iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098317

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01103119

Gene Name

TBL1X

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000020115.2	ENSPPYT00000023455.2	ENSPPYP00000022497.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-51	169.3	504	542
UBD/Beta-Prp	4.10e-63	213.4	381	546

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g+l++s
   Q: 504  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGNLVHS 542
           9**********999********************99886 PP

UBD/Beta-Prp

   S: 21   dksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           +                                                                                    + ++
   Q: 381  N------------------------------------------------------------------------------------NTTF 385
           3....................................................................................4455 PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng...... 192
           +s s d  i+v  l  +  ++ t++gh+  vn ++++p+g ll+s+s+D t+++W++k++ ++++l+  h++ +y ++++++g      
   Q: 386  ASCSTDMCIHVCRLGCDRPVK-TFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQA-HNKEIYTIKWSPTGpatsnp 472
           555556666665566666665.6666666666666666556666666666666666666666666655.66666666655555555555 PP
   S: 193  ...kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
                l+s+s d+tv+lwd+++g c +tl+ h+++v+sv+fsp++++l+sgs D+ + iW+++sg+l++++ ++
   Q: 473  nsnIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGT 546
           55555556666666666666666666666666666666666666666666666666666666666665555443 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MTELAGASSS CCHRPAGRGA MQSVLHHFQR LRGREGGSHF INTSSPRGEA KMSITSDEVN 60
FLVYRYLQES GFSHSAFTFG IESHISQSNI IGTLVPPAAL ISILQKGLQY VEAEISINED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCCGTGA GGGTGGAAGA AAATCATACC ATATCAGATG CCTCGCAGAG CACCAGGCCC 60
ACCGTGAAAG GTACAGCAAA TTTTACTTCC CTCTTCTTGC CTTGTTGGAA ATTCTTTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005876--C:spindle microtubule
GO:0005667--C:transcription factor complex
GO:0017053--C:transcriptional repressor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0045444--P:fat cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone
GO:0007605--P:sensory perception of sound

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001450	Ailuropoda melanoleuca	89.42	0.00e+00	983.00
IUUC-Apl-003232	Anas platyrhynchos	93.06	0.00e+00	958.00
IUUC-Aca-005035	Anolis carolinensis	91.98	0.00e+00	972.00
IUUC-Bta-013202	Bos taurus	94.24	0.00e+00	974.00
IUUC-Cja-019281	Callithrix jacchus	91.58	0.00e+00	1051.00
IUUC-Cfa-020929	Canis familiaris	93.64	0.00e+00	969.00
IUUC-Csa-023943	Chlorocebus sabaeus	97.37	0.00e+00	1103.00
IUUC-Dno-028926	Dasypus novemcinctus	92.31	0.00e+00	953.00
IUUC-Ete-032822	Echinops telfairi	82.88	0.00e+00	822.00
IUUC-Eca-033897	Equus caballus	94.80	0.00e+00	972.00
IUUC-Fca-036462	Felis catus	93.27	0.00e+00	966.00
IUUC-Fal-037388	Ficedula albicollis	93.45	0.00e+00	969.00
IUUC-Gga-040671	Gallus gallus	93.26	0.00e+00	969.00
IUUC-Ggo-045373	Gorilla gorilla	97.90	0.00e+00	1110.00
IUUC-Hsa-045841	Homo sapiens	99.47	0.00e+00	1120.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	95.89	0.00e+00	746.00
IUUC-Lch-050535	Latimeria chalumnae	89.98	0.00e+00	945.00
IUUC-Laf-054071	Loxodonta africana	93.30	0.00e+00	971.00
IUUC-Mcc-055233	Macaca mulatta	97.23	0.00e+00	1115.00
IUUC-Mtr-058624	Medicago truncatula	46.60	3.00e-134	472.00
IUUC-Mga-059895	Meleagris gallopavo	94.03	0.00e+00	969.00
IUUC-Mmr-061286	Microcebus murinus	93.88	0.00e+00	978.00
IUUC-Mmu-063447	Mus musculus	93.46	0.00e+00	970.00
IUUC-Nle-069151	Nomascus leucogenys	97.37	0.00e+00	1112.00
IUUC-Oan-073562	Ornithorhynchus anatinus	93.65	0.00e+00	972.00
IUUC-Oba-075618	Oryza barthii	48.46	1.00e-140	493.00
IUUC-Ogl-077302	Oryza glaberrima	50.27	5.00e-152	530.00
IUUC-Ogu-078718	Oryza glumaepatula	50.27	5.00e-152	531.00
IUUC-Oin-079515	Oryza indica	44.62	7.00e-95	341.00
IUUC-Ome-081696	Oryza meridionalis	49.19	1.00e-146	513.00
IUUC-Oni-082137	Oryza nivara	50.27	5.00e-152	531.00
IUUC-Opu-083505	Oryza punctata	48.27	3.00e-140	491.00
IUUC-Oru-085276	Oryza rufipogon	50.27	2.00e-152	532.00
IUUC-Osa-085791	Oryza sativa	50.27	5.00e-152	531.00
IUUC-Oar-089506	Ovis aries	92.29	0.00e+00	968.00
IUUC-Ptr-090793	Pan troglodytes	89.60	0.00e+00	922.00
IUUC-Pan-091909	Papio anubis	97.03	0.00e+00	1109.00
IUUC-Psi-093358	Pelodiscus sinensis	88.85	0.00e+00	927.00
IUUC-Pma-094105	Petromyzon marinus	61.88	3.00e-101	361.00
IUUC-Ppe-101572	Prunus persica	51.01	3.00e-142	498.00
IUUC-Rno-105857	Rattus norvegicus	93.46	0.00e+00	970.00
IUUC-Sha-107326	Sarcophilus harrisii	91.33	0.00e+00	976.00
IUUC-Stu-112786	Solanum tuberosum	47.91	2.00e-141	495.00
IUUC-Ssc-115646	Sus scrofa	93.67	0.00e+00	998.00
IUUC-Tgu-116898	Taeniopygia guttata	93.26	0.00e+00	960.00
IUUC-Tae-125368	Triticum aestivum	50.18	8.00e-152	530.00
IUUC-Tur-126856	Triticum urartu	43.38	1.00e-76	280.00
IUUC-Ttr-128826	Tursiops truncatus	91.52	0.00e+00	925.00
IUUC-Uma-129469	Ustilago maydis	43.14	7.00e-59	222.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence