iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098449

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-like modifier-activating enzyme 5

Genbank Nucleotide ID

ABGA01305521

Gene Name

UBA5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000014108.2	ENSPPYT00000016407.2	ENSPPYP00000015785.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.40e-52	177.5	53	231

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirl..wGeeaq.eklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnp 86
           Y+R+++l  +G++++ ek++++ v +vG+gg+G+ ++++L+ +G+g++ ++D+d+ve++n+nr F f+++++g sK+++a+++l+++np
   Q: 53   YSRLMALkrMGIVSDyEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSKVQAAEHTLRNINP 140
           9****************************************************************.*********************** PP
   S: 87   dvnveaheesiteleeeivFfkkf...........dvVvlaldnrearrkvnrlclnarvpliesgtlG..llGqvrviikgltecysc 162
           dv +e+h+++it+ e+ ++F++++           d+V++++dn+ear+++n++c ++    +esg+    + G+++ ii+g  +c  c
   Q: 141  DVLFEVHNYNITTVENFQHFMDRIsnggleegkpvDLVLSCVDNFEARMTINTACNELGQTWMESGVSEnaVSGHIQLIIPGESACFAC 229
           ******************************************************************9863367*************999 PP
   S: 163  sd 164
            +
   Q: 230  AP 231
           76 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAVSVERLQQ RVQELERELA QERSLQVPRS GDGGGGRVRI EKMSSEVVDS NPYSRLMALK 60
RMGIVSDYEK IRTFAVAIVG VGGVGSVTAE MLTRCGIGKL LLFDYDKVEL ANMNRLFFQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGTGT CTGTGGAGCG GCTGCAGCAG CGGGTCCAGG AGCTGGAGCG GGAACTTGCC 60
CAGGAGAGGA GTCTGCAGGT CCCGAGGAGC GGCGACGGAG GGGGCGGCCG GGTCCGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029752--D-isomer_DH_CS1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

PROSITE

PS00065--D_2_HYDROXYACID_DH_1

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0071566--F:UFM1 activating enzyme activity
GO:1990592--P:protein K69-linked ufmylation
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:0034976--P:response to endoplasmic reticulum stress

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001324	Ailuropoda melanoleuca	95.61	0.00e+00	668.00
IUUC-Atr-002660	Amborella trichopoda	58.40	7.00e-114	403.00
IUUC-Apl-003722	Anas platyrhynchos	88.32	2.00e-162	564.00
IUUC-Aca-004584	Anolis carolinensis	88.32	5.00e-171	593.00
IUUC-Aly-005881	Arabidopsis lyrata	57.29	4.00e-113	401.00
IUUC-Ath-007286	Arabidopsis thaliana	60.11	4.00e-117	414.00
IUUC-Ame-011679	Astyanax mexicanus	82.68	8.00e-142	496.00
IUUC-Bta-012517	Bos taurus	95.89	0.00e+00	682.00
IUUC-Bdi-014894	Brachypodium distachyon	60.87	3.00e-113	401.00
IUUC-Bol-016054	Brassica oleracea	62.50	2.00e-116	412.00
IUUC-Bra-016708	Brassica rapa	61.62	1.00e-119	423.00
IUUC-Cel-018424	Caenorhabditis elegans	62.87	3.00e-120	425.00
IUUC-Cja-019825	Callithrix jacchus	95.94	2.00e-147	514.00
IUUC-Cfa-021160	Canis familiaris	95.79	0.00e+00	696.00
IUUC-Cpo-022255	Cavia porcellus	90.18	0.00e+00	669.00
IUUC-Csa-023827	Chlorocebus sabaeus	97.28	0.00e+00	726.00
IUUC-Cho-025078	Choloepus hoffmanni	90.76	0.00e+00	641.00
IUUC-Cin-025217	Ciona intestinalis	71.28	1.00e-153	535.00
IUUC-Dre-027578	Danio rerio	81.82	2.00e-169	588.00
IUUC-Dno-029330	Dasypus novemcinctus	90.95	0.00e+00	680.00
IUUC-Dor-030425	Dipodomys ordii	59.71	1.00e-106	379.00
IUUC-Dme-031645	Drosophila melanogaster	62.32	2.00e-135	475.00
IUUC-Ete-032912	Echinops telfairi	94.74	1.00e-59	223.00
IUUC-Eca-033247	Equus caballus	96.99	0.00e+00	670.00
IUUC-Eeu-034472	Erinaceus europaeus	96.00	0.00e+00	635.00
IUUC-Fca-035684	Felis catus	97.28	0.00e+00	670.00
IUUC-Fal-037654	Ficedula albicollis	85.87	1.00e-166	578.00
IUUC-Gmo-039449	Gadus morhua	67.76	8.00e-128	449.00
IUUC-Gga-041051	Gallus gallus	87.40	2.00e-171	594.00
IUUC-Gac-042325	Gasterosteus aculeatus	76.18	1.00e-171	595.00
IUUC-Gma-043136	Glycine max	59.48	6.00e-122	430.00
IUUC-Ggo-044414	Gorilla gorilla	98.76	0.00e+00	742.00
IUUC-Hsa-046777	Homo sapiens	98.76	0.00e+00	748.00
IUUC-Hvu-047549	Hordeum vulgare	62.36	8.00e-96	343.00
IUUC-Itr-048175	Ictidomys tridecemlineatus	95.72	0.00e+00	673.00
IUUC-Lch-050142	Latimeria chalumnae	81.23	0.00e+00	630.00
IUUC-Lpe-050769	Leersia perrieri	65.96	2.00e-101	362.00
IUUC-Loc-052405	Lepisosteus oculatus	83.19	6.00e-162	563.00
IUUC-Laf-054152	Loxodonta africana	94.80	0.00e+00	691.00
IUUC-Mcc-055618	Macaca mulatta	99.14	0.00e+00	644.00
IUUC-Meu-056486	Macropus eugenii	91.74	7.00e-172	596.00
IUUC-Mtr-057871	Medicago truncatula	59.52	6.00e-120	424.00
IUUC-Mga-059284	Meleagris gallopavo	87.40	9.00e-171	592.00
IUUC-Mmr-061242	Microcebus murinus	94.97	0.00e+00	701.00
IUUC-Mdo-063034	Monodelphis domestica	91.03	0.00e+00	638.00
IUUC-Mmu-064322	Mus musculus	88.53	0.00e+00	644.00
IUUC-Mac-065128	Musa acuminata	60.59	6.00e-69	259.00
IUUC-Mpu-066438	Mustela putorius furo	96.99	0.00e+00	665.00
IUUC-Mlu-067578	Myotis lucifugus	96.71	0.00e+00	662.00
IUUC-Nle-069542	Nomascus leucogenys	99.21	0.00e+00	705.00
IUUC-Opr-070710	Ochotona princeps	87.87	0.00e+00	629.00
IUUC-Ont-072067	Oreochromis niloticus	86.88	4.00e-166	577.00
IUUC-Oan-073593	Ornithorhynchus anatinus	88.35	4.00e-176	610.00
IUUC-Ocu-073964	Oryctolagus cuniculus	91.83	0.00e+00	676.00
IUUC-Oba-075476	Oryza barthii	55.73	1.00e-114	406.00
IUUC-Obr-076517	Oryza brachyantha	59.28	2.00e-113	402.00
IUUC-Ogu-078664	Oryza glumaepatula	55.98	4.00e-115	407.00
IUUC-Olo-081012	Oryza longistaminata	55.73	2.00e-114	405.00
IUUC-Ome-081129	Oryza meridionalis	58.79	2.00e-114	405.00
IUUC-Oni-082265	Oryza nivara	56.44	1.00e-113	402.00
IUUC-Opu-084121	Oryza punctata	59.44	3.00e-114	405.00
IUUC-Oru-084451	Oryza rufipogon	57.14	2.00e-98	352.00
IUUC-Osa-086132	Oryza sativa	55.73	1.00e-114	406.00
IUUC-Ola-086842	Oryzias latipes	81.30	4.00e-160	557.00
IUUC-Oga-088160	Otolemur garnettii	95.45	0.00e+00	657.00
IUUC-Oar-089362	Ovis aries	96.44	0.00e+00	692.00
IUUC-Ptr-091256	Pan troglodytes	98.76	0.00e+00	749.00
IUUC-Pan-092913	Papio anubis	97.69	0.00e+00	683.00
IUUC-Psi-093740	Pelodiscus sinensis	89.46	3.00e-164	570.00
IUUC-Pma-094485	Petromyzon marinus	84.30	1.00e-107	382.00
IUUC-Ppa-095673	Physcomitrella patens	58.29	6.00e-114	404.00
IUUC-Pfo-096196	Poecilia formosa	81.91	2.00e-164	571.00
IUUC-Pop-099049	Populus trichocarpa	59.89	5.00e-115	407.00
IUUC-Pca-100917	Procavia capensis	95.82	4.00e-126	444.00
IUUC-Ppe-101797	Prunus persica	55.80	2.00e-118	419.00
IUUC-Pva-102852	Pteropus vampyrus	97.01	0.00e+00	674.00
IUUC-Rno-105213	Rattus norvegicus	88.56	0.00e+00	647.00
IUUC-Sha-107569	Sarcophilus harrisii	85.09	0.00e+00	655.00
IUUC-Smo-109146	Selaginella moellendorffii	63.07	2.00e-115	408.00
IUUC-Sit-109794	Setaria italica	62.46	1.00e-115	409.00
IUUC-Sly-111622	Solanum lycopersicum	61.90	1.00e-117	416.00
IUUC-Stu-112522	Solanum tuberosum	65.12	1.00e-117	416.00
IUUC-Sar-113045	Sorex araneus	82.79	3.00e-174	603.00
IUUC-Sbi-113861	Sorghum bicolor	60.40	4.00e-115	408.00
IUUC-Ssc-115290	Sus scrofa	96.72	6.00e-164	569.00
IUUC-Tgu-117125	Taeniopygia guttata	85.79	1.00e-168	585.00
IUUC-Tru-118041	Takifugu rubripes	83.70	2.00e-171	595.00
IUUC-Tsy-119300	Tarsius syrichta	86.29	4.00e-154	536.00
IUUC-Tni-120310	Tetraodon nigroviridis	83.15	5.00e-161	560.00
IUUC-Tca-121405	Theobroma cacao	57.76	2.00e-116	412.00
IUUC-Tae-123656	Triticum aestivum	57.33	3.00e-114	404.00
IUUC-Tur-125985	Triticum urartu	60.17	4.00e-114	404.00
IUUC-Tbe-127478	Tupaia belangeri	75.00	3.00e-156	544.00
IUUC-Ttr-128169	Tursiops truncatus	74.75	2.00e-148	518.00
IUUC-Vpa-130508	Vicugna pacos	89.71	3.00e-162	564.00
IUUC-Vvi-131252	Vitis vinifera	58.55	8.00e-117	413.00
IUUC-Xtr-132776	Xenopus tropicalis	83.29	4.00e-172	597.00
IUUC-Xma-133110	Xiphophorus maculatus	82.18	3.00e-167	581.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence