gorilla gorilla	97.90	3.00e-82	296.00
IUUC-Hsa-045934	Homo sapiens	97.90	3.00e-82	296.00
IUUC-Loc-052838	Lepisosteus oculatus	97.90	3.00e-82	296.00
IUUC-Mcc-055421	Macaca mulatta	97.90	3.00e-82	296.00
IUUC-Mmr-061446	Microcebus murinus	96.40	7.00e-79	285.00
IUUC-Mdo-062413	Monodelphis domestica	98.56	4.00e-80	289.00
IUUC-Mlu-067573	Myotis lucifugus	90.65	4.00e-74	269.00
IUUC-Nle-069715	Nomascus leucogenys	97.90	3.00e-82	296.00
IUUC-Ont-072562	Oreochromis niloticus	94.41	4.00e-80	289.00
IUUC-Oan-073026	Ornithorhynchus anatinus	99.28	1.00e-80	291.00
IUUC-Ocu-073914	Oryctolagus cuniculus	97.12	3.00e-79	286.00
IUUC-Oru-085167	Oryza rufipogon	79.31	1.00e-69	256.00
IUUC-Ola-087515	Oryzias latipes	95.10	2.00e-80	290.00
IUUC-Olu-087615	Ostreococcus lucimarinus	75.86	1.00e-64	238.00
IUUC-Pan-092614	Papio anubis	96.53	5.00e-81	292.00
IUUC-Pfo-096867	Poecilia formosa	95.10	2.00e-80	290.00
IUUC-Pab-098760	Pongo abelii	97.20	1.00e-81	295.00
IUUC-Ptt-103723	Puccinia triticina	76.98	9.00e-60	222.00
IUUC-Sha-106489	Sarcophilus harrisii	90.65	2.00e-74	270.00
IUUC-Sit-109936	Setaria italica	79.31	3.00e-69	254.00
IUUC-Sly-110857	Solanum lycopersicum	79.31	7.00e-69	252.00
IUUC-Stu-112436	Solanum tuberosum	79.31	1.00e-69	254.00
IUUC-Ssc-115391	Sus scrofa	97.90	3.00e-82	296.00
IUUC-Tsy-118832	Tarsius syrichta	95.80	1.00e-79	287.00
IUUC-Tca-121542	Theobroma cacao	79.31	5.00e-70	256.00
IUUC-Tbe-128122	Tupaia belangeri	96.77	7.00e-61	224.00
IUUC-Xtr-132238	Xenopus tropicalis	95.80	5.00e-81	292.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence