iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000015133.1	ENSAMET00000016649.1	ENSAMEP00000015982.1
ENSAMEG00000015133.1	ENSAMET00000016656.1	ENSAMEP00000015989.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-54	178.9	453	491
UBD/Beta-Prp	4.90e-65	219.7	324	525

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g l++s
   Q: 453  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGSLVHS 491
           9**********999******************9999875 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
            +v++ ++++ +a+ s+d +i v ++  g  +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++
   Q: 324  LDVDW-QNNTTFASCSTDMCIHVCRLGCGRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKW 411
           34445.55666666666666666666666666666666666666666666666666666666666666666666666666666666666 PP
   S: 103  sp.........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           sp         s+  l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ 
   Q: 412  SPtgpatsnpnSNIMLASASFDSTVRLWDVERGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG--TGG 497
           6655554444333456666666666666666666666.6666666666666666666666666666666666666666666666..666 PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlq 210
           +  + ++  g  + + + dg+v + dl+
   Q: 498  IFEVCWNARGDKVGASASDGSVCVLDLR 525
           6666666666666666666666666654 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

RLTEGGSRIV RTSSPRGEAK MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN 60
GTLVPPAALI SILQKGLQYV EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCTCACAG AGGGTGGCTC CCGCATCGTA CGGACCTCAT CGCCGCGAGG TGAGGCTAAG 60
ATGAGCATAA CCAGTGACGA GGTGAACTTC CTGGTGTATC GCTATCTCCA GGAGTCAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003232	Anas platyrhynchos	94.07	0.00e+00	993.00
IUUC-Aca-005035	Anolis carolinensis	91.90	0.00e+00	993.00
IUUC-Ago-007869	Ashbya gossypii	26.55	4.00e-39	155.00
IUUC-Bta-013202	Bos taurus	93.18	0.00e+00	994.00
IUUC-Cja-019281	Callithrix jacchus	89.94	0.00e+00	986.00
IUUC-Cfa-020929	Canis familiaris	95.44	0.00e+00	998.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.43	2.00e-131	462.00
IUUC-Csa-023943	Chlorocebus sabaeus	91.31	0.00e+00	998.00
IUUC-Cin-025704	Ciona intestinalis	72.30	0.00e+00	791.00
IUUC-Csv-026257	Ciona savignyi	71.03	0.00e+00	763.00
IUUC-Cne-026946	Cryptococcus neoformans	38.46	2.00e-30	127.00
IUUC-Dno-028926	Dasypus novemcinctus	92.60	0.00e+00	979.00
IUUC-Dme-031939	Drosophila melanogaster	81.74	3.00e-176	611.00
IUUC-Ete-032822	Echinops telfairi	84.01	0.00e+00	841.00
IUUC-Eca-033897	Equus caballus	95.06	0.00e+00	999.00
IUUC-Fca-036462	Felis catus	94.69	0.00e+00	998.00
IUUC-Fal-037388	Ficedula albicollis	92.93	0.00e+00	994.00
IUUC-Gga-040671	Gallus gallus	92.93	0.00e+00	994.00
IUUC-Gac-041851	Gasterosteus aculeatus	91.23	0.00e+00	933.00
IUUC-Ggo-045373	Gorilla gorilla	89.58	0.00e+00	993.00
IUUC-Hsa-045841	Homo sapiens	89.56	0.00e+00	1000.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	99.46	0.00e+00	779.00
IUUC-Kpa-049338	Komagataella pastoris	28.00	1.00e-31	130.00
IUUC-Lch-050535	Latimeria chalumnae	94.30	0.00e+00	975.00
IUUC-Laf-054071	Loxodonta africana	92.44	0.00e+00	992.00
IUUC-Mcc-055233	Macaca mulatta	91.34	0.00e+00	983.00
IUUC-Mga-059895	Meleagris gallopavo	92.75	0.00e+00	994.00
IUUC-Mvi-060557	Microbotryum violaceum	37.04	3.00e-70	259.00
IUUC-Mmr-061286	Microcebus murinus	92.83	0.00e+00	997.00
IUUC-Mmu-063447	Mus musculus	94.50	0.00e+00	995.00
IUUC-Nle-069151	Nomascus leucogenys	89.34	0.00e+00	995.00
IUUC-Ont-072252	Oreochromis niloticus	90.84	0.00e+00	952.00
IUUC-Oan-073562	Ornithorhynchus anatinus	92.79	0.00e+00	996.00
IUUC-Olu-087589	Ostreococcus lucimarinus	53.80	9.00e-157	546.00
IUUC-Oar-089506	Ovis aries	97.24	0.00e+00	1002.00
IUUC-Ptr-090793	Pan troglodytes	89.87	0.00e+00	941.00
IUUC-Pan-091909	Papio anubis	89.72	0.00e+00	999.00
IUUC-Psi-093358	Pelodiscus sinensis	93.20	0.00e+00	963.00
IUUC-Pma-094105	Petromyzon marinus	64.80	2.00e-102	364.00
IUUC-Pfo-097214	Poecilia formosa	89.47	0.00e+00	918.00
IUUC-Pab-098317	Pongo abelii	89.18	0.00e+00	977.00
IUUC-Pop-098989	Populus trichocarpa	57.93	2.00e-128	451.00
IUUC-Rno-105857	Rattus norvegicus	94.50	0.00e+00	995.00
IUUC-Sha-107326	Sarcophilus harrisii	95.90	0.00e+00	1003.00
IUUC-Sja-107844	Schizosaccharomyces japonicus	24.29	7.00e-29	121.00
IUUC-Sly-111042	Solanum lycopersicum	52.66	7.00e-151	526.00
IUUC-Ssc-115646	Sus scrofa	92.83	0.00e+00	1024.00
IUUC-Tgu-116898	Taeniopygia guttata	94.26	0.00e+00	994.00
IUUC-Tru-117862	Takifugu rubripes	91.26	0.00e+00	942.00
IUUC-Tni-119656	Tetraodon nigroviridis	91.52	0.00e+00	946.00
IUUC-Ttr-128826	Tursiops truncatus	94.00	0.00e+00	941.00
IUUC-Uma-129469	Ustilago maydis	43.53	2.00e-58	221.00
IUUC-Vvi-131193	Vitis vinifera	56.89	4.00e-129	454.00
IUUC-Xma-133591	Xiphophorus maculatus	89.32	0.00e+00	920.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence