iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000015645.2	ENSLACT00000017895.1	ENSLACP00000017765.1
ENSLACG00000015645.2	ENSLACT00000025798.1	ENSLACP00000022036.1
ENSLACG00000015645.2	ENSLACT00000017896.1	ENSLACP00000017766.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.00e-14	53.0	80	137

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++++++W+++  ++++ +G +P+n+++ ++
   Q: 80   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNHNGEWCEA--QTKNGQGWVPSNYITPVN 137
           68899************************.***********..79999**********997 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MGQQPGKVLG DQRRPSLPAL HFIKGGKKDS SRHVPPCNVF VEHEALQRPI VSDFEPQGLS 60
EAARWNSKEN LLAGPSENDP NLFVALYDFV ASGDNTLSIT KGEKLRVLGY NHNGEWCEAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCAGC AGCCAGGAAA AGTTCTCGGG GACCAGAGGA GGCCAAGTCT GCCTGCCCTA 60
CACTTTATCA AAGGAGGGAA AAAAGATTCA TCCCGGCATG TACCTCCCTG CAATGTCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

KEGG

lcm:102355014

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001550	Ailuropoda melanoleuca	76.63	0.00e+00	1531.00
IUUC-Apl-003452	Anas platyrhynchos	78.33	0.00e+00	1575.00
IUUC-Aca-005312	Anolis carolinensis	77.96	0.00e+00	1221.00
IUUC-Ame-011903	Astyanax mexicanus	72.24	0.00e+00	1123.00
IUUC-Bta-012351	Bos taurus	74.73	0.00e+00	1494.00
IUUC-Cja-019491	Callithrix jacchus	78.00	0.00e+00	1599.00
IUUC-Cfa-021256	Canis familiaris	76.93	0.00e+00	1580.00
IUUC-Cpo-022046	Cavia porcellus	79.13	0.00e+00	1348.00
IUUC-Csa-023046	Chlorocebus sabaeus	77.50	0.00e+00	1550.00
IUUC-Dre-028190	Danio rerio	67.63	0.00e+00	1274.00
IUUC-Dno-029853	Dasypus novemcinctus	76.57	0.00e+00	1587.00
IUUC-Dor-030635	Dipodomys ordii	69.97	0.00e+00	1410.00
IUUC-Dme-032098	Drosophila melanogaster	75.53	0.00e+00	779.00
IUUC-Eca-033720	Equus caballus	77.10	0.00e+00	1528.00
IUUC-Eeu-035173	Erinaceus europaeus	76.87	0.00e+00	1268.00
IUUC-Fca-035967	Felis catus	76.91	0.00e+00	1563.00
IUUC-Fal-036723	Ficedula albicollis	78.69	0.00e+00	1587.00
IUUC-Gmo-039550	Gadus morhua	77.42	0.00e+00	1154.00
IUUC-Gga-040481	Gallus gallus	78.23	0.00e+00	1552.00
IUUC-Gac-041643	Gasterosteus aculeatus	66.84	0.00e+00	1300.00
IUUC-Ggo-045299	Gorilla gorilla	77.22	0.00e+00	1617.00
IUUC-Hsa-047033	Homo sapiens	97.30	5.00e-41	158.00
IUUC-Itr-047935	Ictidomys tridecemlineatus	75.49	0.00e+00	1492.00
IUUC-Loc-052430	Lepisosteus oculatus	84.59	0.00e+00	1019.00
IUUC-Laf-053609	Loxodonta africana	77.41	0.00e+00	1569.00
IUUC-Mcc-055654	Macaca mulatta	78.03	0.00e+00	1638.00
IUUC-Meu-056488	Macropus eugenii	71.02	0.00e+00	1416.00
IUUC-Mga-059270	Meleagris gallopavo	78.74	0.00e+00	1603.00
IUUC-Mmr-060593	Microcebus murinus	74.33	0.00e+00	1515.00
IUUC-Mdo-062227	Monodelphis domestica	85.00	0.00e+00	1255.00
IUUC-Mmu-064002	Mus musculus	75.24	0.00e+00	1542.00
IUUC-Mpu-066197	Mustela putorius furo	76.20	0.00e+00	1557.00
IUUC-Mlu-067255	Myotis lucifugus	77.61	0.00e+00	1499.00
IUUC-Nle-069977	Nomascus leucogenys	69.06	0.00e+00	1404.00
IUUC-Opr-070327	Ochotona princeps	71.05	0.00e+00	1352.00
IUUC-Ont-072307	Oreochromis niloticus	67.50	0.00e+00	1279.00
IUUC-Oan-073100	Ornithorhynchus anatinus	76.21	0.00e+00	1530.00
IUUC-Ocu-074892	Oryctolagus cuniculus	79.31	0.00e+00	1166.00
IUUC-Ola-087389	Oryzias latipes	68.98	0.00e+00	1105.00
IUUC-Oga-088145	Otolemur garnettii	77.93	0.00e+00	1517.00
IUUC-Oar-090432	Ovis aries	83.80	0.00e+00	1272.00
IUUC-Ptr-090800	Pan troglodytes	77.85	0.00e+00	1627.00
IUUC-Psi-093078	Pelodiscus sinensis	78.25	0.00e+00	1629.00
IUUC-Pma-094420	Petromyzon marinus	78.46	0.00e+00	902.00
IUUC-Pfo-096979	Poecilia formosa	70.99	0.00e+00	1090.00
IUUC-Pca-100874	Procavia capensis	96.05	0.00e+00	738.00
IUUC-Pva-102415	Pteropus vampyrus	77.75	0.00e+00	1576.00
IUUC-Rno-105682	Rattus norvegicus	76.18	0.00e+00	1567.00
IUUC-Sha-106711	Sarcophilus harrisii	76.81	0.00e+00	1524.00
IUUC-Ssc-115472	Sus scrofa	77.28	0.00e+00	1573.00
IUUC-Tgu-117037	Taeniopygia guttata	79.35	0.00e+00	1682.00
IUUC-Tru-118324	Takifugu rubripes	61.09	0.00e+00	1148.00
IUUC-Tsy-119216	Tarsius syrichta	92.53	0.00e+00	1111.00
IUUC-Tni-119950	Tetraodon nigroviridis	61.63	0.00e+00	1125.00
IUUC-Ttr-128209	Tursiops truncatus	78.25	0.00e+00	1639.00
IUUC-Xtr-132477	Xenopus tropicalis	71.38	0.00e+00	1061.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence