iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000012102.3	ENSSSCT00000034442.1	ENSSSCP00000031017.1
ENSSSCG00000012102.3	ENSSSCT00000034620.1	ENSSSCP00000029636.1
ENSSSCG00000012102.3	ENSSSCT00000013237.2	ENSSSCP00000012883.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-53	177.0	473	511
UBD/Beta-Prp	3.40e-64	217.2	349	545

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g l++s
   Q: 473  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGSLVHS 511
           9**********999******************9999875 PP

UBD/Beta-Prp

   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.... 104
           ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++sp    
   Q: 349  QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPtgpa 437
           55666777777777777777777777777777777777777777777777777777777777777777777777777777777775555 PP
   S: 105  .....sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
                s+  l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ +  + +
   Q: 438  tsnpnSNIMLASASFDSTVRLWDVERGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG--TGGIFEVCW 523
           5554333567777777777777777777777.7777777777777777777777777777777777777777777777..777777777 PP
   S: 189  dsngkelvsgsldgtvklwdlq 210
           +  g  + + + dg+v + dl+
   Q: 524  NARGDKVGASASDGSVCVLDLR 545
           7777777777777777777765 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

XSGSRFVKTS SPPGEAKMSI TSDEVNFLVY RYLQESGFSH SAFTFGIESH ISQSNINGTL 60
VPPAALISIL QKGLQYVEAE ISINEDGTVF DGRPIESLSL IDAVMPDVVQ TRQQAFREKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGTGGCTC CCGCTTTGTA AAGACCTCAT CGCCGCCAGG TGAGGCTAAG ATGAGCATAA 60
CCAGTGACGA GGTGAACTTT CTGGTGTATC GGTATCTACA GGAGTCAGGT AAGAAGGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0016575--P:histone deacetylation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001450	Ailuropoda melanoleuca	92.46	0.00e+00	1024.00
IUUC-Apl-003232	Anas platyrhynchos	95.46	0.00e+00	1003.00
IUUC-Aca-005035	Anolis carolinensis	95.12	0.00e+00	1011.00
IUUC-Bta-013202	Bos taurus	97.54	0.00e+00	1017.00
IUUC-Cja-019281	Callithrix jacchus	91.18	0.00e+00	998.00
IUUC-Cfa-020929	Canis familiaris	98.30	0.00e+00	1009.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.43	1.00e-131	463.00
IUUC-Csa-023943	Chlorocebus sabaeus	93.20	0.00e+00	1004.00
IUUC-Cin-025704	Ciona intestinalis	71.96	0.00e+00	798.00
IUUC-Csv-026257	Ciona savignyi	69.57	0.00e+00	763.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	8.00e-31	128.00
IUUC-Dno-028926	Dasypus novemcinctus	96.41	0.00e+00	996.00
IUUC-Dme-031939	Drosophila melanogaster	81.74	2.00e-176	612.00
IUUC-Ete-032822	Echinops telfairi	83.77	0.00e+00	847.00
IUUC-Eca-033897	Equus caballus	98.68	0.00e+00	1014.00
IUUC-Fca-036462	Felis catus	97.54	0.00e+00	1011.00
IUUC-Fal-037388	Ficedula albicollis	95.65	0.00e+00	1014.00
IUUC-Gga-040671	Gallus gallus	95.46	0.00e+00	1014.00
IUUC-Gac-041851	Gasterosteus aculeatus	89.41	0.00e+00	938.00
IUUC-Gma-044208	Glycine max	48.60	2.00e-152	531.00
IUUC-Ggo-045373	Gorilla gorilla	93.57	0.00e+00	1008.00
IUUC-Hsa-045841	Homo sapiens	93.93	0.00e+00	1014.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	99.73	0.00e+00	784.00
IUUC-Lch-050535	Latimeria chalumnae	92.06	0.00e+00	981.00
IUUC-Laf-054071	Loxodonta africana	97.92	0.00e+00	1018.00
IUUC-Mcc-055233	Macaca mulatta	91.06	0.00e+00	988.00
IUUC-Mga-059895	Meleagris gallopavo	96.41	0.00e+00	1014.00
IUUC-Mvi-060557	Microbotryum violaceum	37.04	2.00e-70	260.00
IUUC-Mmr-061286	Microcebus murinus	96.60	0.00e+00	1021.00
IUUC-Mmu-063447	Mus musculus	97.35	0.00e+00	1011.00
IUUC-Nle-069151	Nomascus leucogenys	92.83	0.00e+00	1009.00
IUUC-Ont-072252	Oreochromis niloticus	89.41	0.00e+00	961.00
IUUC-Oan-073562	Ornithorhynchus anatinus	97.54	0.00e+00	1016.00
IUUC-Oba-075618	Oryza barthii	48.21	7.00e-141	493.00
IUUC-Ogl-077302	Oryza glaberrima	50.36	5.00e-153	533.00
IUUC-Ogu-078718	Oryza glumaepatula	50.36	5.00e-153	533.00
IUUC-Ome-081696	Oryza meridionalis	49.10	9.00e-149	520.00
IUUC-Oni-082137	Oryza nivara	50.36	5.00e-153	533.00
IUUC-Opu-083505	Oryza punctata	48.47	1.00e-143	503.00
IUUC-Oru-085276	Oryza rufipogon	50.36	1.00e-153	535.00
IUUC-Osa-085791	Oryza sativa	50.36	5.00e-153	533.00
IUUC-Olu-087589	Ostreococcus lucimarinus	50.91	4.00e-153	534.00
IUUC-Oar-089506	Ovis aries	95.27	0.00e+00	1010.00
IUUC-Ptr-090793	Pan troglodytes	92.06	0.00e+00	957.00
IUUC-Pan-091909	Papio anubis	93.05	0.00e+00	1014.00
IUUC-Psi-093358	Pelodiscus sinensis	91.70	0.00e+00	963.00
IUUC-Pfo-097214	Poecilia formosa	88.09	0.00e+00	929.00
IUUC-Pab-098317	Pongo abelii	93.63	0.00e+00	993.00
IUUC-Pop-098989	Populus trichocarpa	57.64	7.00e-129	453.00
IUUC-Ppe-101572	Prunus persica	63.69	5.00e-128	451.00
IUUC-Rno-105857	Rattus norvegicus	97.35	0.00e+00	1011.00
IUUC-Sce-106132	Saccharomyces cerevisiae	24.53	2.00e-39	157.00
IUUC-Sha-107326	Sarcophilus harrisii	94.71	0.00e+00	1019.00
IUUC-Sly-111042	Solanum lycopersicum	49.81	2.00e-149	521.00
IUUC-Stu-112786	Solanum tuberosum	48.04	4.00e-141	494.00
IUUC-Tgu-116898	Taeniopygia guttata	95.65	0.00e+00	1005.00
IUUC-Tru-117862	Takifugu rubripes	89.45	0.00e+00	952.00
IUUC-Tni-119656	Tetraodon nigroviridis	90.21	0.00e+00	952.00
IUUC-Tae-125368	Triticum aestivum	49.91	7.00e-154	536.00
IUUC-Ttr-128826	Tursiops truncatus	97.01	0.00e+00	952.00
IUUC-Uma-129469	Ustilago maydis	43.53	1.00e-58	221.00
IUUC-Vvi-131193	Vitis vinifera	56.89	4.00e-129	454.00
IUUC-Xma-133591	Xiphophorus maculatus	87.95	0.00e+00	932.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence